CN101112492A - Chinese traditional medicine preparations for treating diabetic hypertension - Google Patents

Chinese traditional medicine preparations for treating diabetic hypertension Download PDF

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Publication number
CN101112492A
CN101112492A CNA2007101209480A CN200710120948A CN101112492A CN 101112492 A CN101112492 A CN 101112492A CN A2007101209480 A CNA2007101209480 A CN A2007101209480A CN 200710120948 A CN200710120948 A CN 200710120948A CN 101112492 A CN101112492 A CN 101112492A
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China
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chinese medicine
portions
traditional chinese
diabetic hypertension
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CNA2007101209480A
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Chinese (zh)
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王信锁
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Beijing Yixintang Medicine Institute
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Beijing Yixintang Medicine Institute
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Priority to CNA2007101209480A priority Critical patent/CN101112492A/en
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Abstract

The present invention relates to a traditional Chinese medicine preparation for treating diabetic hypertension, which takes more than 10 Chinese herbal medicines of barbary wolfberry fruit, Cherokee rose, nacre, prepared turtle shell etc. as the raw materials. The present invention has the effects of suppressing hyperactive liver, subsiding yang, tonifying kidney and lowering blood pressure. Based on the differential treatment of the traditional Chinese medicine, the invention is developed by combining the latest scientific research results with the traditional Chinese medicine. The present invention aims at providing the traditional Chinese medicine preparation to treat diabetic hypertension. The present invention is characterized by accurate efficacy, safety, convenience, no toxicity or side effects and low price.

