CN104222673A - Meat chicken breeding method for reducing morbidity of inclusion body hepatitis - Google Patents
Meat chicken breeding method for reducing morbidity of inclusion body hepatitis Download PDFInfo
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Abstract
The invention provides a meat chicken breeding method for reducing the morbidity of inclusion body hepatitis. The method comprises the following steps: feeding a 3-7-week meat chicken with a feed prepared from the following raw materials in percentage by mass: 57.4% of corns, 3% of bran, 20% of bean pulp, 2% of fish meal, 4% of rapeseed meal, 3% of cottonseed meal, 1% of calcium hydrogen phosphate, 0.3% of compound vitamin, 8% of stone powder, 0.3% of salt and 1% of a disease-resistant auxiliary material, wherein the disease-resistant auxiliary material comprises the following components: 90-130 g of each of eclipta alba, commelina communis and rabdosia lophanthide, 50-80 g of each of felwort, akebiaquinata, rhizoma cyperi, fructus aurantii, root of red-rooted salvia, radix rehmanniae praeparata, agrimonia pilosa and lalang grass rhizome, 30-60 g of each of rhizoma cibotii, golden cypress, houttuynia cordata, herba andrographitis, red halloysite, yam rhizome and lagotis brevituba maxim, and 25-50 g of liquorice. The method is simple; the feed is convenient to use, has a good effect of preventing and treating the inclusion body hepatitis of the chicken, and can remarkably reduce the loss of breeders due to the inclusion body hepatitis.
Description
technical field:
The present invention relates to chicken fowl cultural technique field, particularly relate to a kind of broiler breeding method reducing the inclusion body hepatitis incidence of disease.
background technology:
In the breeding process of chicken fowl, often cause chicken fowl dead because suffering from various disease, this treatment is too late, then bring huge economic loss to raiser, for chicken inclusion body hepatitis, principal character is that the young chicken group death rate increases suddenly, sick chicken severe anemia is hepatomegaly, hemorrhage and downright bad.Inclusion body is had in visible liver cell nuclear.This disease is also known as anaemia syndrome.It is caused by FAV, hemorrhage with liver, severe anemia, jaundice, and hemorrhage of muscle and the death rate increase suddenly, and in liver cell, form the infectious disease that intranuclear inclusion is feature.The cause of disease of pathogenic characteristic chicken inclusion body hepatitis is the I group I fowl adenovirus of Adenoviridae.Virion is without cyst membrane, and diameter is 70-90 nanometers, and nucleic acid is distrand DNA.Virus, in endoreduplication, produces basophil inclusion bodies.Have resistance to ether, chloroform, trypsase, 5% ethanol, susceptible animal only has chicken susceptible, and broiler chicken is multiple.Age of onset mostly occurs at the broiler chicken in 3 ~ 7 week age, and laying hen also occasionally has generation.The sick chicken of the infection sources, be with malicious chicken.Virus is discharged virus by ight soil, tracheae and nose and infects healthy chicken.Route of transmission is mainly infected through respiratory tract, alimentary canal and eye conjunctiva, is also transmitted to the next generation by kind of an egg.Occur more with spring and summer.Chicken of recovering can obtain lifetime immunity.
Sick chicken cuts open inspection, and liver is pale, matter is crisp, swelling, liver, bone, skeletal muscle have point-like or ecchymosis.Inclusion body is had in liver cell, rounded.Kidney, splenomegaly, the swelling of kidney height, in canescence.Clinicopathologia main manifestations is liver enlargement, and in khaki, matter is crisp, and there is hemorrhage spot in various degree on surface, the necrosis region sometimes differed in size as seen.Some cases can see bone marrow lesion, and femur bone marrow is hemorrhage in pink, meanwhile, chest muscle and leg flesh pale and have hemorrhage spot, hypodermis, adipose tissue and intestines serous coat, mucous membrane are obviously hemorrhage as seen.Through 1 ~ 2 day incubation period of chicken of natural infection, it is dead that initial stage loses any symptom, after 2 ~ 3 days, the sick chicken spirit of minority is depressed, drowsiness, wattle is faded, skin is yellow, subcutaneous have hemorrhage, have water sample loose stool once in a while, within 3 ~ 5 days, reach peak mortality, the death rate reaches 15-30%, continue after 3 ~ 5 days, stop gradually.This disease incubation period, be generally no more than 4 days, in Young cock group, morbidity rapidly, often occurs dead chicken suddenly.Sick chicken heating, down in spirits, poor appetite, diarrhea, drowsiness, feather is fluffy and disorderly, and bent leg is squatted vertical.The sick chicken of minority presents jaundice symptom.The young chicken in 4 ~ 10 week age, if in both feet paralysis, what before have on one's deathbed sends calling, and occurs the nervous symptoms such as head back to arch, be then usually that anaemia and spirit are depressed, the course of disease is 10 ~ 14 days.When the chicken in discontented 5 week age infects, generally can be completely recovered to during 8 week age.The incidence of disease can up to 100%, and the death rate is not from 2% to 10% etc., sometimes can reach 30% ~ 40%.Infect 1 of this disease, Japanese instar chickling presents severe anemia symptom.
