CN101112523A - Chinese traditional medicine composition for treating embryonic diapause - Google Patents

Chinese traditional medicine composition for treating embryonic diapause Download PDF

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Publication number
CN101112523A
CN101112523A CNA2007101210327A CN200710121032A CN101112523A CN 101112523 A CN101112523 A CN 101112523A CN A2007101210327 A CNA2007101210327 A CN A2007101210327A CN 200710121032 A CN200710121032 A CN 200710121032A CN 101112523 A CN101112523 A CN 101112523A
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China
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parts
chinese medicine
radix
traditional chinese
medicine composition
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CNA2007101210327A
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Chinese (zh)
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王信锁
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Beijing Yixintang Medicine Institute
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Beijing Yixintang Medicine Institute
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Priority to CNA2007101210327A priority Critical patent/CN101112523A/en
Publication of CN101112523A publication Critical patent/CN101112523A/en
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Abstract

The present invention relates to a traditional Chinese medicine composition for treating slow fetal growth and fetal malnutrition, which takes more than 10 Chinese herbal medicines of medicinal Indianmulberry root, membranous milkvetch root, palmleaf raspberry fruit, malaytea scurfpea fruit etc. as the raw materials. The present invention has the effects of benefiting fetus, benefiting kidney, nourishing blood and nourishing fetus. Based on the differential treatment of the traditional Chinese medicine, the invention is developed by combining the latest scientific research results with the traditional Chinese medicine. The present invention aims at providing the traditional Chinese medicine composition for treating slow fetal growth and fetal malnutrition. The present invention is characterized by accurate efficacy, safety, convenience, no toxicity or side effects and low price.

