CN101265226B - 化合物和释放前列环素类似物的方法 - Google Patents
化合物和释放前列环素类似物的方法 Download PDFInfo
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- CN101265226B CN101265226B CN2008100861999A CN200810086199A CN101265226B CN 101265226 B CN101265226 B CN 101265226B CN 2008100861999 A CN2008100861999 A CN 2008100861999A CN 200810086199 A CN200810086199 A CN 200810086199A CN 101265226 B CN101265226 B CN 101265226B
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- treprostinil
- ester
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- replacement
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- 0 CCCCC[C@@](CC[C@@](CC1)[C@@]2[C@@]1Cc1c(*)cccc1C2)O Chemical compound CCCCC[C@@](CC[C@@](CC1)[C@@]2[C@@]1Cc1c(*)cccc1C2)O 0.000 description 1
- AMLGYPBESXMWIK-SPFHDNFTSA-N CCCCC[C@H](CC[C@@H]([C@@H](C1)O)C(Cc2ccc3)C1Cc2c3OCC(OC)=O)O Chemical compound CCCCC[C@H](CC[C@@H]([C@@H](C1)O)C(Cc2ccc3)C1Cc2c3OCC(OC)=O)O AMLGYPBESXMWIK-SPFHDNFTSA-N 0.000 description 1
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- Diabetes (AREA)
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- Pain & Pain Management (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US47240703P | 2003-05-22 | 2003-05-22 | |
| US60/472407 | 2003-05-22 |
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| CNB2004800205699A Division CN100558351C (zh) | 2003-05-22 | 2004-05-24 | 化合物和释放前列环素类似物的方法 |
Publications (2)
| Publication Number | Publication Date |
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| CN101265226A CN101265226A (zh) | 2008-09-17 |
| CN101265226B true CN101265226B (zh) | 2013-04-24 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN2012101586478A Pending CN102697790A (zh) | 2003-05-22 | 2004-05-24 | 化合物和释放前列环素类似物的方法 |
| CN2009101787386A Expired - Lifetime CN101780092B (zh) | 2003-05-22 | 2004-05-24 | 化合物和释放前列环素类似物的方法 |
| CNB2004800205699A Expired - Lifetime CN100558351C (zh) | 2003-05-22 | 2004-05-24 | 化合物和释放前列环素类似物的方法 |
| CN2008100861999A Expired - Lifetime CN101265226B (zh) | 2003-05-22 | 2004-05-24 | 化合物和释放前列环素类似物的方法 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN2012101586478A Pending CN102697790A (zh) | 2003-05-22 | 2004-05-24 | 化合物和释放前列环素类似物的方法 |
| CN2009101787386A Expired - Lifetime CN101780092B (zh) | 2003-05-22 | 2004-05-24 | 化合物和释放前列环素类似物的方法 |
| CNB2004800205699A Expired - Lifetime CN100558351C (zh) | 2003-05-22 | 2004-05-24 | 化合物和释放前列环素类似物的方法 |
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| CA (4) | CA2959852A1 (enExample) |
| ES (2) | ES2622471T5 (enExample) |
| WO (1) | WO2005007081A2 (enExample) |
Families Citing this family (86)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10214983A1 (de) * | 2002-04-04 | 2004-04-08 | TransMIT Gesellschaft für Technologietransfer mbH | Vernebelbare Liposomen und ihre Verwendung zur pulmonalen Applikation von Wirkstoffen |
| CA2959852A1 (en) * | 2003-05-22 | 2005-01-27 | United Therapeutics Corporation | Compounds and methods for delivery of prostacyclin analogs |
| DE602004022982D1 (de) * | 2003-12-16 | 2009-10-15 | United Therapeutics Corp | Verwendung von treprostinil zur verbesserung der nierenfunktion |
| US20090124697A1 (en) | 2003-12-16 | 2009-05-14 | United Therapeutics Corporation | Inhalation formulations of treprostinil |
| US8765813B2 (en) | 2003-12-16 | 2014-07-01 | United Therapeutics Corporation | Use of treprostinil to treat and prevent ischemic lesions |
| WO2005099680A2 (en) | 2004-04-12 | 2005-10-27 | United Therapeutics, Inc. | Use of treprostinil to treat neuropathic diabetic foot ulcers |
| BRPI0613315A2 (pt) * | 2005-06-02 | 2009-06-16 | Univ Colorado | usos de análogos de prostaciclina |
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2012
- 2012-03-21 JP JP2012063484A patent/JP2012162539A/ja not_active Withdrawn
- 2012-07-26 US US13/558,757 patent/US8536363B2/en not_active Expired - Fee Related
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2013
- 2013-05-31 US US13/906,585 patent/US9050311B2/en not_active Expired - Lifetime
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2014
- 2014-09-18 US US14/490,014 patent/US9199908B2/en not_active Expired - Lifetime
-
2015
- 2015-05-13 US US14/710,694 patent/US9278901B2/en not_active Expired - Lifetime
- 2015-10-13 US US14/881,379 patent/US9422223B2/en not_active Expired - Lifetime
- 2015-10-28 US US14/925,084 patent/US9624156B2/en not_active Expired - Fee Related
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2016
- 2016-08-17 US US15/239,014 patent/US9878972B2/en not_active Expired - Lifetime
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2018
- 2018-01-19 US US15/875,101 patent/US20180141891A1/en not_active Abandoned
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2019
- 2019-07-23 US US16/519,491 patent/US10947177B2/en not_active Expired - Fee Related
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2020
- 2020-02-07 US US16/784,720 patent/US20200181057A1/en not_active Abandoned
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2021
- 2021-10-06 US US17/495,141 patent/US11292758B2/en not_active Expired - Lifetime
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2022
- 2022-04-04 US US17/712,566 patent/US20220289660A1/en not_active Abandoned
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4306075A (en) * | 1980-03-28 | 1981-12-15 | The Upjohn Company | Composition and process |
| US5234953A (en) * | 1990-05-24 | 1993-08-10 | Burroughs Wellcome Co. | Treatment of congestive heart failure |
| US6242482B1 (en) * | 2000-06-05 | 2001-06-05 | United Therapeutics Corporation | Prostaglandin compounds and derivatives thereof, compositions containing the same and method of using the same for the treatment of congestive heart failure |
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