CN101282963A - 用作治疗药的吡唑衍生物 - Google Patents
用作治疗药的吡唑衍生物 Download PDFInfo
- Publication number
- CN101282963A CN101282963A CNA2006800374501A CN200680037450A CN101282963A CN 101282963 A CN101282963 A CN 101282963A CN A2006800374501 A CNA2006800374501 A CN A2006800374501A CN 200680037450 A CN200680037450 A CN 200680037450A CN 101282963 A CN101282963 A CN 101282963A
- Authority
- CN
- China
- Prior art keywords
- base
- methyl
- pyrazole
- piperidines
- dichloro benzene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Endocrinology (AREA)
- Pain & Pain Management (AREA)
- Diabetes (AREA)
- Psychology (AREA)
- Immunology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Hospice & Palliative Care (AREA)
- Addiction (AREA)
- Child & Adolescent Psychology (AREA)
- Reproductive Health (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0516661.6A GB0516661D0 (en) | 2005-08-13 | 2005-08-13 | Therapeutic agents |
| GB0516661.6 | 2005-08-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101282963A true CN101282963A (zh) | 2008-10-08 |
Family
ID=35098275
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2006800374501A Pending CN101282963A (zh) | 2005-08-13 | 2006-08-09 | 用作治疗药的吡唑衍生物 |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP1915364A1 (de) |
| JP (1) | JP2009504717A (de) |
| KR (1) | KR20080039939A (de) |
| CN (1) | CN101282963A (de) |
| AR (1) | AR055368A1 (de) |
| AU (1) | AU2006281300A1 (de) |
| BR (1) | BRPI0614626A2 (de) |
| CA (1) | CA2619228A1 (de) |
| EC (1) | ECSP088250A (de) |
| GB (1) | GB0516661D0 (de) |
| IL (1) | IL188759A0 (de) |
| MX (1) | MX2008002065A (de) |
| NO (1) | NO20080372L (de) |
| RU (1) | RU2008108179A (de) |
| TW (1) | TW200728300A (de) |
| UY (1) | UY29741A1 (de) |
| WO (1) | WO2007020388A1 (de) |
| ZA (1) | ZA200800698B (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102008015032A1 (de) | 2008-03-17 | 2009-09-24 | Aicuris Gmbh & Co. Kg | Substituierte Pyrazolamide und ihre Verwendung |
| DE102008015033A1 (de) | 2008-03-17 | 2009-09-24 | Aicuris Gmbh & Co. Kg | Substituierte (Pyrazolyl-carbonyl)imidazolidinone und ihre Verwendung |
| DE102008062863A1 (de) | 2008-12-17 | 2010-06-24 | Aicuris Gmbh & Co. Kg | Substituierte (Thiophenyl-carbonyl)imidazolidinone und ihre Verwendung |
| DE102008062878A1 (de) | 2008-12-17 | 2010-06-24 | Aicuris Gmbh & Co. Kg | Substituierte Furancarboxamide und ihre Verwendung |
| DE102009036604A1 (de) | 2009-07-30 | 2011-02-03 | Aicuris Gmbh & Co. Kg | Substituierte Bis-Arylpyrazolamide mit terminaler primärer Amidfunktionalisierung und ihre Verwendung |
| DE102011055815A1 (de) | 2011-11-29 | 2013-05-29 | Aicuris Gmbh & Co. Kg | Carboxamid-substituierte Heteroaryl-Pyrazole und ihre Verwendung |
| DE102012016908A1 (de) | 2012-08-17 | 2014-02-20 | Aicuris Gmbh & Co. Kg | Tris-(Hetero)Aryl-Pyrazole und ihre Verwendung |
| CN105061227A (zh) * | 2015-07-27 | 2015-11-18 | 广东先强药业有限公司 | 一种环保的盐酸利托君生产方法 |
| WO2020123855A1 (en) | 2018-12-12 | 2020-06-18 | University Of Washington | Inhibitor compounds for male contraception |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4419078B2 (ja) * | 2002-12-02 | 2010-02-24 | アステラス製薬株式会社 | ピラゾール誘導体 |
| US7247628B2 (en) * | 2002-12-12 | 2007-07-24 | Pfizer, Inc. | Cannabinoid receptor ligands and uses thereof |
| ES2329915T3 (es) * | 2004-02-20 | 2009-12-02 | Astrazeneca Ab | Derivados de 1,5-difenilpirazol 3-sustituidos utiles como moduladores de cb1. |
-
2005
- 2005-08-13 GB GBGB0516661.6A patent/GB0516661D0/en not_active Ceased
-
2006
- 2006-08-01 TW TW095128062A patent/TW200728300A/zh unknown
- 2006-08-08 AR ARP060103449A patent/AR055368A1/es unknown
- 2006-08-09 CA CA002619228A patent/CA2619228A1/en not_active Abandoned
- 2006-08-09 KR KR1020087004570A patent/KR20080039939A/ko not_active Application Discontinuation
- 2006-08-09 RU RU2008108179/04A patent/RU2008108179A/ru not_active Application Discontinuation
- 2006-08-09 MX MX2008002065A patent/MX2008002065A/es not_active Application Discontinuation
- 2006-08-09 CN CNA2006800374501A patent/CN101282963A/zh active Pending
- 2006-08-09 EP EP06779114A patent/EP1915364A1/de not_active Withdrawn
- 2006-08-09 BR BRPI0614626-0A patent/BRPI0614626A2/pt not_active Application Discontinuation
- 2006-08-09 AU AU2006281300A patent/AU2006281300A1/en not_active Abandoned
- 2006-08-09 JP JP2008526536A patent/JP2009504717A/ja active Pending
- 2006-08-09 WO PCT/GB2006/002990 patent/WO2007020388A1/en active Application Filing
- 2006-08-11 UY UY29741A patent/UY29741A1/es not_active Application Discontinuation
-
2008
- 2008-01-14 IL IL188759A patent/IL188759A0/en unknown
- 2008-01-21 NO NO20080372A patent/NO20080372L/no not_active Application Discontinuation
- 2008-01-23 ZA ZA200800698A patent/ZA200800698B/xx unknown
- 2008-03-07 EC EC2008008250A patent/ECSP088250A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GB0516661D0 (en) | 2005-09-21 |
| KR20080039939A (ko) | 2008-05-07 |
| ZA200800698B (en) | 2009-01-28 |
| AR055368A1 (es) | 2007-08-22 |
| CA2619228A1 (en) | 2007-02-22 |
| RU2008108179A (ru) | 2009-09-20 |
| MX2008002065A (es) | 2008-04-16 |
| AU2006281300A1 (en) | 2007-02-22 |
| TW200728300A (en) | 2007-08-01 |
| BRPI0614626A2 (pt) | 2012-12-04 |
| ECSP088250A (es) | 2008-04-28 |
| IL188759A0 (en) | 2008-08-07 |
| WO2007020388A1 (en) | 2007-02-22 |
| JP2009504717A (ja) | 2009-02-05 |
| UY29741A1 (es) | 2007-03-30 |
| NO20080372L (no) | 2008-04-16 |
| EP1915364A1 (de) | 2008-04-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Open date: 20081008 |