CN103599251A - Production method of traditional Chinese medicine preparation toxin remover for preventing and treating mycotoxicosis - Google Patents
Production method of traditional Chinese medicine preparation toxin remover for preventing and treating mycotoxicosis Download PDFInfo
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- CN103599251A CN103599251A CN201310580187.2A CN201310580187A CN103599251A CN 103599251 A CN103599251 A CN 103599251A CN 201310580187 A CN201310580187 A CN 201310580187A CN 103599251 A CN103599251 A CN 103599251A
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Abstract
The invention discloses a production method of a traditional Chinese medicine preparation toxin remover for preventing and treating mycotoxicosis. The traditional Chinese medicine preparation toxin remover is characterized by comprising the following raw materials by weight percent: 7-9% of folium artemisiae argyi, 6-8% of mother chrysanthemum, 7-9% of dandelion, 7-9% of fordia cauliflora hemsl, 6-8% of oriental wormwood, 7-8% of sweet wormwood, 7-9% of derris eriocarpa how, 7-9% of sticktight, 5-7% of semen plantaginis, 6-8% of black nightshade, 6-7% of azadirachta indica and 8-9% of dried radix rehmanniae. The production method comprises the following steps: A, respectively cleaning, airing and crushing the above traditional Chinese medicine raw materials, sieving by a 300-mesh sieve, so as to obtain traditional Chinese medicine fine powders; B, respectively weighing traditional Chinese medicine fine powders according to the ratio, and mixing and stirring well; C, adding a proper amount of auxiliary material to dilute, and mixing well, so as to obtain a brown solid powdery product. The production method has the beneficial effects that the traditional Chinese medicine preparation toxin remover has specific adsorption capacity, can efficiently remove various mycotoxins in a target manner, and has a good effect on zearalenone, vomitoxin, aflatoxin, ochratoxin, fumagillin, T-2 toxin and the like in an oriented mode; the detoxification ability of the liver on the toxins can be improved; and the damage to an animal body caused by the toxins can be removed.
Description
Technical field
The invention belongs to Chinese medicine composition preparing technical field, especially a kind of poisoning clear production method of Chinese medicine preparation syphilis of mycotoxin of preventing and treating.
Background technology
At present in livestock and poultry cultivation in recurrent Animal diseases, because the disease that feed mold causes is more and more, more and more serious, summer and autumn particularly, directly affect the fertility performance index of animal, influencer culturist's benefit, traditional remove the mould dose of mycotoxin in can only adsorption feed, can not stop mycotoxin synthetic, reach the object of eradicating toxin, because traditional goes mould dose because mainly working by absorption, in the time of absorbing toxin, also adsorb other medicine of a part, affect the curative effect of medicine, therefore by meticulously selecting, chosen the mould resistant that Chinese medicine assortment that anti-mildew activity is stronger forms a kind of pure Chinese medicine, advantage with performance green Chinese drug residue free.
Summary of the invention
The object of the invention is to for the shortcoming of going mould dose of existence at present, a kind of poisoning clear production method of Chinese medicine preparation syphilis of mycotoxin of preventing and treating is provided.
The present invention is achieved by the following technical solutions: a kind of poisoning clear production method of Chinese medicine preparation syphilis of mycotoxin of preventing and treating, it is characterized in that: the raw material that described Chinese medicine preparation syphilis is clear forms meter by weight: Folium Artemisiae Argyi 7-9%, Flos Chrysanthemi Indici 6-8%, Herba Taraxaci 7-9%, F. cauliflora Hemsl. 7-9%, Herba Artemisiae Scopariae 6-8%, Herba Artemisiae Annuae 7-8%, native Radix Glycyrrhizae 7-9%, Herba Bidentis Bipinnatae 7-9%, Semen Plantaginis 5-7%, Herba Solani Nigri 6-8%, Azadirachta Indica A. 6-7%, Radix Rehmanniae 8-9%; Described production method comprises the following steps:
A: various raw material of Chinese medicine are cleaned, dried, and pulverize, by 300 mesh sieves, obtain various Chinese medicine fine powders.
