CN101049370A - Preparation of Chinese traditional medicine for treating leucoderma - Google Patents
Preparation of Chinese traditional medicine for treating leucoderma Download PDFInfo
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- CN101049370A CN101049370A CN 200710099194 CN200710099194A CN101049370A CN 101049370 A CN101049370 A CN 101049370A CN 200710099194 CN200710099194 CN 200710099194 CN 200710099194 A CN200710099194 A CN 200710099194A CN 101049370 A CN101049370 A CN 101049370A
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Abstract
A Chinese medicine for treating leukoderma is prepared from more than 10 Chinese-medicinal materials including flatstem milkvetch seed, black sesame, dodder seed, spatholobus stem, etc. Its advantages are sure curative effect, high safety, and no toxic by effect.
Description
Technical field
The present invention relates to the leukodermic Chinese medicine preparation of a kind of treatment, is that a kind of vitiligo for the treatment of is the Chinese medicine preparation of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Vitiligo is a kind of posteriority limitation depigmentation dermatosis.Go down with skin color, bleach, boundary distinctness, no conscious sympton are feature.The same with other pigment anomalies, leukodermic sickness rate is with area, the ethnic group colour of skin and different.The dark more people's sickness rate of general colour is high more, and prevalence is about 0.1～2% in the population of China.The men and women can fall ill until old every year from the newborn baby about equally, but is many with teenager, has data to show that age of onset is in the majority 10～30 years old group, accounts for 62.65% of sum, and women's age of onset was than male about 5 years ahead of time.
Leukodermic clinical manifestation is: the skin at any position all can take place, but good sending out in being subject to solar radiation and frictionally damage position, as facial area, cervical region, trunk and extremity etc.The inboard mucosa of lip, labia, glans penis and foreskin also can involve.Most of leukasmus is symmetrically distributed, also has part patient white macula to distribute along nerve segment.Skin lesion is a limitation depigmentation speckle, milky, from fingernail to the coin size, circular, ellipse or irregular type.White macula place hair also can bleach.In progressive stage, the decolouring speckle is divided a word with a hyphen at the end of a line to normal skin, and development is very fast, and isomorphic response is arranged, and promptly can form the secondary vitiligo after pressure, friction, the wound.
Can divide three types according to leukoderma scope and distribution: 1, the topical type skin lesion is confined to a position, can be divided into 1. segmental pattern again: skin lesion is pressed dermatomere and is distributed; 2. mucosa type: only involve mucosa.2, general hair style is the most common, shows as skin lesion and is distributed widely in body surface, can be divided into 1. homeliness type: skin lesion is dispersed in and is distributed in the body surface many places; 2. face acra type: skin lesion is distributed in face and far-end of limb; 3. mixed type: above-mentioned several various combinations form.As face acra type+segmental pattern etc.3, whole body type, whole skin all decolour fully or almost, also have hair to bleach.
Primary disease is equivalent to leucoderma, the vitiligo of the traditional Chinese medical science.Put down in writing as " General Treatise on the Cause and Symptoms of Diseases " leucoderma: " the leucoderma person, face and neck health skin and flesh complexion changed are white, and be different with meat, the pain of also not itching, the leucoderma of meaning." and for example " the Yizong Jinjian surgery heart shows " vitiligo record: " vitiligo is the face collar humorously, and the ailment said due to cold or exposure white point speckle even all over of fighting does not mutually have the pain of itching, and controls and should fully recover from an illness by the pathogenic wind expelling fat liquoring.”
