CN105727146A - Traditional Chinese medicine for treating embryonic diapause - Google Patents

Traditional Chinese medicine for treating embryonic diapause Download PDF

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CN105727146A
CN105727146A CN201610225746.1A CN201610225746A CN105727146A CN 105727146 A CN105727146 A CN 105727146A CN 201610225746 A CN201610225746 A CN 201610225746A CN 105727146 A CN105727146 A CN 105727146A
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radix
chinese medicine
semen
fructus
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王华荣
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Abstract

The invention discloses a traditional Chinese medicine for treating embryonic diapauses.The traditional Chinese medicine comprises, by weight, 12-18 parts of radix bupleuri, 18-25 parts of radix angelica sinensis bodies, 5-8 parts of paenoiae alba, 8-12 parts of arillus longan, 13-18 parts of dioscorea opposita thunb, 8-12 parts of rehmannia glutinosa, 10-15 parts of largehead atractylodes rhizome, 5-8 parts of fructus amomi, 5-8 parts of withered radix scutellariae, 8-12 parts of radix codonopsis, 5-8 parts of cortex eucommiae, 8-12 parts of herba taxilli, 5-8 parts of fructus corni meat, 8-12 parts of semen nelumbinis meat, 8-12 parts of Chinese date kernels, 4-6 parts of donkey-hide glue, 0.8-1.5 parts of cornu cervi pantotrichum pieces, 5-8 parts of semen cuscutae, 5-8 parts of roasted radix glycyrrhizae and 12 parts of mulberries.The traditional Chinese medicine is capable of tonifying the spleen and the stomach, regulating the liver and qi and nourishing yin and blood so that a fetus can be nourished by reasonably matching the multiple types of medical materials.