B, take various Chinese medicine fine powders mixing and stirring in proportion.
C, add suitable adjuvant to dilute again, and mix homogeneously, sepia solid powdery finished product obtained.
Further, described adjuvant is Pulvis Talci, by weight: 8-10%.
The selected raw material character of the present invention:
(1) Folium Artemisiae Argyi: gas delicate fragrance, bitter in the mouth, has the blood of regulating the flow of vital energy, and by cold-damp, hemostasis, has treatment trusted subordinate cold type of pain, has loose bowels, the effect of dysentery.
(2) Flos Chrysanthemi Indici: nature and flavor are bitter, pungent, are slightly cold, and heat-clearing and toxic substances removing, detumescence, to staphylococcus aureus, diphtheria corynebacterium, streptococcus, bacillus pyocyaneus, puncture Shigella, influenza virus, all have inhibitory action.
(3) Herba Taraxaci: contain the multiple health-nutrition compositions such as taraxol, taraxacin, choline, organic acid, protein, fat, carbohydrate, trace element and vitamin, inulin in Herba Taraxaci plant, have the effects such as diuresis, cathartic, jaundice eliminating subcutaneous ulcer, function of gallbladder promoting.
(4) Semen Plantaginis: sweet, light, cold nature, clearing away heat and promoting diuresis, eliminating dampness by diuresis antidiarrheal, improving eyesight, eliminates the phlegm, and cures mainly edema distension, heat-damp in summer dysentery, conjunctival congestion is hidden from view, and expectorant heat syndrome cough is breathed heavily.
(5) F. cauliflora Hemsl.: mildly bitter flavor, promoting blood circulation to remove obstruction in the collateral, reducing swelling and alleviating pain, preventing phlegm from forming and stopping coughing.
(6) Herba Artemisiae Scopariae: clearing away heat-damp and promoting diuresis, antipyretic, have a significant hepatoprotective effect, the effect that in increase bile, cholic acid and bilirubin are discharged. can increase heart coronary flow, improve microcirculation, antiinflammatory, blood fat reducing, the effects such as blood pressure lowering, anticoagulation, diuresis is antipyretic relievings asthma, and drives away ascarid and suppresses the effect of multiple pathogenic dermatophytes and antibacterial.
(7) Herba Artemisiae Annuae: property bitter, acrid, cold, clearing away summer-heat, malaria cold and heat, jaundice due to damp-heat.
(8) native Radix Glycyrrhizae: cool in nature, sweet in the mouth, nontoxic, cure mainly: clearing away heat-damp and promoting diuresis, the subcutaneous ulcer of harnessing the Yellow River, pulmonary tuberculosis.
(9) Herba Bidentis Bipinnatae: warm in nature, bitter in the mouth, nontoxic, heat-clearing and toxic substances removing, dissipating blood stasis for subsidence of swelling.
(10) Herba Solani Nigri: cold in nature, bitter in the mouth, micro-sweet, slightly poisonous, has the effect of heat-clearing and toxic substances removing, promoting blood circulation to remove blood stasis, inducing diuresis to remove edema, eliminating phlegm and stopping cough.
(11) Azadirachta Indica A.: have insecticidal activity the highest be nimbin, be universally acknowledged wide spectrum, efficient, low toxicity, the easy insecticide of degraded, noresidue.
(12) Radix Rehmanniae: heat clearing away, promote the production of body fluid, moisturize, laxation, removing blood stasis with potent drugs, tissue regeneration promoting, pain relieving, the incised wound stasis of blood, removing heat from blood, anastalsis.
