CN101085054B - Liver-nourishing powder containing bupleurum, rhubarb and other medicine for aquatic animals - Google Patents
Liver-nourishing powder containing bupleurum, rhubarb and other medicine for aquatic animals Download PDFInfo
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- CN101085054B CN101085054B CN200710057757A CN200710057757A CN101085054B CN 101085054 B CN101085054 B CN 101085054B CN 200710057757 A CN200710057757 A CN 200710057757A CN 200710057757 A CN200710057757 A CN 200710057757A CN 101085054 B CN101085054 B CN 101085054B
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Abstract
The invention relates to a medicament for the effective prevention and treatment of aquatic animal liver diseases which comprises the following raw materials (by weight portion): bupleurum root 200-400 parts, dyers woad leaf 300-400 parts, rheum officinale 100-200 parts, motherwort 20-70 parts. The preparing process consists of carrying out ultramicro disintegration to the herbs, then passing through 100-300 mesh sieves.
Description
Technical field
The invention belongs to pure Chinese medicine hepatic, relate in particular to a kind of liver-nourishing powder containing bupleurum, rhubarb and other medicine that is used for aquatic animal.
Background technology
In numerous aquatic animal diseases, often with the different liver tissue lesions of degree.Cause the liver tissue lesions except that cultivated animals suffers pathogenic microorganism (antibacterial, virus etc.) invasion and attack, some extrinsic factors also are the major reasons that causes the aquatic animal hepatopathy.1), trophic factor mainly include:: trophic factors is unbalance in the feedstuff, and particularly fat, glucide too much and lack vitamin can cause tangible liver pathological changes; 2), poisonous substance factor: the mould toxin in the pesticide in the water body, heavy metal, toxic gas, algae toxin, the feedstuff etc. all can cause hepatic tissue to change, and influences the normal function of liver; 3), medicine factor: prevent and treat in the process at aquatic animal disease; usually can adopt the method for chemical drugss such as disinfectant sterilization water body and mixed feeding antibiotics; and a large amount of and life-time service of this quasi drugs; it also often causes comparatively serious hepatic injury to target animals in pathogenic microbe killing.As tetracycline, chloromycetin, erythromycin, furans medicine etc.To a certain extent, hepatopathy has become influences the big obstacle that culture fishery develops in a healthy way, hepatopathy mainly show as fatty liver, the enlargement of liver pancreas, liver cirrhosis, hemorrhage, the hepatic necrosis of liver pancreas, the cycle of this type of disease treatment is longer comparatively speaking, cure rate is lower.Adopt Chinese medicine preparation treatment aquatic animal hepatopathy, because the granularity that the Chinese herbal medicine product is pulverized is thicker relatively, general 50-60 order, Chinese medicine powder crude fiber content height, effective ingredient is difficult to the deficiency of stripping, can't effectively prevent and treat aquatic animal liver class disease.
Summary of the invention
The object of the invention is to overcome the deficiencies in the prior art, a kind of liver-nourishing powder containing bupleurum, rhubarb and other medicine that is used for aquatic animal is provided, Chinese crude drug is carried out micronizing, make it pass through the 100-300 mesh sieve, destroy plant cell wall to greatest extent, solved Chinese medicine powder crude fiber content height, effective ingredient is difficult to the deficiency of stripping, effectively prevents and treat aquatic animal liver class disease.
The present invention is achieved through the following technical solutions: a kind of liver-nourishing powder containing bupleurum, rhubarb and other medicine that is used for aquatic animal is characterized in that: form by following medicine, count by weight,
20～70 parts of 100～200 parts of Herba Leonuris of 300～400 parts of Radix Et Rhizoma Rhei of 200～400 portions of Folium Isatidiss of Radix Bupleuri are pulverized and are mixed.
The preparation method of liver-nourishing powder containing bupleurum, rhubarb and other medicine is as follows:
(1), get respectively the distinguish the flavor of effective site of medical material of Radix Bupleuri, Folium Isatidis, Radix Et Rhizoma Rhei, Herba Leonuri, through micronizing after the assay was approved, the 100-300 order sieves;
(2), in the umber ratio with each respectively weighing of flavor medical material, in mixer,, carry out packing according to packing specification then, then the packing warehouse-in with its uniform mixing.
The characteristic of medicine
(1), Radix Bupleuri: perennial herb, main root is cylindrical, matter is hard, root is directly given birth to.The Radix Bupleuri root contains volatile oil, bupleurumol, oleic acid, linolenic acid, Palmic acid, hard ester acid, carnaubic acid, glucose and Saponin etc., saikoside is arranged, saikoside unit, longispinogenin in the Saponin.Property of medicine hardship is slightly cold.Have antiviral, kill protozoon effect, anti-hepar damnification effect.
