CN101095873A - Chinese patent medicine for treating diabetes peripheral neuritis - Google Patents

Abstract

The invention relates to a Chinese medicament for treating diabetic peripheral neuritis, which is prepared from more than ten kinds of Chinese medicinal herbs including anemarrhena rhizome, root of red rooted saliva, ophiopogon root and corydalis tuber. The medicament has the advantages of assured curative effect, safe and convenient application, no toxic and side effects, and low price.

Description

A kind of Chinese patent medicine of treatment diabetes peripheral neuritis

Technical field

The present invention relates to treat a kind of Chinese patent medicine of diabetes peripheral neuritis, is that a kind of diabetes peripheral neuritis for the treatment of is the Chinese medicine preparation of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.

Background technology

Diabetic peripheral neuropathy is more common in above middle age, and the dissatisfied or course of disease of diabetes control is than the elder.Small number of patients is first symptom with neuropathy.What the most common and symptom early occurred is the lower limb pathological changes.The diabetic neuropathy complicated clinical, its sorting technique is multiple, does not reach an agreement as yet.For ease of clinical observation, so classify in conjunction with lesion nature by diseased region.Peripheral neuropathy claims the peripheral nerve sexually transmitted disease (STD) to become again.Be divided into multiple neuropathy of symmetry and the multiple mononeuropathy change of asymmetry by its clinical manifestation.Wherein the multiple neuropathy of symmetry also comprises: far-end symmetry sensory nerve pathological changes, symmetry nervus motorius pathological changes; Asymmetry polyneuropathy and mononeuropathy are mainly due to the nerve trunk vasa vasorum blood supply insufficiency.According to the clinical manifestation of multiple neuropathy, " arthromyodynia " of the suitable traditional Chinese medical science, " pain card ", " myopathy " scope.Primary disease system is because of the diabetes obstinate disease, and prolonged illness must be empty, and consumption is hindered healthy energy, causes insufficiency of vital energy and blood, incoordination between nutrient QI and defensive QI, and collaterals being void and defenceless, QI-blood circulation is not smooth." Lei Zheng Zhi Cai ": " all coagulation of QI-blood form numbness for a long time." just recognize " greatly through inanition " as far back as ancient times, and recognize that the generation of myopathy and diseases of five ZANG-organs in a disguised form close.The traditional Chinese medical science is divided disease type Coryza Treated by Syndrome Differentiation such as deficiency of vital energy arthralgia due to stagnation of blood, Liver and kidney two void, insufficiency of the spleen stagnation of phlegm, stasis of blood resistance venation clinically, obtains very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.

Summary of the invention

The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine preparation for the treatment of diabetes peripheral neuritis.Have determined curative effect, safe ready, have no side effect, cheap characteristics.

The present invention is made by the following weight proportion raw material:

1.5～6 parts of 1.5～6 parts of Rhizoma Anemarrhenaes of 1.5～6 parts of Radix Salviae Miltiorrhizaes of Semen Coicis

1.0～4 parts in 1.0～4 parts of Poria of 1.0～4 portions of Radix Cyathulaes of Radix Ophiopogonis

1.0～4 parts of 1.0～4 portions of Rhizoma Alismatis of 1.0～4 portions of Radix Paeoniae Albas of Rhizoma Corydalis

0.1～2 part of 0.1～2 portion of Cortex Phellodendri of 0.1～2 part of Rhizoma Atractylodis of Radix Trichosanthis.

The weight proportion of each raw material of optimization formula of the present invention is:

2.5～3.5 parts of 2.5～3.5 parts of Rhizoma Anemarrhenaes of 2.5～3.5 parts of Radix Salviae Miltiorrhizaes of Semen Coicis

1.5～2.5 parts in 1.5～2.5 parts of Poria of 1.5～2.5 portions of Radix Cyathulaes of Radix Ophiopogonis

1.5～2.5 parts of 1.5～2.5 portions of Rhizoma Alismatis of 1.5～2.5 portions of Radix Paeoniae Albas of Rhizoma Corydalis

0.5～1.5 part of 0.5～1.5 portion of Cortex Phellodendri of 0.5～1.5 part of Rhizoma Atractylodis of Radix Trichosanthis.

The weight proportion of each raw material of optimum formula of the present invention is:

3 parts of 3 parts of Rhizoma Anemarrhenaes of 3 parts of Radix Salviae Miltiorrhizaes of Semen Coicis

2 parts in 2 parts of Poria of 2 portions of Radix Cyathulaes of Radix Ophiopogonis

2 parts of 2 portions of Rhizoma Alismatis of 2 portions of Radix Paeoniae Albas of Rhizoma Corydalis

1 part of 1 portion of Cortex Phellodendri of 1 part of Rhizoma Atractylodis of Radix Trichosanthis.