At present very effective therapy be there is no to chicken inclusion body hepatitis, therefore, mainly with putting prevention first in breeding process, the chicken house of this disease occurring, in feed, adding B B-complex and trace element.Conventional methods for the treatment of as, the clear spice of sense poison, 3% glucose+vitamin C drinking-water.Also can endure water with Ganshenkang (composition is: Radix Isatidis, the Radix Astragali, barrenwort, folium isatidis, Radix Glycyrrhizae etc.), in the ratio that is watered of liquid medicine ratio 1 ︰ more than 8, slow fire boils, boil latter 15 minutes, leach concoction, be blended into proper amount of clear water, be used in conjunction 4 ~ 5 days, use 3% glucose+vitamin C drinking-water simultaneously.Method disclosed in other, such as paper " brief talking the diagnosis and treatment of chicken inclusion body hepatitis ", it discloses several groups of therapeutic schemes, as astragalus polyose+beneficial liver protects kidney: be used in conjunction 3 days ~ 5 days.Medication every day 6 hours, once-a-day, changes clear water after 6 hours.PHA+ Ribavirin+strong+3% glucose of bodyguard spy, is used in conjunction 4 days.Chinese medicine preparation: folium isatidis 60 g, oriental wormwood 30 g, cape jasmine 45 g, giant knotweed 30 g, rheum officinale 20 g, Asiatic plantain 35 g, every 100 kg feeds mix 0.5 ~ 1.0 kg, and control scabies secondary infection, to reduce death.Concrete methods for the treatment of (can often prop up 2 milliliters with vitamin C injection; containing 0.1 milligram); Vitamin K3, K4 injection (often propping up 1 milliliter, containing 4 milligrams); gentamicin (often props up 1 milliliter; containing 20 milligrams) each 1, to cold water 250 milliliters, allow disease chicken freely drink; 1 week course for the treatment of, drug withdrawal 3 days; Change cold water 250 milliliters, allow disease chicken freely drink, 1 week course for the treatment of, drug withdrawal 3 days; Change cold water 500 milliliters, drink drug withdrawal after 1 week.After oriental wormwood 600g, rheum officinale 300g, cape jasmine 300g decoct 2h, filtering extracting liquid is blended in 200kg water, freely drinks.
By the retrieval of above-mentioned prior art, can find, at present for the treatment Chinese medicine of inclusion body hepatitis, Western medicine has certain effect, but Western medicine majority is conventional disease-resistant medicine, multiple chicken poultry diease all can be general, cause the chicken fowl resistance to the action of a drug to increase, and medicament residue is higher, is unfavorable for the edible safety of people.Therefore, some Chinese medicine substitutes have been there are, as Chinese patent application 2009101665868 discloses a kind of Chinese herbal feed additive for prevention and therapy chicken liver lesion, its component is the root of large-flowered skullcap 50 parts, the coptis 25 parts, golden cypress 60 parts, rhizoma atractylodis macrocephalae 60 parts, felwort 70 parts, plantain seed 80 parts, radix bupleuri 40 parts, Radix Angelicae Sinensis 40 parts, radix rehmanniae recen 60 parts, 60 parts, Poria cocos, cordate houttuynia 80 parts, chrysanthemum 40 parts, 50 parts, Radix Glycyrrhizae.And for example Chinese patent application 2010102703573 discloses a kind of Chinese herbal feed additive for prevention and therapy chicken liver lesion: the raw medicinal material chosen and composition by weight thereof respectively: Huang Cen 15 parts, the coptis 15 parts, felwort 10 parts, cordate houttuynia 10 parts, Asiatic plantain 12 parts, radix rehmanniae recen 15 parts, chrysanthemum 7 parts, Radix Isatidis 8 parts.Its preparation method is, mixes after pulverizing after the mixing of above-mentioned raw materials medicinal material or pulverizing respectively.And for example Chinese patent application 2013100743847 discloses a kind of traditional Chinese medicine oral liquid for the treatment of chicken inclusion body hepatitis, and its constituent is: folium isatidis 13-17g, glue stock blue 13-17g, notopterygium root 8-12g, Asiatic plantain 8-12g, cape jasmine 8-12g, root of purple-flowered peucedanum 8-12g, Radix Astragali 3-7g, giant knotweed 3-7g, Poria cocos 3-7g, honeysuckle 3-7g, indigo naturalis 3-7g, hay 3-7g.