(2), Folium Isatidis: the roadside Folium Isatidis contains flavonoid.The polygonum tinctorium ait. herb contains indigo glycoside, flavochrome and tannin.Contain the anthraquinone class in the root.The Isatis indigotica Fort. leaf contains tryptophan, isatan B, glucose Caulis et Folium Brassicae campestris element, new glucose Caulis et Folium Brassicae campestris element, glucose Caulis et Folium Brassicae campestris element-1-sulfonate.Contain indigo again.The grass Folium Isatidis contains the indigo glycoside.Folium acanthaceous indigo contains the indigo glycoside.The hydrolysis of indigo glycoside generates indoxyl.Indoxyl promptly generates indigo through oxidation.Property of medicine hardship, cold.Has antibiotic, antivirus action.
(3), Radix Et Rhizoma Rhei: anthraquinone analog compound, comprise in conjunction with or chrysophanol, emodin, aloe-emodin, chrysophanic acid and the physcione of free state.Radix Et Rhizoma Rhei also contains rheotannic acid and related substances thereof, as gallic acid, cachou extract and tetrarin.These tannic acids and related substances thereof have anti-diarrhea effect, and be just opposite with the discharge function of the glycoside of anthraquinone derivative.In addition, Radix Et Rhizoma Rhei also contains fatty acid, as caproic acid, Palmic acid, stearic acid, oleic acid, linoleic acid plus linolenic acid.
(4), Herba Leonuri: the Herba Leonuri herb contains leonurine (leonurine) about 0.05% and (spends the initial stage to contain trace, spend increase gradually mid-term), stachydrine (stachydrine), rutin (rutin), Fumaric acid (fumaric acid fumaric acid), leonurine first and leonurine second.The Herba Leonuri Sibirici herb contains alkaloid 0.05%.The content of leonurine is with changing the period of blooming in the herb, the initial stage content of spending is very little, it is 0.01-0.03% that 7-8 spends mid-term content the middle of the month, reach as high as 0.04%, and contain stachydrine, leonuridine alkali (leonuridine), 4-guanidine radicals butanols-1 (4-guanidino-l-butanol), 4-guanidine radicals butanoic acid (4-guanidino-butyric acid), arginine (arginine), micro-rutin, stachyose (stachyose), plant sterol, resin, fatty oil, lauric acid (lauric acid), linoleic acid (linoleic acid), β-linoleic acid (β-linoleic acid) and oleic acid (oleic acid).Bitter in the mouth, suffering, cold nature.Promoting blood flow to regulate menstruation is arranged, promoting tissue regeneration by removing blood stasis, the function of inducing diuresis to remove edema.The component medicine: each drug component all derives from the commercially available prepared slices of Chinese crude drugs.
Advantage of the present invention is: Chinese crude drug is carried out micronizing, make it pass through the 100-300 mesh sieve, destroy plant cell wall to greatest extent, solved the deficiency that Chinese medicine powder crude fiber content height, effective ingredient are difficult to stripping, effectively prevent and treat aquatic animal liver class disease.
The specific embodiment
The present invention is described in further detail by following examples, but is not limited to present embodiment.
Embodiment 1
The medicine compositing formula
The liver-nourishing powder containing bupleurum, rhubarb and other medicine that is used for aquatic animal, medicine is formed, by weight meter
70 parts of 100 parts of Herba Leonuris of 400 parts of Radix Et Rhizoma Rhei of 200 portions of Folium Isatidiss of Radix Bupleuri.
Embodiment 2
The liver-nourishing powder containing bupleurum, rhubarb and other medicine that is used for aquatic animal, medicine is formed, counts by weight,
20 parts of 200 parts of Herba Leonuris of 300 parts of Radix Et Rhizoma Rhei of 400 portions of Folium Isatidiss of Radix Bupleuri.
Embodiment 3
The liver-nourishing powder containing bupleurum, rhubarb and other medicine that is used for aquatic animal, medicine is formed, by weight,
50 parts of 150 parts of Herba Leonuris of 350 parts of Radix Et Rhizoma Rhei of 300 portions of Folium Isatidiss of Radix Bupleuri.
The preparation method of medicine
1. get respectively the distinguish the flavor of effective site of medical material of Radix Bupleuri, Folium Isatidis, Radix Et Rhizoma Rhei, Herba Leonuri, through micronizing after the assay was approved, the 100-300 order sieves;
2. in the umber ratio each flavor medical material is distinguished weighing, in mixer,, carry out packing according to packing specification then, then the packing warehouse-in its uniform mixing.
