CN103893705A - Traditional Chinese medicine for treating leucoderma by oral administration and washout - Google Patents
Traditional Chinese medicine for treating leucoderma by oral administration and washout Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine for treating leucoderma by oral administration and washout, and belongs to the technical field of a traditional Chinese medicine. The internal medicine is prepared from the following crude drugs: rehmannia glutinosa libosch, radix angelicae, fructus psoraleae, radix curcumae longae, rhizoma smilacis glabrae, radix bupleuri, rhizoma atractylodis, schizonepeta, glossy privet fruit, caulis spatholobi, prepared fleece flower root, root bark of the peony tree, fruit of Chinese wolfberry, angelica sinensis, herba epimedii, root of red-rooted salvia, uncaria, golden cypress, tuber fleeceflower stem, peach kernel, flowers carthami and liquorice. The washout medicine is prepared from the following raw materials: schizonepeta, almond, alum, mint, angelica sinensis, radix angelicae, radices sileris, fructus forsythia, rhizoma smilacis glabrae, polygonum multiflorum, root of common peony, radix sophorae flavescentis and borneol. The internal medicine disclosed by the invention has the effects of warming meridians, dredging qi and blood, clearing away heat and toxic materials, promoting blood circulation to remove blood stasis and the like. The external medicine can directly act on skin of the affected part and remove vitiligo, so as to roundly inhibit and effectively cure leucoderma. Thus, the target of complete recovery is achieved.
Description
Technical field
The present invention relates to one and treat leukodermic Chinese medicine, specifically one is treated leukodermic Chinese medicine by for oral administration, washout, belongs to technical field of Chinese medicines.
Background technology
Vitiligo is a kind of common posteriority limit office's property or general the de-disease of losing of property skin pigment, and this disease forms white macula as feature taking local or general property depigmentation, cause, but mechanism is not clear because the melanocyte function of skin disappears.Decolouring speckle differs in size from several millimeters to several centimetres, and in progressive stage, skin lesion can expand gradually, and constantly has new decolouring speckle to occur.Vitiligo is apt to occur in the positions such as face, neck, the back of the body, trunk and external genitalia, and especially the position such as head, face, neck, buttocks, the back of the hand is the most common.
Aspect treatment vitiligo, the Therapeutic Method of doctor trained in Western medicine is widely used always, the leukodermic method of western medical treatment mainly contains following several: pharmacotherapy: as Aeroseb-Dexs such as prednisones, this medicine is pretty good to vitiligo therapeutic effect, and take effect is also than faster, but this type of drug side effect is larger, long-time use can cause the complication such as obesity, hirsutism, blood sugar increasing, hypertension, menoxenia, osteoporosis, also can cause damage to kidney; Be instant effect by the leukodermic advantage of operative treatment, use this therapy need to ensure that patient is in vitiligo stable phase, improper use may cause colleague's reaction, causes the state of an illness further to increase the weight of; Ultraviolet therapy is to shine white macula position with long wave ultraviolet, to advance melanic generation.Although curing, this ultraviolet can advance melanic formation, if single unsatisfactory with the ultraviolet effect of shining.So existing therapy is all not ideal enough.
Summary of the invention
The object of the invention is to solve the problem that prior art exists, a kind of determined curative effect is provided, that what cure rate was high pass through is for oral administration, washout is treated leukodermic Chinese medicine.