On the basis of existing technology, provide a kind of method simple, easy to use, prevention and cure chicken inclusion body hepatitis is effective, obviously can reduce the cultural method of the laying hen of the loss that therefore illness is brought to raiser for purport of the present invention.
summary of the invention:
The object of the invention is to overcome the shortcoming existed in prior art, provide a kind of method simple, easy to use, prevention and cure chicken inclusion body hepatitis is effective, obviously can reduce the cultural method of the laying hen of the loss that therefore illness is brought to raiser.
To achieve these goals, the invention provides a kind of broiler breeding method reducing the inclusion body hepatitis incidence of disease, wherein, operate in accordance with the following steps:
Broiler chicken, when 3-7 age in week, carries out feeding by following mass percent configuration feed: corn 57.4%, wheat bran 3%, dregs of beans 20%, fish meal 2%, the dish dregs of rice 4%, cotton dregs 3%, calcium monohydrogen phosphate 1%, B B-complex 0.3%, stone flour 8%, salt 0.3%, disease-resistant auxiliary material 1%;
The component of described disease-resistant auxiliary material is: Eclipta prostrata, Commelina communis, each 90-130g of rabdosia lophanthide, felwort, akebi, rhizoma cyperi, Fructus Aurantii, the red sage root, cultivated land, hairyvein agrimony, each 50-80g of cogongrass rhizome, rhizoma cibotii, golden cypress, cordate houttuynia, Herba Andrographitis, red halloysite, Bi moss, each 30-60g of Lagotis glauca, Radix Glycyrrhizae 25-50g;
Time prepared by disease-resistant auxiliary material: after said components is mixed, with water extract method lixiviate three times, after three times leaching liquor merges, boiling obtains mixture of viscous form, adds modified starch, CMC and sweetener; Modified starch, CMC and sweetener mass ratio are 4:1:0.5, the quality of modified starch, CMC and sweetener and be the 1-1.5% of mixture of viscous form quality, stir, obtain pulvis after drying, pulvis is after ultraviolet irradiation is sterilized 10 seconds, add powdered glucose and gentamicin sulphate powder, the mass ratio of powdered glucose and gentamicin sulphate powder is 3:1, the quality of the powdered glucose added and gentamicin sulphate powder and be 1% of pulvis quality, obtains disease-resistant auxiliary material after mixing.
Or, the component of disease-resistant auxiliary material is: Eclipta prostrata, Commelina communis, each 90-110g of rabdosia lophanthide, felwort, akebi, rhizoma cyperi, Fructus Aurantii, the red sage root, cultivated land, hairyvein agrimony, each 50-70g of cogongrass rhizome, rhizoma cibotii, golden cypress, cordate houttuynia, Herba Andrographitis, red halloysite, Bi moss, each 30-50g of Lagotis glauca, Radix Glycyrrhizae 25-40g.
Or, the component of disease-resistant auxiliary material is: Eclipta prostrata, Commelina communis, each 110-130g of rabdosia lophanthide, felwort, akebi, rhizoma cyperi, Fructus Aurantii, the red sage root, cultivated land, hairyvein agrimony, each 70-80g of cogongrass rhizome, rhizoma cibotii, golden cypress, cordate houttuynia, Herba Andrographitis, red halloysite, Bi moss, each 50-60g of Lagotis glauca, Radix Glycyrrhizae 40-50g.
