CN101313731B - Anti-stress feedstuff additive - Google Patents
Anti-stress feedstuff additive Download PDFInfo
- Publication number
- CN101313731B CN101313731B CN200810116768XA CN200810116768A CN101313731B CN 101313731 B CN101313731 B CN 101313731B CN 200810116768X A CN200810116768X A CN 200810116768XA CN 200810116768 A CN200810116768 A CN 200810116768A CN 101313731 B CN101313731 B CN 101313731B
- Authority
- CN
- China
- Prior art keywords
- percent
- stress
- feed additives
- vitamin
- test
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 230000002180 anti-stress Effects 0.000 title claims abstract description 23
- 239000000654 additive Substances 0.000 title description 2
- 230000000996 additive effect Effects 0.000 title description 2
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims abstract description 24
- 239000000463 material Substances 0.000 claims abstract description 22
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims abstract description 20
- XLOMVQKBTHCTTD-UHFFFAOYSA-N Zinc monoxide Chemical compound [Zn]=O XLOMVQKBTHCTTD-UHFFFAOYSA-N 0.000 claims abstract description 18
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 claims abstract description 15
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 claims abstract description 12
- 229930003268 Vitamin C Natural products 0.000 claims abstract description 12
- 235000019154 vitamin C Nutrition 0.000 claims abstract description 12
- 239000011718 vitamin C Substances 0.000 claims abstract description 12
- 239000004475 Arginine Substances 0.000 claims abstract description 10
- 241001061264 Astragalus Species 0.000 claims abstract description 10
- QIVBCDIJIAJPQS-VIFPVBQESA-N L-tryptophane Chemical compound C1=CC=C2C(C[C@H](N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-VIFPVBQESA-N 0.000 claims abstract description 10
- QIVBCDIJIAJPQS-UHFFFAOYSA-N Tryptophan Natural products C1=CC=C2C(CC(N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-UHFFFAOYSA-N 0.000 claims abstract description 10
- 229930003427 Vitamin E Natural products 0.000 claims abstract description 10
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 claims abstract description 10
- 235000006533 astragalus Nutrition 0.000 claims abstract description 10
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims abstract description 10
- 210000004233 talus Anatomy 0.000 claims abstract description 10
- 235000019165 vitamin E Nutrition 0.000 claims abstract description 10
- 229940046009 vitamin E Drugs 0.000 claims abstract description 10
- 239000011709 vitamin E Substances 0.000 claims abstract description 10
- 229940046374 chromium picolinate Drugs 0.000 claims abstract description 9
- GJYSUGXFENSLOO-UHFFFAOYSA-N chromium;pyridine-2-carboxylic acid Chemical compound [Cr].OC(=O)C1=CC=CC=N1.OC(=O)C1=CC=CC=N1.OC(=O)C1=CC=CC=N1 GJYSUGXFENSLOO-UHFFFAOYSA-N 0.000 claims abstract description 9
- 239000011787 zinc oxide Substances 0.000 claims abstract description 9
- 239000004151 Calcium iodate Substances 0.000 claims abstract description 8
- UHWJJLGTKIWIJO-UHFFFAOYSA-L calcium iodate Chemical compound [Ca+2].[O-]I(=O)=O.[O-]I(=O)=O UHWJJLGTKIWIJO-UHFFFAOYSA-L 0.000 claims abstract description 8
- 235000019390 calcium iodate Nutrition 0.000 claims abstract description 8
- BVTBRVFYZUCAKH-UHFFFAOYSA-L disodium selenite Chemical compound [Na+].[Na+].[O-][Se]([O-])=O BVTBRVFYZUCAKH-UHFFFAOYSA-L 0.000 claims abstract description 8
- 229910000402 monopotassium phosphate Inorganic materials 0.000 claims abstract description 8
- 235000019796 monopotassium phosphate Nutrition 0.000 claims abstract description 8
- PJNZPQUBCPKICU-UHFFFAOYSA-N phosphoric acid;potassium Chemical compound [K].OP(O)(O)=O PJNZPQUBCPKICU-UHFFFAOYSA-N 0.000 claims abstract description 8
- 229960001471 sodium selenite Drugs 0.000 claims abstract description 8
- 239000011781 sodium selenite Substances 0.000 claims abstract description 8
- 235000015921 sodium selenite Nutrition 0.000 claims abstract description 8
- 229910052938 sodium sulfate Inorganic materials 0.000 claims abstract description 8
- 235000011152 sodium sulphate Nutrition 0.000 claims abstract description 8
- 241000205585 Aquilegia canadensis Species 0.000 claims abstract description 7
- IPQKDIRUZHOIOM-UHFFFAOYSA-N Oroxin A Natural products OC1C(O)C(O)C(CO)OC1OC(C(=C1O)O)=CC2=C1C(=O)C=C(C=1C=CC=CC=1)O2 IPQKDIRUZHOIOM-UHFFFAOYSA-N 0.000 claims description 9
- IKIIZLYTISPENI-ZFORQUDYSA-N baicalin Chemical compound O1[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1OC(C(=C1O)O)=CC2=C1C(=O)C=C(C=1C=CC=CC=1)O2 IKIIZLYTISPENI-ZFORQUDYSA-N 0.000 claims description 9
- 229960003321 baicalin Drugs 0.000 claims description 9
- AQHDANHUMGXSJZ-UHFFFAOYSA-N baicalin Natural products OC1C(O)C(C(O)CO)OC1OC(C(=C1O)O)=CC2=C1C(=O)C=C(C=1C=CC=CC=1)O2 AQHDANHUMGXSJZ-UHFFFAOYSA-N 0.000 claims description 9
- 239000001525 mentha piperita l. herb oil Substances 0.000 claims description 9
- 235000019477 peppermint oil Nutrition 0.000 claims description 9
- 229920002472 Starch Polymers 0.000 claims description 4
- 239000000470 constituent Substances 0.000 claims description 4
- 239000000843 powder Substances 0.000 claims description 4
- 239000008107 starch Substances 0.000 claims description 4
- 235000019698 starch Nutrition 0.000 claims description 4
- 101710184005 Glutaminase 2 Proteins 0.000 claims description 3
- 102100025961 Glutaminase liver isoform, mitochondrial Human genes 0.000 claims description 3
- 101710184006 Glutaminase 1 Proteins 0.000 claims description 2
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 claims description 2
- 229930006000 Sucrose Natural products 0.000 claims description 2
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims description 2
- 229910021536 Zeolite Inorganic materials 0.000 claims description 2
- HNPSIPDUKPIQMN-UHFFFAOYSA-N dioxosilane;oxo(oxoalumanyloxy)alumane Chemical compound O=[Si]=O.O=[Al]O[Al]=O HNPSIPDUKPIQMN-UHFFFAOYSA-N 0.000 claims description 2
- 239000008101 lactose Substances 0.000 claims description 2
- 239000005720 sucrose Substances 0.000 claims description 2
