CN101321535A - 杂芳香磺酰胺前药 - Google Patents
杂芳香磺酰胺前药 Download PDFInfo
- Publication number
- CN101321535A CN101321535A CNA2006800450153A CN200680045015A CN101321535A CN 101321535 A CN101321535 A CN 101321535A CN A2006800450153 A CNA2006800450153 A CN A2006800450153A CN 200680045015 A CN200680045015 A CN 200680045015A CN 101321535 A CN101321535 A CN 101321535A
- Authority
- CN
- China
- Prior art keywords
- sulfamoyl
- beta
- carboxylate
- triolefins
- female
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
- A61K31/5685—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone having an oxo group in position 17, e.g. androsterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J33/00—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Epidemiology (AREA)
- Gynecology & Obstetrics (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Pregnancy & Childbirth (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102005057421A DE102005057421A1 (de) | 2005-11-30 | 2005-11-30 | Heteroaromatische Sulfonamid-Prodrugs |
DE102005057421.1 | 2005-11-30 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN101321535A true CN101321535A (zh) | 2008-12-10 |
Family
ID=37875507
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNA2006800450153A Pending CN101321535A (zh) | 2005-11-30 | 2006-11-27 | 杂芳香磺酰胺前药 |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP1959964A1 (de) |
JP (1) | JP2009517425A (de) |
KR (1) | KR20080074197A (de) |
CN (1) | CN101321535A (de) |
AU (1) | AU2006319381A1 (de) |
BR (1) | BRPI0619214A2 (de) |
CA (1) | CA2632279A1 (de) |
DE (1) | DE102005057421A1 (de) |
EA (1) | EA200801209A1 (de) |
EC (1) | ECSP088488A (de) |
IL (1) | IL191563A0 (de) |
NO (1) | NO20082916L (de) |
WO (1) | WO2007062875A1 (de) |
ZA (1) | ZA200805660B (de) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101987104A (zh) * | 2009-08-05 | 2011-03-23 | 天津金耀集团有限公司 | 一种杂芳香基氨磺酰基羧酸酯碳酸酐酶抑制剂的眼用组合物 |
CN101987102A (zh) * | 2009-08-05 | 2011-03-23 | 天津金耀集团有限公司 | 一种糖皮质激素杂芳香基氨磺酰基羧酸酯的眼用抗炎组合物 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1593609A (en) * | 1978-01-31 | 1981-07-22 | Christiaens Sa A | Pyridine sulfonamides |
DE10027887A1 (de) * | 2000-05-31 | 2001-12-13 | Jenapharm Gmbh | Verbindungen mit einer Sulfonamidgruppe und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen |
US6355666B1 (en) * | 2000-06-23 | 2002-03-12 | Medinox, Inc. | Protected forms of pharmacologically active agents and uses therefor |
AR053845A1 (es) * | 2005-04-15 | 2007-05-23 | Tibotec Pharm Ltd | 5-tiazolilmetil[(1s,2r)-3-[[(2-amino-6-benzoxazolil)sulfonil)](2-metilpropil)amino]-2-hidroxi-1-(fenilmetil)propil]carbamato como mejorador de farmacos metabolizados por el citocromo p450 |
-
2005
- 2005-11-30 DE DE102005057421A patent/DE102005057421A1/de not_active Ceased
-
2006
- 2006-11-27 KR KR1020087015778A patent/KR20080074197A/ko not_active Application Discontinuation
- 2006-11-27 BR BRPI0619214-9A patent/BRPI0619214A2/pt not_active Application Discontinuation
- 2006-11-27 CA CA002632279A patent/CA2632279A1/en not_active Abandoned
- 2006-11-27 CN CNA2006800450153A patent/CN101321535A/zh active Pending