Description

A kind of Chinese medicine preparation for the treatment of diabetic hypertension
Technical field
The present invention relates to a kind of Chinese medicine preparation for the treatment of diabetic hypertension, is that a kind of diabetic hypertension for the treatment of is the Chinese medicine preparation of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Hypertension is a kind of syndrome based on the systemic arterial pressure rising, is one of diabetes common complication.Itself be a kind of disease be again the pathologic basis of the risk factor of other diseases, especially diabetic coronary artery disease, diabetic cerebrovascular disease, also be to promote diabetic retinopathy and diabetic nephropathy that the principal element of development takes place.Countries in the world have generally acknowledged that diabetic hypertension is apparently higher than the non-diabetic person.Diabetic hypertension is this with the deficiency of YIN based on diabetes, is in YIN failing to keep YANG well, take place on the basis of excessive rising of liver-YANG, and be primary symptom with the dizziness and blurred vision, be equivalent to " dizziness ", " headache " category in the Chinese medicine." element ask the most pure virginity will discuss greatly " cloud: " all wind trembling and dizziness all belong to liver, " points out that dizzy is because due to the excessive rising of liver-YANG.Point out in " Ling Shu Miraculous Pivot or Divine Axis sea opinion ": " deficiency of marrow-reservoir, vertigo and tinnitus then, soreness of the shank, dizzy emitting, " to illustrate dizzy be because of deficiency of the kidney yin, deficiency of marrow-reservoir, can not on fill due to the brain.The diabetic hypertension person, it is primary symptom that clinical manifestation is held concurrently dizzy to quench one's thirst.The traditional Chinese medical science divides clinically that the hepatic and renal YIN deficiency, excessive rising of liver-YANG, deficiency of YIN of both the heart and liver, heart-fire are high partially, the hepatic and renal YIN deficiency, high partially, the deficiency of both YIN and YANG of fire, the expectorant stasis of blood are handed over disease type Coryza Treated by Syndrome Differentiation such as resistance mutually, obtain very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine preparation for the treatment of diabetic hypertension.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by the following weight proportion raw material:
0.1~2 part of 1.0~4 parts of Cherokee rose of 1.5~6 parts of Fructus Lycii of Radix Rehmanniae Preparata
0.1~2 part of 1.0~4 parts of Radix Morindae Officinalis of 1.5~6 parts of Flos Chrysanthemis of Concha Margaritifera
0.1~2 part of 1.0~4 parts of Cortex Eucommiae (parched) of 1.5~6 portions of Rhizoma Dioscoreaes of Concha Ostreae
0.1~2 part of 1.0~4 portions of Semen Plantaginis of 1.5~6 portions of Radix Scrophulariaes of Carapax Trionycis (processed).
The weight proportion of each raw material of optimization formula of the present invention is:
0.5~1.5 part of 1.5~2.5 parts of Cherokee rose of 2.5~3.5 parts of Fructus Lycii of Radix Rehmanniae Preparata
0.5~1.5 part of 1.5~2.5 parts of Radix Morindae Officinalis of 2.5~3.5 parts of Flos Chrysanthemis of Concha Margaritifera
0.5~1.5 part of 1.5~2.5 parts of Cortex Eucommiae (parched) of 2.5~3.5 portions of Rhizoma Dioscoreaes of Concha Ostreae
0.5~1.5 part of 1.5~2.5 portions of Semen Plantaginis of 2.5~3.5 portions of Radix Scrophulariaes of Carapax Trionycis (processed).
The weight proportion of each raw material of optimum formula of the present invention is:
1 part of 2 parts of Cherokee rose of 3 parts of Fructus Lycii of Radix Rehmanniae Preparata
1 part of 2 parts of Radix Morindae Officinalis of 3 parts of Flos Chrysanthemis of Concha Margaritifera
1 part of 2 parts of Cortex Eucommiae (parched) of 3 portions of Rhizoma Dioscoreaes of Concha Ostreae
1 part of 2 portions of Semen Plantaginis of 3 portions of Radix Scrophulariaes of Carapax Trionycis (processed).
Drug action mechanism among the present invention is as follows:
The Radix Rehmanniae Preparata sweet in the mouth, slightly warm in nature.Have nourishing YIN and supplementing blood, beneficial essence is filled out the effect of marrow.Can treat soreness of the waist and knees, osteopyrexia and fever, the night sweat seminal emission, interior-heat is quenched one's thirst, severe palpitation, menoxenia, metrostaxis, dizzy, tinnitus, early whitening of beard and hair, anemia etc.(the 197th page of chief editor such as the firm Xiao Ying of party " Chinese medicine and health food development and exploitation " People's Health Publisher).
The Concha Margaritifera property of medicine is sweet, salty, and is cold.Return liver, heart channel.Has suppressing the hyperactive liver and subsiding YANG, the arresting convulsion of calming the nerves, the effect of liver heat removing and eyesight improving.It is dizzy to treat headache, palpitation and insomnia, demented infantile convulsion, liver-heat conjunctival congestion, pterygium etc.(the 2103rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Concha Ostreae property of medicine is salty, is slightly cold.Return liver, kidney channel.Have suppressing the hyperactive liver and subsiding YANG, tranquillization with heavy prescription, hard masses softening and resolving is restrained astringent or styptic treatment for spontaneous sweating effect.Can treat vertigo and tinnitus, palpitation with fear insomnia, scrofula goiter , mass in the abdomen mass in the abdomen, spontaneous sweating, seminal emission, metrorrhagia, leukorrhagia etc.(the 1574th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Carapax Trionycis (processed) property of medicine is salty, is slightly cold.Return liver, kidney channel.Has nourishing YIN and clearing away heat, suppressing hyper-yang to eliminate wind, the effect of hard masses softening and resolving.Can treat fever due to yin deficiency, consumptive fever hectic fever due to YIN-deficiency, consumption of YIN caused by febrile disease, stirring-up of pathogenic wind in the interior resulting from deficiency, pediatric epilepsy scared, chronic malaria, malaria with splenomegaly , mass in the abdomen, amenorrhea etc.