Description

The Chinese medicine composition for the treatment of diapause
Technical field
The present invention relates to tcm field, particularly relate to a kind of Chinese medicine composition treating diapause.
Background technology
Diapause is names of disease of tcm, and also known as non-growth of fetus, gestation retardation of growth of the fetus etc., doctor trained in Western medicine is referred to as tire Youngster's intrauterine growth retardation, FGR etc., after being pregnant four or five months, its abdomen shape increases with palace body It is significantly less than normal pregnancy month, fetal survival and growth retardation person, general through medical treatment meticulously, can continue Continuous smooth normal development, growth, term labor.If in time diagnosis and treatment or recuperate under medical treatment improper, then can affect tire Youngster's growth promoter, may result in and expired do not produce, the most then retention of dead fetus.Primary disease directly affects neonate quality, Therefore diagnose early and treat, otherwise congenital defect, affect posteriori physical ability and intelligence.
At present, on think in this disease doctor trained in Western medicine affect with the inherited genetic factors of anemia of pregnant woman relatively big, with anemia of pregnant woman's pregestational weight, During gestation, age and tire parity are correlated with.If pregestational weight is less than 54kg, during gestation, body weight is too small or excessive, Fetal intrauterine growth retardation chance is occurred all to increase.Maternal nutritional is bad, and particularly protein and energy supplies Should be not enough, long-term hypoxemia or oxygen transport inferior capabilities, gestation merging kidney disease, severe anemia, Adverse cardiac, pregnancy induced hypertension syndrome, the various chronic vascular disease such as chronic hypertension, impact Palace and placental blood flow and function, cause fetal malnutrition, immune disease, endocrinopathy, infection Embryo growth and development all can be affected during property disease.
At present, the treatment general recommendations of this disease is taked left lateral position to have a rest by doctor trained in Western medicine, to promote in utero blood Circulation.Edible high protein diet, strengthens nutrition, is interrupted oxygen uptake.Additionally, such as stop some bad habits, Such as smoking, drink.Above method is daily Opsonizing method, and effect is difficult to expect.To tire in doctor trained in Western medicine The Drug therapy of youngster's growth retardation typically uses heparin 25mg to be dissolved in low molecular dextran solution In 500ml, dead point once a day, 7d is a course for the treatment of.To dredge microcirculation, improve placental function.Or Person compound amino acid solution 100ml, intravenous injection, 1/d, 7d are a course for the treatment of.But, these medicines are controlled Treat and also cure the symptoms, not the disease, it is impossible to fundamentally treating, therapeutic effect is the most undesirable, and has Side effect.
In the traditional Chinese medical science, diapause is had deep research, in " the dry time of General Treatise on the Cause and Symptoms of Diseases retardation of growth of fetus " just Have: " tire born of the same parents, vim and vigour money is supported, if vim and vigour are deficient, the dirty cold person of born of the same parents, the dry Fu Buchang that withers of tire then nebula. Its strong youngster does not rotates in tire, though life is full, also can not give birth to, and is that it is waited also.And tire is dry at interior flaccidity, How dead its tire is." " Chen Su Buddhist nunnery Gynecology Supplement solution " think that primary disease is relevant with emotional factors.Book is said: " as Be pregnent melancholy not understanding, and cloudy blood attenuation, tire is dry and wither ".The traditional Chinese medical science is it is believed that the principal pathogenetic machine of primary disease Reason is that parent natural endowment is weak, and internal organs vim and vigour are lost, or pregnant rear insufficiency of vital energy and blood supports its tire with honor, then causes Retardation of growth of fetus, also has because father's gas is frail, and man's essence is not strengthened, and nausea is unreal and cause person.But, owing to many-side is former Cause, the prescription effect of current Chinese traditional treatment diapause also tends to unsatisfactory.
Summary of the invention
It is an object of the invention to for the above-mentioned problems in the prior art, it is provided that one treats retardation of growth of fetus not Long Chinese medicine composition, it is possible to effectively treat diapause, makes fetal development good, subjects born at term, and Have no side effect.
For achieving the above object, the present invention adopts the following technical scheme that