Description

A kind of Chinese medicine composition for the treatment of the diapause
Technical field
The present invention relates to a kind of Chinese medicine composition for the treatment of the diapause, is that a kind of diapause for the treatment of is the Chinese medicine composition of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Fetus is growth retardation in female abdomen, thus pregnant four May venter posterior shape with the palace body be significantly less than normal pregnancy month person, fetus still becomes the reviver on inspection, the title " diapause ".Primary disease head sees " General Treatise on the Cause and Symptoms of Diseases " and is called " non-growth of fetus ".Forefathers have the title of " pregnant retardation of growth of the fetus ", " fetal retardation " again.Primary disease is equivalent to modern medicine " fetal intrauterine growth restriction (FGR) ", or title " fetal intrauterine growth retardation (IUGR) ".The traditional Chinese medical science is divided disease type Coryza Treated by Syndrome Differentiation such as deficient qi and blood card, deficiency of spleen and stomach card clinically, obtains very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine composition for the treatment of the diapause.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by following raw materials by weight proportions:
1.5~6 parts of 1.5~6 parts of Radix Ophiopogonis of 1.5~6 parts of Poria of Radix Astragali
1.0~4 parts of 1.0~4 portions of Fructus Rubies of 1.0~4 parts of Radix Morindae Officinaliss of Rhizoma Dioscoreae
1.0~4 parts of 1.0~4 parts of Cortexs Eucommiae of 1.0~4 parts of Semen Cuscutae of Fructus Psoraleae
0.1~2 part of 0.1~2 part of Radix Boehmeriae of 0.1~2 part of Endothelium Corneum Gigeriae Galli of Semen Ziziphi Spinosae (parched).
The weight proportion of each crude drug of optimization formula of the present invention is:
2.5~3.5 parts of 2.5~3.5 parts of Radix Ophiopogonis of 2.5~3.5 parts of Poria of Radix Astragali
1.5~2.5 parts of 1.5~2.5 portions of Fructus Rubies of 1.5~2.5 parts of Radix Morindae Officinaliss of Rhizoma Dioscoreae
1.5~2.5 parts of 1.5~2.5 parts of Cortexs Eucommiae of 1.5~2.5 parts of Semen Cuscutae of Fructus Psoraleae
0.5~1.5 part of 0.5~1.5 part of Radix Boehmeriae of 0.5~1.5 part of Endothelium Corneum Gigeriae Galli of Semen Ziziphi Spinosae (parched).
The weight proportion of each crude drug of optimum formula of the present invention is:
3 parts of 3 parts of Radix Ophiopogonis of 3 parts of Poria of Radix Astragali
2 parts of 2 portions of Fructus Rubies of 2 parts of Radix Morindae Officinaliss of Rhizoma Dioscoreae
2 parts of 2 parts of Cortexs Eucommiae of 2 parts of Semen Cuscutae of Fructus Psoraleae
1 part of 1 part of Radix Boehmeriae of 1 part of Endothelium Corneum Gigeriae Galli of Semen Ziziphi Spinosae (parched).
Drug action mechanism among the present invention is as follows:
The Radix Astragali property of medicine is sweet, warm.Return lung, spleen channel.Has benefiting qi and raising yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, the effect of promoting pus discharge and tissue regeneration strengthening.Can treat the card of all Qi and blood deficiencies, as diarrhea due to hypofunction of the spleen, the cough due to deficiency of the lung, proctoptosis, uterine prolapse, spontaneous perspiration, night sweat, edema, arthralgia due to stagnation of blood, carbuncle is difficult bursts or bursts for a long time and do not hold back etc.(the 2813rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Poria property of medicine is sweet, light, and is flat.GUIXIN, spleen, lung, kidney channel.Has promoting diuresis to eliminate damp pathogen, invigorating the spleen and regulating the stomach, the effect of mind tranquilizing and the heart calming.Can treat dysuria, the edema distension, is had loose bowels at phlegm retention cough with dyspnea, vomiting, insufficiency of the spleen lack of appetite, palpitation and restlessness, insomnia forgetfulness, seminal emission nebulousurine etc.(the 2154th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Sweet, the little hardship of the Radix Ophiopogonis property of medicine is slightly cold.Return lung, stomach, heart channel.Has nourishing YIN and moistening the lung, nourishing the stomach to promote the production of body fluid, the effect of the relieving restlessness that clears away heart-fire.Can treat dryness of the lung dry cough, lung abscess, deficiency of YIN chronic cough, Tianjin wound is thirsty, quenches one's thirst, and vexed insomnia is had sore throat, the dryness of the intestine constipation, heat in blood is told nosebleed etc.(the 1430th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Rhizoma Dioscoreae property of medicine is sweet, flat.Return spleen, lung, kidney channel.Have spleen reinforcing, support lung, reinforce the kidney, the effect that benefit is smart.Can treat diarrhea due to hypofunction of the spleen, the lack of appetite edema, cough and asthma due to lung deficiency is quenched one's thirst, seminal emission, leukorrhagia, the frequent micturition of suffering from a deficiency of the kidney.Carbuncle is controlled in external, scrofula etc.(the 218th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Morindae Officinalis property of medicine suffering, sweet, tepor.Return liver, kidney channel.Has reinforcing the kidney and supporting YANG, bone and muscle strengthening, the effect of expelling wind and removing dampness.Can treat impotence due to deficiency of the kidney, the seminal emission premature ejaculation, few abdomen cold type of pain, incontinence of urine, cold womb is infertile, anemofrigid-damp arthralgia, soreness of the waist and knees, rheumatism beriberi etc.