Or, the component of disease-resistant auxiliary material is: Eclipta prostrata, Commelina communis, each 95-125g of rabdosia lophanthide, felwort, akebi, rhizoma cyperi, Fructus Aurantii, the red sage root, cultivated land, hairyvein agrimony, each 55-75g of cogongrass rhizome, rhizoma cibotii, golden cypress, cordate houttuynia, Herba Andrographitis, red halloysite, Bi moss, each 35-55g of Lagotis glauca, Radix Glycyrrhizae 30-45g.
Further, add Vitamin K3 in the feed of configuration, the amount added is that feed per ton is no more than 5g.(optional)
Vitamin k 3, Chinese name, menadione; Menadione sodium bisulfite; 2-MNQ; Vitamin K3 is the required material of liver synthesis protoenzyme (factor B), and participates in proconvertin, IX, and the synthesis of X, maintains the blood clotting physiology course of animal.The K that is deficient in vitamin can cause above-mentioned clotting factor dyssynthesis, affects coagulation process and causes bleeding.Vitamin K is also required by the vitamin K dependence carboxylation system (mainly referring to be present in the histoorgans such as liver, bone, testis, skin and kidney) in animal body, is the indispensable factor in bone element (BGP) building-up process.In addition, in energy-rich compound metabolism and oxidative phosphorylation process, and all play an important role with the aspect of other liposoluble vitamin metabolism, and there is diuresis, enhancing liver detoxification function, participate in the structure of film, the function reduced blood pressure.
Disease-resistant auxiliary material of the present invention, adopts the preparation method of Chinese patent drug, and the present invention is with the Eclipta prostrata of removing toxic substances, and antitoxin Commelina communis, the rabdosia lophanthide of removing jaundice clearing damp is monarch drug in a prescription.With clearing liver dampness removing to medicine felwort, akebi; Soothing the liver promoting the circulation of qi to medicine rhizoma cyperi, Fructus Aurantii, increase hematopoietic potential, increase the medicine red sage root, the cultivated land of erythrocyte and hemoglobin, there is the hairyvein agrimony of hemostatic function, cogongrass rhizome is ministerial drug.With the rhizoma cibotii of increased platelets counts content, golden cypress, increase the cordate houttuynia of leukocytes phagocytic ability, Herba Andrographitis, the red halloysite of removing toxic substances, Bi moss, antitoxin Lagotis glauca is adjutant.Be in harmonious proportion the property of medicine as making medicine using Radix Glycyrrhizae.Meanwhile, use modified starch, CMC and sweetener seasoning, use powdered glucose and gentamicin sulphate powder (for animals) to increase effect.
Treat the sick chicken of the inclusion body hepatitis of having fallen ill, disease-resistant auxiliary material is added water modulation quality than 8-12%, often only gavages 5-10ml, 2 times on the one, gavage 3 continuously, Be very effective.
Advantage of the present invention is: method is simple, and easy to use, prevention and cure chicken inclusion body hepatitis is effective, obviously can reduce the loss that therefore illness is brought to raiser.Be specially, in the high period of disease of broiler chicken, disease-resistant auxiliary material mixed in feed and carries out feeding, increase resistance against diseases.For the sick chicken of ill inclusion body hepatitis, disease-resistant auxiliary material bath is gavaged and treats.
detailed description of the invention:
Reduce the broiler breeding method of the inclusion body hepatitis incidence of disease, wherein, operate in accordance with the following steps:
Broiler chicken, when 3-7 age in week, carries out feeding by following mass percent configuration feed: corn 57.4%, wheat bran 3%, dregs of beans 20%, fish meal 2%, the dish dregs of rice 4%, cotton dregs 3%, calcium monohydrogen phosphate 1%, B B-complex 0.3%, stone flour 8%, salt 0.3%, disease-resistant auxiliary material 1%;
The component of described disease-resistant auxiliary material is: Eclipta prostrata, Commelina communis, each 90-130g of rabdosia lophanthide, felwort, akebi, rhizoma cyperi, Fructus Aurantii, the red sage root, cultivated land, hairyvein agrimony, each 50-80g of cogongrass rhizome, rhizoma cibotii, golden cypress, cordate houttuynia, Herba Andrographitis, red halloysite, Bi moss, each 30-60g of Lagotis glauca, Radix Glycyrrhizae 25-50g;
Time prepared by disease-resistant auxiliary material: after said components is mixed, with water extract method lixiviate three times, after three times leaching liquor merges, boiling obtains mixture of viscous form, adds modified starch, CMC and sweetener; Modified starch, CMC and sweetener mass ratio are 4:1:0.5, the quality of modified starch, CMC and sweetener and be the 1-1.5% of mixture of viscous form quality, stir, obtain pulvis after drying, pulvis is after ultraviolet irradiation is sterilized 10 seconds, add powdered glucose and gentamicin sulphate powder, the mass ratio of powdered glucose and gentamicin sulphate powder is 3:1, the quality of the powdered glucose added and gentamicin sulphate powder and be 1% of pulvis quality, obtains disease-resistant auxiliary material after mixing.