The traditional Chinese medical science thinks that leukodermic morbidity is outer because experience ailment said due to cold or exposure, injury from falling down; Interior because of feelings will internal injury, hemorrhagic disorder and consumption of essence etc., these can make qi-blood disharmony, and obstruction of collaterals by blood stasis, deficiency of the liver and kindey lead to this disease.So the treatment of the traditional Chinese medical science is to be divided into disease types such as disharmony between QI and blood, retention of damp-heat in the interior, obstruction of collaterals by blood stasis, deficiency of the liver and kindey, stagnation of QI due to depression of the liver to carry out Coryza Treated by Syndrome Differentiation.The leukodermic method of western medical treatment is a lot, but great majority can only reach recent clinical effectiveness, and can not prevent recurrence, and has toxic and side effects in various degree.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide the leukodermic Chinese medicine preparation of a kind of treatment.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by the following weight proportion raw material:
1.0～4 parts of 1.0～4 parts of Radixs Angelicae Dahuricae of 1.5～6 parts of Fructus Psoraleaes of Semen Astragali Complanati
1.0～4 parts of 1.0～4 parts of Radix Saposhnikoviaes of 1.5～6 portions of Caulis Spatholobis of Semen Sesami Nigrum
1.0～4 parts of 1.0～4 parts of Rhizoma Chuanxiongs of 1.5～6 parts of Radix Rehmanniae of Semen Cuscutae
0.1～2 part in 0.1～2 portion of Herba Spirodelae of 1.0～4 portions of Lignum Sappans of Radix Angelicae Sinensis
0.1～2 part of Fructus Tribuli
The weight proportion of each raw material of optimization formula of the present invention is:
1.5～2.5 parts of 1.5～2.5 parts of Radixs Angelicae Dahuricae of 2.5～3.5 parts of Fructus Psoraleaes of Semen Astragali Complanati
1.5～2.5 parts of 1.5～2.5 parts of Radix Saposhnikoviaes of 2.5～3.5 portions of Caulis Spatholobis of Semen Sesami Nigrum
1.5～2.5 parts of 1.5～2.5 parts of Rhizoma Chuanxiongs of 2.5～3.5 parts of Radix Rehmanniae of Semen Cuscutae
0.5～1.5 part in 0.5～1.5 portion of Herba Spirodelae of 1.5～2.5 portions of Lignum Sappans of Radix Angelicae Sinensis
0.5～1.5 part of Fructus Tribuli
The weight proportion of each raw material of optimum formula of the present invention is:
2 parts of 2 parts of Radixs Angelicae Dahuricae of 3 parts of Fructus Psoraleaes of Semen Astragali Complanati
2 parts of 2 parts of Radix Saposhnikoviaes of 3 portions of Caulis Spatholobis of Semen Sesami Nigrum
2 parts of 2 parts of Rhizoma Chuanxiongs of 3 parts of Radix Rehmanniae of Semen Cuscutae
1 part in 1 portion of Herba Spirodelae of 2 portions of Lignum Sappans of Radix Angelicae Sinensis
1 part of Fructus Tribuli
Drug action mechanism among the present invention is as follows:
The Semen Astragali Complanati nature and flavor are sweet, temperature.Return liver, kidney channel.Has the temperature compensation Liver and kidney, controlling nocturnal emission with astringent drugs, reducing urination, the effect that makes eye bright.Can treat lumbago due to renal deficiency, seminal emission premature ejaculation, nebulousurine leukorrhagia, dribbling urination, dizzy blurred vision etc.(the 145th page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
The Semen Sesami Nigrum property of medicine is sweet, and property is flat.Return the liver,spleen,kidney warp.Effect with nourish blood benefit essence, loosening bowel to relieve constipation.Can treat the dizziness and tinnitus due to the Liver and kidney asthenia of essence and blood, waist foot flaccidity is soft, early whitening of beard and hair, and scaly dry skin, the dryness of the intestine constipation, married woman's breast is few, carbuncle skin ulcer eczema, wind leprosy scrofula infections, infantile scrofula, burn, hemorrhoid etc.(the 3338th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Semen Cuscutae nature and flavor suffering, sweet, warm, flat.Return the liver,kidney,spleen warp.Have invigorating the liver and kidney, beneficial marrow, the smart effect of the benefit that makes eye bright.Can treat gastric cancer, osteocarcinoma, pulmonary carcinoma, nasopharyngeal carcinoma, soreness of waist and knee joint, impotence and seminal emission, quench one's thirst, dripping urination, order are dark, Light-headedness, visual deterioration, frequent fetal movement, frequent micturition etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 1066th page).
Fructus Psoraleae nature and flavor suffering, hardship, temperature.Return kidney, spleen channel.Have kidney invigorating and YANG supporting, the controlling nocturnal emission with astringent drugs reducing urination, warming spleen and stopping diarrha, the effect of improving inspiration by invigorating kidney-QI.Can treat that osteosarcoma, neoplastic bone shift, leukopenia, hemorrhagic illness, vitiligo, the cold diarrhea of suffering from a deficiency of the kidney, the enuresis, spermatorrhea, frequent micturition, sexual impotence, chills and pain of the waist and kness, frequent micturition, deficiency and coldness are breathed heavily and are coughed etc. behind the chemotherapy radiotherapy.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 714th page).