- 239000010457 zeolite Substances 0.000 claims description 2
- 239000000203 mixture Substances 0.000 abstract description 15
- 241001465754 Metazoa Species 0.000 abstract description 10
- 239000003674 animal food additive Substances 0.000 abstract description 8
- 230000008642 heat stress Effects 0.000 abstract description 6
- 244000144977 poultry Species 0.000 abstract description 5
- 230000008645 cold stress Effects 0.000 abstract description 4
- 230000018044 dehydration Effects 0.000 abstract description 3
- 238000006297 dehydration reaction Methods 0.000 abstract description 3
- 239000003792 electrolyte Substances 0.000 abstract description 3
- 239000000284 extract Substances 0.000 abstract description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract description 3
- 244000246386 Mentha pulegium Species 0.000 abstract description 2
- 235000016257 Mentha pulegium Nutrition 0.000 abstract description 2
- 230000008901 benefit Effects 0.000 abstract description 2
- 235000008418 Hedeoma Nutrition 0.000 abstract 1
- 229930182478 glucoside Natural products 0.000 abstract 1
- 150000008131 glucosides Chemical class 0.000 abstract 1
- ZDXPYRJPNDTMRX-UHFFFAOYSA-N glutamine Natural products OC(=O)C(N)CCC(N)=O ZDXPYRJPNDTMRX-UHFFFAOYSA-N 0.000 abstract 1
- 150000004676 glycans Chemical class 0.000 abstract 1
- 230000003204 osmotic effect Effects 0.000 abstract 1
- 229920001282 polysaccharide Polymers 0.000 abstract 1
- 239000005017 polysaccharide Substances 0.000 abstract 1
- 230000003014 reinforcing effect Effects 0.000 abstract 1
- 238000012360 testing method Methods 0.000 description 54
- 241000251468 Actinopterygii Species 0.000 description 19
- 230000035882 stress Effects 0.000 description 17
- 230000001186 cumulative effect Effects 0.000 description 11
- 230000035611 feeding Effects 0.000 description 9
- 239000012467 final product Substances 0.000 description 9
- 230000006806 disease prevention Effects 0.000 description 8
- 230000000694 effects Effects 0.000 description 8
- 238000007726 management method Methods 0.000 description 8
- 238000000034 method Methods 0.000 description 8
- 241000283690 Bos taurus Species 0.000 description 7
- 241000276701 Oreochromis mossambicus Species 0.000 description 7
- 235000013336 milk Nutrition 0.000 description 7
- 239000008267 milk Substances 0.000 description 7
- 210000004080 milk Anatomy 0.000 description 7
- 239000000126 substance Substances 0.000 description 7
- 241000282898 Sus scrofa Species 0.000 description 6
- 240000008042 Zea mays Species 0.000 description 6
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 6
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 6
- 150000001413 amino acids Chemical class 0.000 description 6
- 229910021529 ammonia Inorganic materials 0.000 description 6
- 235000005822 corn Nutrition 0.000 description 6
- 238000002360 preparation method Methods 0.000 description 6
- 238000005303 weighing Methods 0.000 description 6
- 230000000052 comparative effect Effects 0.000 description 5
- 239000003814 drug Substances 0.000 description 5
- 239000000047 product Substances 0.000 description 5
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 4
- 108010073324 Glutaminase Proteins 0.000 description 4
- 102000009127 Glutaminase Human genes 0.000 description 4
- ODKSFYDXXFIFQN-BYPYZUCNSA-P L-argininium(2+) Chemical compound NC(=[NH2+])NCCC[C@H]([NH3+])C(O)=O ODKSFYDXXFIFQN-BYPYZUCNSA-P 0.000 description 4
- 239000011575 calcium Substances 0.000 description 4
- 238000006243 chemical reaction Methods 0.000 description 4
- 229910052500 inorganic mineral Inorganic materials 0.000 description 4
- 239000011707 mineral Substances 0.000 description 4
- 235000010755 mineral Nutrition 0.000 description 4
- 108090000623 proteins and genes Proteins 0.000 description 4
- 102000004169 proteins and genes Human genes 0.000 description 4
- 241000287828 Gallus gallus Species 0.000 description 3
- 244000046052 Phaseolus vulgaris Species 0.000 description 3
- 235000010627 Phaseolus vulgaris Nutrition 0.000 description 3
- 235000019742 Vitamins premix Nutrition 0.000 description 3
- 229960003121 arginine Drugs 0.000 description 3
- 229940079593 drug Drugs 0.000 description 3
- 230000003203 everyday effect Effects 0.000 description 3
- 235000013312 flour Nutrition 0.000 description 3
- 229910001410 inorganic ion Inorganic materials 0.000 description 3
- 238000012545 processing Methods 0.000 description 3
- 210000002966 serum Anatomy 0.000 description 3
- 239000004575 stone Substances 0.000 description 3
- 229960004799 tryptophan Drugs 0.000 description 3
- 229960001296 zinc oxide Drugs 0.000 description 3
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 2
- 241000196324 Embryophyta Species 0.000 description 2
- 239000009636 Huang Qi Substances 0.000 description 2
- 208000029422 Hypernatremia Diseases 0.000 description 2
- 240000007594 Oryza sativa Species 0.000 description 2
- 235000007164 Oryza sativa Nutrition 0.000 description 2
- 241000282887 Suidae Species 0.000 description 2
- 230000003044 adaptive effect Effects 0.000 description 2
- 230000000840 anti-viral effect Effects 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 238000009395 breeding Methods 0.000 description 2
- 230000001488 breeding effect Effects 0.000 description 2
- 229910052791 calcium Inorganic materials 0.000 description 2
- FUFJGUQYACFECW-UHFFFAOYSA-L calcium hydrogenphosphate Chemical compound [Ca+2].OP([O-])([O-])=O FUFJGUQYACFECW-UHFFFAOYSA-L 0.000 description 2
- 235000012343 cottonseed oil Nutrition 0.000 description 2
- 235000019700 dicalcium phosphate Nutrition 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 210000003608 fece Anatomy 0.000 description 2
- 241000411851 herbal medicine Species 0.000 description 2
- 244000144980 herd Species 0.000 description 2
- 230000036039 immunity Effects 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 231100000567 intoxicating Toxicity 0.000 description 2
- 230000002673 intoxicating effect Effects 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 235000016709 nutrition Nutrition 0.000 description 2