- 2006-11-27 EA EA200801209A patent/EA200801209A1/ru unknown
- 2006-11-27 JP JP2008542679A patent/JP2009517425A/ja active Pending
- 2006-11-27 AU AU2006319381A patent/AU2006319381A1/en not_active Abandoned
- 2006-11-27 WO PCT/EP2006/011727 patent/WO2007062875A1/de active Application Filing
- 2006-11-27 EP EP06829355A patent/EP1959964A1/de not_active Withdrawn
-
2008
- 2008-05-20 IL IL191563A patent/IL191563A0/en unknown
- 2008-05-30 EC EC2008008488A patent/ECSP088488A/es unknown
- 2008-06-27 ZA ZA200805660A patent/ZA200805660B/xx unknown
- 2008-06-27 NO NO20082916A patent/NO20082916L/no not_active Application Discontinuation
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101987104A (zh) * | 2009-08-05 | 2011-03-23 | 天津金耀集团有限公司 | 一种杂芳香基氨磺酰基羧酸酯碳酸酐酶抑制剂的眼用组合物 |
CN101987102A (zh) * | 2009-08-05 | 2011-03-23 | 天津金耀集团有限公司 | 一种糖皮质激素杂芳香基氨磺酰基羧酸酯的眼用抗炎组合物 |
Also Published As
Publication number | Publication date |
---|---|
DE102005057421A1 (de) | 2007-05-31 |
CA2632279A1 (en) | 2007-06-07 |
WO2007062875B1 (de) | 2007-08-09 |
EA200801209A1 (ru) | 2008-12-30 |
BRPI0619214A2 (pt) | 2011-09-20 |
NO20082916L (no) | 2008-06-27 |
WO2007062875A1 (de) | 2007-06-07 |
JP2009517425A (ja) | 2009-04-30 |
ECSP088488A (es) | 2008-06-30 |
IL191563A0 (en) | 2009-08-03 |
AU2006319381A1 (en) | 2007-06-07 |
EP1959964A1 (de) | 2008-08-27 |
ZA200805660B (en) | 2009-11-25 |
KR20080074197A (ko) | 2008-08-12 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN1315867C (zh) | 作为抗炎剂的17β-硫代羧酸酯17α-芳基羰氧基雄甾烷衍生物 | |
CN100384830C (zh) | 环黄芪醇类衍生物以及用途 | |
CN1052155C (zh) | 含新的甾族化合物的药物组合物的制法 | |
JP2003517436A (ja) | 19−ノルアンドロスタン系列の14,15−シクロプロパノステロイド、その製造法および該化合物を含有する製薬学的調製剤 | |
EA020488B1 (ru) | Производные пурина или деазапурина для применения при лечении вирусных инфекций и других заболеваний | |
CN105985396A (zh) | 氘代鹅去氧胆酸衍生物以及包含该化合物的药物组合物 | |
SA99200688A (ar) | أرابينوسيدات البيورين المستبدلة واستخدامها في علاج الإصابة بمرض فيروس الحمض النووي (dna) | |
CN103282358A (zh) | C-17-杂芳基类固醇化合物作为cyp11b、cyp17 及/或cyp21 抑制剂 | |
CZ302513B6 (cs) | Steroid, farmaceutická kompozice tento steroid obsahující, zpusob prípravy tohoto steroidu a meziprodukty pro tento zpusob | |
CN102834405A (zh) | 孕酮受体拮抗剂 | |
JP2002518514A (ja) | テストステロン誘導体 | |
US10246481B2 (en) | Bile acid derivatives and methods for synthesis and use | |
CN101321535A (zh) | 杂芳香磺酰胺前药 | |
CN101316858A (zh) | 氨磺酰基磺酸酯前药 | |
JP3377856B2 (ja) | 骨吸収抑制・骨形成促進化合物 | |
US20070135399A1 (en) | Heteroaromatic sulphonamide prodrugs | |
Sharma et al. | Synthesis and anti-HIV activity of prodrugs of azidothymidine | |
CN104995189B (zh) | 丙型肝炎药物的晶型及其制备方法、其药物组合物和用途 | |
CZ20021589A3 (cs) | Deriváty ß-D-5-thioxylózy, způsob jejich přípravy a jejich terapeutické pouľití | |
KR100472303B1 (ko) | 결장표적성 프로드럭으로서의 코티코스테로이드21-설페이트 소듐 유도체 | |
CN103755767B (zh) | Cddo乙基酯的多晶型物及其用途 | |
CN104497086B (zh) | 雄甾-3β,5α,6β,19-四醇及其制备方法与应用 | |
JP2002030073A (ja) | 4−(3−(4−モルホリノブチリルアミノ)フェニル)−2h−フタラジン−1−オン・メタンスルホン酸塩・1水和物およびその製造方法。 | |
CN114957375A (zh) | 一种薯蓣皂苷元季磷盐类衍生物及其制备方法和医药用途 | |
TW213922B (de) |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
WD01 | Invention patent application deemed withdrawn after publication |
Open date: 20081210 |