Effect experiment situation of the present invention:
1, experiment situation
Through clinical investigation, find, at hot and humid 7-8 month feedstuff and product, easily go mouldy, it is poisoning easily to there is mycotoxin in commercial meat bird, so this experimental selection is used this Chinese medicine preparation to prevent in advance at 1-20 age in days July, other medication programs and immune programme for children and matched group are in full accord, selecting No. 1, No. 2, No. 5, No. 6 hen houses is prophylactic experimental group, and No. 3, No. 7 house is treated experimental group for occurring after respiratory tract, and No. 4, No. 8 hen house is blank group.All hen houses enter 18000 of chickens, and breeding cycle is 42 days.
Table 1 experiment grouping
2, testing index and method
(1) daily jumpbogroup observation and pathology cut open inspection.
(2) day death rate.
(3) chicken counterpoise on the 20th.
Survival rate during (4) 20 age in days, feedstuff-meat ratio.
Deliver the feedstuff total amount of chicken gross weight/consumption for sale.
3, experimental result and analysis
(1) each hen house jumpbogroup observation and the chicken that dies of illness are cutd open inspection.
1,2,5, No. 6 hen houses, jumpbogroup situation is stable, and every day, mortality rate and material feeding situation were normal, and 3,4,7, No. 8 hen houses occur that at 8 ages in days mortality rate raises, and dissect and occur that muscular stomach seriously festers, and horny layer falls apart, and part has obvious ulcer kitchen range; The serious serious enlargement of case (fungal infection toxin kind is more) glandular stomach is ellipse or fusiformis, glandular stomach wall thickening, thelorrhagia, transparent swelling.Liver has irregular white or the downright bad point of canescence or necrosis region (causing groups of people's mistaken diagnosis for other hepatitis) more; Liver enlargement, part steatosis, above has tumor sclerosis; There is xanthochromia phenomenon; Have and be dark green (Salmonella sample liver); Be dark red etc.But major part occurs that the attenuation of liver edge, as blade, has mycete tuberosity on part liver.Spleen is " influenza spleen " sample, and enlargement, surperficial serous coat have a large amount of canescence necrosis regions.Sick chicken air bag thickens, and inside has cloud pathological changes; Mesentery changes roughly the same.There is obvious mycete tuberosity in part air bag, mesentery.Lungs change: become fibrinous pneumonia or hemorrhagic pneumonia more; The obvious atrophy of thymus, serious chicken occurs that thymus disappears, fabricius bursa atrophy degeneration (inside have pinkish-grey secretions, part is hemorrhage).Intestinal mucosa seriously comes off.3, No. 4 hen houses are used syphilis to treat clearly after there is Mycotoxicoses shape, using therapeutic dose after continuous three days, feed intake increases, and the chicken group mental status obviously person of outstanding talent takes a turn for the better, mortality rate obviously declines, and cuts open the pathological changes such as inspection glandular stomach, muscular stomach, liver, spleen and disappears.
(2) each hen house death rate
By death rate data, use syphilis prevention group clearly and treatment group all obviously to reduce death rate, illustrate that syphilis causes mycotoxin clearly in greatly property disease have extraordinary preventive and therapeutic action.
(3) counterpoise, survival rate, feedstuff-meat ratio experimental data
Each hen house of table 2. is delivered rear counterpoise, survival rate, feedstuff-meat ratio data for sale
From table 2, in body weight, survival rate prevention group > treatment group > blank group, feedstuff-meat ratio prevention group < treatment group < blank group, absolutely prove in the situation that the poisoning disease being caused by mycotoxin is at present more serious, use mycete for cultivation success or failure, to there is very crucial effect clearly.
Beneficial effect of the present invention: there is specific adsorption ability, the various mycotoxins of orientable efficient elimination, potent for 6-(10-hydroxy-6-oxo-trans-1-undecenyl)-.beta.-resorcylic acid lactone, vomitoxin, aflatoxin, Toxins,ochra., the bent toxin of cigarette and T-2 toxin etc., can improve the detoxification ability of the contratoxin of liver own, eliminate the infringement of toxin to animal body.
