CN105724642A

CN105724642A - Anti-oxidation anti-aging dark tea composition and preparation method

Info

Publication number: CN105724642A
Application number: CN201610071481.4A
Authority: CN
Inventors: 贺志弘
Original assignee: Individual
Current assignee: Individual
Priority date: 2016-01-25
Filing date: 2016-01-25
Publication date: 2016-07-06

Abstract

Provided is an anti-oxidation anti-aging dark tea composition.The composition is prepared from materials, achieving homology of medicine and food, of Anhua dark tea, radix ginseng rubra, milkvetch roots, dried rehmannia roots, sweet barbary wolfberry fruit, radix ophiopogonis, radix asparagi, rhizoma polygonati, common yam rhizomes, fructus corni, herba epimedii, roots of kirilow rhodiola, flos rosae rugosae, cordyceps sinensis, white poria cocos, licorice roots and the like.The anti-oxidation anti-aging dark tea composition has the functions of delaying aging and prolonging the life and is wide in market prospect.

Description

The black tea composition of a kind of antioxidant and anti-aging and preparation method

Technical field

The present invention relates to the black tea composition of a kind of antioxidant and anti-aging, belong to food or functional food field.The preparation method that the invention still further relates to the black tea composition of a kind of antioxidant and anti-aging.The black tea composition of described antioxidant and anti-aging can improve the sub-health status of sub-health population effectively, to reach antioxidation, defying age, improves the quality of living, delaying cell aging, or delays the senescence process of sub-health population, life lengthening.

Background technology

Postfermented tea is China typical fermented tea of peculiar one, has the history of thousands of years.Having abundant tea polyphenols and Flavonoid substances in postfermented tea, postfermented tea has the health-care effect of significant antioxidation, blood sugar lowering, blood fat reducing.The main component of the Natural antioxidant is Flavonoid substances.Postfermented tea is as a kind of daily beverage, its extract also contains abundant antioxidants, can effectively remove interior free yl, immunocompetence can be improved, reduce cholesterol so that it is particularly have very prominent application to have broad prospects in the defying age of China, antioxidation market at medicine, field of food.

In recent years, country defends the correlation study data of the departments such as planning commission, the big data of the Chinese Central Television (CCTV), the big data of Baidu, Bai Cun investigation, zero point market and market researchy corporation and shows: along with the deterioration of social environment, chronic disease is ill, dead presents lasting, quick growth trend, the chronic made a definite diagnosis at present is more than 2.6 hundred million people, the composition accounting for China resident always dead because of chronic disease death has risen to 85%, and chronic disease proportion in Disease Spectrum has reached 70%.Chronic disease has become as affects China's residents ' health level raising, the great public health problem hindering socio-economic development and social problem.

Having 76% to be in subhealth state in Chinese inland cities, white collar, be in overwork state close to sixty percent, in the booming income crowd of 35 to 50 years old, physiological age average specific actual age old and feeble 10 years in advance, health status substantially reduces.

The survey data collecting the cities such as Beijing, Shanghai, Guangzhou, Nanjing shows, Beijing becomes the city that healthy pressure is maximum, and being number two in Guangzhou, row TOP V is divided in Shanghai, Shenzhen, Nanjing.Analytical data find, the white collar subhealth state ratio in main flow city reaches 76%, be in overwork state close to sixty percent, " Healthy People " ratio truly is extremely low (less than 3%).And cardiovascular system diseases problem rejuvenation trend is also on the rise.Related data at health examination high-end customer shows, these crowd's cardiovascular and cerebrovascular vessel and digestive system disease are occurred frequently, the booming income middle age white collar colony of 35～50 years old, organism aging process speed is higher than common job market white collar, " physiological age " overage trend was substantially accelerated, average more than " natural age " about 10 years.It is to say, middle age white collar carries previous decade and begins with evidence for senescence.

Chinese plutocrat has 81% to be in sub-health state, and only 7% belongs to healthy population, and 12% has all kinds of notable disease, and health level is significantly lower than society's average level.And pressure excessive 44% is to affect the main factor that Chinese plutocrat is healthy, next to that lack motion 25%, do not have enough sleep 15%, overworked 13% and diet irregular 5%.

Being easiest in the disease suffered from Chinese plutocrat, cardiovascular and cerebrovascular disease is the modal disease of Chinese plutocrat colony, and about 50% Chinese plutocrat has all kinds of cardiovascular and cerebrovascular disease, and this is also one of the reason of enterpriser's sudden death event increases in recent years.Mental illness and reproductive system disease are also need one of disease obtaining more attention, and Chinese entrepreneur faces increasing mental illness problem.But, the most concerned health problem of Chinese plutocrat is hypomnesis, next to that obesity, insomnia, gastropathy and sexual dysfunction, and these are all the signal that human body is old and feeble in advance undoubtedly.

Therefore, how defying age has obtained the great attention of China's sub-health population.

And currently with the mode of tea-drinking provide can antioxidant and anti-aging product, particularly fully excavate the active component of postfermented tea antioxidant and anti-aging and antioxidant and anti-aging active component organic compatibility in Chinese medicine and study, the antioxidant and anti-aging product developed is still a blank.

Summary of the invention

In view of this, the present inventor for a long time, at large have studied can antioxidation, defying age oriental medicine-Chinese medicine and pharmacy is theoretical and particularly integration of edible and medicinal herbs article and the antioxidation of postfermented tea, defying age material in Chinese medicine, aim to provide one and can realize antioxidation, defying age, delay technical scheme or the method for mankind aging's process, found that the black tea composition of a kind of antioxidation of the present invention, defying age is to improving level of human health, slow down aging, the quality of life promoting the mankind is effective.Therefore, an object of the present invention is just to provide the black tea composition of a kind of antioxidation, defying age, and another purpose is to provide its preparation method.

Technical solution

In order to realize the purpose of the present invention, provide comprise based on postfermented tea, particularly Fu-brick tea be main carriers, further comprises the black tea composition of the integration of edible and medicinal herbs class article such as Radix Ginseng Rubra, the Radix Astragali, Radix Rehmanniae, baogan medlar, Radix Ophiopogonis, Radix Asparagi, Rhizoma Polygonati, Rhizoma dioscoreae, Fructus Corni, Herba Epimedii, Radix Rhodiolae, Flos Rosae Rugosae, Cordyceps mycelium, Poria, Radix Glycyrrhizae simultaneously.

In order to realize the preparation method that objects of the invention, it is also provided the black tea composition of a kind of antioxidation, defying age.The preparation method of the compositions of the present invention includes, but are not limited to following steps:

(A) based on the postfermented tea of 100 weight portions, postfermented tea includes Fu-brick tea, black brick tea, green brick tea, ornamental slab for paving the floor tea, thousand tael tea, hundred liang of tea, sky point, raw point, tribute point, canal river thin slice and other product form.Fu-brick tea specifically preferred according to the invention.And the premise of a particular importance is, the GENE SOURCES of a good large leaf tea is selected to have highly important meaning for the present invention.

The present inventor, in long-term scientific research, once goed deep into a little basin of high mountain being named as duck ear lake for a long time.The inventors discovered that, Ya Erhu has abundant daye tea population gene bank.Ya Erhu pail dustpan gulf, peach tree ditch, hang many locations, well hole, be dispersed with shrub type (also having arbor type) daye tea population everywhere, its branch is partly carried out.The height of tree 1.5～2 meters, two meters of tree, branch is thinner, the long 12.07cm of average leaf, leaf width 4.65cm, length-width ratio 2: 6, and blade tip is tapering, and mesophyll is plump, and grand shape projection is obvious, and lateral vein average out to nine is right.Bud-leaf is stout and strong, yellow green, numerous hairs, holds tender property strong；Vein is sturdy, blade is big and meat is thick, water content is high.Daye tea product shape after processing solid tall and graceful, millifarad discloses, the fresh taste alcohol emerald green, aromatic of color and luster is long, brews rear soup color green gorgeous bright.This Camellia sinensis kind has all morphological characteristics of Camellia sinensis and Camellia sinensis functional components (tea polyphenols, aminoacid, caffeine etc.), owing to originating in High aititude cold district, this tea kind spy has the feature such as strong stress resistance, winter resistance You Qiang, is the precious resources of resistance breeding and molecular biology research.Pure with quality better, mouthfeel, return sweet fast, flavour just, soup color bright and famous；Local other daye tea provenance, Anhua County quality of Folium Camelliae sinensis not only soup color ratio produced to be got well, its tea molecular substance inclusions is enriched after testing, show no sign of the variety of problems existing for other tea-leaf producing areas, after testing, such as fluorinated volume, lead tolerance, be below national standard containing rare earth content.Its amino acid content is then at least high by about 17% than the tea raw material in other places of production.The present inventor therefrom gains enlightenment, and the change composition of postfermented tea raw material, proportioning are the effective ways that can change, promote black tea quality.Therefore, the present invention enters the first string completing the present invention first on this basis: selecting, optimizing the postfermented tea places of origin of raw materials is effective one create greatly.