Technical scheme of the present invention is:
One is treated leukodermic Chinese medicine by for oral administration, washout, it is characterized in that, comprises endo-medicine and external used medicine;
Described endo-medicine is made up of the raw material of following weight: 10 grams, the Radix Rehmanniae, 10 grams of the Radixs Angelicae Dahuricae, 10 grams of Fructus Psoraleaes, 10 grams, Rhizoma Curcumae Longae, 10 grams of Rhizoma Smilacis Glabraes, 10 grams of Radix Bupleuri, 10 grams of Rhizoma Atractylodis, 10 grams of Herba Schizonepetae, 10 grams of Fructus Ligustri Lucidi, 15 grams of Caulis Spatholobis, 15 grams of Radix Polygoni Multiflori Preparata, 15 grams of Cortex Moutans, 15 grams of Fructus Lycii, 15 grams of Radix Angelicae Sinensis, 15 grams of Herba Epimedii, 15 grams of Radix Salviae Miltiorrhizaes, Ramulus Uncariae Cum Uncis 15g, 25 grams of Cortex Phellodendris, 25 grams of Caulis Polygoni Multiflori, 6 grams, Semen Persicae, 6 grams, Flos Carthami, 3 grams, Radix Glycyrrhizae;
Described external used medicine is made up of the raw material of following weight: 10 grams of Herba Schizonepetae, 10 grams, Semen Armeniacae Amarum, 10 grams of Alumens, 10 grams of Herba Menthaes, 15 grams of Radix Angelicae Sinensis, 15 grams of the Radixs Angelicae Dahuricae, 15 grams of Radix Saposhnikoviaes, 20 grams of Fructus Forsythiaes, 20 grams of Rhizoma Smilacis Glabraes, 25 grams of Radix Polygoni Multiflori, 25 grams of Radix Paeoniae Rubra, 25 grams of Radix Sophorae Flavescentiss, Borneolum Syntheticum 6g.
By a preparation method for oral administration, that washout is treated leukodermic Chinese medicine, it is characterized in that, comprise the following steps:
The preparation method of endo-medicine:
1. take raw material according to above-mentioned weight,
2. endo-medicine raw material step being taken in is 1. placed in marmite, then adds water to and does not have raw material 2-5cm, soaks after 10-20min, is heated to 50 DEG C, adds a cover insulation 20-50min; Then big fire is heated to boiling, turns little fire and decocts 30-90min, filters, and obtains filtrate one, and filtering residue stays in pot, adds water to and does not have filtering residue, continues to decoct 10-20min, filters, and obtains filtrate two;
3. filtrate one and filtrate two are merged, mix, obtain endo-medicine;
The preparation method of external used medicine:
1) take raw material according to above-mentioned weight,
2) the external used medicine raw material except Borneolum Syntheticum taking in step 1) is bound up with gauze, put into marmite and decoct 20min, add Borneolum Syntheticum, after 5min, pull bundle out, dry, decoct liquid and be external used medicine.
The present invention also provides a kind of and it is characterized in that by using method for oral administration, that washout is treated leukodermic Chinese medicine,
Described Chinese medicine for oral administration potion every day, every dose twice;
Described external used medicine, takes fumigation and wash method 15-20min after Chinese medicine for oral administration every day for the second time, after fumigation and wash method, bundle is spread on to affected part 1-2h.
Above-mentioned two kinds of medicines are potion every day, wash every day twice.It within 30 days, is a course for the treatment of.
The pharmacological action of each Chinese medicine:
The Radix Rehmanniae: clearing up internal heat by using drugs of bitter in taste and cold in nature, Gan Hanzhi moistens yin nourishing, for the refrigerant product that moisten, is good at nourishing YIN and clearing away heat removing heat from blood.Effect clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting, intestine moistening.
The Radix Angelicae Dahuricae: pungent, temperature.Enter lung, thigh, stomach warp.Dispel the wind, dampness, detumescence, pain relieving.Control headache, supraorbital bone pain, toothache, nasal sinusitis, cold-damp stomachache, hemorrhoidal hamorrhage anal fistula, leucorrhea with red and white discharge, ulcer sores, skin pruritus due to dryness, scabies.
Fructus Psoraleae: reinforcing the kidney and supporting YANG.Control the cold diarrhea of suffering from a deficiency of the kidney, the enuresis, spermatorrhea, frequent micturition, sexual impotence, chills and pain of the waist and kness, deficiency and coldness is breathed heavily and is coughed.
Rhizoma Curcumae Longae: removing blood stasis, circulation of qi promoting, stimulates the menstrual flow, pain relieving.Control trusted subordinate's feeling of fullness distending pain, brachialgia ， mass in the abdomen, women's blood stasis amenorrhea, puerperal, the stasis of blood was stopped stomachache, injury from falling down, carbuncle.