Drug action mechanism among the present invention is as follows:

The Semen Coicis property of medicine is sweet, light, is slightly cold.Return spleen, stomach, lung meridian.Has the dampness removing spleen invigorating, arthralgia relieving by relaxing muscles and tendons, the effect of clearing away heat and discharging pus.Can treat edema, beriberi, dribbling urination, damp-warm diseases is had loose bowels, leukorrhagia, rheumatic arthralgia, the contracture of muscle arteries and veins, lung abscess, acute appendicitis, verruca plana etc.(the 3725th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Radix Salviae Miltiorrhizae property of medicine hardship is slightly cold.GUIXIN, pericardium, Liver Channel.Have blood circulation promoting and blood stasis dispelling, menstruction regulating and pain relieving, relieving restlessness is calmed the nerves, the effect of removing heat from blood eliminating carbuncle.Can treat menoxenia, dysmenorrhea, amenorrhea, the stasis of blood stagnated and suffered from abdominal pain puerperal, trusted subordinate's pain, lumps in the chest and abdomen, pyretic arthralgia swells and ache, traumatic injury, heat is gone into nutrient blood, dysphoria, vexed insomnia, carbuncle pyogenic infections from tumour or sore etc.(the 647th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Rhizoma Anemarrhenae property of medicine hardship, cold.Return lung, stomach, kidney channel.Has clearing away heat-fire, nourishing yin and moistening dryness.Can treat epidemic febrile disease hyperpyrexia excessive thirst, the cough due to lung-heat, osteopyrexia and fever, seminal emission, night sweat, restlessness of asrhenia type and insomnia is quenched one's thirst etc.(the 1924th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Sweet, the little hardship of the Radix Ophiopogonis property of medicine is slightly cold.Return lung, stomach, heart channel.Has nourishing YIN and moistening the lung, nourishing the stomach to promote the production of body fluid, the effect of the relieving restlessness that clears away heart-fire.Can treat dryness of the lung dry cough, lung abscess, deficiency of YIN chronic cough, Tianjin wound is thirsty, quenches one's thirst, and vexed insomnia is had sore throat, the dryness of the intestine constipation, heat in blood is told nosebleed etc.(the 1430th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Sweet, the little hardship of the Radix Cyathulae property of medicine, flat.Return liver, kidney channel.Has blood circulation promoting and blood stasis dispelling, the effect of expelling wind and removing dampness.Can treat the blood stasis amenorrhea, difficult labour, retention of placenta, postnatal blood stasis stomachache, pyretic stranguria, stranguria caused by urinary stone, dysmenorrhea, rheumatism lumbocrural pain, traumatic injury etc.(the 301st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Poria property of medicine is sweet, light, and is flat.GUIXIN, spleen, lung, kidney channel.Has promoting diuresis to eliminate damp pathogen, invigorating the spleen and regulating the stomach, the effect of mind tranquilizing and the heart calming.Can treat dysuria, the edema distension, is had loose bowels at phlegm retention cough with dyspnea, vomiting, insufficiency of the spleen lack of appetite, palpitation and restlessness, insomnia forgetfulness, seminal emission nebulousurine etc.(the 2154th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Rhizoma Corydalis property of medicine suffering, hardship, temperature.GUIXIN, liver, spleen channel.Has promoting blood circulation to remove blood stasis, the effect of promoting the circulation of QI to relieve pain.Can treat obstruction of qi in the chest and cardialgia, epigastric pain, lumbago, colicky, dysmenorrhea, amenorrhea ， mass in the abdomen, the stasis of blood stagnated and suffered from abdominal pain traumatic injury etc. puerperal.(the 1261st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Radix Paeoniae Alba property of medicine hardship, acid are slightly cold.Return liver, spleen channel.Have and nourish blood and seek relieving spasm to stop pain, the effect of yin fluid astringing suppressing the hyperactive liver.Can treat the blood deficiency cold and heat, epigastric pain, hypochondriac pain, limb spasm pain, dysmenorrhea, menoxenia, metrorrhagia, spontaneous perspiration, night sweat, dysentery is had loose bowels, and it is dizzy to have a headache etc.(the 948th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Rhizoma Alismatis property of medicine is sweet, light, and is cold.Return kidney, urinary bladder channel.Have promoting diuresis to eliminate damp pathogen, treating stranguria effect expels the heat-evil.Can treat dysuria, the puckery pain of pyretic stranguria, the edema distension is had loose bowels, dizziness due to fluid-retention, seminal emission etc.(the 2067th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Sweet, the little hardship of the Radix Trichosanthis property of medicine is slightly cold.Attach to the lung and stomach meridians.Has clearing away heat and promoting production of body fluid, moistening the lung and resolving phlegm, the effect of detumescence and apocenosis.It is thirsty to treat calentura, the polydipsia of quenching one's thirst, lung-heat type cough, sore swollen toxin etc.(the 443rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Rhizoma Atractylodis property of medicine suffering, hardship, temperature.Return spleen, stomach, Liver Channel.Have drying damp and strengthening spleen, wind-damp dispelling, the effect that makes eye bright.Can treat the spleen and stomach being stranded by dampness, the asthenia drowsiness, feeling of stuffiness in chest abdominal distention, inappetence, vomiting is had loose bowels, phlegm retention, damp-edema, the exterior syndrome folder is wet, a heavy sensation of the body pain, arthromyodynia domination of damp pathogen, podomere are ached and are being weighed, and flaccidity is sprained, nyctalopia etc.(the 1485th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Cortex Phellodendri property of medicine hardship, cold.Return kidney, bladder, large intestine channel.Has heat clearing and damp drying, the effect of eliminating fire and detoxication.Can treat hygropyretic dysentery, have loose bowels, jaundice, nocturnal emission, stranguria with turbid discharge, leukorrhagia, hectic fever due to YIN-deficiency consumptive fever ， Wei Bi, and aphtha of the mouth and tongue, conjunctival congestion and swelling pain, skin sore, skin eczema etc.(the 2823rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Semen Coicis, Radix Salviae Miltiorrhizae and the Rhizoma Anemarrhenae; With Radix Ophiopogonis, Radix Cyathulae, Poria, Rhizoma Corydalis, the Radix Paeoniae Alba and Rhizoma Alismatis is ministerial drug; With Radix Trichosanthis, Rhizoma Atractylodis and Cortex Phellodendri is adjuvant.All medicines are harmonious, and are total to the tool clearing away heat-damp and promoting diuresis, the effect of promoting blood circulation and stopping pain.The treatment diabetes peripheral neuritis has determined curative effect, has no side effect taking convenience, cheap characteristics.Clinical drug of the present invention uses the result to show that following advantage is arranged:

1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of Pharmacopoeia of People's Republic of China, utilizes the comprehensive function treatment diabetes peripheral neuritis of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.

2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.

3, the present invention not only can effectively treat diabetes peripheral neuritis, and the prevention of diabetes peripheral neuritis is also had good effect, and the treatment diabetes peripheral neuritis has determined curative effect, has no side effect taking convenience, cheap characteristics.

For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment diabetes peripheral neuritis; Treatment diabetes peripheral neuritis patient 28 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.One month is a course of treatment, take continuously three the course of treatment observe the curative effect.18 examples of fully recovering account for 64.28%, and 6 examples that take a turn for the better account for 21.43%, and invalid 4 examples account for 14.29%, and total effective rate reaches 85.71%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.

The specific embodiment

The embodiment decoction takes by weighing raw material by following weight:

3 parts of 3 parts of Rhizoma Anemarrhenaes of 3 parts of Radix Salviae Miltiorrhizaes of Semen Coicis

2 parts in 2 parts of Poria of 2 portions of Radix Cyathulaes of Radix Ophiopogonis

2 parts of 2 portions of Rhizoma Alismatis of 2 portions of Radix Paeoniae Albas of Rhizoma Corydalis

1 part of 1 portion of Cortex Phellodendri of 1 part of Rhizoma Atractylodis of Radix Trichosanthis.

Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5～2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1～1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment diabetes peripheral neuritis that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.One month is a course of treatment.

Claims (3)

1, a kind of Chinese patent medicine of treatment diabetes peripheral neuritis is characterized in that it is made by the following weight proportion raw material:

1.5～6 parts of 1.5～6 parts of Rhizoma Anemarrhenaes of 1.5～6 parts of Radix Salviae Miltiorrhizaes of Semen Coicis

1.0～4 parts in 1.0～4 parts of Poria of 1.0～4 portions of Radix Cyathulaes of Radix Ophiopogonis

1.0～4 parts of 1.0～4 portions of Rhizoma Alismatis of 1.0～4 portions of Radix Paeoniae Albas of Rhizoma Corydalis

0.1～2 part of 0.1～2 portion of Cortex Phellodendri of 0.1～2 part of Rhizoma Atractylodis of Radix Trichosanthis.

2, a kind of Chinese patent medicine of treatment diabetes peripheral neuritis according to claim 1, wherein the weight proportion of each raw material is:

2.5～3.5 parts of 2.5～3.5 parts of Rhizoma Anemarrhenaes of 2.5～3.5 parts of Radix Salviae Miltiorrhizaes of Semen Coicis

1.5～2.5 parts in 1.5～2.5 parts of Poria of 1.5～2.5 portions of Radix Cyathulaes of Radix Ophiopogonis

1.5～2.5 parts of 1.5～2.5 portions of Rhizoma Alismatis of 1.5～2.5 portions of Radix Paeoniae Albas of Rhizoma Corydalis

0.5～1.5 part of 0.5～1.5 portion of Cortex Phellodendri of 0.5～1.5 part of Rhizoma Atractylodis of Radix Trichosanthis.

3, a kind of Chinese patent medicine of treatment diabetes peripheral neuritis according to claim 1, wherein the weight proportion of each raw material is:

3 parts of 3 parts of Rhizoma Anemarrhenaes of 3 parts of Radix Salviae Miltiorrhizaes of Semen Coicis

2 parts in 2 parts of Poria of 2 portions of Radix Cyathulaes of Radix Ophiopogonis

2 parts of 2 portions of Rhizoma Alismatis of 2 portions of Radix Paeoniae Albas of Rhizoma Corydalis

1 part of 1 portion of Cortex Phellodendri of 1 part of Rhizoma Atractylodis of Radix Trichosanthis.