- 239000000575 pesticide Substances 0.000 description 2
- 239000002994 raw material Substances 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 235000009566 rice Nutrition 0.000 description 2
- 150000003839 salts Chemical class 0.000 description 2
- 239000011734 sodium Substances 0.000 description 2
- 238000010998 test method Methods 0.000 description 2
- 229940126680 traditional chinese medicines Drugs 0.000 description 2
- 229930003231 vitamin Natural products 0.000 description 2
- 235000013343 vitamin Nutrition 0.000 description 2
- 239000011782 vitamin Substances 0.000 description 2
- 229940088594 vitamin Drugs 0.000 description 2
- 206010000117 Abnormal behaviour Diseases 0.000 description 1
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 description 1
- 241000132012 Atractylodes Species 0.000 description 1
- 240000002791 Brassica napus Species 0.000 description 1
- 235000004977 Brassica sinapistrum Nutrition 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
- VYZAMTAEIAYCRO-UHFFFAOYSA-N Chromium Chemical compound [Cr] VYZAMTAEIAYCRO-UHFFFAOYSA-N 0.000 description 1
- 208000035473 Communicable disease Diseases 0.000 description 1
- 101710089042 Demethyl-4-deoxygadusol synthase Proteins 0.000 description 1
- 235000019733 Fish meal Nutrition 0.000 description 1
- 206010020597 Hyperchloraemia Diseases 0.000 description 1
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 description 1
- 235000004357 Mentha x piperita Nutrition 0.000 description 1
- 208000008238 Muscle Spasticity Diseases 0.000 description 1
- 231100000678 Mycotoxin Toxicity 0.000 description 1
- 244000197580 Poria cocos Species 0.000 description 1
- 235000008599 Poria cocos Nutrition 0.000 description 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
- 206010037660 Pyrexia Diseases 0.000 description 1
- AYFVYJQAPQTCCC-UHFFFAOYSA-N Threonine Natural products CC(O)C(N)C(O)=O AYFVYJQAPQTCCC-UHFFFAOYSA-N 0.000 description 1
- 239000004473 Threonine Substances 0.000 description 1
- LEHOTFFKMJEONL-UHFFFAOYSA-N Uric Acid Chemical compound N1C(=O)NC(=O)C2=C1NC(=O)N2 LEHOTFFKMJEONL-UHFFFAOYSA-N 0.000 description 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 1
- 239000003905 agrochemical Substances 0.000 description 1
- 235000001014 amino acid Nutrition 0.000 description 1
- 230000008485 antagonism Effects 0.000 description 1
- 230000002155 anti-virotic effect Effects 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 235000006708 antioxidants Nutrition 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 230000037396 body weight Effects 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 229910052804 chromium Inorganic materials 0.000 description 1
- 239000011651 chromium Substances 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 238000012258 culturing Methods 0.000 description 1
- 235000013365 dairy product Nutrition 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 210000003746 feather Anatomy 0.000 description 1
- 235000021323 fish oil Nutrition 0.000 description 1
- 239000004467 fishmeal Substances 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 230000003370 grooming effect Effects 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 235000001050 hortel pimenta Nutrition 0.000 description 1
- 230000002706 hydrostatic effect Effects 0.000 description 1
- 230000000396 hypokalemic effect Effects 0.000 description 1
- 230000001900 immune effect Effects 0.000 description 1
- 230000036737 immune function Effects 0.000 description 1
- 238000011081 inoculation Methods 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 244000144972 livestock Species 0.000 description 1
- 235000012054 meals Nutrition 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 229930182817 methionine Natural products 0.000 description 1
- 235000013379 molasses Nutrition 0.000 description 1
- 239000002636 mycotoxin Substances 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 230000035479 physiological effects, processes and functions Effects 0.000 description 1
- 238000011020 pilot scale process Methods 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 239000002574 poison Substances 0.000 description 1
- 231100000572 poisoning Toxicity 0.000 description 1
- 230000000607 poisoning effect Effects 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 208000018198 spasticity Diseases 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 230000032258 transport Effects 0.000 description 1
- 229960005486 vaccine Drugs 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
- 235000015099 wheat brans Nutrition 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
Landscapes
- Fodder In General (AREA)
Abstract
The invention discloses anti-stress feed additives. The compositions of the anti-stress feed additives are: 15 to 30 percent of astragalus polysaccharides, 15 to 30 percent of radix scutellariae glucoside, 10 to 20 percent of pennyroyal wrappage, 10 to 20 percent of honeysuckle extract, 0.5 to 5 percent of vitamin C, 0.5 to 5 percent of vitamin E, 0.001 to 0.02 percent of chromium picolinate, 0.05 to 0.3 percent of zinc oxide, 0.1 to 1 percent of arginine, 1 to 5 percent of tryptophan, 1 to 5 percent of glutamine, 1 to 5 percent of sodium sulfate, 1 to 3 percent of calcium iodate, 1 to 3 percent of sodium selenite, 1 to 3 percent of potassium dihydrogen phosphate, the balance being auxiliary materials. The anti-stress feed additives are added into poultry feed according to the ratio of 0.1 to 0.3 percent. The anti-stress feed additives have the advantages that: firstly, the anti-stress feed additives can reinforce the anti-stress capability of poultry, and are particularly suitable for reinforcing the cold stress capability and the heat stress capability; secondly, the anti-stress feed additives can quickly replenish electrolyte loss caused by dehydration, and quickly recover the osmotic pressure of cells and adjust the acid-base balance in the body; and thirdly, the anti-stress feed additives can reinforce the anti-positioning capability of water bodies of the aquatic animals.