The making of raw dark green tea:

The invention provides a kind of manufacturing technology rule producing raw dark green tea.It is science, is again the tea making marrow carried in tradition.

Fluorine technique drops in the washing of fresh leaf

As the first step, select " all sorts of flowers condensation " tea kind source, in stepping in setting up ANHUA HEI CHA quality control system, go out the first step of key.But the present inventors have additionally discovered that, take suitable washing process that reduction Oil repellent further is also had same effect.

The present inventor finds in the water-washing process test that kneading in brick tea raw material preliminary working process of the test increases in link many times, tea raw material now is after kneading, and cell wall crushes, by washing, a part of fluorine can be made soluble in water, thus the Oil repellent reduced in sampling tea.Washing relative to finished product tea, knead leaf undried, moisture is higher, does not need too many moisture during washing, and this is less on follow-up drying process impact.

But, knead leaf through washing, while reducing Oil repellent, the effective ingredient in Folium Camelliae sinensis has been also affected by a degree of loss.Especially the impact of the main components water extraction in Folium Camelliae sinensis, aminoacid, soluble sugar and catechin content is bigger.The Oil repellent of washing temperature and time meeting appreciable impact Folium Camelliae sinensis and the content of effective ingredient.Result of the test shows, under the identical time, the Oil repellent difference between 40 DEG C of washings, 60 DEG C of washings and room temperature washing process is not notable；And the Aqua Folium Camelliae sinensis extractum of 60 DEG C of washing 2min and amino acid content are substantially less than what room temperature washing 2min processed.Therefore, when washing, it is preferred that room temperature washing is 1～2min, it is possible not only to the Oil repellent effectively reducing in Folium Camelliae sinensis, and can retain the effective quality component in Folium Camelliae sinensis to greatest extent.And room temperature water need not heat, save the energy, less costly, on producing, there is certain practical value.

Three, present invention also offers ANHUA HEI CHA raw dark green tea manufacturing technology scheme:

Postfermented tea product be divided into sky point, tribute point, raw brick sharp, black, ornamental slab for paving the floor, FUZHUAN etc. several.Its quality of oolong tea generally requires profile bar rope convolution and straight, the black profit of color and luster, except there is pure tea perfume (or spice), and must also with special Colophonium smoke.In endoplasm requirement, it requires that soup color is orange, and fragrance is pure, and flavour is mellow, and at the bottom of leaf, Huang is unbuttoned or divest one's upper garment.First process processed includes completing, kneads, wet heap, rub again, five operations such as dry.

Raw dark green tea quality generally requires profile bar rope convolution and straight, and the black profit of color and luster, except should having blunt positive tea perfume (or spice), well is with special Colophonium smoke.Requiring that in endoplasm soup color is orange, fragrance is blunt just, and flavour is mellow, yellowish-brown at the bottom of leaf.The manufacturing process of raw dark green tea includes completing, kneads, wet heap, rub again, dry five processes.

(B), Radix Ginseng Rubra, the Radix Astragali, Radix Rehmanniae, Fructus Lycii, Radix Ophiopogonis, Radix Asparagi, Rhizoma Polygonati, Rhizoma dioscoreae, Fructus Corni, Herba Epimedii, Radix Rhodiolae, Flos Rosae Rugosae, Cordyceps mycelium, Poria, Radix Glycyrrhizae are included at interior Chinese medicine material based on integration of edible and medicinal herbs article, they can be a kind of or whole, preferably, 9 kinds or 11 kinds it are at least.Its weight portion is the Radix Ginseng Rubra of 30～90 weight portions, the Radix Astragali of 60～120 weight portions, the Radix Rehmanniae of 100～360 weight portions, baogan medlar of 70～150 weight portions, the Radix Ophiopogonis of 60～120 weight portions, the Radix Asparagi of 60～120 weight portions, the Rhizoma Polygonati of 70～150 weight portions, the Rhizoma dioscoreae of 70～150 weight portions, the Fructus Corni of 70～150 weight portions, the Herba Epimedii of 80～180 weight portions, the Radix Rhodiolae of 60～120 weight portions, the Flos Rosae Rugosae of 50～90 weight portions, the Cordyceps mycelium of 50～90 weight portions, the Poria of 30～70 weight portions, the Radix Glycyrrhizae of 20～50 weight portions.

Above-mentioned integration of edible and medicinal herbs mixtures of articles puts into extraction pot, and first time adds the pure water of medical material amount 10 times amount, decocts 2 hours；Second time adds the pure water of 8 times amount and decocts 1.5 hours.Merge with upper liquid, filter, be concentrated into relative density 1.12～1.25, standby after spraying drying powder-forming.

3, mixture:

By above-mentioned raw dark green tea 90%, add and raw dark green tea weight equivalent 10% extract powder, mix in proportion, stand-by.

4, tea compacting is steamed:

Weigh the compound of corresponding weight by the specification size of every block of brick tea to put into and steam tea machine, after 8～10 seconds steam, automatically fall into the black tea composition product that mould inner pressure makes a kind of antioxidant and anti-aging of the present invention.

5, dry in the sun sizing:

It is compressed on the brick tea in mould need to hang 3～4 hours, cooled brick tea can be about to cooling completely and exit in mould.

6, dry grow dim:

Being placed in by brick tea in the drying room of uniform temperature, humidity and be dried process, the strict drying room temperature that controls is at 28～30 DEG C, and relative humidity 80%, through the baking time of 6～15 days.And the inspection carrying out temperature and humidity whenever and wherever possible monitors.

7, finished product packing:

After sampled detection is qualified, select dry appropriateness, sanitation and hygiene, free from extraneous odour packaging material pack.

8, thousand tael tea, hundred liang of tea time are being produced, through by Folium Camelliae sinensis pile-fermentation 6～13 days, tea stack temperature 35～60 DEG C.

(C) preparation method of the present invention can also may further include step: when implementing step (B), the article of the integration of edible and medicinal herbs such as Radix Ginseng Rubra carries out the micronizing powder to average particle size particle size 0.3～2 μm.

In addition, when the product form of the present invention is capsule, a material agent or granule, can adding further and include pharmaceutically acceptable additive, this additive selects the group that free excipient, supplement, diluent, isotonic agent, preservative, lubricant, dilution auxiliary agent and mixture thereof form.

Passable product form is, when needed, it is possible to after being pulverized by the product form of such as Fu-brick tea so that it is become teabag.Or the product form such as thin slice, Tuo tea.

Beneficial effect:

Through trying out, the compositions of the present invention is of value to antioxidation, defying age；It is of value to and improves erection disturbance；It is of value to and losing weight；It is of value to resisting fatigue；It is of value to stamina intensifying；It is of value to enhancing blood circulation；It is of value to reduction blood cholesterol level；It is of value to enhancing immunity；It is of value to the release of zest hormone；It is of value to enhancing intestines and stomach, property or liver function.

Therefore, it is used as contributing to antioxidation, the food of defying age, health food or tea beverage, including slow down aging food/health food, or other food or health food, such as diet food/health food.

Detailed description of the invention

Below the preferred embodiments of the present invention are described.Following embodiment it will be apparent to those skilled in the art that: although illustrating the element much clearly specified in being described below, such as concrete composition, but they are used to help totally to understand the present invention, the present invention can also realize when not having these elements clearly specified.Additionally, in describing the invention, if it is determined that the detailed description of correlation technique makes the present invention's to want point fuzziness, and their these explanations are ignored.

The black tea composition of antioxidation, defying age is conducted extensive research by the present inventor, have found surprisingly that and add the extract of integration of edible and medicinal herbs article with the form of postfermented tea or this compositions that superfine powder form exists has antioxidation, anti-ageing slow down aging of waiting for a long time, the function such as extending life vigor, enhancing human body immunity power.

As the postfermented tea of main component in the present composition, there is following characteristic and efficacy of drugs.

