CN106309760A - Medicine for removing toxic substances in fishes and preparation method of medicine - Google Patents

Medicine for removing toxic substances in fishes and preparation method of medicine Download PDF

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Publication number
CN106309760A
CN106309760A CN201610729161.3A CN201610729161A CN106309760A CN 106309760 A CN106309760 A CN 106309760A CN 201610729161 A CN201610729161 A CN 201610729161A CN 106309760 A CN106309760 A CN 106309760A
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medicine
parts
fishes
radix
preparation
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刘恒坚
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Guilin Longtan Eco Fishery Co Ltd
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Guilin Longtan Eco Fishery Co Ltd
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Priority to CN201610729161.3A priority Critical patent/CN106309760A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233Bupleurum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/19Acanthaceae (Acanthus family)
    • A61K36/195Strobilanthes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282Artemisia, e.g. wormwood or sagebrush
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • A61K36/315Isatis, e.g. Dyer's woad
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/533Leonurus (motherwort)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/63Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/634Forsythia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/708Rheum (rhubarb)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/85Verbenaceae (Verbena family)
    • A61K36/855Clerodendrum, e.g. glorybower
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1611Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1664Compounds of unknown constitution, e.g. material from plants or animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
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  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
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  • Alternative & Traditional Medicine (AREA)
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Abstract

The invention discloses a medicine for removing toxic substances in fishes. The medicine is prepared from, by mass, raw material extracts, 5-20 parts of activated carbon, 10-30 parts of cyclodextrin and an expanded product prepared from expanded materials, wherein the raw material extracts comprise, by mass, 20-70 parts of radix bupleuri, 20-50 parts of prepared rhubarb, 20-70 parts of folium isatidis, 10-30 parts of herba artemisiae capillariae, 15-30 parts of fructus forsythiae and 10-30 parts of herba leonuri. By means of compatibility of the components, the medicine achieves the effects of protecting, caring and strengthening the liver, promotes liver detoxification and enhances toxicant metabolism. The expanded product can float on the water surface to attract the fishes to move for foraging. After the medicine for removing the toxic substances in the fishes is used for 3 d to 5 d, the color of the livers of the fishes becomes bright red from original black or dull black, and it is proved that the effect of removing the toxic substances in the fishes is good and is rapidly achieved. On the other hand, the invention provides a preparation method of the medicine for removing the toxic substances in the fishes.