Description
Technical field
The invention belongs to feed addictive, relate in particular to a kind of anti-stress feed addictive.
Background technology
Stress be meant that animal population to external world or the inner various summations that stimulate very much the nonspecific response reaction that is produced; These stimulate very much can refer to (Selye such as variations in temperature, ionising radiation, direct stimulation, overtired, infection and poisoning; 1936,138:36).
With the pure natural Chinese herbal medicine as feed addictive; Have and reduce animal stress reaction, diseases prevention, cure the disease, keep healthy, promote effect such as growth, as patent " a kind of antivirus defervescent and preparation method thereof " (patent No.: ZL03801243.X) disclose a kind of with yellow Cen, honeysuckle, peppermint be composition antiviral, bring down a fever, the preparation of enhance immunity power; (patent No.: ZL200410043809.9) disclose a kind of is the anti-heat stress feed additive of main component with the Radix Astragali, Poria cocos, Radix Glycyrrhizae, the bighead atractylodes rhizome to patent " natural plant anti-stress feed addictive "; Patent " a kind of astruganus root medicinal preparation and preparation method thereof the " (patent No.: ZL200610087236.9) disclose the Radix Astragali at enhance immunity, tonifying Qi and anti-stress effect.
Stress also can cause protein and amino acid whose dysbolism; Destroy acid-base balance in the body; And in animal product, produce harmful substance; Be utilized in the feed and add vitamin and amino acid etc. and can address this problem, (application number: 200410012364.8) disclosing a kind of is the remover that prevents harmful substance such as agricultural chemicals, antibiotic in the animal and plant body of eliminating of one of composition with amino acid like " a kind of pesticide herd product harmful substance remover and application thereof "; " a kind of vitamin C and arginic composition and application thereof " (patent No.: ZL03150280.6) disclose a kind of the combination and can improve immune, anti-oxidant and antiviral composition with vitamin C and arginine; " animal brain extract and improve the COF composition of psychological stress adaptive capacity " (patent No.: ZL200410020306.X) disclosing a kind of is composition with vitamin C, vitamin E, glutaminase, tryptophan, chromium, zinc, can effectively improve stress adaptive capacity composition.
But adding Chinese herbal and crude drugs preparations, single use can not improve the protein and the amino acid whose dysbolism that stress cause; Can not keep acid-base balance in the body; Therefore can not eliminate the harmful substance of pesticide herd product, need a kind ofly can reduce stress reaction, can improve simultaneously by stress caused protein and the feed addictive of amino acid whose dysbolism etc. again.
Summary of the invention
The object of the invention is to provide a kind of animal body anti-stress ability that improves, and improves the anti-stress feed addictive of animal product quality.
Technical scheme of the present invention is:
A kind of anti-stress feed addictive; Its constituent and percentage by weight are: astragalus polyose 15～30%, baicalin 15～30%, peppermint oil wrappage 10～20%, Honegsukle flower P.E 10～20%, vitamin C 0.5～5%, vitamin E 0.5～5%, chromium picolinate 0.001～0.02%, zinc oxide 0.05～0.3%, arginine 0.1～1%, tryptophan 1～5%, glutaminase 1～5%, sodium sulphate 1～5%, calcium iodate 1～3%, sodium selenite 1～3%, potassium dihydrogen phosphate 1～3%, surplus are acceptable accessories.
The percentage by weight of constituent is preferably described in the above-mentioned feed addictive: astragalus polyose 25%, baicalin 25%, peppermint oil wrappage 15%, Honegsukle flower P.E 15%, vitamin C 3%, vitamin E 3%, chromium picolinate 0.015%, zinc oxide 0.18%, arginine 0.8%, tryptophan 3%, glutaminase 2%, sodium sulphate 2%, calcium iodate 2%, sodium selenite 1.5%, potassium dihydrogen phosphate 1.5%, surplus are acceptable accessories.
Described auxiliary material is at least a in the auxiliary materials such as zeolite powder, soluble starch, sucrose or lactose.
Take by weighing astragalus polyose, baicalin, peppermint oil wrappage, Honegsukle flower P.E, vitamin C, vitamin E, chromium picolinate, zinc oxide, arginine, tryptophan, glutaminase, sodium sulphate, calcium iodate, sodium selenite, potassium dihydrogen phosphate and auxiliary material according to aforementioned proportion; Mix, promptly make feed addictive of the present invention.
Astragalus polyose described in the above-mentioned feed addictive, baicalin, peppermint oil wrappage, Honegsukle flower P.E can be bought on market.The Chinese medical extract of the astragalus polyose of producing like medicine company limited company of traditional Chinese medicines group, baicalin, peppermint oil wrappage, honeysuckle etc.
Vitamin C described in the above-mentioned feed addictive, vitamin E, chromium picolinate, zinc oxide, arginine, tryptophan, glutaminase, sodium sulphate, calcium iodate, sodium selenite, potassium dihydrogen phosphate and auxiliary material all can be bought on market.As can be from international raw material company of the U.S. or star space medication chemistry Co., Ltd purchase from Changsha.
The method for using of above-mentioned feed addictive, the percentage by weight according to 0.1～0.3% joins above-mentioned feed addictive in the poultry and livestock feed, mixes to get final product.
Feed addictive solubility of the present invention is good, and soaked throwing is given, the feed interpolation can both reach good effect.
The following reaction mechanism that utilization of the present invention possibly exist: the comprehensive compatible combination of Chinese herbal medicine, amino acid, minerals and vitamins; Under anti-stressed condition; Can comprehensively promote the dynamic variation of the metabolism of body internal hormone, immunologic function, nutrition physiology and nutritional need, thereby improve the anti-stress effect of animal body.