Fu-brick tea be most characteristic in postfermented tea, there is the mainstream product of specific characteristic." growing dim " is the characteristic mark of Fu-brick tea, also it is the key technology of its production, by ferment " JINHUA " (the formal name used at school Eurotium cristatum) that formed, under the microscope in golden yellow, Form Sphere, it under suitable temperature and humidity condition can in Fu-brick tea growth promoter, and secrete a series of enzyme, promote Substance Transformation in Folium Camelliae sinensis, thus forming many functional components that human body is useful.Substantial amounts of research experiment shows, " JINHUA " in FUCHA and Ganoderma spore powder very similar, it can regulate human metabolism effectively, and have stronger blood fat reducing, blood pressure lowering, adjustment carbohydate metabolism, promote the effects such as body immunity, has good antioxidation, activity of fighting against senium.Drinking of the centuries of substantial amounts of historical document, scientific experiments and research and the our people masses also demonstrates that; demonstrating Fu-brick tea from different test angles is a member important postfermented tea family, has the special efficacies such as reduction human body class fatty compound, blood fat, blood pressure, blood glucose, cholesterol and diarrhea, whole the intestines and stomach, antioxidation, defying age, scavenging activated oxygen, protection cell oxidation damaged reactivity.

In recent years, substantial amounts of research shows, postfermented tea has the effect of scavenging activated oxygen, anti peroxidation of lipid.This is mainly likely due to postfermented tea and contains more tea polyphenols, and tea polyphenols can generate relatively stable Phenoxy radical with radical reaction, thus eliminates the free radical that activity is stronger, it is prevented that its damaging action；And competitively with combined with radical, terminate free radical chain reaction, prevent or alleviate the harm of free radical.As Liu Rong, Liu Shiquan etc. find in " research of postfermented tea ethanol extraction and its non-oxidizability ", having abundant tea polyphenols and Flavonoid substances in postfermented tea, the main component of the Natural antioxidant is Flavonoid substances.Result of study shows: within the specific limits, all strengthens gradually along with the content of black tea extract increases its inhibitory action and reducing power to free radical.When extracting liquid volume is 0.20mL, the suppression of hydroxyl radical free radical is reached to be 51.70% to the maximum by extracting solution, when exceeding this value, suppression ratio slightly declines, but reached 50.18%. when postfermented tea extracting liquid volume reaches 0.16mL, its peak that suppression ratio of DPPH free radical is reached is 87.44%, but after exceeding this concentration, it is suppressed that rate slightly declines.The reducing power of black tea extract, presents positive correlation=0.04033+2.00744V within the scope of finite concentration, and correlation coefficient is 0.99967.By result it can be seen that the oxidation resistance of postfermented tea is better.The research such as pharmaceutical college of Zhongshan University, Tea Inst., Guangdong Academy of Agricultural Sciences leaf fine jade celestial being, Liu Jing, Miao Aiqing, Wang Dongmei is thought, postfermented tea has the health-care effect of significant antioxidation, blood sugar lowering blood fat.They are with Baiyedancong postfermented tea 60% ethanol extract for object of study, obtain chloroform extract, acetic acid ethyl ester extract, n-butyl alcohol extract and water layer through solvent extraction and stay excess, wherein acetic acid ethyl ester extract has the highest general flavone content and total phenol content, for 155.68mgRE/g and 313.84ragGAE/g.Meanwhile, acetic acid ethyl ester extract has strong antioxidant activity and external hypoglycemic activity, and the EC of DPPH scavenging capacity is 13.721xg/mL, FRAP iron ion reducing power EC is 43.381xg/mL；It is 95.83% to α mono-pancreatic amylase suppression ratio under 5mg/mL concentration, is 91.30% to α mono-Glucosidase inhibitor rate under 50IXg/mL concentration.Analyze through HPLC-DAD-MS, deduce 12 compounds in acetic acid ethyl ester extract, wherein include Folium Camelliae sinensis alkaloid 3 kinds main, other be mainly the flavone glycoside constituents being aglycon with apigenin, kaempferol, also contain a small amount of free Flavonoids constituents.The material in Baiyedancong postfermented tea with strong anti-oxidative activity also has strong α mono-pancreatic amylase and α mono-glucosidase inhibitory active simultaneously.

University Of Science and Technology Of Tianjin's food engineering and Biotechnology Institute, Department of Engineering Physics of Tsing-Hua University particle technique and key lab of the radiant image Ministry of Education, Chemical and Biological Engineering College of Lanzhou Jiaotong University, the fourth gold of Beijing University Of Chinese Medicine Traditional Chinese Medicine College is auspicious, Huang Yun, Li Yong, Chen Na, Hao Pengfei, Tang Jingtian, Zhang Zesheng etc. are in " Study on extraction of Fu-brick tea anti-oxidation active substance ", select free radical scavenging activity (DPPH free radical), 2, 2 " double, two (3 one ethyl benzo thiazole phenanthroline 1 monosulfonic acid) di-ammonium salts (ABTS) radical scavenging activity and the reducing power etc. of-azino evaluates product antioxidation activity in vitro；Take into account efficiency of pcr product and antioxidant activity design orthogonal test, adopt the factor impacts on product such as different volume fraction of ethanols, temperature, solid-liquid ratio and extraction time of Multi-index scoring method systematic study.Result shows that Fu-brick tea ethanol extraction has good antioxidation activity in vitro, DPPH, ABTS radical scavenging activity of gained crude extract and reducing power and positive reference substance Vc is suitable.

In sum, postfermented tea has the effect of good antioxidation, resisting fatigue.This is for promoting human health, and slow down aging is significant.

Equally, as the Radix Ginseng Rubra of main component, the Radix Astragali, Radix Rehmanniae, Fructus Lycii, Radix Ophiopogonis, Radix Asparagi, Rhizoma Polygonati, Rhizoma dioscoreae, Fructus Corni, Herba Epimedii, Radix Rhodiolae, Flos Rosae Rugosae, Cordyceps mycelium, Poria, Radix Glycyrrhizae in the present composition, there is following characteristic and efficacy of drugs.

Radix Ginseng Rubra: Radix Ginseng is the tuber of Araliaceae herbaceos perennial Radix Ginseng (PanaxginsengC.A.Mey).

If it is known that free radical produced by normal metabolic processes can quickly be removed by body defending system, not resulting in harm, as not being eliminated completely, then biomacromolecule can be made to be damaged, cause human senility.Existing result shows, ginsenoside both can suppress the generation of free radical, it is possible to the damaging action of facedown radical pair tissue and cell, or direct scavenging free radicals, also can the function of the antioxidant system of enhancing body own, block the damaging action of free radical from multiple links.Antioxidase activity influence research in aged rats blood is shown ginsenoside Rb1 by Zhang Jialin etc., Rg1 all can significantly improve superoxide dismutase (SOD) and catalase (CAT) vigor, enhance the ability of body defenses toxic oxygen radicals damage, there is the effect of defying age.Wang Hongli etc. find when carrying out ginsenoside's anti aging effect effect experiment, oral ginsenoside 100mg/kg d makes SOD vigor in the exhausted mining areas skin caused by D mono-galactose, hydroxyproline content significantly raised, malonaldehyde (MDA) content significantly reduces, in blood, CAT, glutathion peroxidase (GSH2Px) vigor significantly raise, its mechanism generates ruscogenin, i.e. panoxadiol, panaxatriol, oleanolic acid etc. after being likely ginsenoside's hydrolysis.Particularly ginsenoside Rb1 and Rg1, it is main reactive compound in Radix Ginseng, these materials can promote the metabolism of cell, accelerate the synthesis of ageing skin nucleus and protein, increase SOD content and activity in skin simultaneously, play its powerful antioxidation and effect of scavenging radical, reduce the deposition of lipid peroxidation product such as MDA, recover the normal physiological function of cell, and ginsenoside also can stimulate the activity of skin flbroblast, promote collagen protein synthesis, make skin tend to rejuvenation, thus delay skin aging process.The experiment such as Chang show that panoxadiol induces SOD and CAT gene expression to be 2～3 times of total saponins, the most obvious with the effect of ginsenoside Rb2, thus demonstrating ginsenoside's pivotal role to antioxidase regulation and control on gene level.Zhang Xinmu etc. on ginsenoside-Rb on the impact of hyperlipidemia rats blood lipid metabolism and the research of antioxidation thereof in find, ginsenoside-Rb can significantly improve the activity of SOD, reduce lipid peroxide (LPO) and metabolite MDA content, delaying senility course.Cheng Junlin etc. find when observation stem and leaf of Radix Ginseng total saponins is administered orally the anti-aging effects to skin, 100mg/kg d stem and leaf of Radix Ginseng total saponins can make CAT and GSH2Px vigor in mouse aging whole blood significantly raise, in skin histology homogenate, SOD vigor significantly raises, MDA content reduces, 50mg/kg d and 100mg/kg d stem and leaf of Radix Ginseng total saponins all can make hydroxyproline content in mouse aging skin histology raise, and compare with aging model group and to have significant difference, it is believed that the mouse skin that D mono-galactose is induced by oral stem and leaf of Radix Ginseng total saponins has anti-aging effects.