Or, the component of disease-resistant auxiliary material is: Eclipta prostrata, Commelina communis, each 90-110g of rabdosia lophanthide, felwort, akebi, rhizoma cyperi, Fructus Aurantii, the red sage root, cultivated land, hairyvein agrimony, each 50-70g of cogongrass rhizome, rhizoma cibotii, golden cypress, cordate houttuynia, Herba Andrographitis, red halloysite, Bi moss, each 30-50g of Lagotis glauca, Radix Glycyrrhizae 25-40g.
Or, the component of disease-resistant auxiliary material is: Eclipta prostrata, Commelina communis, each 110-130g of rabdosia lophanthide, felwort, akebi, rhizoma cyperi, Fructus Aurantii, the red sage root, cultivated land, hairyvein agrimony, each 70-80g of cogongrass rhizome, rhizoma cibotii, golden cypress, cordate houttuynia, Herba Andrographitis, red halloysite, Bi moss, each 50-60g of Lagotis glauca, Radix Glycyrrhizae 40-50g.
Or, the component of disease-resistant auxiliary material is: Eclipta prostrata, Commelina communis, each 95-125g of rabdosia lophanthide, felwort, akebi, rhizoma cyperi, Fructus Aurantii, the red sage root, cultivated land, hairyvein agrimony, each 55-75g of cogongrass rhizome, rhizoma cibotii, golden cypress, cordate houttuynia, Herba Andrographitis, red halloysite, Bi moss, each 35-55g of Lagotis glauca, Radix Glycyrrhizae 30-45g.
Further, add Vitamin K3 in the feed of configuration, the amount added is that feed per ton is no more than 5g.(optional)
Treat the sick chicken of the inclusion body hepatitis of having fallen ill, disease-resistant auxiliary material is added water modulation quality than 8-12%, often only gavages 5-10ml, 2 times on the one, gavage 3 continuously, Be very effective.
Example 1:
Zhu Qiao town, Laizhou City Qiu Jia plant:
Broiler chicken, when 3-7 age in week, carries out feeding by following mass percent configuration feed: corn 57.4%, wheat bran 3%, dregs of beans 20%, fish meal 2%, the dish dregs of rice 4%, cotton dregs 3%, calcium monohydrogen phosphate 1%, B B-complex 0.3%, stone flour 8%, salt 0.3%, disease-resistant auxiliary material 1%; After mixing feed feeding on the one 3-4 time.
The component of described disease-resistant auxiliary material is: Eclipta prostrata, Commelina communis, each 130g of rabdosia lophanthide, felwort, akebi, rhizoma cyperi, Fructus Aurantii, the red sage root, cultivated land, hairyvein agrimony, each 80g of cogongrass rhizome, rhizoma cibotii, golden cypress, cordate houttuynia, Herba Andrographitis, red halloysite, Bi moss, each 60g of Lagotis glauca, Radix Glycyrrhizae 50g;
Time prepared by disease-resistant auxiliary material: after said components is mixed, with water extract method lixiviate three times, after three times leaching liquor merges, boiling obtains mixture of viscous form, adds modified starch, CMC and sweetener; Modified starch, CMC and sweetener mass ratio are 4:1:0.5, the quality of modified starch, CMC and sweetener and be the 1-1.5% of mixture of viscous form quality, stir, obtain pulvis after drying, pulvis is after ultraviolet irradiation is sterilized 10 seconds, add powdered glucose and gentamicin sulphate powder, the mass ratio of powdered glucose and gentamicin sulphate powder is 3:1, the quality of the powdered glucose added and gentamicin sulphate powder and be 1% of pulvis quality, obtains disease-resistant auxiliary material after mixing.
For the sick chicken of the inclusion body hepatitis of morbidity, use disease-resistant auxiliary material to add water after morbidity and be configured to the solution of mass percent 12%, often only gavage 10ml.