Above-mentioned feed addictive can replenish the electrolyte loss that the dehydration of fowl poultry is caused rapidly, and acid-base balance in fast quick-recovery Premeabilisation of cells pressure and the mediation body.Because of chloride ion-containing not, can be for a long time and the high dose throwing give and can not produce side effect such as watery stool.Feed addictive of the present invention in order to alleviate, treatment is various stress;, feed formula soft like loose and watery stool changes, cuts mouth, mycotoxin contamination, vaccine inoculation, heat stress, infectious disease, cold stress, overcrowding, dispensing treatment, transports in the way, poisons for the mode of raising or raw material; Especially heat stress and cold stress are treated the swollen perfect additive of lithate kidney especially.
Compared with prior art, the present invention has following advantage: (1) the present invention can strengthen the anti-stress ability of fowl poultry, is particularly suited for strengthening anti-cold stress and heat stress ability, promotes growth; (2) the present invention can replenish the electrolyte loss that dehydration is caused rapidly, and fast quick-recovery Premeabilisation of cells is pressed and the interior acid-base balance of mediation body; (3) the present invention can be alleviated the anti-poisoning capability of water body of aquatic animal.
The specific embodiment
Below come the present invention is further described based on embodiment, but the present invention is not constituted any restriction.
The preparation of embodiment 1 anti-stress feed addictive of the present invention
Get each component according to following ratio: astragalus polyose 25%, baicalin 25%, peppermint oil wrappage 15%, honeysuckle 15%, vitamin C 3%, vitamin E 3%, chromium picolinate 0.015%, zinc oxide 0.18%, arginine 0.8%, tryptophan 3%, glutaminase 2%, sodium sulphate 2%, calcium iodate 2%, sodium selenite 1.5%, potassium dihydrogen phosphate 1.5%, soluble starch 4.005%; Put into again after above-mentioned material proportionally taken by weighing agitator fully mix get final product feed addictive of the present invention; The product that wherein above-mentioned astragalus polyose, baicalin, peppermint oil wrappage and honeysuckle produce available from medicine company limited company of traditional Chinese medicines group; Said vitamin C, vitamin E, chromium picolinate, zinc oxide, arginine, tryptophan, glutaminase and soluble starch are available from available from Changsha star space medication chemistry Co., Ltd.
The dead mortality comparative test of test example 1 laying cycle of laying hens
(1) feed formula
The control group feed: existing common cooperation laying hen material, its material composition and percentage by weight are: corn 62.00%, big dregs of beans 18.35%; Corn protein powder 3.50%, rapeseed dregs 8.45%, feather meal 0.80%; Stone flour 6.00%, salt 0.35%, mineral substance premix 0.13%; Vitamin premix 0.14%, methionine 0.23%, threonine 0.05%.Putting into agitator after above-mentioned material proportionally taken by weighing again fully mixes and gets final product.
Test group feed: the feed addictive of embodiment 1 joined to mix in the above-mentioned control group feed according to 0.2% ratio get final product.
(2) test is divided into groups and method:
Test is divided into groups: select 1000 laying hens for use, be divided into 2 processing at random, each handles 5 repetitions, and each repeats 100.
Feeding and management and disease prevention and cure: various feedings and managements and disease prevention and cure are by " method that layer breeding handbook (China Agricultyre University Press, 2000.1) provides is carried out, and raises in cages 2 in every cage.Test is carried out in the peace chicken farm in Xiang Tan, Hunan; Be fed to September from June; Measure 6,7,8 respectively, the death rate in four month of September, death rate computing formula is: dead mortality (%)=(laying period dead chicken number+the chicken number is eliminated) laying period/go into to give up hen number * 100.
Table 1 dead mortality comparative test of laying period result
| Time | The dead mortality (%) of control group | The dead mortality (%) of test group |
| June | 0.49 | 0.41 |
| July | 0.47 | 0.36 |
| August | 0.72 | 0.40 |
| September | 0.71 | 0.48 |
| On average | 0.61 | 0.41 |
(3) result's (seeing table 1) test group dead mortality of laying period in June has reduced by 16.33% than control group; Test group dead mortality of laying period in July has reduced by 23.40% than control group; Test group dead mortality of laying period in August has reduced by 44.44% than control group; Test group dead mortality of laying period in September has reduced by 32.39% than control group.Explain that anti-stress feed addictive of the present invention has significantly improved the anti-heat stress ability of laying hen at high temperature season, and strengthened immune effect.
The average butterfat percnetage contrast test of test example 2 milk cows
(1) feed formula
Control group feed: get according to following component and percentage by weight: corn 15.00%, inferior powder 25.00%, corn germ cake 18.00%, DDGS 15.00%; The cottonseed dregs of rice 12.00%, oily chaff 8.00%, molasses fermented liquid 4.00%; Stone flour 2.00%, salt 0.40%, calcium monohydrogen phosphate 0.60%.Putting into agitator after above-mentioned material proportionally taken by weighing again fully mixes and gets final product.
Test group feed: join in the control group feed according to the feed addictive of 0.3% ratio, mix, be the test group feed with embodiment 1.
(2) test is divided into groups and test method: select 20 lactating cows for use, be divided into 2 groups at random, 10 every group test milk cows.
Feeding and management and disease prevention and cure: various feedings and managements and disease prevention and cure are undertaken by the specification requirement that " modern raising dairy cattle practical technique " (scientific and technical literature publishing house, 2006.9) provide.Raise to January from December in pilot scale base, Changping, Institute of Feeds,China Academy of Agriculture Sciences Beijing, every ox feed mixed fodder and hay, drylot feeding raised for 4 weeks.Each free activity morning and afternoon every day once, each 1 hour; Grooming every day 1～2 time is carried out at sports ground before milking.8 of mornings and point in afternoons six, respectively milk once, measure average butterfat percnetage.Average butterfat percnetage (%)=∑ (F * M)/∑ M, ∑ is the summation of accumulative total, and F is each fat content of measuring, and M is the milk production of this sub-sampling phase.