The Radix Astragali: the Radix Astragali is sweet, tepor, return spleen, lung meridian, there is the effect of strengthening superficial resistance to stop perspiration, benefiting qi and raising yang, wind dispelling fortune poison, promoting pus discharge and tissue regeneration strengthening and inducing diuresis to remove edema, it is widely used clinically, it is mainly used in the treatment of the people of yang deficiency, typhoid fever, the disease of harmful wind, the card of carbuncle and ulcer, dysentery foul leukorrhea person and blood fortune impassable patient, and effect is notable.

Result of study shows, the Radix Astragali has enhancing non-specific immunity function: the Radix Astragali not only has in increase blood from the function of total cellular score, it is also possible to promote phagocytic function and the sterilizing ability of neutrophilic granulocyte and macrophage.

The Radix Astragali can strengthen specific immune function: the Radix Astragali has enhancing cellular immune function, promotes that the caused lymphocyte of PHA, COnA, PWM of internal body converts.Modern pharmacology shows, the Radix Astragali itself has certain immunosuppressive action.

In the Effect study slowing down naturally-aged, foreign study shows, the Radix Astragali has important function for the average life prolongation of silkworm and fruit bat, there is the composition of delaying senility in the prompting Radix Astragali.It addition, the Radix Astragali also has certain antioxidation, this is mainly by the liver lipofuscin content reduced in animal serum and what LPO realized.

In the effect on human body of slow down aging, the increase of free radical is old and feeble main cause, prove through experiment, the Radix Astragali total former times and polysaccharide can substantially reduce monoamine oxidase, MAO one B activity in person in middle and old age's mouse brain, alleviate because this enzymatic activity caused by aging increases, improve Central Catecholamine level.By enhancing human body immunity function, the effect improving its slow down aging of Function such as antioxidant ability of organism and direct scavenging free radicals.

Radix Rehmanniae: refer to scrophulariaceae rehmannia glutinosa plant (RehmanniaglutinosaLibosch).Its sweet in the mouth, cold.GUIXIN, liver, kidney channel.Clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting.

Old and feeble correlational study is found, immune functional status has very close relationship with old and feeble generation and development, the problem that immune system itself there is also old and feeble degeneration, this function of immune system declines, causing that the resistance that disease is infected by body weakens, it is exactly an illustration that old people's autoimmune disease increases.Walford proposes old and feeble immunological theory accordingly, it is believed that aging is to cause that body tissue's immunologic tolerance weakens even lose due to immune system cell sudden change, and autoimmune and the result of long-term low tissue incompatibility reaction then occur.Due to immunologic function degenerate and old and feeble substantial connection is generally acknowledged by numerous scholars, people begin one's study the method from immunology angle defying age very early: as suitably used immunosuppressant, vitamin E and thymosin etc..In recent years finding that Radix Rehmanniae has the effect strengthening old body's immunity, Radix Rehmanniae compound recipe and single Radix Rehmanniae all have raising body Peritoneal Macrophage Phagocytosis, strengthen cellular immune function effect, thus reaching to improve Abwehrkraft des Koepers, effect of defying age.

In sum, Radix Rehmanniae realizes effect of defying age by multi-faceted effect, and its defying age mechanism relates to multiple old and feeble etiology such as free radical, immune function, neuroendocrine, DNA damage reparation, has the advantage of uniqueness in defying age.

Fructus Lycii: Compendium of Material Medica is recorded: " the hard muscles and bones of clothes for a long time, makes light of one's life by commiting suicide not old, and resistance to cold and summer-heat mends vital essence various symptoms and signs of deficiency, and easy color bleaches, and improving eyesight is calmed the nerves, and makes us long-lived ".Fructus Lycii has the effect of nourishing liver and kidney, replenishing vital essence to improve eyesight.Modern medicine study finds, Fructus Lycii has anti-ageing life-prolonging, promotes the effect such as immunologic function, anticancer growth.Experiments show that of immunology, physiology, biochemical and hereditism's functional status etc., Fructus Lycii can improve and improve the many index of old people so that it is reverses to rejuvenation direction；Fructus Lycii and lycium barbarum polysaccharide can significantly extend the average life of fruit bat and mice, but on the two maximum life span all without impact.

Liu Rui, Xu Chen, Shi Chunyue, Chen Qianjuan, Zhang Min, in the antioxidant activity of lycium barbarum polysaccharide and the hydrolyzate thereof " research ", utilize the monosaccharide of gas chromatogram, atomic force microscope and antioxidation in vitro experimentation FLP and hydrolyzate thereof to form, molecule pattern and antioxidant activity.It is shown that acidolysis and enzymolysis all can make lycium barbarum polysaccharide molecule reduce, but owing to acidolysis makes glucuronic acid content improve, causing that molecular aggregation improves, molecule aggregate particle diameter increases；Lycium barbarum polysaccharide is relevant with glucuronic acid content in polysaccharide and protein content to the inhibitory action of liposome peroxidation, and along with the minimizing of the raising of glucuronic acid content and protein content, the ability of lycium barbarum polysaccharide anti-peroxidation also improves accordingly.

Institute of Botany, Chinese Academy of Sciences (Jiangsu), Nanjing wild plant comprehensive utilizating research institute Qian Xue penetrate, Zhang Weiming, Jin Jiuning, HUANG Jingjing etc. review the effect of Fructus Lycii slow down aging etc..Fructus Lycii can increase leukocyte and Neutrophil numbers, strengthen the phagocytic function of macrophage, improve the biosynthesis of splenocyte nucleic acid and protein, promote the generation of interleukin II, promote marrow hemopoietic stem cells propagation, suppress the generation of lipid peroxide, improve the activity of glutathion peroxidase and superoxide dismutase；And there is plan choline-like effect: reduce serum cholesterol, it is suppressed that arteriosclerosis etc..Clothes can postpone the aging of body for a long time.

Radix Ophiopogonis: nature and flavor hardship sweet, micro-, be slightly cold. GUIXIN, lung, stomach warp, there are nourishing YIN and moistening the lung, nourishing the stomach to promote the production of body fluid, clear away heart-fire relieving restlessness, the merit of loosening bowel to relieve constipation.This product is sweet trembles with fear into lung, dry for lung moistening, supports lung yin common drug.Compendium of Material Medica says its " curing mainly stagnation of QI in chest and abdomen, damaging the spleen and stomach wound is full, and stomach channels is exhausted, becomes thin and loses heart "." Bencao Congxin " says its " lung moistening clears away heart-fire, relieving restlessness of purging heat, and reduce phlegm row water "." Mingyi Bielu " Yan Qizhu " asthenia exopathogenic heat, dry mouth is thirsty, anti-nausea, more flaccidity with cold limbs, reinforcing YIN-essence benefit essence, during rapid digestion of food is adjusted, protects god, determines lung qi, the five internal organs "." big bright book on Chinese herbal medicine " say its " antitussive. control consumptive lung disease vomiting pus "." medicineization justice " speech " Radix Ophiopogonis color lean type profit, main lung moistening, sweet in the mouth, cool in nature, main lung heat clearing. lid the lung being apt to suffer from adverse rising of QI. profit clearly it. lung qi must be protected ".

The Advance on Pharmacological Activities of Radix Ophiopogonis has been carried out combing by Zhou Fubo, it is believed that Radix Ophiopogonis anti-aging effects is notable.When the Radix Ophiopogonis decocting liquid gavage that dosage is 3g/kg can resist the rat cerebral tissue SOD that D mono-galactose causes, significantly reducing of hepatic tissue GSH-Px activity and significantly raising of Liver MDA, the Rat Erythrocytes SOD activity that D mono-galactose causes can be resisted when dosage is 6g/kg. soluble transferring receptor and hematid immunity function significantly reduce that (model group compares with matched group: model group rats C 3 b receptor of red blood cells rosette rate, Erythrocytes cancer cell rosette significantly reduces, and RBC immune complex flower rate rate significantly raises) and the notable rising of Content of MDA, additionally, M mono-receptor up-regulation effect is also had trend by Radix Ophiopogonis, prompting Radix Ophiopogonis can reduce body radical reaction and play anti-aging effects.Arrhythmia intravenous injection 10rag/kg Radix Ophiopogonis total saponins can prevent or resist by chloroform one epinephrine (rabbit), BaCl:(rat) and the arrhythmia brought out of aconitine (rat), and make the ventricular arrhythmia incidence rate after following coronary artery occlusion 24b be down to (57+7) % by (87+8) %, thus proving that Radix Ophiopogonis has antiarrhythmic effect, total saponins is one of its active ingredient.