(the 709th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Fructus Rubi property of medicine is sweet, sour, tepor.Return liver, kidney channel.Has the liver and the kidney tonifying, controlling nocturnal emission with astringent drugs reducing urination, the effect that makes eye bright.Can treat impotence and premature ejaculation, emission and spermatorrhea, cold womb is infertile, and leukorrhagia is rare clearly, and the frequent micturition incontinence of urine is visual dim, early whitening of beard and hair etc.(the 3813rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Fructus Psoraleae property of medicine suffering, hardship, temperature.Return kidney, spleen channel.Has reinforcing the kidney and supporting YANG, controlling nocturnal emission with astringent drugs reducing urination, warm spleen antidiarrheal effect.Can treat the deficiency and coldness lumbago, sexual impotence spermatorrhea, the enuresis, frequent micturition, chronic diarrhea, dyspnea due to deficiency, vitiligo, alopecia areata, psoriasis etc.(the 1647th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Semen Cuscutae property of medicine suffering, sweet, flat.Return the liver,kidney,spleen warp.Have the kidney invigorating and essence nourishing, Gu nourishing the liver to improve visual acuity is the effect of tire stopping leak.Can treat soreness of waist and knee joint, seminal emission, sexual impotence, premature ejaculation, sterile, quench one's thirst, stranguria with turbid discharge, the enuresis, blurred vision tinnitus, frequent fetal movement, miscarriage is had loose bowels etc.(the 2896th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Sweet, the little suffering of the Cortex Eucommiae property of medicine, temperature.Return liver, kidney channel.Has invigorating the liver and kidney, bone and muscle strengthening, antiabortive effect.Can treat soreness of waist and knee joint, sexual impotence, frequent micturition, dribbling urination, rheumatic arthralgia, frequent fetal movement, habitual abortion etc.(the 1514th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Semen Ziziphi Spinosae (parched) property of medicine is sweet, and is flat.GUIXIN, Liver Channel.Has mind tranquilizing and the heart calming, nourishing the liver, the effect of arresting sweating.Can treat restlessness of asrhenia type and insomnia, palpitation with fear palpitation with a distress feeling, the empty spontaneous perspiration of body, night sweat etc.(the 3579th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Endothelium Corneum Gigeriae Galli property of medicine is sweet, puckery, and is flat.Return spleen, stomach, urinary bladder channel.Have strengthening the spleen and stomach, it is long-pending to help digestion, the calculi dissolving effect.Can treat food stagnation, have loose bowels, infantile malnutrition, cholelithiasis, stranguria caused by urinary stone, sand Stranguria , mass in the abdomen amenorrhea, sore throat tonsillitis, ulcerative gingivitis aphtha etc.(the 1684th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Boehmeriae property of medicine is sweet, and is cold.Return liver, the heart, urinary bladder channel.Has cooling blood for hemostasis, clearing heat and preventing abortion, diuresis, antidotal effect.Can treat spitting of blood, haematemesis, epistaxis, stranguria with blood due to the bleeding due to blood-heat, have blood in stool, metrorrhagia, purpura, frequent fetal movement, vaginal bleeding during pregnancy hematochezia, dribbling urination, carbuncle pyogenic infections from tumour or sore, worm venom etc.(the 1495th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Poria, Radix Ophiopogonis and Radix Astragali; With Rhizoma Dioscoreae, Radix Morindae Officinalis, Fructus Rubi, Fructus Psoraleae, Semen Cuscutae and the Cortex Eucommiae is ministerial drug; With Semen Ziziphi Spinosae (parched), Endothelium Corneum Gigeriae Galli and Radix Boehmeriae is adjuvant.All medicines are harmonious, and tool is good for tire kidney tonifying, the effect of the flourish tire that nourishes blood altogether.The treatment diapause has determined curative effect, has no side effect taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment diapause of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat the diapause, and the prevention of diapause is also had good effect, and the treatment diapause has determined curative effect, has no side effect taking convenience, cheap characteristics.
For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment diapause; Treatment diapause patient 25 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.One month is a course of treatment, take continuously three the course of treatment observe the curative effect.10 examples of fully recovering account for 40%, and 12 examples that take a turn for the better account for 48%, and invalid 3 examples account for 12%, and total effective rate reaches 88%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
The embodiment decoction is pressed following weight weighting raw materials:
3 parts of 3 parts of Radix Ophiopogonis of 3 parts of Poria of Radix Astragali
2 parts of 2 portions of Fructus Rubies of 2 parts of Radix Morindae Officinaliss of Rhizoma Dioscoreae
2 parts of 2 parts of Cortexs Eucommiae of 2 parts of Semen Cuscutae of Fructus Psoraleae
1 part of 1 part of Radix Boehmeriae of 1 part of Endothelium Corneum Gigeriae Galli of Semen Ziziphi Spinosae (parched).
Preparation method is to get the above-mentioned raw materials medicine to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5~2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1~1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment diapause that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.One month is a course of treatment.