Caulis Spatholobi nature and flavor hardship, sweet, warm.Return liver, kidney channel.Have and enrich blood, invigorate blood circulation, the effect of collateral dredging.Can treat menoxenia, blood deficiency and yellow complexion, paralysis and numbness, rheumatic arthralgia etc.(the 151st page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
The Radix Rehmanniae nature and flavor are sweet, cold.GUIXIN, liver, kidney channel.Has clearing away heat and cooling blood, yin nourishing, the effect of promoting the production of body fluid.Can treat that calentura crimson tongue excessive thirst, interior-heat caused by deficiency of YIN, hectic fever due to YIN-deficiency consumptive fever, interior-heat are quenched one's thirst, haematemesis, epistaxis, send out speckle dermexanthesis etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 514th page).
Radix Angelicae Dahuricae nature and flavor suffering, temperature.Return stomach, large intestine, lung meridian.Has diffusing wind dehumidifying, understand things pain-stopping, the effect of detumescence and apocenosis.Can treat headache due to common cold, supraorbital bone pain, nasal obstruction, nasal sinusitis, toothache, leucorrhea, skin infection swells and ache etc.(the 79th page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
Radix Saposhnikoviae nature and flavor suffering, sweet, temperature.Return bladder, liver, spleen channel.Have inducing diaphoresis to dispel wind, win and wet, the effect of relieving convulsion.Can treat headache due to common cold, rheumatic arthralgia, rubella pruritus, tetanus etc.(the 117th page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
Rhizoma Chuanxiong property of medicine suffering, temperature.Return liver, gallbladder, pericardium channel.Has blood circulation promoting and blood stasis dispelling, activating QI to alleviate the depression, the effect of wind-expelling pain-stopping.Can treat menoxenia, the amenorrhea dysmenorrhea, the stagnant stomachache of the stasis of blood in puerperal ， mass in the abdomen lump, pain in chest and hypochondrium, it is dizzy to have a headache, anemofrigid-damp arthralgia, traumatic injury, ulcer sores etc.(the 292nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Angelicae Sinensis nature and flavor are sweet, hot, warm.Return liver, the heart, spleen channel.Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, the effect of loosening bowel to relieve constipation.Can be used for blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea stimulates the menstrual flow, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, traumatic injury, ulcer sores etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 553rd page).
The Lignum Sappan nature and flavor are sweet, salty, and are flat.GUIXIN, liver, spleen channel.Has the promoting the circulation of blood blood stasis dispelling, the effect of reducing swelling and alleviating pain.Can treat the amenorrhea dysmenorrhea, postpartum stagnation, breast ventral spine pain, wound swell and ache etc.(the 130th page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
Herba Spirodelae property of medicine suffering, cold.Return lung, urinary bladder channel.Has relieving the exterior syndrome by diaphoresis, inducing diuresis to remove edema, the effect of heat-clearing and toxic substances removing.Can treat the wind heat exterior syndrome, measles without adequate eruption, the urticaria pruritus, edema, the difficulty in urination, the skin ulcer tinea, erysipelas is scalded etc.(the 2765th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Fructus Tribuli nature and flavor suffering, hardship, tepor; Slightly poisonous.Return Liver Channel.Have the suppressing the hyperactive liver resolving depression, promoting blood circulation by removing wind makes eye bright, the itching relieving effect.It is dizzy to treat headache, distending pain in the chest and hypochondrium, and breast closes acute mastitis, conjunctival congestion cataracta, rubella pruritus etc.(the 289th page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Semen Astragali Complanati, Semen Cuscutae and Semen Sesami Nigrum; With Fructus Psoraleae, Caulis Spatholobi, Radix Rehmanniae, the Radix Angelicae Dahuricae, Radix Saposhnikoviae, Rhizoma Chuanxiong with when being classified as ministerial drug; With Lignum Sappan, Herba Spirodelae and Fructus Tribuli is adjuvant.All medicines are harmonious, tool nourishing the liver and kidney altogether, the skin moistening white effect that disappears.The treatment vitiligo has determined curative effect, has no side effect taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment vitiligo of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat vitiligo, and leukodermic prevention is also had good effect, and the treatment vitiligo has determined curative effect, has no side effect taking convenience, cheap characteristics.
For showing medicine of the present invention, as follows through clinical test results to treatment therapy for vitiligo effect; Treatment patients with vitiligo 57 examples, male's 33 examples, women's 24 examples, the age is 18～60 years old.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.One month is a course of treatment, take continuously three the course of treatment observe the curative effect.44 examples of fully recovering account for 77.19%, and 9 examples that take a turn for the better account for 15.79%, and more 4 examples do not account for 7%, and total effective rate reaches 93%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
The embodiment decoction takes by weighing raw material by following weight:
2 parts of 2 parts of Radixs Angelicae Dahuricae of 3 parts of Fructus Psoraleaes of Semen Astragali Complanati
2 parts of 2 parts of Radix Saposhnikoviaes of 3 portions of Caulis Spatholobis of Semen Sesami Nigrum
2 parts of 2 parts of Rhizoma Chuanxiongs of 3 parts of Radix Rehmanniae of Semen Cuscutae
1 part in 1 portion of Herba Spirodelae of 2 portions of Lignum Sappans of Radix Angelicae Sinensis
1 part of Fructus Tribuli
Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5～2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1～1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The leukodermic decoction of the treatment that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.One month is a course of treatment.