Xu Huiyu, Yu Gang, Zhang Yishui, Liu Xiangzhong, Li Hua etc. are in " research to red cell immune function in rat and anti-aging effects of the Chinese medicine Radix Ophiopogonis ", have studied the Radix Ophiopogonis impact on aging model red cell immune function in rat, RBC-C3b, RBc-CaR height represents erythrocyte b in the sixth of the twelve Earthly Branches receptor active, the content of circulating immune complex in the high low reaction serum of RI3C-ICR.Test result indicate that. Radix Ophiopogonis can significantly improve the hematid immunity function of rat model, shows as RBC-c3bRR, RBC-c and increases so that the adhesion Scavenging activity of circulating immune complex is strengthened by erythrocyte. and in serum, RBC-ICR content hip is low.Result shows: decocting chaste tree can significantly improve Radix Ophiopogonis: the erythrocyte (SOD) of rat model activity, serum T from and hematid immunity function, significantly reduce Content of MDA.Prompting Radix Ophiopogonis has certain anti-aging effects.

Radix Asparagi: (Asparaguscochinchinensis (Lour.) Merr for Liliaceae asparagus plant, has another name called Radix Asparagi, is the tuber of Liliaceae herbaceous plant Radix Asparagi for many years, is preferred with grossness, densification, yellow-white, translucent person.The traditional Chinese medical science is thought. Radix Ophiopogonis nature and flavor hardship sweet, micro-, be slightly cold, GUIXIN, lung, stomach warp, have nourishing YIN and moistening the lung, nourishing the stomach to promote the production of body fluid, clear away heart-fire relieving restlessness, the merit of loosening bowel to relieve constipation.This product is sweet trembles with fear into lung. and dry for lung moistening, support lung yin common drug.

At present the research of Radix Asparagi oxidation resistance is concentrated mainly on internal, studies have found that, lucid asparagus extract and Aqueous extracts all can significantly reduce mouse liver cell film MDA level, its alcohol extract can significantly improve NOS and SOD activity in Mice brain tissues, NO level is made to increase, activity that Aqueous extracts can be obviously enhanced in mice serum NOS, improves NO level.The radical scavenging activity of Radix Asparagi Aqueous extracts strengthens with the increase of mass concentration；DPPH and ABTS radical scavenging activity lower than BHT and Vc, is neutralized high concentration extracting solution and the Scavenging activity of hydroxyl radical free radical and ultra-oxygen anion free radical is not less than BHT and Vc by high concentration extracting solution.Radix Asparagi Aqueous extracts has stronger antioxidant activity in vitro.Therefore Radix Asparagi is as dietotherapeutic health plant, it is possible to eat together with other foods, reaches to remove interior free yl, antioxidation and effect anti-aging in advance.

Rhizoma Polygonati, sweet in the mouth, property is put down.Return spleen, lung, kidney channel.Energy boosting qi and nourishing yin, spleen invigorating, lung moistening, kidney tonifying.For deficiency of spleen-QI and stomach-QI, fatigue and asthenia, deficiency of stomach-Yin, xerostomia lack of appetite, deficiency of the lung cough caused by dryness, chronic cough hemoptysis, asthenia of essence and blood, soreness of the waist and knees, early whitening of beard and hair, interior-heat is quenched one's thirst.

Intercalation letter is beautiful, Lu Jianmei, Wang Yanfang, Shang Yunqing, and Yu Jie etc., in " Rhizoma Polygonati regulates glycometabolic activity and Study on mechanism progress " literary composition, illustrates Rhizoma Polygonati effect in antioxidation.Author thinks, long-term carbohydrate metabolism disturbance may result in the unbalance of mice body oxidative stress and anti-oxidative defense system.P. kingianum total flavones has the reducing power more higher than homogenous quantities concentration rutin, and along with the increase reducing power of mass concentration is enhancing trend.The reducing power of a kind of material can reflect the antioxygenic property that this material is potential.And the material with reducing power is typically all the donor of electronics, it is possible to the intermediate oxidation product in reduction lipid peroxidation process, therefore there is primary or secondary antioxidation.So P. kingianum flavone as electronics and proton donor, can terminate radical chain reaction, get good antioxidation.Polygonatum polysaccharide can correct the diabetic mice serum of alloxan induction and the ANOMALOUS VARIATIONS of superoxide dismutase from liver (T-SOD) and glutathion peroxidase (GSH-Px) activity and malonaldehyde (MDA) content to a certain extent, helps to recover the normal oxidation resistance of body.

Rhizoma dioscoreae: have another name called Rhizoma Dioscoreae, for the plant of medicine-food two-purpose, records in 2010 editions " Chinese Pharmacopoeias ", sweet in the mouth, and property is put down.Return spleen, lung, kidney channel.Energy spleen reinforcing nourishing the stomach, promote the production of body fluid lung benefiting, the kidney invigorating arresting seminal emission.For insufficiency of the spleen lack of appetite, loose stool of having loose bowels, the deficiency of the lung is breathed with cough, emission due to deficiency of the kidney.Chen Xiaojun, Zhang Ying, Li Yanjing, Chen Xuefen etc. have studied the Rhizoma Dioscoreae effect to defying age, they think, aging is the basic inherent physiological feature of human organism's life, and it relates to multisystem systems such as () metabolism, immunity, urogenital, endocrine, cardiovascular, nerve, breathing, digestion, multiple organ dysfunction and form and the decline to internal and external environment adaptive faculty and organism metabolism function.In Rhizoma Dioscoreae oral liquid side, Rhizoma Dioscoreae sweet in the mouth is put down, benefit of reinforcing the kidney essence, moistens blood vessels, has effect of anti-senility；Fructus Lycii nourishing the liver and kidney, Arillus Longan benefiting QI and nourishing blood, Colla Corii Asini nourishing blood YIN nourishing, Semen Sesami Nigrum benefiting essence-blood, Fructus Jujubae invigorating the spleen and replenishing QI, all medicines share composition compound preparation.This experimental studies results shows, Rhizoma Dioscoreae oral liquid can be obviously prolonged drosphila metanogaster, has the effect of slow down aging, life-saving.The aging degree of human organism and immunologic function reduce degree and are proportionate, and during human organism's aging, the reduction of immunologic function is mainly manifested in going down of immunologically competent cell function.Rhizoma Dioscoreae oral liquid can be remarkably reinforced the phagocytic function of mononuclear phagocyte system, has the effect improving immunologic function.Sexual function goes down with human organism's aging, and sexual hypofunction is one of old and feeble important behaviour.Rhizoma Dioscoreae oral liquid can improve male mice mating ability, has the effect improving Sexual potency.In sum, Rhizoma Dioscoreae oral liquid has slow down aging, life-saving, improves immunologic function, improves the anti-aging effects of Sexual potency, provides pharmacodynamic experiment foundation for its clinical practice.

Fructus Corni: for the drying and ripening sarcocarp of Cornaceae defoliation small arbor plant Fructus Corni (CorflUSoficinalisSieb.etZuec.), has another name called Fructus Corni, Rhizoma Dioscoreae, medicine Fructus Jujubae, meat Fructus Jujubae (Compendium of Material Medica), real Fructus Jujubae (herbal for Relief of Famines) etc..It hides acid, puckery, tepor, return liver, kidney channel, function liver and kidney tonifying, essence astringing and desertion stemming.Fructus Corni has more than 2000 years medicinal history, begin to be loaded in Shennong's Herbal " controlling pathogen cold and heat under the heart; warming middle-JIAO, by cold-damp numbness, goes three worms, clothes are made light of one's life by commiting suicide for a long time ", later age is recorded more detailed with the Compendium of Material Medica of Ming Dynasty's Li Shizhen (1518-1593 A.D.) in medical book, think the flat taste of urosolic acid, nontoxic, have " warming middle-JIAO, by spleen cold, wet, go turbid, reinforcing YIN-essence, benefit essence; take improving eyesight, brute force, longevity for a long time " etc. effect, be the rare Chinese medicine of traditional reinforcing YIN-essence benefit essence smart, the secret solid and gas of China.It is clinically used for interior-heat to quench one's thirst, vertigo and tinnitus, soreness of waist and knee joint, impotence and seminal emission, urine enuresis frequency, bleeding not during menses, profuse sweating collapse etc..