Claims (3)

1. Chinese medicine composition for the treatment of the diapause is characterized in that it is made by following raw materials by weight proportions:
1.5~6 parts of 1.5~6 parts of Radix Ophiopogonis of 1.5~6 parts of Poria of Radix Astragali
1.0~4 parts of 1.0~4 portions of Fructus Rubies of 1.0~4 parts of Radix Morindae Officinaliss of Rhizoma Dioscoreae
1.0~4 parts of 1.0~4 parts of Cortexs Eucommiae of 1.0~4 parts of Semen Cuscutae of Fructus Psoraleae
0.1~2 part of 0.1~2 part of Radix Boehmeriae of 0.1~2 part of Endothelium Corneum Gigeriae Galli of Semen Ziziphi Spinosae (parched).
2. a kind of Chinese medicine composition for the treatment of the diapause according to claim 1, wherein the weight proportion of each crude drug is:
2.5~3.5 parts of 2.5~3.5 parts of Radix Ophiopogonis of 2.5~3.5 parts of Poria of Radix Astragali
1.5~2.5 parts of 1.5~2.5 portions of Fructus Rubies of 1.5~2.5 parts of Radix Morindae Officinaliss of Rhizoma Dioscoreae
1.5~2.5 parts of 1.5~2.5 parts of Cortexs Eucommiae of 1.5~2.5 parts of Semen Cuscutae of Fructus Psoraleae
0.5~1.5 part of 0.5~1.5 part of Radix Boehmeriae of 0.5~1.5 part of Endothelium Corneum Gigeriae Galli of Semen Ziziphi Spinosae (parched).
3. a kind of Chinese medicine composition for the treatment of the diapause according to claim 1, wherein the weight proportion of each crude drug is:
3 parts of 3 parts of Radix Ophiopogonis of 3 parts of Poria of Radix Astragali
2 parts of 2 portions of Fructus Rubies of 2 parts of Radix Morindae Officinaliss of Rhizoma Dioscoreae
2 parts of 2 parts of Cortexs Eucommiae of 2 parts of Semen Cuscutae of Fructus Psoraleae
1 part of 1 part of Radix Boehmeriae of 1 part of Endothelium Corneum Gigeriae Galli of Semen Ziziphi Spinosae (parched).
CNA2007101210327A 2007-08-29 2007-08-29 Chinese traditional medicine composition for treating embryonic diapause Pending CN101112523A (en)

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Application Number Priority Date Filing Date Title
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105412799A (en) * 2015-12-27 2016-03-23 鹿哲维 Traditional Chinese medicine composition for treating blood-heat type atrophied fetus
CN105477122A (en) * 2015-12-27 2016-04-13 鹿哲维 Traditional Chinese medicine composition for treating blood cold type retarded growth of fetuses
CN105727146A (en) * 2016-04-11 2016-07-06 王华荣 Traditional Chinese medicine for treating embryonic diapause

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105412799A (en) * 2015-12-27 2016-03-23 鹿哲维 Traditional Chinese medicine composition for treating blood-heat type atrophied fetus
CN105477122A (en) * 2015-12-27 2016-04-13 鹿哲维 Traditional Chinese medicine composition for treating blood cold type retarded growth of fetuses
CN105727146A (en) * 2016-04-11 2016-07-06 王华荣 Traditional Chinese medicine for treating embryonic diapause

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Open date: 20080130