Claims (3)
1, the leukodermic Chinese medicine preparation of a kind of treatment is characterized in that it is made by the following weight proportion raw material:
1.0～4 parts of 1.0～4 parts of Radixs Angelicae Dahuricae of 1.5～6 parts of Fructus Psoraleaes of Semen Astragali Complanati
1.0～4 parts of 1.0～4 parts of Radix Saposhnikoviaes of 1.5～6 portions of Caulis Spatholobis of Semen Sesami Nigrum
1.0～4 parts of 1.0～4 parts of Rhizoma Chuanxiongs of 1.5～6 parts of Radix Rehmanniae of Semen Cuscutae
0.1～2 part in 0.1～2 portion of Herba Spirodelae of 1.0～4 portions of Lignum Sappans of Radix Angelicae Sinensis
0.1～2 part of Fructus Tribuli.
2, the leukodermic Chinese medicine preparation of a kind of treatment according to claim 1, wherein the weight proportion of each raw material is:
1.5～2.5 parts of 1.5～2.5 parts of Radixs Angelicae Dahuricae of 2.5～3.5 parts of Fructus Psoraleaes of Semen Astragali Complanati
1.5～2.5 parts of 1.5～2.5 parts of Radix Saposhnikoviaes of 2.5～3.5 portions of Caulis Spatholobis of Semen Sesami Nigrum
1.5～2.5 parts of 1.5～2.5 parts of Rhizoma Chuanxiongs of 2.5～3.5 parts of Radix Rehmanniae of Semen Cuscutae
0.5～1.5 part in 0.5～1.5 portion of Herba Spirodelae of 1.5～2.5 portions of Lignum Sappans of Radix Angelicae Sinensis
0.5～1.5 part of Fructus Tribuli.
3, the leukodermic Chinese medicine preparation of a kind of treatment according to claim 1, wherein the weight proportion of each raw material is:
2 parts of 2 parts of Radixs Angelicae Dahuricae of 3 parts of Fructus Psoraleaes of Semen Astragali Complanati
2 parts of 2 parts of Radix Saposhnikoviaes of 3 portions of Caulis Spatholobis of Semen Sesami Nigrum
2 parts of 2 parts of Rhizoma Chuanxiongs of 3 parts of Radix Rehmanniae of Semen Cuscutae
1 part in 1 portion of Herba Spirodelae of 2 portions of Lignum Sappans of Radix Angelicae Sinensis
1 part of Fructus Tribuli.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200710099194 CN101049370A (en) | 2007-05-16 | 2007-05-16 | Preparation of Chinese traditional medicine for treating leucoderma |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200710099194 CN101049370A (en) | 2007-05-16 | 2007-05-16 | Preparation of Chinese traditional medicine for treating leucoderma |
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| CN101049370A true CN101049370A (en) | 2007-10-10 |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103893705A (en) * | 2014-04-18 | 2014-07-02 | 山东省千佛山医院 | Traditional Chinese medicine for treating leucoderma by oral administration and washout |
| CN103989738A (en) * | 2014-05-18 | 2014-08-20 | 洛阳市安普生物科技有限公司 | Formula of antibacterial liquid for treating leucoderma and sweat white spot |
| CN105687407A (en) * | 2016-03-15 | 2016-06-22 | 鲁邦卫 | Traditional Chinese medicine composition for treating leucoderma |
-
2007
- 2007-05-16 CN CN 200710099194 patent/CN101049370A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103893705A (en) * | 2014-04-18 | 2014-07-02 | 山东省千佛山医院 | Traditional Chinese medicine for treating leucoderma by oral administration and washout |
| CN103989738A (en) * | 2014-05-18 | 2014-08-20 | 洛阳市安普生物科技有限公司 | Formula of antibacterial liquid for treating leucoderma and sweat white spot |
| CN105687407A (en) * | 2016-03-15 | 2016-06-22 | 鲁邦卫 | Traditional Chinese medicine composition for treating leucoderma |
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Open date: 20071010 |