A kind of Chinese medicine composition treating diapause, wherein, comprises the crude drug of following weight portion:
Radix Bupleuri 12-18, Radix Angelicae Sinensis body 18-25, Radix Paeoniae Alba 5-8, Arillus Longan 8-12, Rhizoma dioscoreae 13-18, Radix Rehmanniae Preparata 8-12, Rhizoma Atractylodis Macrocephalae preparata 10-15, Fructus Amomi 5-8, withered and yellow a kind of reed mentioned in ancient books 5-8, Radix Codonopsis 8-12, Cortex Eucommiae 5-8, Mulberry Parasitic 8-12, Fructus Corni 5-8, Semen Nelumbinis 8-12, Semen Ziziphi Spinosae 8-12, Colla Corii Asini 4-6, piece of antler 0.8-1.5, Semen Cuscutae 5-8, Radix Glycyrrhizae Preparata 5-8 and Fructus Mori 8-12.
Preferably, the Chinese medicine composition of described treatment diapause, wherein, comprise following weight portion Crude drug:
Radix Bupleuri 15, Radix Angelicae Sinensis body 20, Radix Paeoniae Alba 6, Arillus Longan 10, Rhizoma dioscoreae 15, Radix Rehmanniae Preparata 10, Jiao Bai Art 12, Fructus Amomi 6, withered and yellow a kind of reed mentioned in ancient books 6, Radix Codonopsis 10, the Cortex Eucommiae 6, Herba Taxilli 10, Fructus Corni 6, Semen Nelumbinis 10, Semen Ziziphi Spinosae 10, Colla Corii Asini 5, piece of antler 1, Semen Cuscutae 6, Radix Glycyrrhizae Preparata 6 and Fructus Mori 9.
The present invention at least includes following beneficial effect: the present invention utilizes the traditional Chinese medical science five elements and dialectical theory, it is believed that Gestation this QI and blood of nausea supports it, and retardation of growth of the fetus person, by the void of taste, changes source not enough, disgruntled adverse flow of liver-QI blood Uncomfortable caused.The present invention is by by kinds of traditional Chinese medicines reasonable compatibility, and spleen invigorating reason stomach, regulating liver and qi, YIN nourishing are supported Blood, makes fetus to support.
The present invention, according to clinical 100 example patient view statistics, is a course for the treatment of according to every 5-7 agent, with Every day, the consumption of potion took 2-5 the course for the treatment of continuously, and cure rate reaches 93%.
Part is embodied by the further advantage of the present invention, target and feature by description below, and part also will By the research of the present invention and practice are understood by the person skilled in the art.
Detailed description of the invention
Below the present invention is elaborated, to make those of ordinary skill in the art refer to energy after this specification Enough implement according to this.
A kind of Chinese medicine composition treating diapause, wherein, comprises the crude drug of following weight portion: bavin Recklessly 12-18, Radix Angelicae Sinensis body 18-25, Radix Paeoniae Alba 5-8, Arillus Longan 8-12, Rhizoma dioscoreae 13-18, Radix Rehmanniae Preparata 8-12, Rhizoma Atractylodis Macrocephalae preparata 10-15, Fructus Amomi 5-8, withered and yellow a kind of reed mentioned in ancient books 5-8, Radix Codonopsis 8-12, Cortex Eucommiae 5-8, Herba Taxilli 8-12, Fructus Corni 5-8, Semen Nelumbinis 8-12, Semen Ziziphi Spinosae 8-12, Colla Corii Asini 4-6, piece of antler 0.8-1.5, Semen Cuscutae 5-8, Radix Glycyrrhizae Preparata 5-8 and Fructus Mori 8-12.Radix Angelicae Sinensis as when after palpus of going back use be used as medicine.Cortex Eucommiae parch Rear use, is Cortex Eucommiae (parched), it is possible to reduce cold and cool property, relaxes the property of medicine.
The present invention utilizes the traditional Chinese medical science five elements and dialectical theory, it is believed that gestation this QI and blood of nausea supports it, retardation of growth of the fetus Person, by the void of taste, changes source not enough, caused by disgruntled adverse flow of liver-QI blood dyscrasia.
The concrete pharmacology of the present invention is:
Radix Bupleuri, solves the strongly fragrant gas of liver；
Radix Angelicae Sinensis body, nourishes blood, enriches blood；
Radix Paeoniae Alba, nourish blood yin fluid astringing；
Arillus Longan, strengthening spleen and nourishing blood；
Rhizoma dioscoreae, invigorating the spleen and benefiting QI, nourishing blood and preventing abortion；
Radix Rehmanniae Preparata, nourishing the blood and yin, vital essence replenishing and marrow benifiting；
Rhizoma Atractylodis Macrocephalae preparata, replenishing QI to invigorate the spleen, antiabortive；
Fructus Amomi, preventing or arresting vomiting, antiabortive；
Withered and yellow a kind of reed mentioned in ancient books, clearing heat and preventing abortion；
Radix Codonopsis, replenishing QI to invigorate the spleen, nourishes blood；
The Cortex Eucommiae, invigorating the liver and kidney, antiabortive；
Herba Taxilli, invigorating the liver and kidney, nourishing blood and preventing abortion；
Fructus Corni, liver and kidney tonifying；