Parsley, Zhu Guiming have studied skunk bush polysaccharide delaying senility function, it is believed that: China's tradition famous medicine Fructus Corni (Fructuscomi) belongs to the convergence antasthenic of invigorating the liver and kidney, arresting seminal emission gas.Its main chemical compositions has iridoid glycosides, Pentacyclic triterpenic acid, tannin class, polysaccharide, organic acid and microelement kind etc..Research finds, Fructus Corni is improved immunity of organisms, reduces the effects such as blood glucose, shock, antibacterial, antitumor.They all can pass through the hypofunction of cell when number of ways is improved old and feeble.These researchs disclose Fructus Corni and age-related diseases and aging all can be played good intervention effect, not only have the value of research further, and have extraordinary potentiality to be exploited and prospect.

Herba Epimedii: for the traditional tonic medicine of Chinese tradition, history tree is all on the books, begins to be loaded in Shennong's Herbal, calls Herba Epimedii, for Berberidaceae (Berberidaceae) Epimedium (EpimediumL.) plant.Compendium of Material Medica is recorded: its stem, leaf are used as medicine, and Xin Wen is nontoxic, has hard muscles and bones, benefit vital essence, mends the effect such as waist knee joint, heart tonifying power.Containing multiple chemical composition, mainly include the trace element such as zinc, copper, calcium, manganese etc. of flavone compound, polysaccharide, lignanoid, oleic acid, linolenic acid, alkaloid, volatile oil and some necessity.Flavone compound is main bioactive ingredients, and wherein icariin is the index of epimedium herb qualitative, quantitative.Modern pharmacology research proves that Herba Epimedii has the effects such as anti-erection disturbance, osteoporosis, adjustment immunity, antitumor, defying age, tranquilizing soporific, memory protection.

The effective ingredient of Herba Epimedii has Estrogenicity-like effect, it is possible to raise the expression of hormone receptor, increases the expression of matrix metalloproteinase (MMP), reduces injury of testis, has the effect of the kidney invigorating.King waits quietly observing the icariin impact on ovariectomized mouse uterus, it has been found that it has Estrogenicity-like effect, can improve the Uterine coefficient of ovariectomized mouse, endometrium thickness, uterus body of gland diameter.

The pharmacological action of Herba Epimedii has been carried out following summary by Sun Xianming, Chen Yuan etc..Think that Herba Epimedii has the effect of good defying age.

Extraction ofHerba Epimedii has injury of kidney tool protective effect, can suppress the rising of creatinine and urea nitrogen levels in blood, it is suppressed that the generation of renal cortex peroxide and alleviate the exhaustion of glutathion, and its mechanism is likely to relevant with lipoid peroxidization resistant.Herba Epimedii has obvious antioxidation, Free-radical scavenging activity, anti-ageing life-prolonging effect.

Radix Rhodiolae: for the dry herb of Crassulaceae rhodiola herbaceos perennial Radix Rhodiolae.Radix Rhodiolae mainly contains rhodioside, tyrosol and Radix Rhodiolae polysaccharide, and containing fat, sterol, phenolic compound, organic acid, tannin, multiple micro-element and water solublity volatile oil；Additionally, also include 18 seed amino acids such as aspartic acid, threonine serine, glutamic acid；35 kinds of inorganic elementss such as magnesium, calcium, potassium, phosphorus；The macro-and trace-element ferrum of 15 kinds of needed by human, aluminum, zinc, cobalt, manganese etc..Radix Rhodiolae has hypermnesis, improves cardio-cerebrovascular function, strengthens immunity, resisting fatigue, defying age, anoxia enduring, antitumor, blood sugar lowering, antiviral, resisting microwave radiation, armour from many-side pharmacological actions such as radical damages.

Miao Yanbo and Zhang Li etc. test result indicate that, Radix Rhodiolae and Total saponin thereof can significantly improve aged mouse erythrocyte sod and CAT vigor, improve the power of GSH.Px in hepatic tissue, substantially reduce Aged Mice contents of mda, suppress the generation of lipofuscin in hepatic tissue, it was shown that Radix Rhodiolae and Total saponin thereof can make the ability of body scavenging free radicals be remarkably reinforced, and alleviate body lipid peroxidation, reduce biomembranous extent of peroxidation, thus preventing and delaying body aging.

Above-mentioned test result indicate that Radix Rhodiolae has the effect of tonifying speen and tonifying kidney, QI invigorating and blood producing, protection cell and slow down aging.

Flos Rosae Rugosae: for the dry flower of rosaceous plant Flos Rosae Rugosae (RosarugosaThumb), it is also possible to be polyphyll red rose Roserugosacv.Plena；Flos Rosae Rugosae nature and flavor hardship sweet, micro-, temperature.

Shao Wei, Liu Zhaokun, Liu Fang etc. are with fruit bat for animal model, to Flos Rosae Rugosae extract (F₂₁) carry out the research that antioxidation is anti-aging. by large sample, the high life experiment repeated, it was demonstrated that F₂₁Average life and the maximum life span of fruit bat can be significantly improved. use F₂₁After raising (culture medium administration concentration 0.2) fruit bat, the lipofuscin content in its process group fruit bat body is decreased obviously, flight frequency has obvious rising trend；Meanwhile, in fruit bat body, the vigor of antioxidase CAT and SOD is all significantly improved.The results show F₂₁Drug treating group antioxidase activity, apparently higher than matched group, illustrates in fruit bat body, F₂₁The free radical scavenging effect of antioxidant system can be improved.The assay of lipofuscin MDA cell-cytotoxic reaction product proves that F21 significantly reduces the lipofuscin level in fruit bat body, can play the effect of the level of lipid peroxidation reducing film, protect the normal function of film, play the effect of defying age.

Shandong Traditional Chinese Medicine University Liu Hong swallow have studied " activity of Flos Rosae Rugosae tannin extract antioxidation in vitro ", author adopts Fenton system and assay NBT photoreduction to have rated the antioxidant activity in vitro of Flos Rosae Rugosae tannin, and during employing multiple linear regression, tannin concentration has been analyzed with antioxidant activity dependency.Result: Flos Rosae Rugosae tannin extract concentrations within the scope of 0.05-4.00g/mL with p-OH and O^2-Scavenging activity is dose-effect relationship, its maximal clearance respectively 62.85% and 72.67%；The linear of oxidation resistance is returned equation y=0.517+1.732X by concentration₁-0.903X₂。

Conclusion: Flos Rosae Rugosae tannin has stronger oxidation resistance, is a kind of natural effective antioxidant.

Cordyceps: it is warm in nature, it is sweet to hide, flat, enters lung, kidney channel, has kidney tonifying tonifying the lung, and benefit vital essence, tonifying deficiency, cough-relieving is coughed, effect of hemostasis and phlegm.Pharmacological research shows that Cordyceps has the multiple pharmacological effect such as defying age, antiviral, antitumor, antioxidation, adjustment immunity, blood pressure lowering, endocrine regulation.

The auspicious ring in Capital University of Medical Sciences hole, Wang Hong etc. in " experimentation of cordyceps sinensis nutrient solution anti-aging effects ", adopt animal in vitro tests method, have studied the effect of cordyceps sinensis nutrient solution defying age.Result shows: cordyceps sinensis nutrient solution in vitro has and substantially suppresses the effect that too Hepar Mus homogenate lipid peroxide (LPO) generates, and well is dosage one reaction relation.The visible cordyceps sinensis nutrient solution of In-vivo test in mice substantially suppresses liver LPO to generate, well make erythrocyte superoxide dismutase (SOD) vigor increase experimental result prompting fermentation cultivate cordyceps sinensis nutrient solution there is anti-aging effects.Result of study discloses Chinese caterpillar fungus nurient liquor all has obvious inhibiting effect to the generation of LPO in liver inside and outside animal body.SOD has been the enzyme of catalytic action, the ultra-oxygen anion free radical that organism metabolism produces can be carried out disproportionation, have the ability of scavenging free radicals so that it is disproportionation strengthens 1O times.Old and feeble and some damages can make the LPO of tissue increase, as given SOD or vitamin E in advance, it is possible to prevents from and alleviate this phenomenon occurring.SOD can stop lipid peroxidation chain reflex, and the height of its enzymatic activity is all closely related with aging.This laboratory observation can improve the vigor of mouse red blood cell SOD to the high dose group of Chinese caterpillar fungus nurient liquor.LPO is suppressed to generate and the effect of enhancing erythrocyte sod vigor when optimal dose by this research it is believed that artificially cultivating cordyceps nutritional solution has, thus having anti-aging effects.And then prompting, informal dress Chinese caterpillar fungus nurient liquor not only protects lung kidney tonifying, it is also possible to life lengthening.