Rhizoma Smilacis Glabrae: sweet, light, flat.Return liver, stomach warp.Dehumidifying, removing toxic substances, easing joint movement.For damp and hot stranguria with turbid discharge, leukorrhagia, carbuncle, scrofula, scabies, the limbs contracture due to syphilis and mercurialism, bones and muscles pain.
Radix Bupleuri: pungent, micro-hardship, be slightly cold; Return liver, gallbladder meridian.Induce sweat and bring down a fever, soothing liver-QI for relieving depression, elevate a turnable ladder yang-energy.This product is dredged to reach and kind be thoroughly longer than and discongest stagnant heat in the liver and gall, again can depressed liver-energy dispersing and QI regulating, and be pain over the hypochondriac region key medicine due to treatment stagnant heat in the liver and gall, stagnation of QI due to depression of the liver.
Rhizoma Atractylodis: arduous, temperature.Enter spleen, stomach warp.Spleen invigorating, dampness, resolving depression, wards off dirty.Control the wet tired spleen of containing, asthenia drowsiness, gastral cavity painful abdominal mass abdominal distention, inappetence, vomiting, has loose bowels, dysentery, malaria, phlegm retention, edema, seasonal epidemic pathogens flu, anemofrigid-damp arthralgia, flaccidity of the lower limbs, nyctalopia.
Herba Schizonepetae: pungent, temperature.Enter lung, Liver Channel.Deliver, dispel the wind, treating blood disorders; Parch to black hemostasis.The heating that cures cold, headache, laryngopharynx swelling and pain, apoplexy locked mouth, spits blood, and epistaxis, has blood in stool; Metrorrhagia, puerperal blood faints; Carbuncle, skin ulcer scabies, scrofula.
Fructus Ligustri Lucidi: bitter sweet, flat.Enter liver, kidney channel.Invigorating the liver and kidney, strong waist knee joint.Control yin asthenia generating intrinsic heat, dizziness, order flower, tinnitus, soreness of the waist and knees, early whitening of beard and hair.Nourishing the liver and kidney, improving eyesight black hair.For vertigo and tinnitus, soreness of the waist and knees, early whitening of beard and hair, poor vision.
Caulis Spatholobi: bitter, micro-sweet, temperature; Return Liver Channel.Enrich blood and invigorate blood circulation, dredge the meridian passage.This product abnormal smells from the patient is soft, walks to keep and has both, and can change cloudy hemopoietic, promoting the flow of QI-blood by warming the meridian, and promoting blood circulation to remove obstruction in the collateral, pushes away Chen Zhixin, embellishes but not dry, tonify without causing stagnation, row and mend broken feature, to the rheumatic arthralgia due to blood deficiency, all cards of stasis pain and gynecological, all have good effect.
Radix Polygoni Multiflori Preparata: bitter sweet puckery, tepor.Enter liver, kidney channel.Invigorating the liver and kidney, benefiting essence-blood, black beard and hair, strengthening bone and muscle; For vertigo and tinnitus, early whitening of beard and hair, soreness of the waist and knees, numb limbs and tense tendons, neurasthenia, hyperlipidemia.
Cortex Moutan: heat clearing away, removing heat from blood, and blood, repercussive.Control the pathogenic heat attacking blood system in febrile diseases, send out speckle, infantile convulsion, tells, is defeated in battle, has blood in stool, hectic fever due to YIN-deficiency consumptive fever, and amenorrhea ， mass in the abdomen, carbuncle and ulcer, flutters damage.
Fructus Lycii: sweet, flat.Enter liver, kidney channel.Nourishing kidney, lung moistening, tonifying liver, improving eyesight.Control hepatic and renal YIN deficiency, soreness of the waist and knees, dizziness, dizzy, the many tear of blurred vision, cough due to consumptive disease, quenches one's thirst, seminal emission.