Accompanying drawing explanation
Accompanying drawing is each hen house death rate curve chart
Below in conjunction with specific embodiment, the present invention is further described.
the specific embodiment
Embodiment 1
Take and make 200 kg as example, Folium Artemisiae Argyi fine powder 18 kg wherein, Flos Chrysanthemi Indici fine powder 18 kg, Herba Taraxaci fine powder 18 kg, F. cauliflora Hemsl. fine powder 16 kg, Herba Artemisiae Scopariae fine powder 18 kg, Herba Artemisiae Annuae fine powder 18 kg, soil Radix Glycyrrhizae fine powder 16 kg, Herba Bidentis Bipinnatae fine powder 18 kg, Semen Plantaginis 14 kg, Herba Solani Nigri 14 kg, Azadirachta Indica A. 14 kg, the Radix Rehmanniae 18 kg, various raw material of Chinese medicine are cleaned, dry, pulverize rear by 300 order sieve, obtain various Chinese medicine fine powder mix homogeneously, then add the adjuvant Pulvis Talci of 20 kg to dilute, and mix homogeneously, obtain sepia pressed powder, carry out fill, obtain finished product.
Claims (2)
1. prevent and treat the poisoning clear production method of Chinese medicine preparation syphilis of mycotoxin for one kind, it is characterized in that: the raw material that described Chinese medicine preparation syphilis is clear forms meter by weight: Folium Artemisiae Argyi 7-9%, Flos Chrysanthemi Indici 6-8%, Herba Taraxaci 7-9%, F. cauliflora Hemsl. 7-9%, Herba Artemisiae Scopariae 6-8%, Herba Artemisiae Annuae 7-8%, native Radix Glycyrrhizae 7-9%, Herba Bidentis Bipinnatae 7-9%, Semen Plantaginis 5-7%, Herba Solani Nigri 6-8%, Azadirachta Indica A. 6-7%, Radix Rehmanniae 8-9%; Described production method comprises the following steps: A: various raw material of Chinese medicine are cleaned, dried, and pulverize, by 300 mesh sieves, obtain various Chinese medicine fine powders; B, take various Chinese medicine fine powders mixing and stirring in proportion; C, add suitable adjuvant to dilute again, and mix homogeneously, sepia solid powdery finished product obtained.
2. a kind of poisoning clear production method of Chinese medicine preparation syphilis of mycotoxin of preventing and treating according to claim 1, is characterized in that: described adjuvant is Pulvis Talci, by weight: 8-10%.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107927338A (en) * | 2017-11-27 | 2018-04-20 | 山东迅达康兽药有限公司 | A kind of medicine, its preparation method and the application of anti-mildew verticillium toxin |
| CN108514591A (en) * | 2018-04-27 | 2018-09-11 | 山东省花生研究所 | A kind of Chinese medicine preparation of degrading zearalenone, preparation method and application |
| CN110559346A (en) * | 2019-08-20 | 2019-12-13 | 沈惠萍 | Detoxifying tea |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101683116A (en) * | 2008-09-23 | 2010-03-31 | 张松灿 | Pure traditional Chinese medicine feed additive |
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101683116A (en) * | 2008-09-23 | 2010-03-31 | 张松灿 | Pure traditional Chinese medicine feed additive |
Non-Patent Citations (1)
| Title |
|---|
| 王素芬: "猪赤霉菌素中毒的综合防治", 《四川畜牧兽医》, vol. 31, no. 9, 30 September 2004 (2004-09-30), pages 48 - 49 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107927338A (en) * | 2017-11-27 | 2018-04-20 | 山东迅达康兽药有限公司 | A kind of medicine, its preparation method and the application of anti-mildew verticillium toxin |
| CN108514591A (en) * | 2018-04-27 | 2018-09-11 | 山东省花生研究所 | A kind of Chinese medicine preparation of degrading zearalenone, preparation method and application |
| CN110559346A (en) * | 2019-08-20 | 2019-12-13 | 沈惠萍 | Detoxifying tea |
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