Description

Medicine of noxious substance and preparation method thereof in removal fish body
Technical field
The present invention relates to breed fish, a kind of remove medicine of noxious substance and preparation method thereof in fish body.
Background technology
Along with water pollutes and the increasing of soil pollution, water body environment is degraded, and causes fish poor growth, disease to increase, dead Die increase, yield reduces, but also cause that its quality declines, meat flavour is the freshest, in meat product containing noxious substance, cause food peace Full problem.Therefore in fish body is removed in exploitation, the medicine of noxious substance seems urgent and important.
CN 104381641 A discloses a kind of freshwater fish & shrimp preventing disease, detoxicating feedstuff, and the weight portion of its constitutive material is: beautiful Rice flour 140-150, Testa Tritici 120-130, fermented blood meal 70-80, tenebrio molitor powder 20-30, Oleum Glycines 15-25, Apple Seeds powder 8-10, Algae 15-20, Herba Spirodelae 10-15, Folium Nelumbinis 10-15, stem or leaf of cattail 8-12, Herba vallisneriae Spiralis 8-10, Folium Allium sativum L 5-8, Poria 2-3, Rhizoma Osmundae 2-3, chaste tree Mustard 1-2, Rhizoma Coptidis 1-2, Radix Et Rhizoma Rhei 0.5-1, Radix Scutellariae 1-2, soy sauce 5-7, Sal 3-4, Herba Alii fistulosi powder 2-3, Os Sus domestica soup 20-30, Carapax Eriocheir sinensis powder 2-3, bone meal 1-2, antidote 4-6.The weight portion of described its constitutive material of antidote is: kieselguhr 15-20, Kaolin 10- 15, attapulgite 10-15, zeolite powder 8-12, montmorillonite powder 5-8, Gypsum Fibrosum powder 2-3, lignocellulose 15-25, activated carbon powder 20- 30, chitosan 8-10, Radix Stemonae powder 8-10, chilli seed powder 2-3.This feedstuff is swelling product, utilizes the absorption of antidote, removing toxic substances to make With, absorb the harmful poisonous substances such as colibacillus, enterotoxin and heavy metal ion in fish and shrimp body, and purify water, strengthen water Breathability, increase water body dissolved oxygen amount.In feedstuff, the Poria of interpolation, Rhizoma Osmundae, Herba Schizonepetae, Rhizoma Coptidis, Radix Et Rhizoma Rhei, Radix Scutellariae play antibacterial killing Worm effect.Therefore this invention provides and utilizes the principle adsorbed to be adsorbed by the poisonous substance in fish and shrimp body, and excretes, Toxic Matter is back to again in water body, also can return once again in fish and shrimp body, thus can not really remove noxious substance in fish and shrimp body, no Can ensure that in fish and shrimp meat product without noxious substance.
Summary of the invention
In order to overcome prior art defect, noxious substance in real removing fish body, it is ensured that do not contain poisonous substance in processed fish meat products Matter, the present invention provides a kind of and removes the medicine of noxious substance in fish body.
The present invention removes the medicine of noxious substance in fish body, be the raw extract by following mass parts with activated carbon, The swelling product that cyclodextrin, puffing material are made: Radix Bupleuri: 20 ~ 70, Radix Et Rhizoma Rhei: 20 ~ 50, Folium Isatidis: 20 ~ 70, Herba Artemisiae Scopariae: 10 ~ 30, Fructus Forsythiae: 15 ~ 30, Herba Leonuri: 10 ~ 30;
Activated carbon dosage is 5 ~ 20 mass parts, and cyclodextrin consumption is 10 ~ 30 mass parts.
Preferably, the mass parts of raw material is: Radix Bupleuri: 40 ~ 60, Radix Et Rhizoma Rhei: 30 ~ 40, Folium Isatidis: 40 ~ 60, Herba Artemisiae Scopariae: 10 ~ 30, Fructus Forsythiae: 20 ~ 30, Herba Leonuri: 10 ~ 30.
It is further preferred that Radix Bupleuri: 50, Radix Et Rhizoma Rhei: 35, Folium Isatidis: 50, Herba Artemisiae Scopariae: 20, Fructus Forsythiae: 25, Herba Leonuri: 20.
In specific embodiments, described puffing material is selected from corn, beans, potato class, Semen Maydis.
Radix Bupleuri: meridian distribution of property and flavor: cold nature, bitter in the mouth, pungent, return Liver Channel, gallbladder meridian, tool depressed liver-energy dispersing and function of gallbladder promoting, dredge gas resolving depression, dissipate the merit of fire Effect.Preferably effect is all had to improving symptom, retraction liver spleen, recovery liver function and hepatitis B antigen negative conversion rate.
Radix Et Rhizoma Rhei rushes down exerts oneself to delay, eliminating fire and detoxication, function of gallbladder promoting, protects the liver.Radix Et Rhizoma Rhei is made by the following method: take the life being cut into small pieces big Huang, mixes thoroughly with yellow wine, steams in putting food steamer, or puts sealing in tank, sits in kettle, and Steam by water bath is saturating, and taking-up is dried.
Folium Isatidis: heat clearing away, removing toxic substances, removing heat from blood, hemostasis.Control epidemic febrile disease intenseness of heat excessive thirst, influenza, acute infectious hepatitis, Bacillary dysentery, acute gastroenteritis, acute pneumonia, erysipelas, spit blood, epistaxis, jaundice, dysentery, sore throat, aphtha, swollen ulcer drug.Treat acute Infectious hepatitis: the most notable to acute plain edition infectious hepatitis effect.Instant effect, most 3~10 after taking Folium Isatidis It disappears or substantially disappears, and hepatic function test recovers or is generally 2~20 days close to recuperator.Indican in Folium Isatidis, mouth Liver, kidney, muscle and gastrointestinal it is distributed mainly on after clothes.