(the 3369th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Fructus Lycii property of medicine is sweet, flat.Return liver, kidney, lung meridian.Has nourishing the liver, nourishing kidney, the effect of lung moistening.Can treat caused by liver and kidney deficiency, have a dizzy spell, visual unclear, soreness of the waist and knees, impotence and seminal emission, cough due to consumptive disease, the taking fluids profusely etc. of quenching one's thirst.(the 2248th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Flos Chrysanthemi property of medicine is sweet, bitter, is slightly cold.Return lung, Liver Channel.Have wind and heat dispersing, suppressing the hyperactive liver makes eye bright, the effect of removing toxic substances and promoting subsidence of swelling.Can treat affection due to external wind and heat or pathogenic wind-warm from the beginning of, fever and headache, dizzy, conjunctival congestion and swelling pain, furuncle swelling toxin etc.(the 2900th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Rhizoma Dioscoreae property of medicine is sweet, flat.Return spleen, lung, kidney channel.Have spleen reinforcing, support lung, reinforce the kidney, the effect that benefit is smart.Can treat diarrhea due to hypofunction of the spleen, the lack of appetite edema, cough and asthma due to lung deficiency is quenched one's thirst, seminal emission, leukorrhagia, the frequent micturition of suffering from a deficiency of the kidney.Carbuncle is controlled in external, scrofula etc.(the 218th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Scrophulariae property of medicine is sweet, bitter, salty, is slightly cold.Return lung, stomach, kidney channel.Has removing heat from blood, nourishing YIN to lower pathogenic fire, antidotal effect.Can treat the warm febrile disease blood of joining the army, fever of the body, excessive thirst, crimson tongue is sent out speckle, the hectic fever due to YIN-deficiency chronic cough, fidgets due to deficiency is insomnia, and constipation is hindered in Tianjin, and order is puckery dim-sighted, laryngopharynx swelling and pain, tuberculous lymphadenitis, skin sore etc.(the 1062nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Fructus Rosae Laevigatae property of medicine acid, puckery, flat.Return spleen, kidney, urinary bladder channel.Has controlling nocturnal emission with astringent drugs, reducing urination, astringing intestine to stop diarrhea, the effect of leukorrhagia stopping.Can treat seminal emission, spermatorrhea, the enuresis, frequent micturition, chronic diarrhea, chronic dysentery, nebulousurine, leukorrhagia, metrorrhagia etc.(the 1976th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Morindae Officinalis property of medicine suffering, sweet, tepor.Return liver, kidney channel.Has reinforcing the kidney and supporting YANG, bone and muscle strengthening, the effect of expelling wind and removing dampness.Can treat impotence due to deficiency of the kidney, the seminal emission premature ejaculation, few abdomen cold type of pain, incontinence of urine, cold womb is infertile, anemofrigid-damp arthralgia, soreness of the waist and knees, rheumatism beriberi etc.(the 709th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Sweet, the little suffering of the Cortex Eucommiae (parched) property of medicine, temperature.Return liver, kidney channel.Has invigorating the liver and kidney, bone and muscle strengthening, antiabortive effect.Can treat soreness of waist and knee joint, sexual impotence, frequent micturition, dribbling urination, rheumatic arthralgia, frequent fetal movement, habitual abortion etc.(the 1514th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Semen Plantaginis property of medicine is sweet, light, is slightly cold.Return lung, liver, kidney, urinary bladder channel.Have heat clearing away, diuresis makes eye bright, the expectorant effect.Can treat urinary obstruction, stranguria with turbid discharge, leukorrhagia, edema, the heat-damp in summer dysentery, conjunctival congestion is hidden from view, and the expectorant heat syndrome cough is breathed heavily etc.(the 539th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Radix Rehmanniae Preparata, Concha Margaritifera, Concha Ostreae and Carapax Trionycis (processed); With Fructus Lycii, Flos Chrysanthemi, Rhizoma Dioscoreae and Radix Scrophulariae is ministerial drug; With Cherokee rose, Radix Morindae Officinalis, Cortex Eucommiae (parched) and Semen Plantaginis is adjuvant.All medicines are harmonious, and are total to the tool suppressing the hyperactive liver and subsiding YANG, the effect of kidney tonifying blood pressure lowering.The treatment diabetic hypertension has determined curative effect, has no side effect taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment diabetic hypertension of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat diabetic hypertension, and the prevention of diabetic hypertension is also had good effect, and the treatment diabetic hypertension has determined curative effect, has no side effect taking convenience, cheap characteristics.
For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment diabetic hypertension; Treatment diabetic hypertension patient 16 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.One month is a course of treatment, take continuously three the course of treatment observe the curative effect.6 examples of fully recovering account for 37.5%, and 8 examples that take a turn for the better account for 50%, and invalid 2 examples account for 12.5%, and total effective rate reaches 87.5%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
The embodiment decoction takes by weighing raw material by following weight:
1 part of 2 parts of Cherokee rose of 3 parts of Fructus Lycii of Radix Rehmanniae Preparata
1 part of 2 parts of Radix Morindae Officinalis of 3 parts of Flos Chrysanthemis of Concha Margaritifera
1 part of 2 parts of Cortex Eucommiae (parched) of 3 portions of Rhizoma Dioscoreaes of Concha Ostreae
1 part of 2 portions of Semen Plantaginis of 3 portions of Radix Scrophulariaes of Carapax Trionycis (processed).
Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5~2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1~1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment diabetic hypertension that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.One month is a course of treatment.