Example 2
Changqing District, Jinan king family raiser:
Broiler chicken, when 3-7 age in week, carries out feeding by following mass percent configuration feed: corn 57.4%, wheat bran 3%, dregs of beans 20%, fish meal 2%, the dish dregs of rice 4%, cotton dregs 3%, calcium monohydrogen phosphate 1%, B B-complex 0.3%, stone flour 8%, salt 0.3%, disease-resistant auxiliary material 1%; Obtain feed after mixing, add Vitamin K3, the amount added is no more than 5g per ton.Feeding 3-4 time on the one.
The component of described disease-resistant auxiliary material is: Eclipta prostrata, Commelina communis, each 120g of rabdosia lophanthide, felwort, akebi, rhizoma cyperi, Fructus Aurantii, the red sage root, cultivated land, hairyvein agrimony, each 70g of cogongrass rhizome, rhizoma cibotii, golden cypress, cordate houttuynia, Herba Andrographitis, red halloysite, Bi moss, each 50g of Lagotis glauca, Radix Glycyrrhizae 40g;
Time prepared by disease-resistant auxiliary material: after said components is mixed, with water extract method lixiviate three times, after three times leaching liquor merges, boiling obtains mixture of viscous form, adds modified starch, CMC and sweetener; Modified starch, CMC and sweetener mass ratio are 4:1:0.5, the quality of modified starch, CMC and sweetener and be the 1-1.5% of mixture of viscous form quality, stir, obtain pulvis after drying, pulvis is after ultraviolet irradiation is sterilized 10 seconds, add powdered glucose and gentamicin sulphate powder, the mass ratio of powdered glucose and gentamicin sulphate powder is 3:1, the quality of the powdered glucose added and gentamicin sulphate powder and be 1% of pulvis quality, obtains disease-resistant auxiliary material after mixing.
For the sick chicken of the inclusion body hepatitis of morbidity, use disease-resistant auxiliary material to add water after morbidity and be configured to the solution of mass percent 10%, often only gavage 10ml.
Example 3
Qingdao Tianrui Ecological Technology Co., Ltd. (the applicant):
Broiler chicken, when 3-7 age in week, carries out feeding by following mass percent configuration feed: corn 57.4%, wheat bran 3%, dregs of beans 20%, fish meal 2%, the dish dregs of rice 4%, cotton dregs 3%, calcium monohydrogen phosphate 1%, B B-complex 0.3%, stone flour 8%, salt 0.3%, disease-resistant auxiliary material 1%; Obtain feed after mixing, add Vitamin K3, the amount added is no more than 5g per ton.Feeding 3-4 time on the one.
The component of described disease-resistant auxiliary material is: Eclipta prostrata, Commelina communis, each 110g of rabdosia lophanthide, felwort, akebi, rhizoma cyperi, Fructus Aurantii, the red sage root, cultivated land, hairyvein agrimony, each 60g of cogongrass rhizome, rhizoma cibotii, golden cypress, cordate houttuynia, Herba Andrographitis, red halloysite, Bi moss, each 40g of Lagotis glauca, Radix Glycyrrhizae 35g;
Time prepared by disease-resistant auxiliary material: after said components is mixed, with water extract method lixiviate three times, after three times leaching liquor merges, boiling obtains mixture of viscous form, adds modified starch, CMC and sweetener; Modified starch, CMC and sweetener mass ratio are 4:1:0.5, the quality of modified starch, CMC and sweetener and be the 1-1.5% of mixture of viscous form quality, stir, obtain pulvis after drying, pulvis is after ultraviolet irradiation is sterilized 10 seconds, add powdered glucose and gentamicin sulphate powder, the mass ratio of powdered glucose and gentamicin sulphate powder is 3:1, the quality of the powdered glucose added and gentamicin sulphate powder and be 1% of pulvis quality, obtains disease-resistant auxiliary material after mixing.
For the sick chicken of the inclusion body hepatitis of morbidity, use disease-resistant auxiliary material to add water after morbidity and be configured to the solution of mass percent 8%, often only gavage 10ml.
Above-mentioned 3 list of examples compare, (for the incidence of disease after the control of inclusion body hepatitis, after treatment efficient).