Herba Artemisiae Scopariae has significant hepatoprotective effect, to Combined hepatitis A and B vaccine, icterohepatitis, has significant curative effect.There are function of gallbladder promoting, rush Enter bile secretion, increase the effect that in bile, cholic acid and bilirubin are discharged.And have expeling ascarid and suppress multiple pathogenic skin Fungus and the effect of antibacterial.Herba Artemisiae Scopariae water decoction has inducing action to mice liver enzyme.Owing to liver enzyme is in addition to participating in drug metabolism, also join With bile acid, bilirubin, class ester and the metabolism of some poisonous substance, therefore Herba Artemisiae Scopariae also have promote liver detoxification effect.
Fructus Forsythiae extract can effectively suppress the breeding of common spoilage organisms in environment, treats pulmonary abscess heat clearing away, detoxifies, eliminating stagnation, Detumescence.Fructus Forsythiae controls warm, erysipelas, macule, carbuncle and ulcer toxic swelling, scrofula, urine stranguria with urinary obstruction.
Herba Leonuri: " book on Chinese herbal medicine asks former ": heat clearing away, removing heat from blood, removing toxic substances.
Activated carbon plays the effect of absorption poisonous substance, but also can be to water oxygenation.
The effective ingredient of cyclodextrin packaging medicine, plays a protective role, and makes medicine produce slow release effect, can extend Drug effect, moreover it is possible to cover abnormal smells from the patient.
The above-mentioned composition of compatibility of the present invention, plays the effect of the strong liver of hepatoprotective, promotes liver detoxification, increases the generation of poisonous substance Thank.Swelling product can be bubbled through the water column, and attracts fish swimming to look for food.
In actual application, in the removal fish body of the use present invention, the medicine of noxious substance is after 3 ~ 5 days, and the liver of fish is by using Black color or corvinus before become scarlet, it was demonstrated that remove the effective instant effect of noxious substance in fish body.
On the other hand, the preparation method of the medicine of noxious substance in the present invention also provides for above-mentioned removal fish body.
This preparation method, comprises the steps:
1) raw material crushes respectively;
2) decocting three times together, merge the decocting liquid of three times, filter to get filtrate;
3) activated carbon, cyclodextrin, puffing material it are in harmonious proportion respectively with appropriate filtrate;
4) by residual filtrate and 3) stir together with gained, expanded granulation, packaging, obtain finished product.
Wherein, the consumption of puffing material makes swelling product as minimum can ensure that, can the most suitably increase.
Further, in step 1), it is crushed to 1 ~ 10mm.
In step 2), each decocting time is 1 ~ 3h;
In step 2), appropriate supplement water-filling during decocting, make up the moisture evaporated.
Detailed description of the invention
Embodiment 1
Raw materials quality part: Radix Bupleuri: 50, Radix Et Rhizoma Rhei: 35, Folium Isatidis: 50, Herba Artemisiae Scopariae: 20, Fructus Forsythiae: 25, Herba Leonuri: 20.
Puffing material selects tapioca starch.
Activated carbon dosage is 15 mass parts, and cyclodextrin consumption is 10 mass parts.
1) raw material is crushed to 1 ~ 10mm respectively;
2) decocting three times together, each decocting time is 2h;Appropriate supplement water-filling during decocting, makes up the moisture evaporated;Close And the decocting liquid of three times, filter to get filtrate;
3) activated carbon, cyclodextrin, puffing material it are in harmonious proportion respectively with appropriate filtrate;
4) by residual filtrate and 3) stir together with gained, expanded granulation, packaging, obtain finished product.
Embodiment 2
Raw materials quality part: Radix Bupleuri: 70, Radix Et Rhizoma Rhei: 50, Folium Isatidis: 70, Herba Artemisiae Scopariae: 20, Fructus Forsythiae: 25, Herba Leonuri: 20.
Puffing material selects Semen Maydis powder.
Activated carbon dosage is 15 mass parts, and cyclodextrin consumption is 10 mass parts.
1) raw material is crushed to 1 ~ 10mm respectively;
2) decocting three times together, each decocting time is 2h;Appropriate supplement water-filling during decocting, makes up the moisture evaporated;Close And the decocting liquid of three times, filter to get filtrate;
3) activated carbon, cyclodextrin, puffing material it are in harmonious proportion respectively with appropriate filtrate;
4) by residual filtrate and 3) stir together with gained, expanded granulation, packaging, obtain finished product.
Embodiment 3
Using embodiment 1 gained finished product, be sprinkling upon the water surface every morning, consumption is by fish body weight (gross weight of all fishes in fishpond) 1%, continue 3 ~ 5 days.Fish with a net to kill and cut liver, it is seen that the liver of fish is scarlet.
The most persistently throwing something and feeding 7 days, 10 days, fishing with a net to kill cuts liver, it is seen that the liver of fish is scarlet.But scarlet degree one Cause, lose and have significant change again, illustrate to continue to have reached effect in 3 ~ 5 days.