Clinical use experiment
10 mu in hard sharp county, Hubei Province crawl, 1 meter of the depth of water, in July, 2006, along with temperature raises, it is very fast that sashimi (raw fish) is grown, various pathogenic bacterium accelerates multiplications, food ration because of fish increases in addition, causes daily ration, feeding quantity to increase, and excretory feces increases, water scarcity, to such an extent as to can not well change water, cause every index ammoniacal nitrogen of water body, hydrogen sulfide, nitrites etc. all raise, to such an extent as to liver and gallbladder syndrome has appearred in fish, fatty liver, the enlargement of liver pancreas, liver cirrhosis, the liver pancreas is hemorrhage, hepatic necrosis, serious appearance hepatic atrophy, the food ration of fish descends, the fish that part is serious has a small amount of phenomena of mortality, analyzing reason may be because feedstuff, water body, fish body etc. causes, the liver-nourishing powder containing bupleurum, rhubarb and other medicine of pressing per kilogram feed-mixing 12.5g used after 3-5 days, and liver has recovered normally, and cure rate has improved more than 10%, use through users, sickness rate has reduced by 5%.
The above only is preferred embodiment of the present invention, is not structure of the present invention is done any pro forma restriction.Every foundation technical spirit of the present invention all still belongs in the scope of technical scheme of the present invention any simple modification, equivalent variations and modification that above embodiment did.
Claims (1)
1. one kind has the liver-nourishing powder containing bupleurum, rhubarb and other medicine of hepatoprotective effect to Fish, it is characterized in that: form by following medicine, and meter by weight,
20～70 parts of 100～200 parts of Herba Leonuris of 300～400 parts of Radix Et Rhizoma Rhei of 200～400 portions of Folium Isatidiss of Radix Bupleuri are pulverized and are mixed.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200710057757A CN101085054B (en) | 2007-06-26 | 2007-06-26 | Liver-nourishing powder containing bupleurum, rhubarb and other medicine for aquatic animals |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN200710057757A CN101085054B (en) | 2007-06-26 | 2007-06-26 | Liver-nourishing powder containing bupleurum, rhubarb and other medicine for aquatic animals |
Publications (2)
| Publication Number | Publication Date |
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| CN101085054A CN101085054A (en) | 2007-12-12 |
| CN101085054B true CN101085054B (en) | 2010-05-26 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN200710057757A Expired - Fee Related CN101085054B (en) | 2007-06-26 | 2007-06-26 | Liver-nourishing powder containing bupleurum, rhubarb and other medicine for aquatic animals |
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Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101933981A (en) * | 2010-08-30 | 2011-01-05 | 天津瑞贝特科技发展有限公司 | Traditional Chinese medicinal composition for treating syndrome of liver and gall of aquatic animals and preparation method thereof |
| CN103127263A (en) * | 2013-02-28 | 2013-06-05 | 张丽香 | Drug for treating oyster perkinsus disease |
| CN104366037A (en) * | 2014-01-17 | 2015-02-25 | 海一（厦门）生物科技有限公司 | Aquatic product liver and gallbladder syndrome control feed additive and preparation method thereof |
| CN104664068A (en) * | 2015-03-18 | 2015-06-03 | 广东迈科特生物科技有限公司 | Special multivitamin immunopolysaccharide microemulsion preparation for waterfowl and preparation method and application thereof |
| CN106177212A (en) * | 2016-08-26 | 2016-12-07 | 桂林聚龙潭生态渔业有限公司 | The method of noxious substance in removal fish body |
| CN106309760A (en) * | 2016-08-26 | 2017-01-11 | 桂林聚龙潭生态渔业有限公司 | Medicine for removing toxic substances in fishes and preparation method of medicine |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1075887A (en) * | 1993-01-18 | 1993-09-08 | 国营常熟制药厂 | The preparation method of KUHUANG ZHUSHEYE |
| CN1546079A (en) * | 2003-12-09 | 2004-11-17 | 李隆伟 | Chinese traditional drug pills capable of protecting liver, resisting hepatic fibrosis and expelling toxins |
| CN1762461A (en) * | 2005-10-07 | 2006-04-26 | 邹巧根 | Rhubarb lyophilized injection and preparation method thereof |
-
2007
- 2007-06-26 CN CN200710057757A patent/CN101085054B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1075887A (en) * | 1993-01-18 | 1993-09-08 | 国营常熟制药厂 | The preparation method of KUHUANG ZHUSHEYE |
| CN1546079A (en) * | 2003-12-09 | 2004-11-17 | 李隆伟 | Chinese traditional drug pills capable of protecting liver, resisting hepatic fibrosis and expelling toxins |
| CN1762461A (en) * | 2005-10-07 | 2006-04-26 | 邹巧根 | Rhubarb lyophilized injection and preparation method thereof |
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| CN101085054A (en) | 2007-12-12 |
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