The average butterfat percnetage comparative test result of table 2 milk cow
| Time | Before the processing | Handled for 1 week | Handled for 2 weeks | Handled for 3 weeks | Handled for 4 weeks |
| Control group butterfat percnetage (%) | 3.36 | 3.36 | 3.35 | 3.35 | 3.35 |
| Test group butterfat percnetage (%) | 3.35 | 3.42 | 3.51 | 3.63 | 3.67 |
(3) result's (seeing table 2) test group improves 1.75～8.72% than the average butterfat percnetage of control group milk cow, explains that feed addictive of the present invention significantly promotes fat of milk cow content to increase, and has improved the tolerance of body to cold stress.
Test example 3 pig serum inorganic ions concentration contrast tests
(1) feed formula
The control group feed: existing common cooperation growing swine material, its material composition and percentage by weight are: corn 71.00%, big dregs of beans 14.60%; Wheat bran 10.00%, stone flour 0.80%, calcium monohydrogen phosphate 2.40%; Mineral substance premix 0.55%, vitamin premix 0.65%.Putting into agitator after above-mentioned material proportionally taken by weighing again fully mixes and gets final product.
Test group feed: the feed addictive of embodiment 1 joined to mix in the control group feed according to 0.2% ratio get final product.
(2) test material and method
Test is divided into groups: select 80 close, healthy binary of body weight " Du * length " weanling pig of mix for use, be divided into 2 processing at random, each handles 5 repetitions, 8 of each repetitions.
Feeding and management and disease prevention and cure: various feedings and managements and disease prevention and cure are carried out stable breeding, 8 on every hurdle by the method that " Beijing six horse standards raise pigs pattern " (Chinese agriculture publishing house, 2006.8) provide.Be fed to September from July, 42 days experimental periods, were in the 42nd day 7:00～8:00; Each repeats to randomly draw 4 pigs; Vena cava anterior is taken a blood sample on an empty stomach, Measuring Pig serum inorganic ions concentration, and the kit that method of testing is built up bio-engineering research and provided referring to Nanjing is measured.
Table 3 pig serum inorganic ions concentration comparative test result
| Title | K + (nmol/L) | Na + (nmol/L) | Cl - (nmol/L) | Mg + (nmol/L) | Ca + (nmol/L) |
| Control group | 7.22 | 150.18 | 110.55 | 2.27 | 8.26 |
| Test group | 8.31 | 146.69 | 109.18 | 2.23 | 8.96 |
(3) result's (seeing table 3), test group K
+Content is higher than control group, has improved 13.12%, explains that feed addictive of the present invention has to slow down hypokalemic effect; Test group Na
+Content is lower than control group, reduces by 2.23%, explains that feed addictive of the present invention has the effect that slows down hypernatremia, has explained that the pig antagonism stress adapt to relevant; Test group Ca
+Content is higher than control group, has improved 7.81%, explains that feed addictive of the present invention has to slow down the effect of falling calcium.Explain that feed addictive of the present invention can relax heat stress and bring hypernatremia and hyperchloremia phenomenon, can alleviate low blood potassium that heat stress causes and fall calcium trend.
The contrast test of the anti-ammonia stress ability of test example 4 Tilapia mossambicas
(1) feed formula
The control group feed: existing common cooperation Tilapia mossambica material, its material composition and percentage by weight are: corn 22.00%, big dregs of beans 28.00%; The cottonseed dregs of rice 30.00%, fish meal 8.00%, fish oil 2.00%; DDGS6.00%, mineral substance premix 2.00%, vitamin premix 2.00%.Putting into agitator after above-mentioned material proportionally taken by weighing again fully mixes and gets final product.
The test group feed: the feed addictive that embodiment 1 is made joins to mix in the above-mentioned cooperation Tilapia mossambica material according to 0.2% ratio and gets final product.
(2) test material and method:
Test is divided into groups: select for use with a collection of prime fish kind 1000 tails, raise and train in the indoor circulation water cultivating system of test fish sterilization back.During raising and train, throw something and feed in right amount for 4 times every day, the time is 8:00,10:00,13:00 and 16:00.Raising and train feed is the control group feed, and the time of raising and train is 14d.After on-test, with initial weight be the healthy Tilapia mossambica mean allocation of 18.76 ± 0.099g 2 processed group, each handles 6 repetitions, puts fish 30 tails respectively in 12 breed tanks.Experiment is 63d altogether.
Feeding and management and disease prevention and cure: various feedings and managements and disease prevention and cure are undertaken by the method that " nuisanceless Tilapia mossambica standardized production " (Chinese agriculture publishing house, 2006.1) provide.
Stopped eating in the 62nd day and the 63rd day.Anti-ammonia stress ability contrast test is under the natural conditions, adopts the hydrostatic formula, and the intoxicating mode is directly to contact intoxicating.The 63rd day, earlier each aquarium is mixed with the required ammonia concentration of test, with 2 processed group, the test fish of 6 breed tanks is put into and contains the ammonia test groove in 20 minutes.
Experiment concurrence 12h, since 2h, the death rate of every 2h statistics single test fish.Gently sting the caudal peduncle position with glass rod, fish decidable reactionless and that the gill cover stops to open and close is death in 3～5 minutes, and the fish of in time checkmating is pulled out.In this on-test 2h, the test fish does not show special abnormal behaviour.Behind the 2h, individual one is bolted to swim and is scurried, and is many with the side trip; On one's deathbed be spasticity before, the gill cover opens and closes slightly; Lose motion and sensing ability, lie at the bottom and death with the side.Dead the fish body gill cover and body surface have little congested phenomenon; The body colour blackout, body surface has more mucous secretion.6 test fishes of culturing tank are all dead in 12h.