Radix Angelicae Sinensis: sweet, acrid, warm.Enter the heart, liver, spleen channel.Benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturizes laxation.Control menoxenia, amenorrhea stomachache ， mass in the abdomen knot is poly-, metrorrhagia; Headache due to deficiency of blood, dizzy, flaccidity syndrome and arthralgia syndrome; Dryness of the intestine dyschezia is heavy after bloody dysentery; Carbuncle skin ulcer is stolen, injury from falling down.
Herba Epimedii: Xin Gan, temperature.Enter liver, kidney channel.Kidney invigorating and YANG supporting, expelling wind and removing dampness.Control sexual impotence erectile problem, dribbling urination, muscles and bones contraction is anxious, hemiplegia, weakness of the waist and knees, rheumatic arthralgia, extremity are meciless.
Radix Salviae Miltiorrhizae: hardship, is slightly cold; GUIXIN, Liver Channel.Activating blood circulation to dissipate blood stasis, removing heat from blood mind calming.This product is fallen and promoting the circulation of blood, is apt to into blood system, can qualcomm meridian, change stasis, clearing away heart-fire, removing heat from blood heat, and the will of calming the nerves, tired except throbbing with fear, is usually used in obstruction of qi in the chest and cardialgia, and menstruation portion adjusts, skin infection swells and ache, insomnia and the congestion disease such as swell and ache.
Ramulus Uncariae Cum Uncis: sweet, cool.Enter liver, heart channel.Heat clearing away suppressing the hyperactive liver, arresting convulsion relieves dizziness, high fever, infantile convulsions, epilepsy, etc.Control pediatric epilepsy scared Chi Zong, adult's blood pressure is higher, dizzy, dizzy, married woman's eclamposia.
Cortex Phellodendri: hardship, cold.Enter kidney, urinary bladder channel.Heat clearing away, dampness, pathogenic fire purging is except steaming, detoxification sore treatment.For damp-heat dysentery, jaundice, leukorrhagia, pyretic stranguria, osteopyrexia and fever, night sweat, seminal emission, sore swollen toxin, eczema pruritus.
Caulis Polygoni Multiflori: sweet, micro-hardship, flat; GUIXIN, Liver Channel.This product property of medicine is gentle, and energy wind-damp dispelling, the network of passing through, qualcomm meridian, eliminating heart-fire, tranquilizing mind, be usually used in the disease such as pyretic arthralgia and vexed insomnia.
Semen Persicae: bitter sweet, flat.Enter the heart, liver, large intestine channel.Blood stasis removing and clots absorbing, moisturizes laxation.Control amenorrhea ， mass in the abdomen, calentura blood-retention, migratory arthralgia, malaria, traumatic injury, swelling and pain due to blood stasis, the dry constipation of blood.
Flos Carthami: pungent, temperature.Enter the heart, Liver Channel.Promoting blood circulation to restore menstrual flow, blood stasis removing pain relieving.Control amenorrhea ， mass in the abdomen, difficult labour, stillborn fetus, disease that postpartum lochia can't go, blood stasis are had a pain, carbuncle, injury from falling down.
Radix Glycyrrhizae: sweet, flat.GUIXIN, lung, spleen, stomach warp.Invigorating the spleen and replenishing QI, grows and coughs lung moistening, emergency removing toxic substances, mediation hundred medicines.
Herba Schizonepetae: pungent, temperature.Enter lung, Liver Channel.Deliver, dispel the wind, treating blood disorders; Parch to black hemostasis.The heating that cures cold, headache, laryngopharynx swelling and pain, apoplexy locked mouth, spits blood, and epistaxis, has blood in stool; Metrorrhagia, puerperal blood faints; Carbuncle, skin ulcer scabies, scrofula.
Semen Armeniacae Amarum: expelling phlegm for arresting cough, relieving asthma, intestine moistening.Control exogenous cough, dyspnea with fullness of the chest, sore throat, dryness of the intestine constipation.
Alumen: sour and astringent, cold.Poisonous.Enter lung, spleen, stomach, large intestine channel.Expectorant, dampness, antidiarrheal, hemostasis, removing toxic substances, parasite killing.Control epilepsy, sore throat, remorse saliva is stopped up very, hepatitis, jaundice, general edema with yellowish skin, Stomach duodenum ulcer, uterine prolapse, leucorrhea, dysentery, epistaxis, aphtha of the mouth and tongue, skin ulcer hemorrhoid scabies, water, fire, insect bite.