Claims (8)

1. remove the medicine of noxious substance in fish body, be the raw extract by following mass parts and activated carbon, cyclodextrin, expanded The swelling product that material is made: Radix Bupleuri: 20 ~ 70, Radix Et Rhizoma Rhei: 20 ~ 50, Folium Isatidis: 20 ~ 70, Herba Artemisiae Scopariae: 10 ~ 30, Fructus Forsythiae: 15 ~ 30, Herba Leonuri: 10 ~ 30;
Activated carbon dosage is 5 ~ 20 mass parts, and cyclodextrin consumption is 10 ~ 30 mass parts.
Medicine the most according to claim 1, it is characterised in that: the mass parts of raw material is: Radix Bupleuri: 40 ~ 60, Radix Et Rhizoma Rhei: 30 ~ 40, Folium Isatidis: 40 ~ 60, Herba Artemisiae Scopariae: 10 ~ 30, Fructus Forsythiae: 20 ~ 30, Herba Leonuri: 10 ~ 30.
Medicine the most according to claim 1, it is characterised in that: Radix Bupleuri: 50, Radix Et Rhizoma Rhei: 35, Folium Isatidis: 50, Herba Artemisiae Scopariae: 20, Fructus Forsythiae: 25, Herba Leonuri: 20.
Medicine the most according to claim 1, it is characterised in that: described puffing material is selected from corn, beans, potato class, Semen Maydis.
5. the preparation method of the medicine of noxious substance in the removal fish body described in any one of claim 1 ~ 4, comprises the steps:
1) raw material crushes respectively;
2) decocting three times together, merge the decocting liquid of three times, filter to get filtrate;
3) activated carbon, cyclodextrin, puffing material it are in harmonious proportion respectively with appropriate filtrate;
4) by residual filtrate and 3) stir together with gained, expanded granulation, packaging, obtain finished product.
Preparation method the most according to claim 5, it is characterised in that: in step 1), it is crushed to 1 ~ 10mm.
Preparation method the most according to claim 5, it is characterised in that: in step 2), each decocting time is 1 ~ 3h.
Preparation method the most according to claim 5, it is characterised in that: in step 2), appropriate supplement water-filling during decocting.
CN201610729161.3A 2016-08-26 2016-08-26 Medicine for removing toxic substances in fishes and preparation method of medicine Pending CN106309760A (en)

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101085054A (en) * 2007-06-26 2007-12-12 天津生机集团有限公司 Liver-nourishing powder containing bupleurum, rhubarb and other medicine for aquatic animals
CN103461718A (en) * 2013-09-27 2013-12-25 苏州市阳澄湖现代农业产业园特种水产养殖有限公司 Antiviral crucian feed and preparation method thereof
CN103989852A (en) * 2014-05-26 2014-08-20 湖州天健兽药有限公司 Veterinary traditional Chinese medicine for preventing and treating fish diseases
CN104106735A (en) * 2013-12-20 2014-10-22 江苏农牧科技职业学院 Environmentally-friendly snakehead fish feed containing Chinese herbal medicinal components, and preparation method thereof
CN104381641A (en) * 2014-10-31 2015-03-04 安徽华亿农牧科技发展有限公司 Disease prevention and detoxification feed for fish and shrimps in fresh water, and preparation method of feed

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101085054A (en) * 2007-06-26 2007-12-12 天津生机集团有限公司 Liver-nourishing powder containing bupleurum, rhubarb and other medicine for aquatic animals
CN103461718A (en) * 2013-09-27 2013-12-25 苏州市阳澄湖现代农业产业园特种水产养殖有限公司 Antiviral crucian feed and preparation method thereof
CN104106735A (en) * 2013-12-20 2014-10-22 江苏农牧科技职业学院 Environmentally-friendly snakehead fish feed containing Chinese herbal medicinal components, and preparation method thereof
CN103989852A (en) * 2014-05-26 2014-08-20 湖州天健兽药有限公司 Veterinary traditional Chinese medicine for preventing and treating fish diseases
CN104381641A (en) * 2014-10-31 2015-03-04 安徽华亿农牧科技发展有限公司 Disease prevention and detoxification feed for fish and shrimps in fresh water, and preparation method of feed

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