The comparative test result of the anti-ammonia stress ability of table 4 Tilapia mossambica
| Time | Control group cumulative mortality (%) | Test group cumulative mortality (%) |
| 4h | 50 | 18 |
| 6h | 63 | 50 |
| 8h | 100 | 58 |
| 10h | - | 85 |
Result's (seeing table 4), during 4h, the cumulative mortality of control group test fish has reached 50%, and the cumulative mortality of test group fish is 18%; During 6h, the cumulative mortality of control group fish has reached 63%, and the cumulative mortality of test group fish is 50%; During 8h, the cumulative mortality of control group fish has reached 100%, and the cumulative mortality of test group fish is 58%; During 10h, the cumulative mortality of test group fish reaches 85%, and promptly with under the equal time, the cumulative mortality of test group fish all significantly is lower than the cumulative mortality of control group fish.Explain that feed addictive of the present invention has improved the anti-ammonia stress ability of Tilapia mossambica.
Claims (3)
1. anti-stress feed addictive; It is characterized in that its constituent and percentage by weight are: astragalus polyose 15～30%, baicalin 15～30%, peppermint oil wrappage 10～20%, honeysuckle abstract 10～20%, vitamin C 0.5～5%, vitamin E 0.5～5%, chromium picolinate 0.001～0.02%, zinc oxide 0.05～0.3%, arginine 0.1～1%, tryptophan 1～5%, glutaminase 1～5%, sodium sulphate 1～5%, calcium iodate 1～3%, sodium selenite 1～3%, potassium dihydrogen phosphate 1～3%, surplus are auxiliary material.
2. according to the described anti-stress feed addictive of claim 1; It is characterized in that its constituent and percentage by weight thereof are: astragalus polyose 25%, baicalin 25%, peppermint oil wrappage 15%, honeysuckle abstract 15%, vitamin C 3%, vitamin E 3%, chromium picolinate 0.015%, zinc oxide 0.18%, arginine 0.8%, tryptophan 3%, glutaminase 2%, sodium sulphate 2%, calcium iodate 2%, sodium selenite 1.5%, potassium dihydrogen phosphate 1.5%, surplus are auxiliary material.
3. according to claim 1 or 2 described anti-stress feed addictives, it is characterized in that described auxiliary material is at least a in zeolite powder, soluble starch, sucrose or the lactose.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200810116768XA CN101313731B (en) | 2008-07-17 | 2008-07-17 | Anti-stress feedstuff additive |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200810116768XA CN101313731B (en) | 2008-07-17 | 2008-07-17 | Anti-stress feedstuff additive |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101313731A CN101313731A (en) | 2008-12-03 |
| CN101313731B true CN101313731B (en) | 2012-02-22 |
Family
ID=40104987
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN200810116768XA Expired - Fee Related CN101313731B (en) | 2008-07-17 | 2008-07-17 | Anti-stress feedstuff additive |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101313731B (en) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102144721A (en) * | 2011-04-20 | 2011-08-10 | 赵景辉 | Application of astragalus to poultry feed additive |
| CN102210404B (en) * | 2011-05-18 | 2012-05-23 | 双胞胎饲料有限公司 | Feed additive capable of effectively enhancing immunologic function and improving pork quality |
| CN102894210B (en) * | 2012-08-27 | 2013-12-18 | 广东海大集团股份有限公司 | Anti-stress Chinese herbal medicine composite feedstuff additive specially used for penaeus vannamei |
| CN103621806B (en) * | 2013-10-26 | 2016-01-13 | 铜陵市银树生态养殖有限责任公司 | A kind of formula forage alleviating heat stress of layer |
| CN103734467B (en) * | 2013-12-23 | 2015-09-23 | 安徽农业大学 | A kind of bird inlay diet dead season composition |
| CN103734537B (en) * | 2014-01-09 | 2015-08-26 | 中国水产科学研究院淡水渔业研究中心 | A kind of method of anti-Streptococcus iniae infection ability when improving gift tilapia Heat-temperature stress |
| CN104206903B (en) * | 2014-09-02 | 2018-08-10 | 北京爱绿生物科技有限公司 | A kind of Chinese herbal medicine Antistress agent composition and its application |
| CN104222523A (en) * | 2014-09-26 | 2014-12-24 | 中国农业科学院北京畜牧兽医研究所 | Anti-stress feed additive and preparation method thereof |
| CN104222690A (en) * | 2014-10-10 | 2014-12-24 | 广州傲农生物科技有限公司 | Premix for reducing stress response of weaned piglets and preparation method and application of premix |
| CN105614002B (en) * | 2014-11-07 | 2020-11-03 | 北京大北农科技集团股份有限公司 | Antioxidant stress dairy cow feed additive, premix, concentrate and batch |
| CN105878397A (en) * | 2014-11-24 | 2016-08-24 | 李雷 | Composition capable of regulating transportation stress of cattle and sheep |
| CN104686807A (en) * | 2015-03-26 | 2015-06-10 | 无锡正大畜禽有限公司 | Anti-stress vitamin premix compound for beasts and birds and preparation method thereof |
| CN104705495A (en) * | 2015-03-31 | 2015-06-17 | 江西中成人药业有限公司 | Special traditional Chinese medicine polysaccharide feed additive for pets |
| CN104799120B (en) * | 2015-05-18 | 2018-03-13 | 广东科润生物制药有限公司 | A kind of feed addictive for being used to improve chick low-temperature resistance stress |
| CN105285323A (en) * | 2015-08-05 | 2016-02-03 | 大连岭前农业专业合作社 | Selenium-rich SOD cherry plant composite drug effect feed for quails |
| CN105053642A (en) * | 2015-08-05 | 2015-11-18 | 大连岭前农业专业合作社 | Quail selenium-enriched SOD apple plant compound drug efficacy feed |
| CN105029086A (en) * | 2015-08-26 | 2015-11-11 | 中国科学院亚热带农业生态研究所 | Application of alpha-oxoglutarate disodium in preparation of pig feed |
| CN105029087A (en) * | 2015-08-26 | 2015-11-11 | 中国科学院亚热带农业生态研究所 | Application of alpha-ketoglutaric acid dipotassium to preparation of pig feed |
| CN105166418A (en) * | 2015-10-13 | 2015-12-23 | 临沂大学 | Anti-heat stress feed additives for rabbits and preparation method thereof |
| CN106615680A (en) * | 2015-11-03 | 2017-05-10 | 瑞普（天津）生物药业有限公司 | Anti-stress feed additive |
| CN105519816B (en) * | 2016-01-29 | 2019-08-16 | 济南和美华饲料有限公司 | A kind of additive improving laying hen anti-stress ability |