Poria: for the dry sclerotia of On Polyporaceae Poria (PoriaCOCOS (Schw.) Wolf), is the conventional big kind of medicine-food two-purpose Chinese medicine.Poria records in version over the years " Chinese Pharmacopoeia ", sweet in the mouth, and property is put down, this medicine is mild, has effect of eliminating dampness by diuresis diuresis, stomach function regulating spleen invigorating, spirit heart and tranquilizing mind, is widely used in clinical treatment and life enhancement.There are some researches show, pachyman can resisting fatigue, improve the activity of superoxide dismutase (SOD), reduce malonaldehyde (MDA) content, thus slow down aging；The experimentation of Yu Ling etc. shows, Poria can improve hydroxyproline in skin content and can delay skin aging.Below all illustrate that Poria has effect anti-ageing, life lengthening, suitably takes the good health and a long life being conducive to middle-aged and elderly people, and can beauty and skin care.

Radix Glycyrrhizae: sweet, flat.GUIXIN, lung, spleen, stomach warp.Invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.Mudanjiang Medical College biology laboratory Dong Kai has carried out the research of " Radix Glycyrrhizae anti-aging effects ", and research confirms, liquorice beverage decoct can significantly improve SOD activity in mouse aging thymus, hence it is evident that reduces MDA content.Illustrate that the drawing property change of moving back of mouse aging thymocyte cell is had improvement result by Radix Glycyrrhizae.

In sum, a kind of antioxidation of the present invention, defying age have black tea composition and preparation method, give the solution sub-health population method at slow down aging and excess syndrome example with brand-new theory and visual angle, and have significant effect.

Accordingly, a kind of antioxidation of the present invention, defying age have black tea composition and preparation method to also proposed the formula consistent with the present invention, preparation method and embodiment while completely elaborating above-mentioned theory and having quoted substantial amounts of scientific research experimental result as proof.

Embodiment

The selection of embodiment 1 raw material

In the present invention, the selection of raw material has its special feature and GENE SOURCES.

In the present invention, the selection of a kind of primary raw material tea is one of principal element indispensable in the most key, prescription compatibility.Therefore, in the present invention, have selected the daye tea raw material originating in Ya Erhu.

Embodiment 2: the making of raw dark green tea.

The invention provides a kind of manufacturing technology rule producing raw dark green tea.It is science, is again leave over, pass on the tea making marrow got off in tradition tea-manufacturing technology.

As the first step, select " all sorts of flowers condensation " tea kind source, in stepping in setting up ANHUA HEI CHA quality control system, go out the first step of key.

Present invention also offers ANHUA HEI CHA raw dark green tea manufacturing technology scheme:

Postfermented tea product be divided into sky point, tribute point, raw brick sharp, black, ornamental slab for paving the floor, FUZHUAN etc. several.Its quality of oolong tea generally requires profile bar rope convolution and straight, the black profit of color and luster, except there is pure tea perfume (or spice), and must also with special Colophonium smoke.In endoplasm requirement, it requires that soup color is orange, and fragrance is pure, and flavour is mellow, and at the bottom of leaf, Huang is unbuttoned or divest one's upper garment.First process processed includes completing, kneads, wet heap, rub again, five operations such as dry.According to the raw dark green tea of above-mentioned explained hereafter processing and fabricating, it is stored in special wooden tea storehouse standby.

Embodiment 3: the preparation (1) of integration of edible and medicinal herbs class article extract

Take the Radix Ginseng Rubra of aforesaid 30～90 weight portions, the Radix Astragali of 60～120 weight portions, the Radix Rehmanniae of 100～360 weight portions, baogan medlar of 70～150 weight portions, the Radix Ophiopogonis of 60～120 weight portions, the Radix Asparagi of 60～120 weight portions, the Rhizoma Polygonati of 70～150 weight portions, the Rhizoma dioscoreae of 70～150 weight portions, the Fructus Corni of 70～150 weight portions, the Herba Epimedii of 80～180 weight portions, the Radix Rhodiolae of 60～120 weight portions, the Flos Rosae Rugosae of 50～90 weight portions, the Cordyceps mycelium of 50～90 weight portions, the Poria of 30～70 weight portions, the Radix Glycyrrhizae of 20～50 weight portions.

Embodiment 4: the preparation (2) of integration of edible and medicinal herbs class article superfine powder

Take the Radix Ginseng Rubra of aforesaid 30～90 weight portions, the Radix Astragali of 60～120 weight portions, the Radix Rehmanniae of 100～360 weight portions, baogan medlar of 70～150 weight portions, the Radix Ophiopogonis of 60～120 weight portions, the Radix Asparagi of 60～120 weight portions, the Rhizoma Polygonati of 70～150 weight portions, the Rhizoma dioscoreae of 70～150 weight portions, the Fructus Corni of 70～150 weight portions, the Herba Epimedii of 80～180 weight portions, the Radix Rhodiolae of 60～120 weight portions, the Flos Rosae Rugosae of 50～90 weight portions, the Cordyceps mycelium of 50～90 weight portions, the Poria of 30～70 weight portions, the Radix Glycyrrhizae of 20～50 weight portions, put in super micron mill, the superfine powder being crushed to average particle size particle size 0.3～2 μm is standby.

Embodiment 5: compacting Fu-brick tea

1, the mixture of compositions

Take two grades of raw dark green tea 30～60 kilograms, four, each 15～20 kilograms of Pyatyi raw dark green tea, add 7～15 kilograms of extract powders or superfine powder, mixing, spray wine proper amount of clear water, profit leaching entered next procedure according to the processing technology of Fu-brick tea after 30 minutes.It is pressed into 100 Fu-brick tea.

2, tea compacting is steamed:

3, dry in the sun sizing:

4, dry grow dim:

5, finished product packing:

Especially should special suggestion, make FUZHUAN time, present invention particularly provides following important supplement technical scheme:

1., the moisture impact on quality of growing dim

From table 1 it follows that in dry season, when adobe water content is when 15%, without the growth of Eurotium cristatum, say, that can not normally grow dim.When moisture content reaches 22%, grow dim good.When moisture content reaches 28%, grow dim steady quality.In high temperature, high humidity season, when moisture content reaches 20%, it grows dim well；Moisture content quality of growing dim when reaching 22% is the most stable.

Situation of growing dim during table 1 Fu-brick tea adobe different moisture content

Green brick moisture content is one of essential condition of growing dim of Fu-brick tea.The nutrition that Eurotium cristatum is by absorbing in Folium Camelliae sinensis is just developable, the absorption of nutrient substance and decompose polyphenol compound, carbohydrate sugar composition, is all be medium by water.Traditional viewpoint and about thinking in paper that the moisture content that Fu-brick tea grows dim is 28%, situation and the related data obtained production practices tested in recent years from us all prove, the moisture content of Fu-brick tea adobe should carry out effective regulation and control respectively and be only that promotion Fu-brick tea is normal, health grows dim correct effective means according to the concrete condition of Various Seasonal.In general, under hot and humid gas condition, moisture content should be more lower, namely should control between 20～22%.And in dry season, then should suitably moisturize content, its moisture content can be suitably controlled in 22～25% and be advisable.Furthermore, it should also be noted that suitably the problem that moisture content is not enough can be made up by the prolongation time of growing dim.

The angle produced from whole Fu-brick tea considers, best control rate is that, during high-temperature high humidity season, the moisture content of its adobe should control 20%；Dry season should control when 22% ideal.So can reach good purpose of growing dim, the Fu-brick tea time in drying room can be shortened again, be beneficial to reduce production cost, improve yield.

2., the temperature impact on growing dim

The optimum temperature of the most of fungus of nature is 25～37%.Relevant experimental study shows: the optimum temperature of Eurotium cristatum growth is at about 28 DEG C.Can be seen that (table 2) from temperature test result, growing dim of Fu-brick tea is had effect two kinds different by temperature.Under natural temperature, the subject range of Eurotium cristatum is relatively broad, and the temperature limitations grown dim is also just less.And control, under environment, to grow dim when drying room temperature reaches more than 25 DEG C just relatively difficult in artificial self the heating of drying room.This is because, when drying room conducting self-heating temperature raising, the air humidity in drying room reduces, and accelerates the moisture loss in adobe；When in drying room, the temperature of conducting self-heating reaches 30 DEG C, therefore the moisture in adobe will scatter and disappear too fast, and moisture does not reach the requirement grown dim, thus just seldom sees JINHUA normal growth and grow.If sprinkled water in drying room, requirement of growing dim still still can be reached.Under field conditions (factors), optimum temperature of growing dim is at about 25 DEG C；When natural low temperature, optimum temperature of growing dim is at about 15 DEG C.Having certain humidity in air, add that the water evaporation quantity in brick tea tea base is few, this makes the growth promoter for Eurotium cristatum provide the moisture condition of abundance.When Organic substance in Folium Camelliae sinensis, particularly carbohydrate carry out oxidation heat liberation under the effect of microorganism, the temperature in Fu-brick tea base can be caused higher than extraneous ambient temperature.And this exothermic reaction carries out in a kind of situation slowly, if it is possible to suitably extend and grow dim the time, it is also possible to reach the requirement grown dim.When ambient temperature is higher, due to the microclimate conditions effect in drying room, cushion the unfavorable factor that Eurotium cristatum is grown by high temperature.Therefore, as long as can accomplish when summer high temperature to ensure that drying room is ventilated, even temperature is up to 38 DEG C, grows dim and also can complete in a short time.Required time of growing dim generally only needs about 7 days, and quality of growing dim is good.