Claims (3)

1. Chinese medicine preparation for the treatment of diabetic hypertension is characterized in that it is made by the following weight proportion raw material:
0.1~2 part of 1.0~4 parts of Cherokee rose of 1.5~6 parts of Fructus Lycii of Radix Rehmanniae Preparata
0.1~2 part of 1.0~4 parts of Radix Morindae Officinalis of 1.5~6 parts of Flos Chrysanthemis of Concha Margaritifera
0.1~2 part of 1.0~4 parts of Cortex Eucommiae (parched) of 1.5~6 portions of Rhizoma Dioscoreaes of Concha Ostreae
0.1~2 part of 1.0~4 portions of Semen Plantaginis of 1.5~6 portions of Radix Scrophulariaes of Carapax Trionycis (processed).
2. a kind of Chinese medicine preparation for the treatment of diabetic hypertension according to claim 1, wherein the weight proportion of each raw material is:
0.5~1.5 part of 1.5~2.5 parts of Cherokee rose of 2.5~3.5 parts of Fructus Lycii of Radix Rehmanniae Preparata
0.5~1.5 part of 1.5~2.5 parts of Radix Morindae Officinalis of 2.5~3.5 parts of Flos Chrysanthemis of Concha Margaritifera
0.5~1.5 part of 1.5~2.5 parts of Cortex Eucommiae (parched) of 2.5~3.5 portions of Rhizoma Dioscoreaes of Concha Ostreae
0.5~1.5 part of 1.5~2.5 portions of Semen Plantaginis of 2.5~3.5 portions of Radix Scrophulariaes of Carapax Trionycis (processed).
3. a kind of Chinese medicine preparation for the treatment of diabetic hypertension according to claim 1, wherein the weight proportion of each raw material is:
1 part of 2 parts of Cherokee rose of 3 parts of Fructus Lycii of Radix Rehmanniae Preparata
1 part of 2 parts of Radix Morindae Officinalis of 3 parts of Flos Chrysanthemis of Concha Margaritifera
1 part of 2 parts of Cortex Eucommiae (parched) of 3 portions of Rhizoma Dioscoreaes of Concha Ostreae
1 part of 2 portions of Semen Plantaginis of 3 portions of Radix Scrophulariaes of Carapax Trionycis (processed).
CNA2007101209480A 2007-08-29 2007-08-29 Chinese traditional medicine preparations for treating diabetic hypertension Pending CN101112492A (en)

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Application Number Priority Date Filing Date Title
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2953103A1 (en) * 2009-11-30 2011-06-03 Camprasse Steeve Harold Metabolism modifying nutritional supplement, useful in the formulation of e.g. gel capsules, tablets, lozenges, gels, and granules, comprises powder of Lycium barbarum and Lycium chinense berry coating microgranules of marine aragonite

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2953103A1 (en) * 2009-11-30 2011-06-03 Camprasse Steeve Harold Metabolism modifying nutritional supplement, useful in the formulation of e.g. gel capsules, tablets, lozenges, gels, and granules, comprises powder of Lycium barbarum and Lycium chinense berry coating microgranules of marine aragonite

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Open date: 20080130