Semen Nelumbinis, the blood that nourishes heart, relieving restlessness；
Semen Ziziphi Spinosae, nourishes blood and allays excitement；
Colla Corii Asini, enriches blood, stops blooding；
Piece of antler, invigorating primordial QI consolidates；
Semen Cuscutae, YANG invigorating tonifying YIN；
Radix Glycyrrhizae Preparata, invigorating the spleen and replenishing QI；
Fructus Mori, enrich blood, kidney tonifying dirty.
The present invention manages stomach, regulating liver and qi, invigorating QI and blood by above kinds of traditional Chinese medicines reasonable compatibility, spleen invigorating, Make fetus to support, effectively treat diapause, make intrauterine growth normal, mature production.
Embodiment 1
1, Radix Bupleuri 15 grams, Radix Angelicae Sinensis body 20 grams, Radix Paeoniae Alba 6 grams, Arillus Longan 10 grams, Rhizoma dioscoreae are weighed 15 grams, 10 grams of Radix Rehmanniae Preparata, Rhizoma Atractylodis Macrocephalae preparata 12 grams, Fructus Amomi 6 grams, withered and yellow a kind of reed mentioned in ancient books 6 grams, Radix Codonopsis 10 grams, Du Secondary 6 grams, Herba Taxilli 10 grams, Fructus Corni 6 grams, Semen Nelumbinis 10 grams, Semen Ziziphi Spinosae 10 grams, 5 grams of Colla Corii Asini, Piece of antler 1 gram, Semen Cuscutae 6 grams, Radix Glycyrrhizae Preparata 6 grams and 9 grams of Fructus Mori.
2, the water soaking of 1.5 times of volumes of addition 20 minutes, boil rear slow fire and boil 20-25 minute, filter Go out medicinal liquid, obtain the first filtrate；
3, in medicinal residues, rejoin isopyknic water, boil rear slow fire and boil 30-35 minute, leach medicine Liquid obtains the second filtrate；
First filtrate and the second filtrate being mixed, every day, potion, took for every dose at twice, and 5 doses is one The course for the treatment of, take 4 courses for the treatment of continuously.
Patient Wang, female, 27 years old, when pregnant 30 weeks, palace height, abdominal circumference and anemia of pregnant woman's body weight were all significantly less than Corresponding pregnant Zhou Zhibiao, is diagnosed as diapause through tcm clinical practice.2 treatments are taken according to above therapeutic scheme After journey, every taking stopgap measures is obviously improved, close to normal, after continuing to take 2 courses for the treatment of every take stopgap measures normal, tire Youngster's growth promoter is normal, subjects born at term when 39 weeks.
Embodiment 2
1, Radix Bupleuri 18 grams, Radix Angelicae Sinensis body 22 grams, Radix Paeoniae Alba 5 grams, Arillus Longan 12 grams, Rhizoma dioscoreae 18 grams, 12 grams of Radix Rehmanniae Preparata, Rhizoma Atractylodis Macrocephalae preparata 15 grams, Fructus Amomi 5 grams, withered and yellow a kind of reed mentioned in ancient books 7 grams, Radix Codonopsis 12 grams, the Cortex Eucommiae 8 grams, Herba Taxilli 9 grams, Fructus Corni 7 grams, Semen Nelumbinis 12 grams, Semen Ziziphi Spinosae 9 grams, 6 grams of Colla Corii Asini, piece of antler 1.5 Gram, Semen Cuscutae 7 grams, Radix Glycyrrhizae Preparata 8 grams and 10 grams of Fructus Mori.
2, the water soaking of 2-3 times of volume of addition 30 minutes, boil rear slow fire and boil 25-30 minute, filter Go out medicinal liquid, obtain the first filtrate；
3, in medicinal residues, rejoin the water of 1-2 times of volume, boil rear slow fire and boil 30-35 minute, filter Go out medicinal liquid and obtain the second filtrate；
4, the first filtrate and the second filtrate being mixed, every day, potion, took for every dose at twice, and 7 doses is one The individual course for the treatment of, take 4 courses for the treatment of continuously.
Patient's chapter, female, 31 years old, when pregnant 28 weeks, palace height, abdominal circumference and anemia of pregnant woman's body weight were all significantly less than Corresponding pregnant Zhou Zhibiao, is diagnosed as diapause through tcm clinical practice.2 treatments are taken according to above therapeutic scheme After journey, every taking stopgap measures is obviously improved, close to normal, after continuing to take 2 courses for the treatment of every take stopgap measures normal, tire Youngster's growth promoter is normal, subjects born at term when 40 weeks.
Use Chinese medicine composition of the present invention that 100 example diapause patients are treated, control through clinic Treat, cure 93 examples, equal 39-41 week subjects born at term, and newborn outcome is all more than 7 points, cure rate Reach 93%.
The foregoing is only embodiment of the present invention, not thereby limit the scope of the claims of the present invention, all It is the equivalent structure utilizing description of the invention content to be made or equivalence flow process conversion, or directly or indirectly transports It is used in other correlative technology fields, is included in the scope of patent protection of the present invention.

Claims (2)

1. the Chinese medicine composition treating diapause, it is characterised in that comprise the former of following weight portion Material medicine:
Radix Bupleuri 12-18, Radix Angelicae Sinensis body 18-25, Radix Paeoniae Alba 5-8, Arillus Longan 8-12, Rhizoma dioscoreae 13-18, Radix Rehmanniae Preparata 8-12, Rhizoma Atractylodis Macrocephalae preparata 10-15, Fructus Amomi 5-8, withered and yellow a kind of reed mentioned in ancient books 5-8, Radix Codonopsis 8-12, Cortex Eucommiae 5-8, Mulberry Parasitic 8-12, Fructus Corni 5-8, Semen Nelumbinis 8-12, Semen Ziziphi Spinosae 8-12, Colla Corii Asini 4-6, piece of antler 0.8-1.5, Semen Cuscutae 5-8, Radix Glycyrrhizae Preparata 5-8 and Fructus Mori 8-12.
2. the Chinese medicine composition treating diapause as claimed in claim 1, it is characterised in that comprise The crude drug of following weight portion:
Radix Bupleuri 15, Radix Angelicae Sinensis body 20, Radix Paeoniae Alba 6, Arillus Longan 10, Rhizoma dioscoreae 15, Radix Rehmanniae Preparata 10, Jiao Bai Art 12, Fructus Amomi 6, withered and yellow a kind of reed mentioned in ancient books 6, Radix Codonopsis 10, the Cortex Eucommiae 6, Herba Taxilli 10, Fructus Corni 6, Semen Nelumbinis 10, Semen Ziziphi Spinosae 10, Colla Corii Asini 5, piece of antler 1, Semen Cuscutae 6, Radix Glycyrrhizae Preparata 6 and Fructus Mori 9.
CN201610225746.1A 2016-04-11 2016-04-11 Traditional Chinese medicine for treating embryonic diapause Pending CN105727146A (en)

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1706463A (en) * 2005-05-23 2005-12-14 陕西关爱制药有限公司 Medicine for treating women's habitual abortion and threatened abortion
CN101112523A (en) * 2007-08-29 2008-01-30 北京艺信堂医药研究所 Chinese traditional medicine composition for treating embryonic diapause
CN103784915A (en) * 2013-06-03 2014-05-14 吕汉 Female qi-blood regulating prescription
CN104510970A (en) * 2014-12-02 2015-04-15 广东聚智诚科技有限公司 Use of traditional Chinese medicine preparation in preparation of drug for treatment of habitual abortion
CN104623502A (en) * 2015-02-05 2015-05-20 张祺 Traditional Chinese medicine composition for calming fetus

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1706463A (en) * 2005-05-23 2005-12-14 陕西关爱制药有限公司 Medicine for treating women's habitual abortion and threatened abortion
CN101112523A (en) * 2007-08-29 2008-01-30 北京艺信堂医药研究所 Chinese traditional medicine composition for treating embryonic diapause
CN103784915A (en) * 2013-06-03 2014-05-14 吕汉 Female qi-blood regulating prescription
CN104510970A (en) * 2014-12-02 2015-04-15 广东聚智诚科技有限公司 Use of traditional Chinese medicine preparation in preparation of drug for treatment of habitual abortion
CN104623502A (en) * 2015-02-05 2015-05-20 张祺 Traditional Chinese medicine composition for calming fetus

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