Example 1-3 respectively selects each 500 of the broiler chicken in 6 week age, select the broiler chicken 500 in 6 week age only as a control group from Qingdao Lan Yingqin industry Science and Technology Ltd. simultaneously, respectively sick chicken 10 inputs suffering from inclusion body hepatitis are raised together with, carry out infecting experiment, observe after 3 days, then the sick chicken of the inclusion body hepatitis of having fallen ill is treated, control group uses vitamin C injection (often to prop up 2 milliliters, containing 0.1 milligram), Vitamin K3, K4 injection (often props up 1 milliliter, containing 4 milligrams), gentamicin (often props up 1 milliliter, containing 20 milligrams) each 1, to cold water 250 milliliters, disease chicken is allowed freely to drink.
By upper table, can find, the cultural method of the application, effectively can reduce the probability of inclusion body hepatitis morbidity in breeding process.And can find the aqueous solution of 12% mass ratio of the application's disease-resistant drug, result for the treatment of is good.
Contrast experiment's data:
Animal used as test, chooses and invades then through the sick chicken of inclusion body hepatitis, determine the broiler chicken 1000 in 4 week age of catching an illness, be divided into 5 groups at random,
1 group of solution using 8% of the disease-resistant auxiliary material bath configuration of the embodiment of the present application 1, every day gavages 5ml, every day twice,
2 groups use prior art Chinese patent application 2013100743847 to disclose a kind of traditional Chinese medicine oral liquid for the treatment of chicken inclusion body hepatitis.
3 groups use in prior art, and Chinese medicine preparation: folium isatidis 60 g, oriental wormwood 30 g, cape jasmine 45 g, giant knotweed 30 g, rheum officinale 20 g, Asiatic plantain 35 g, every 100 kg feeds mix 0.5 ~ 1.0 kg.
4 groups, Chinese patent application 2010102703573 is used to disclose a kind of Chinese herbal feed additive for prevention and therapy chicken liver lesion.
5 groups use in background technology, the clear spice of sense poison, 3% glucose+vitamin C drinking-water.
Comparison therapy effect, the treatment of each group is after 4 days, and the record death rate and body weight contrast, continue feeding after 10 days, compare the time of recovering normal type.Image data is listed as follows
6 groups of healthy broiler chicken selecting 4 week age, for comparison weight recovery time (respectively organize differ be less than 10g with 6 namely calculate the normal value returning back to 6 groups), 6 groups as Normal group.
By upper table contrast, can find, the application's cure rate is high, result for the treatment of for inclusion body hepatitis is remarkable, and treatment required time is short, and the time of recovering body weight is fast, the death rate, lower than other schemes of the prior art, significantly can reduce raiser's therefore sick loss brought.
The toxicity test result of the disease-resistant auxiliary material of example 3 of the present invention:
Toxicity is to the experiment of rat:
Acute oral (LD50) > 500mg/kg,
It is acute through skin (LD50) > 2000mg/kg,
Belong to low toxicity.
Antiviral breeding data:
Get a sick chicken and do not do any treatment, as virus control;
Above-mentioned 1-6 group, often group randomly draws one on the 4th day what treat, fixing after taking body weight, dissects, and gets liver and calculates liver exponential quantity, calculates liver index inhibiting rate.
Heavy (g)/body weight (g) × 100 of liver index=liver
Liver index inhibiting rate=(virus control group liver Mean value of index-experimental group liver Mean value of index)/virus control group liver Mean value of index × 100%
Liver index is larger, represents that liver pathological changes degree is serious,
Hepatic tissue 10% formaldehyde is fixed, and ethanol series is dewatered, and dimethylbenzene is transparent, FFPE, slice thickness 4-5 micron, and HE dyes, and observes blood lipid change with ordinary optical microscope, with the liver of Normal group as a comparison.
The impact (n=10) of liver's checking (virus is observed)
By above-mentioned contrast, the component of 1 group of the application good inhibiting rate can be had to virus.
Advantage of the present invention is: method is simple, and easy to use, prevention and cure chicken inclusion body hepatitis is effective, obviously can reduce the loss that therefore illness is brought to raiser.Be specially, in the high period of disease of broiler chicken, disease-resistant auxiliary material mixed in feed and carries out feeding, increase resistance against diseases.For the sick chicken of ill inclusion body hepatitis, disease-resistant auxiliary material bath is gavaged and treats.
