CN101224195A - 一种硫酸头孢匹罗原料的合成方法及其用途 - Google Patents
一种硫酸头孢匹罗原料的合成方法及其用途 Download PDFInfo
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- CN101224195A CN101224195A CNA2008100011903A CN200810001190A CN101224195A CN 101224195 A CN101224195 A CN 101224195A CN A2008100011903 A CNA2008100011903 A CN A2008100011903A CN 200810001190 A CN200810001190 A CN 200810001190A CN 101224195 A CN101224195 A CN 101224195A
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组分 | 实施例2 | 实施例3 | 实施例4 | 实施例5 | 实施例6 | 实施例6 |
硫酸头孢匹罗(无菌粉)/g | 1000 | 1000 | 500 | 500 | 2000 | 2000 |
无水碳酸钠(无菌粉)/g | 250 | 125 | 100 | 160 | 400 | 200 |
每瓶有效成分重量/g | 1 | 1 | 0.5 | 0.5 | 2 | 2 |
硫酸头孢匹罗样品 | 1月后PH | 2月后PH | 3月后PH | 6月后PH |
本发明 | 6.0 | 6.0 | 5.8 | 5.7 |
专利CN2004100658900 | 3.94 | 3.94 | 3.90 | 3.89 |
样品 | 1月后主药量(%) | 2月后主药量(%) | 3月后主药量(%) | 6月后主药量(%) |
实施例1 | 99.9 | 99.9 | 99.8 | 99.7 |
实施例2 | 99.9 | 99.8 | 99.8 | 99.6 |
实施例3 | 99.9 | 99.8 | 99.7 | 99.6 |
Claims (7)
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CNB2008100011903A CN100484526C (zh) | 2008-01-18 | 2008-01-18 | 一种硫酸头孢匹罗原料的合成方法及其用途 |
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CN101224195A true CN101224195A (zh) | 2008-07-23 |
CN100484526C CN100484526C (zh) | 2009-05-06 |
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Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102584856A (zh) * | 2011-12-27 | 2012-07-18 | 开封豫港制药有限公司 | 硫酸头孢匹罗的制备方法 |
CN103127128A (zh) * | 2013-03-08 | 2013-06-05 | 海南卫康制药(潜山)有限公司 | 注射用硫酸头孢匹罗药物组合物粉针剂 |
CN103224505A (zh) * | 2013-05-27 | 2013-07-31 | 华北制药河北华民药业有限责任公司 | 一种硫酸头孢匹罗的制备方法 |
CN103601738A (zh) * | 2013-12-04 | 2014-02-26 | 哈药集团制药总厂 | 一种头孢匹罗氢碘酸盐的制备方法 |
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2008
- 2008-01-18 CN CNB2008100011903A patent/CN100484526C/zh active Active
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102584856A (zh) * | 2011-12-27 | 2012-07-18 | 开封豫港制药有限公司 | 硫酸头孢匹罗的制备方法 |
CN103127128A (zh) * | 2013-03-08 | 2013-06-05 | 海南卫康制药(潜山)有限公司 | 注射用硫酸头孢匹罗药物组合物粉针剂 |
CN103224505A (zh) * | 2013-05-27 | 2013-07-31 | 华北制药河北华民药业有限责任公司 | 一种硫酸头孢匹罗的制备方法 |
CN103224505B (zh) * | 2013-05-27 | 2015-10-14 | 华北制药河北华民药业有限责任公司 | 一种硫酸头孢匹罗的制备方法 |
CN103601738A (zh) * | 2013-12-04 | 2014-02-26 | 哈药集团制药总厂 | 一种头孢匹罗氢碘酸盐的制备方法 |
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