CN101265226B - 化合物和释放前列环素类似物的方法 - Google Patents

化合物和释放前列环素类似物的方法 Download PDF

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CN101265226B
CN101265226B CN2008100861999A CN200810086199A CN101265226B CN 101265226 B CN101265226 B CN 101265226B CN 2008100861999 A CN2008100861999 A CN 2008100861999A CN 200810086199 A CN200810086199 A CN 200810086199A CN 101265226 B CN101265226 B CN 101265226B
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treprostinil
ester
purposes
replacement
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CN101265226A (zh
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K·法雷斯
D·莫托拉
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United Therapeutics Corp
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United Therapeutics Corp
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    • C07C229/06Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
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CN2008100861999A 2003-05-22 2004-05-24 化合物和释放前列环素类似物的方法 Expired - Lifetime CN101265226B (zh)

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CA2959852A1 (en) * 2003-05-22 2005-01-27 United Therapeutics Corporation Compounds and methods for delivery of prostacyclin analogs
DE602004022982D1 (de) * 2003-12-16 2009-10-15 United Therapeutics Corp Verwendung von treprostinil zur verbesserung der nierenfunktion
US20090124697A1 (en) 2003-12-16 2009-05-14 United Therapeutics Corporation Inhalation formulations of treprostinil
US8765813B2 (en) 2003-12-16 2014-07-01 United Therapeutics Corporation Use of treprostinil to treat and prevent ischemic lesions
WO2005099680A2 (en) 2004-04-12 2005-10-27 United Therapeutics, Inc. Use of treprostinil to treat neuropathic diabetic foot ulcers
BRPI0613315A2 (pt) * 2005-06-02 2009-06-16 Univ Colorado usos de análogos de prostaciclina
US8747897B2 (en) * 2006-04-27 2014-06-10 Supernus Pharmaceuticals, Inc. Osmotic drug delivery system
KR101390579B1 (ko) 2006-05-15 2014-05-19 유나이티드 세러퓨틱스 코오포레이션 정량 흡입기를 사용한 트레프로스티닐 투여
DE102006026786A1 (de) 2006-06-07 2007-12-13 Joachim Kern Dosierinhalator
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