Claims (5)
1. reduce a broiler breeding method for the inclusion body hepatitis incidence of disease, it is characterized in that, operate in accordance with the following steps:
Broiler chicken, when 3-7 age in week, carries out feeding by following mass percent configuration feed: corn 57.4%, wheat bran 3%, dregs of beans 20%, fish meal 2%, the dish dregs of rice 4%, cotton dregs 3%, calcium monohydrogen phosphate 1%, B B-complex 0.3%, stone flour 8%, salt 0.3%, disease-resistant auxiliary material 1%;
The component of described disease-resistant auxiliary material is: Eclipta prostrata, Commelina communis, each 90-130g of rabdosia lophanthide, felwort, akebi, rhizoma cyperi, Fructus Aurantii, the red sage root, cultivated land, hairyvein agrimony, each 50-80g of cogongrass rhizome, rhizoma cibotii, golden cypress, cordate houttuynia, Herba Andrographitis, red halloysite, Bi moss, each 30-60g of Lagotis glauca, Radix Glycyrrhizae 25-50g;
Time prepared by disease-resistant auxiliary material: after said components is mixed, with water extract method lixiviate three times, after three times leaching liquor merges, boiling obtains mixture of viscous form, adds modified starch, CMC and sweetener; Modified starch, CMC and sweetener mass ratio are 4:1:0.5, the quality of modified starch, CMC and sweetener and be the 1-1.5% of mixture of viscous form quality, stir, obtain pulvis after drying, pulvis is after ultraviolet irradiation is sterilized 10 seconds, add powdered glucose and gentamicin sulphate powder, the mass ratio of powdered glucose and gentamicin sulphate powder is 3:1, the quality of the powdered glucose added and gentamicin sulphate powder and be 1% of pulvis quality, obtains disease-resistant auxiliary material after mixing.
2. reduce the broiler breeding method of the inclusion body hepatitis incidence of disease according to claim 1, it is characterized in that,
The component of described disease-resistant auxiliary material is: Eclipta prostrata, Commelina communis, each 90-110g of rabdosia lophanthide, felwort, akebi, rhizoma cyperi, Fructus Aurantii, the red sage root, cultivated land, hairyvein agrimony, each 50-70g of cogongrass rhizome, rhizoma cibotii, golden cypress, cordate houttuynia, Herba Andrographitis, red halloysite, Bi moss, each 30-50g of Lagotis glauca, Radix Glycyrrhizae 25-40g.
3. reduce the broiler breeding method of the inclusion body hepatitis incidence of disease according to claim 1, it is characterized in that,
The component of described disease-resistant auxiliary material is: Eclipta prostrata, Commelina communis, each 110-130g of rabdosia lophanthide, felwort, akebi, rhizoma cyperi, Fructus Aurantii, the red sage root, cultivated land, hairyvein agrimony, each 70-80g of cogongrass rhizome, rhizoma cibotii, golden cypress, cordate houttuynia, Herba Andrographitis, red halloysite, Bi moss, each 50-60g of Lagotis glauca, Radix Glycyrrhizae 40-50g.
4. reduce the broiler breeding method of the inclusion body hepatitis incidence of disease according to claim 1, it is characterized in that, the component of described disease-resistant auxiliary material is:
Eclipta prostrata, Commelina communis, each 95-125g of rabdosia lophanthide, felwort, akebi, rhizoma cyperi, Fructus Aurantii, the red sage root, cultivated land, hairyvein agrimony, each 55-75g of cogongrass rhizome, rhizoma cibotii, golden cypress, cordate houttuynia, Herba Andrographitis, red halloysite, Bi moss, each 35-55g of Lagotis glauca, Radix Glycyrrhizae 30-45g.
5. reduce the broiler breeding method of the inclusion body hepatitis incidence of disease according to claim 1, it is characterized in that, add Vitamin K3 in the feed of configuration, the amount added is that feed per ton is no more than 5g.
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| CN108012990A (en) * | 2018-01-12 | 2018-05-11 | 涡阳县益群牧业有限公司 | A kind of cultural method of month chicken |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106135742A (en) * | 2016-07-27 | 2016-11-23 | 广西河池市明达特种养殖专业合作社 | A kind of disease-resistant feed of Gallus Domesticus and preparation method thereof |
| CN108012990A (en) * | 2018-01-12 | 2018-05-11 | 涡阳县益群牧业有限公司 | A kind of cultural method of month chicken |
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Application publication date: 20141224 |