Under table 2 condition of different temperatures, Fu-brick tea grows dim situation

3., containing the impact on growing dim of the stalk amount

Containing stalk amount number and tenderness affect the growth promoter of Eurotium cristatum, the quality of impact " JINHUA " and quantity to a great extent.Result of the test is in Table 3.

Table 3 difference amount containing stalk is grown dim situation

From table 3 it is known that Fu-brick tea containing stalk amount when 30%, it grows dim best in quality, is difficult to grow dim during lower than 5%.

The tea bar of certain tenderness, its chemical composition except Polyphenols, caffeine, protein content relatively tender leaf less except, the content of the carbohydrate such as saccharide, starch based is higher.And carbohydrate is the basic substance of Eurotium cristatum growth promoter, therefore, the stalky tea of certain tenderness is conducive to growing dim.We produce with test in it is often found that, have flavous " JINHUA " in a large number around stalky tea or camellia oleosa seed.On the other hand, a number of stalky tea can improve the venting capability in adobe, is also beneficial to the growth of Eurotium cristatum, is conducive to growing dim of Fu-brick tea.It should be noted that in Fu-brick tea production process, the too high quality that also can affect Fu-brick tea of the amount containing stalk, therefore, must note controlling below 20% containing stalk amount.

4., the impact of the adobe elasticity of Fu-brick tea with compare

Fu-brick tea generally all uses the wooden model of certain specification to make product compressing in the process produced.The adobe length and width shaped all has certain value.And the performance of the thickness of adobe substantially product elasticity.

From the adobe of different-thickness grow dim result of the test (table 4) it can be seen that when adobe only has 3cm Fu-brick tea can not grow dim, when reaching 6cm, Fu-brick tea goes mouldy, the only black mould generation of bacterium, and this is the performance of rotten Fu-brick tea.Only when its thickness is 4～5cm, its quality grown dim is the best.Such as following table:

The impact that Fu-brick tea is grown dim by table 4 adobe thickness

The preparation method of the present invention is equally applicable to compacting black brick tea, ornamental slab for paving the floor tea, green brick tea；Step on thousand tael tea processed and hundred liang of tea；Make sky point tea, gongjian tea, raw point tea；Also it is equally applicable to make thin slice tea, Tuo tea, Fructus Citri tangerinae FUCHA；Compacting black tea brick tea, green tea brick tea, Ramulus et Folium Mussaendae Pubescentis brick tea；Also it is applicable to produce teabag, tea ointment, instant tea, capsule tea, making containing tablet tea and tea beverage.

In a word, a kind of antioxidation of the present invention, defying age black tea composition, at the formula of the present invention, followed strictly Chinese medicine about the theory of compatibility and clinical practice experience.Accomplish that compatibility is rigorous, exquisite, complement each other, be association of activity and inertia, have the wonderful of reinforcing both QI and YIN, thus being capable of the purpose of antioxidation, defying age, life lengthening after long-term drink to realize the present invention.

In a word, the black tea composition of a kind of antioxidant and anti-aging of the present invention, the good recipe no matter from compatibility, side's medicine composition, or dosage form, be all that potion health care is anti-ageing, eliminating disease and prolong life, can often drink by informal dress, to play the special effect of " playing my heavy illness, precious match Qiongyao ".

Be likely to above embodiments, every those skilled in the art or the personnel relevant to this area to cause change with association, expansion, the mode such as contrast, extend, situation in analogy scope all can be considered occupying the present invention.The above embodiments are only merely the citing to the present invention or proof.It can carry out association or the expansion of wide in range property on this basis, and it can also carry out unconfined according to replicating and recreation based on this.The black tea composition of a kind of antioxidant and anti-aging of the present invention and preparation method have protection equally to not surmounting the principle of scope, method, technology opinion or manufacture, say, that it belongs to protection scope of the present invention.

Claims

1. the black tea composition of an antioxidant and anti-aging is made up of integration of edible and medicinal herbs class article such as ANHUA HEI CHA and Radix Ginseng Rubra, the Radix Astragali, Radix Rehmanniae, baogan medlar, Radix Ophiopogonis, Radix Asparagi, Rhizoma Polygonati, Rhizoma dioscoreae, Fructus Corni, Herba Epimedii, Radix Rhodiolae, Flos Rosae Rugosae, Cordyceps mycelium, Poria, Radix Glycyrrhizaes.

2. the black tea composition of a kind of antioxidant and anti-aging according to claim 1, the selection of raw material has its special feature and GENE SOURCES.In the present invention, select to originate in the daye tea raw material of Ya Erhu.

3. the black tea composition of a kind of antioxidant and anti-aging according to claim 1, the preparation method of the present invention is equally applicable to compacting black brick tea, ornamental slab for paving the floor tea, green brick tea；Step on thousand tael tea processed and hundred liang of tea；Make sky point tea, gongjian tea, raw point tea；Also it is equally applicable to make thin slice tea, Tuo tea, Fructus Citri tangerinae FUCHA；Compacting black tea brick tea, green tea brick tea, Ramulus et Folium Mussaendae Pubescentis brick tea；Also it is applicable to produce teabag, tea ointment, instant tea, capsule tea, making containing tablet tea and tea beverage.

4. the black tea composition of a kind of antioxidant and anti-aging according to claim 1, it is characterised in that: its quality of oolong tea generally requires profile bar rope convolution and straight, the black profit of color and luster, except there is pure tea perfume (or spice), must also with special Colophonium smoke.In endoplasm requirement, it requires that soup color is orange, and fragrance is pure, and flavour is mellow, and at the bottom of leaf, Huang is unbuttoned or divest one's upper garment.First process processed includes completing, kneads, wet heap, rub again, five operations such as dry.According to the raw dark green tea of above-mentioned explained hereafter processing and fabricating, it is stored in special wooden tea storehouse standby.

5. the black tea composition of a kind of antioxidant and anti-aging according to claim 1, it is characterized in that: the weight portion of integration of edible and medicinal herbs article is the Radix Ginseng Rubra of 30～90 weight portions, the Radix Astragali of 60～120 weight portions, the Radix Rehmanniae of 100～360 weight portions, baogan medlar of 70～150 weight portions, the Radix Ophiopogonis of 60～120 weight portions, the Radix Asparagi of 60～120 weight portions, the Rhizoma Polygonati of 70～150 weight portions, the Rhizoma dioscoreae of 70～150 weight portions, the Fructus Corni of 70～150 weight portions, the Herba Epimedii of 80～180 weight portions, the Radix Rhodiolae of 60～120 weight portions, the Flos Rosae Rugosae of 50～90 weight portions, the Cordyceps mycelium of 50～90 weight portions, the Poria of 30～70 weight portions, the Radix Glycyrrhizae of 20～50 weight portions.They can be a kind of or whole, it is preferred that is at least 9 kinds or 11 kinds.

6. the black tea composition of a kind of antioxidant and anti-aging according to claim 1, it is characterised in that: above-mentioned integration of edible and medicinal herbs mixtures of articles puts into extraction pot, and first time adds the pure water of medical material amount 10 times amount, decocts 2 hours；Second time adds the pure water of 8 times amount and decocts 1.5 hours.Merge with upper liquid, filter, be concentrated into relative density 1.12～1.25, standby after spraying drying powder-forming.When producing by above-mentioned raw dark green tea 90%, add and raw dark green tea weight equivalent 10% dry powder, mix in proportion, stand-by.

7. the black tea composition of a kind of antioxidant and anti-aging according to claim 1, it is characterised in that: the preparation method of the present invention is equally applicable to compacting black brick tea, ornamental slab for paving the floor tea, green brick tea；Step on thousand tael tea processed and hundred liang of tea；Make sky point tea, gongjian tea, raw point tea；Also it is equally applicable to make thin slice tea, Tuo tea, Fructus Citri tangerinae FUCHA；Compacting black tea brick tea, green tea brick tea, Ramulus et Folium Mussaendae Pubescentis brick tea；Also it is applicable to produce teabag, tea ointment, instant tea, capsule tea, making containing tablet tea and tea beverage.