| CN106421307A (en) * | 2016-10-31 | 2017-02-22 | 南宁学院 | Heat stress resistant agent used for chicken and preparation method thereof |
| CN106923080A (en) * | 2017-03-08 | 2017-07-07 | 广东海洋大学 | A kind of feed addictive of the raising Duo anti-transport stress power of Lin Xi juvenile fish |
| CN107927414A (en) * | 2017-11-03 | 2018-04-20 | 佛山科学技术学院 | Compound resisting stress additive, egg duck feed suitable for laying duck cultivation |
| CN108576403A (en) * | 2018-04-03 | 2018-09-28 | 广东省农业科学院动物科学研究所 | Application of the selenium in improving yellow catfish growing performance, oxidation resistance, low-temperature resistance stress ability |
| CN109601708A (en) * | 2018-12-27 | 2019-04-12 | 河南牧业经济学院 | A kind of anti-heat stress feed additive and preparation method thereof |
| CN110326720B (en) * | 2019-08-22 | 2023-09-01 | 济南中牧澳利生物科技有限责任公司 | Duck feed additive |
| CN111903836A (en) * | 2020-05-26 | 2020-11-10 | 广东海洋大学 | Feed additive for improving high-temperature stress resistance of marine cultured animals and preparation method and application thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1363366A (en) * | 2002-01-14 | 2002-08-14 | 马文汉 | Antivirus defervescent |
| CN1634345A (en) * | 2004-10-26 | 2005-07-06 | 张士更 | External used Chinese traditional medicine preparation for treating premature ejaculation and production method thereof |
-
2008
- 2008-07-17 CN CN200810116768XA patent/CN101313731B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1363366A (en) * | 2002-01-14 | 2002-08-14 | 马文汉 | Antivirus defervescent |
| CN1634345A (en) * | 2004-10-26 | 2005-07-06 | 张士更 | External used Chinese traditional medicine preparation for treating premature ejaculation and production method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 许霖等.明胶在薄荷微胶囊中的应用.《明胶科学与技术》.1987,(第03期), * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN101313731A (en) | 2008-12-03 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101313731B (en) | Anti-stress feedstuff additive | |
| CN103141706B (en) | Chinese herbal medicine lactagogue feed for sow and preparation method of feed | |
| CN102119983B (en) | Traditional Chinese medicine composition for preventing and treating heat stress of livestock and poultry | |
| CN106614329A (en) | Ecological breeding method of small-ear pigs | |
| CN104664175B (en) | A kind of ramie supports goose method and its special feed | |
| CN108450672A (en) | A kind of sows in perinatal period mixed feed and preparation method thereof | |
| CN1265838A (en) | Process for high-efficienctly preparing grain-saving no-toxicity no-chemicals ingredient of animal fodder and the prepared products | |
| Chernogradskaya et al. | Influence of zeolite honguruu on growth and development, digestibility and metabolism of geese | |
| CN101642191B (en) | Natural plant feed additives for livestock and poultry feeding industry | |
| CN101331914B (en) | Livestock and poultry feed additive | |
| CN105231066A (en) | Formula and preparation method of duckling forage formula | |
| CN106036075A (en) | Green and environment-friendly milk cow feed additive | |
| CN106721367A (en) | Improve mixed feed of female rabbit reproductive performance and preparation method thereof and method for breeding | |
| RU2357424C2 (en) | Pig fodder additive and method of pig feeding | |
| CN106804904A (en) | A kind of cow feed additive of Chinese herbal medicine | |
| CN106578484A (en) | Chinese herbal medicine feed supplement for sows in suckling period | |
| CN108617856A (en) | Application of the zinc benzoate in preparing animal feed additive | |
| CN106342752A (en) | Raising management technique and method for fattening and gaining weight of cattle | |
| Lobna et al. | The effect of feeding rosemary and marjoram on reproductive performance of rabbit does under Sinai conditions | |
| CN104322905A (en) | Pig feed containing fennel dregs and preparation method thereof | |
| Klyuchnikova et al. | Use of endemic plants in dairy cattle breeding in the Middle Amur region | |
| CN103988986A (en) | Traditional Chinese medicine poultry feed | |
| CN104886356A (en) | Animal stress-resistant Chinese herbal medicine additive and preparation method thereof | |
| CN1757306B (en) | Forage additive made from traditional Chinese herb medicines, and its prepn. method | |
| CN110521672B (en) | Bamboo rat breeding method |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| ASS | Succession or assignment of patent right |
Owner name: BEIJING HUAQING KECHUANG TECHNOLOGY DEVELOPMENT CO Free format text: FORMER OWNER: BEIJING ZHONGNONG BOLE TECHNOLOGY DEVELOPMENT CO., LTD. Effective date: 20130418 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| C53 | Correction of patent for invention or patent application | ||
| CB03 | Change of inventor or designer information |
Inventor after: Li Qin Inventor before: Yan Hongfa Inventor before: Luo Fahong Inventor before: He He Inventor before: Li Rongxian Inventor before: Li Hengxin |
|
| COR | Change of bibliographic data |
Free format text: CORRECT: ADDRESS; FROM: 100081 HAIDIAN, BEIJING TO: 100192 HAIDIAN, BEIJING Free format text: CORRECT: INVENTOR; FROM: YAN HONGFA LUO FAHONG HE HE LI RONGXIAN LI HENGXIN TO: LI QIN |
|
| TR01 | Transfer of patent right |
Effective date of registration: 20130418 Address after: 100192, room 307, block A, Yongtai Innovation Park, Yongtai, 25 Middle Road, Haidian District, Beijing, Zhongguancun Patentee after: Beijing Huaqing Science & Technology Development Co. Ltd. Address before: 100081, room 212, feed Research Institute, Chinese Academy of Agricultural Sciences, 12 South Avenue, Beijing, Zhongguancun Patentee before: Beijing Zhongnong Bole Technology Development Co., Ltd. |
|
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20120222 Termination date: 20180717 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |