CN101095901A - Chinese traditional medicine composition for treating nephrotic syndrome - Google Patents
Chinese traditional medicine composition for treating nephrotic syndrome Download PDFInfo
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- CN101095901A CN101095901A CNA2007101183160A CN200710118316A CN101095901A CN 101095901 A CN101095901 A CN 101095901A CN A2007101183160 A CNA2007101183160 A CN A2007101183160A CN 200710118316 A CN200710118316 A CN 200710118316A CN 101095901 A CN101095901 A CN 101095901A
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Abstract
The invention relates to a Chinese medicinal composition for treating nephrotic syndrome which is prepared from more than ten kinds of Chinese medicinal herbs including coix seed, pinellia tuber, flatstem milkvetch seed and areca catecha. The medicament has the advantages of assured curative effect, safe and convenient application, no toxic and side effects, and low price.
Description
Technical field
The present invention relates to treat a kind of Chinese medicine composition of nephrotic syndrome, is that a kind of nephrotic syndrome for the treatment of is the Chinese medicine composition of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
(Nephrotic Syndrome NS) is proposed in 1932 by foreign scholar Hriction nephrotic syndrome.In order to summarize one group of card Hou Qun in the renal glomerular disease, it accounts for 70%～90% in child's renal glomerular disease, also account for 20%～30% in the adult.All have clinically a large amount of albuminuria (every day＞3.5g), hypoproteinemia (albumin＜30g/L), obviously edema, hyperlipemia (characteristic person such as serum cholesterol＞6.5mmol/L) can examine and is nephrotic syndrome.Nephrotic syndrome is at the clinical branch that constitutional and Secondary cases are arranged.Primary nephrotic syndrome (PNS) refers to by the sick causer of primary glomerular, adult's the most nephrotic syndrome of 2/3 and child is constitutional, pathological change is mainly the minute lesion type, and part is changes such as film, proliferative, film proliferative and focal nephrosclerosis.The patient of morbidity more than 45 years old, may be except must noting with malignant tumor, with Hodgkin, membranous nephropathy accompanies by solid tumors such as lung, breast, gastrointestinal etc. as minimal change nephropathy.The Secondary cases nephrotic syndrome is meant and is secondary to the whole body other diseases or by specificity cause of disease causer, as medicine mediation property nephrotic syndrome, the nephrotic syndrome that causes by allergy, poisoning, immunoreation, the nephrotic syndrome that causes by infection such as antibacterial, virus, parasites, nephrotic syndrome due to tumor and the heredity, nephrotic syndrome that metabolic disease caused such as systemic disease such as connective tissue, anaphylactoid purpura and diabetes, amyloidosis etc.Nephrotic syndrome 1/3 and the child 10% who is grown up can be by above-mentioned cause of disease secondary.Disease categories such as " edema " of nephrotic syndrome ownership Chinese medicine, " asthenia ".The clinical manifestation of primary disease is: a large amount of albuminuria (＞3.5g/24h), hypoproteinemia (albumin＜30g/L), obviously edema, hyperlipemia.The nephrotic syndrome course of disease is long, the relapse rate height, and simple western medicine treatment often can not obtain ideal effect, some intractable nephrotic syndromes especially, clinical treatment is often more thorny.And adopt the comprehensive method treatment nephrotic syndrome of Chinese and western medicine, and not only enlarged the treatment approach, and clinical confirmation obtained gratifying curative effect, be considered to comparatively ideal therapeutic scheme.
The traditional Chinese medical science is divided disease type Coryza Treated by Syndrome Differentiation such as retention of damp-heat in the interior, the wet dipping of water, edema due to YANG-insufficiency, stagnation of dampness due to deficiency of the spleen, edema due to wind pathogen Xiang Bo clinically, obtains very good effect.Therefore invent a kind of not only safety but also effective Chinese medicine preparation, be significant.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine composition for the treatment of nephrotic syndrome.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by the following weight proportion raw material:
1.5～6 parts of 1.5～6 parts of Rhizoma Atractylodis Macrocephalae (parched)s of 1.5～6 parts of Semen Coiciss of Rhizoma Alismatis
1.0～4 parts of 1.0～4 parts of Radix Codonopsis of 1.0～4 parts of Radix Rehmanniae Preparata of Radix Curcumae
0.1～2 part of 1.0～4 parts of Pericarpium Citri Reticulatae of 1.0～4 parts of Semen Astragali Complanatis of Rhizoma Dioscoreae
0.1～1 part of 0.1～2 part of Rhizoma Pinelliae Preparatum of 0.1～2 part of Pericarpium Arecae of Rhizoma Atractylodis.
The weight proportion of each raw material of optimization formula of the present invention is:
2.5～3.5 parts of 2.5～3.5 parts of Rhizoma Atractylodis Macrocephalae (parched)s of 2.5～3.5 parts of Semen Coiciss of Rhizoma Alismatis
1.5～2.5 parts of 1.5～2.5 parts of Radix Codonopsis of 1.5～2.5 parts of Radix Rehmanniae Preparata of Radix Curcumae
0.5～1.5 part of 1.5～2.5 parts of Pericarpium Citri Reticulatae of 1.5～2.5 parts of Semen Astragali Complanatis of Rhizoma Dioscoreae
0.3～0.7 part of 0.5～1.5 part of Rhizoma Pinelliae Preparatum of 0.5～1.5 part of Pericarpium Arecae of Rhizoma Atractylodis.
The weight proportion of each raw material of optimum formula of the present invention is:
3 parts of 3 parts of Rhizoma Atractylodis Macrocephalae (parched)s of 3 parts of Semen Coiciss of Rhizoma Alismatis
2 parts of 2 parts of Radix Codonopsis of 2 parts of Radix Rehmanniae Preparata of Radix Curcumae
1 part of 2 parts of Pericarpium Citri Reticulatae of 2 parts of Semen Astragali Complanatis of Rhizoma Dioscoreae
0.5 part of 1 part of Rhizoma Pinelliae Preparatum of 1 part of Pericarpium Arecae of Rhizoma Atractylodis.
Drug action mechanism among the present invention is as follows:
The Rhizoma Alismatis property of medicine is sweet, light, and is cold.Return kidney, urinary bladder channel.Have promoting diuresis to eliminate damp pathogen, treating stranguria effect expels the heat-evil.Can treat dysuria, the puckery pain of pyretic stranguria, the edema distension is had loose bowels, dizziness due to fluid-retention, seminal emission etc.(the 2067th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Semen Coicis property of medicine is sweet, light, is slightly cold.Return spleen, stomach, lung meridian.Has the dampness removing spleen invigorating, arthralgia relieving by relaxing muscles and tendons, the effect of clearing away heat and discharging pus.Can treat edema, beriberi, dribbling urination, damp-warm diseases is had loose bowels, leukorrhagia, rheumatic arthralgia, the contracture of muscle arteries and veins, lung abscess, acute appendicitis, verruca plana etc.(the 3725th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Rhizoma Atractylodis Macrocephalae (parched) hardship, sweet, temperature.Return spleen, stomach warp.Has invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive effect.Can treat the weak of deficiency-weakness of spleen-QI, lack of appetite abdominal distention is had loose bowels, constipation, the dysuria of fluid-retention stagnating in the interior, edema, dizziness due to fluid-retention, cold-damp numbness, general pain, spontaneous sweating due to deficiency of QI, frequent fetal movement etc.(the 945th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Curcumae property of medicine suffering, hardship, cold.GUIXIN, liver, gallbladder meridian.Has promoting blood circulation and stopping pain, promoting QI circulation for relieving depression, the removing heat from blood that clears away heart-fire, the effect of function of gallbladder promoting.Can treat all pains of breast abdomen side of body rib, dysmenorrhea ， mass in the abdomen, the calentura coma, demented, spit blood epistaxis, stranguria with blood, sand Stranguria, jaundice etc.(the 1855th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Rehmanniae Preparata sweet in the mouth, slightly warm in nature.Have nourishing YIN and supplementing blood, beneficial essence is filled out the effect of marrow.Can treat soreness of the waist and knees, osteopyrexia and fever, the night sweat seminal emission, interior-heat is quenched one's thirst, severe palpitation, menoxenia, metrostaxis, dizzy, tinnitus, early whitening of beard and hair, anemia etc.(the 197th page of chief editor such as the firm Xiao Ying of party " Chinese medicine and health food development and exploitation " People's Health Publisher).
The Radix Codonopsis property of medicine is sweet, and is flat.Return spleen, lung meridian.Has strengthening the spleen and tonifying the lung, the effect of supplementing QI for promoting the production of body fluid.Can treat weakness of the spleen and stomach, anorexia and loose stool, limbs fatigue, the deficiency of the lung is breathed with cough, the spontaneous perspiration of breathing hard, deficiency of both QI and blood etc.(the 2579th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Rhizoma Dioscoreae property of medicine is sweet, flat.Return spleen, lung, kidney channel.Have spleen reinforcing, support lung, reinforce the kidney, the effect that benefit is smart.Can treat diarrhea due to hypofunction of the spleen, the lack of appetite edema, cough and asthma due to lung deficiency is quenched one's thirst, seminal emission, leukorrhagia, the frequent micturition of suffering from a deficiency of the kidney.Carbuncle is controlled in external, scrofula etc.(the 218th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Semen Astragali Complanati property of medicine is sweet, temperature.Return liver, kidney channel.Has tonifying the kidney to consolidate the essence, the effect of liver-benefiting eye-brightening.Can treat deficiency of the liver and kindey, the lumbago knee joint is soft, the seminal emission premature ejaculation, and frequent micturition is lost drop, the nebulousurine leukorrhagia, tinnitus is dizzy, and eyes is dim-sighted etc.(the 1519th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Pericarpium Citri Reticulatae property of medicine suffering, hardship, temperature.Return spleen, stomach, lung meridian.Having in the accent of regulating the flow of vital energy stopping nausea and vomiting by lowering the adverse flow of QI, the effect of drying dampness to eliminate phlegm.It is full vexed to treat chest and diaphragm, abdominal distention, anorexia, vomiting, hiccup; Cough with copious phlegm.Acute mastitis from the beginning of etc.(the 1668th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Rhizoma Atractylodis property of medicine suffering, hardship, temperature.Return spleen, stomach, Liver Channel.Have drying damp and strengthening spleen, wind-damp dispelling, the effect that makes eye bright.Can treat the spleen and stomach being stranded by dampness, the asthenia drowsiness, feeling of stuffiness in chest abdominal distention, inappetence, vomiting is had loose bowels, phlegm retention, damp-edema, the exterior syndrome folder is wet, a heavy sensation of the body pain, arthromyodynia domination of damp pathogen, podomere are ached and are being weighed, and flaccidity is sprained, nyctalopia etc.(the 1485th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Pericarpium Arecae property of medicine suffering, tepor.Return spleen, stomach, large intestine, small intestine meridian.Has therapeutic method to keep the adverse QI flowing downwards alleviating distention in middle-JIAO, the effect of line water detumescence.It is vexed to treat breast abdominal distention, edema, beriberi, dysuria etc.(the 178th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Rhizoma Pinelliae Preparatum property of medicine suffering, temperature, poisonous.Return spleen, stomach, lung meridian.Has drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, the effect of dissolving lump and resolving mass.Can treat the cough with asthma abundant expectoration, vomiting regurgitation, feeling of oppression and fullness in the chest and epigastrium, pain is dizzy, uneasy sleeping at night, goiter sucutaneous nodule, swollen ulcer drug etc.(the 1073rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Semen Coicis, Rhizoma Pinelliae Preparatum, Rhizoma Atractylodis Macrocephalae (parched) and Rhizoma Alismatis; With Rhizoma Atractylodis, Radix Curcumae, Rhizoma Dioscoreae, Radix Rehmanniae Preparata, Radix Codonopsis and Semen Astragali Complanati is ministerial drug; With Pericarpium Citri Reticulatae and Pericarpium Arecae is adjuvant.All medicines are harmonious, and tool is drying damp and strengthening spleen altogether, the effect of QI invigorating row water.The treatment nephrotic syndrome has determined curative effect, has no side effect taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of Pharmacopoeia of People's Republic of China, utilizes the comprehensive function treatment nephrotic syndrome of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat nephrotic syndrome, and the prevention of nephrotic syndrome is also had good effect, and the treatment nephrotic syndrome has determined curative effect, has no side effect taking convenience, cheap characteristics.
For showing medicine of the present invention, as follows through clinical test results to treatment management of Idiopathic Nephrotic Syndrome in Children effect; Treatment nephrotic syndrome patient 19 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Three months is a course of treatment, take continuously three the course of treatment observe the curative effect.8 examples of fully recovering account for 42.11%, and 8 examples that take a turn for the better account for 42.11%, and invalid 3 examples account for 15.79%, and total effective rate reaches 84.22%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
The embodiment decoction takes by weighing raw material by following weight:
3 parts of 3 parts of Rhizoma Atractylodis Macrocephalae (parched)s of 3 parts of Semen Coiciss of Rhizoma Alismatis
2 parts of 2 parts of Radix Codonopsis of 2 parts of Radix Rehmanniae Preparata of Radix Curcumae
1 part of 2 parts of Pericarpium Citri Reticulatae of 2 parts of Semen Astragali Complanatis of Rhizoma Dioscoreae
0.5 part of 1 part of Rhizoma Pinelliae Preparatum of 1 part of Pericarpium Arecae of Rhizoma Atractylodis.
Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5～2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1～1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment nephrotic syndrome that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Three months is a course of treatment.
Claims (3)
1, a kind of Chinese medicine composition of treatment nephrotic syndrome is characterized in that it is made by the following weight proportion raw material:
1.5～6 parts of 1.5～6 parts of Rhizoma Atractylodis Macrocephalae (parched)s of 1.5～6 parts of Semen Coiciss of Rhizoma Alismatis
1.0～4 parts of 1.0～4 parts of Radix Codonopsis of 1.0～4 parts of Radix Rehmanniae Preparata of Radix Curcumae
0.1～2 part of 1.0～4 parts of Pericarpium Citri Reticulatae of 1.0～4 parts of Semen Astragali Complanatis of Rhizoma Dioscoreae
0.1～1 part of 0.1～2 part of Rhizoma Pinelliae Preparatum of 0.1～2 part of Pericarpium Arecae of Rhizoma Atractylodis.
2, a kind of Chinese medicine composition of treatment nephrotic syndrome according to claim 1, wherein the weight proportion of each raw material is:
2.5～3.5 parts of 2.5～3.5 parts of Rhizoma Atractylodis Macrocephalae (parched)s of 2.5～3.5 parts of Semen Coiciss of Rhizoma Alismatis
1.5～2.5 parts of 1.5～2.5 parts of Radix Codonopsis of 1.5～2.5 parts of Radix Rehmanniae Preparata of Radix Curcumae
0.5～1.5 part of 1.5～2.5 parts of Pericarpium Citri Reticulatae of 1.5～2.5 parts of Semen Astragali Complanatis of Rhizoma Dioscoreae
0.3～0.7 part of 0.5～1.5 part of Rhizoma Pinelliae Preparatum of 0.5～1.5 part of Pericarpium Arecae of Rhizoma Atractylodis.
3, a kind of Chinese medicine composition of treatment nephrotic syndrome according to claim 1, wherein the weight proportion of each raw material is:
3 parts of 3 parts of Rhizoma Atractylodis Macrocephalae (parched)s of 3 parts of Semen Coiciss of Rhizoma Alismatis
2 parts of 2 parts of Radix Codonopsis of 2 parts of Radix Rehmanniae Preparata of Radix Curcumae
1 part of 2 parts of Pericarpium Citri Reticulatae of 2 parts of Semen Astragali Complanatis of Rhizoma Dioscoreae
0.5 part of 1 part of Rhizoma Pinelliae Preparatum of 1 part of Pericarpium Arecae of Rhizoma Atractylodis.
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| Application Number | Priority Date | Filing Date | Title |
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| CNA2007101183160A CN101095901A (en) | 2007-07-05 | 2007-07-05 | Chinese traditional medicine composition for treating nephrotic syndrome |
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| CNA2007101183160A CN101095901A (en) | 2007-07-05 | 2007-07-05 | Chinese traditional medicine composition for treating nephrotic syndrome |
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| CNA2007101183160A Pending CN101095901A (en) | 2007-07-05 | 2007-07-05 | Chinese traditional medicine composition for treating nephrotic syndrome |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102698139A (en) * | 2012-06-26 | 2012-10-03 | 陈慧婷 | Dangshen Chinese medicinal preparation for treating hypersomnia and preparation method thereof |
| CN103404659A (en) * | 2013-08-06 | 2013-11-27 | 北京绿源求证科技发展有限责任公司 | Kidney nourishing eatable health tea electuary |
-
2007
- 2007-07-05 CN CNA2007101183160A patent/CN101095901A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102698139A (en) * | 2012-06-26 | 2012-10-03 | 陈慧婷 | Dangshen Chinese medicinal preparation for treating hypersomnia and preparation method thereof |
| CN102698139B (en) * | 2012-06-26 | 2013-08-28 | 陈慧婷 | Dangshen Chinese medicinal preparation for treating hypersomnia and preparation method thereof |
| CN103404659A (en) * | 2013-08-06 | 2013-11-27 | 北京绿源求证科技发展有限责任公司 | Kidney nourishing eatable health tea electuary |
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Open date: 20080102 |