Herba Menthae: pungent, cool.Enter lung, Liver Channel.Dispelling wind, heat radiation, ward off dirty, removing toxic substances.Control affection due to external wind and heat, headache, conjunctival congestion, laryngopharynx swelling and pain, dyspepsia flatulence, aphtha, toothache, skin ulcer scabies, urticaria.
Radix Angelicae Sinensis: sweet, acrid, warm.Enter the heart, liver, spleen channel.Benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturizes laxation.Control menoxenia, amenorrhea stomachache ， mass in the abdomen knot is poly-, metrorrhagia; Headache due to deficiency of blood, dizzy, flaccidity syndrome and arthralgia syndrome; Dryness of the intestine dyschezia is heavy after bloody dysentery; Carbuncle skin ulcer is stolen, injury from falling down.
The Radix Angelicae Dahuricae: pungent, temperature.Enter lung, thigh, stomach warp.Dispel the wind, dampness, detumescence, pain relieving.Control headache, supraorbital bone pain, toothache, nasal sinusitis, cold-damp stomachache, hemorrhoidal hamorrhage anal fistula, leucorrhea with red and white discharge, ulcer sores, skin pruritus due to dryness, scabies.
Radix Saposhnikoviae: Xin Gan, temperature.Enter bladder, lung, spleen channel.Deliver and dispel the wind, victory is wet, pain relieving. control affection of exogenous wind-cold, and headache, dizzy, stiffness of the nape, anemofrigid-damp arthralgia, joint is ached.
Fructus Forsythiae: heat clearing away, removing toxic substances, eliminating stagnation, detumescence.Control warm, erysipelas, macule, carbuncle and ulcer toxic swelling, scrofula, urine stranguria with urinary obstruction; Laryngopharynx swelling and pain, rubella.
Rhizoma Smilacis Glabrae: sweet, light, flat.Return liver, stomach warp.Dehumidifying, removing toxic substances, easing joint movement.For damp and hot stranguria with turbid discharge, leukorrhagia, carbuncle, scrofula, scabies, the limbs contracture due to syphilis and mercurialism, bones and muscles pain.
Radix Polygoni Multiflori: bitter sweet puckery, tepor.Enter liver, kidney channel.Tonifying liver, kidney tonifying, nourishes blood, and dispels the wind.Control hepatic and renal YIN deficiency, sending out must be early white, blood deficiency dizziness, and waist knee joint weakness, muscles and bones is ached, seminal emission, metrorrhagia and leukorrhagia, chronic malaria, chronic dysentery, chronic hepatitis, carbuncle, scrofula, hemorrhoidal hamorrhage, haemorrhoids.
Radix Paeoniae Rubra: hardship, is slightly cold.Return Liver Channel.Clearing away heat and cooling blood, eliminating stasis to stop pain.For maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea ， mass in the abdomen stomachache, injury from falling down, carbuncle skin infection.
Radix Sophorae Flavescentis: hardship, cold.Enter liver, kidney, large intestine, small intestine meridian.Heat clearing away, dampness, parasite killing.Control toxic-heat and blood stasis, discharging fresh blood stool, jaundice, leucorrhea with red and white discharge, infantile pneumonia, infantile malnutrition, acute tonsillitis, anal fistula, proctoptosis, skin pruritus, mange malignant boil, erosion of vulva pruritus due to damp pathogen, scrofula, scalds.External heat-clearing and toxic substances removing, dampness removing to stop itchin.
Borneolum Syntheticum: arduous, cool.Enter the heart, lung meridian.Logical all keys, loose stagnated fire, removing nebula improving eyesight, reducing swelling and alleviating pain.Control apoplexy locked mouth, calentura coma, infantile convulsion expectorant fan, deafness with qi stagnation, sore throat, aphtha, otitis media, carbuncle, hemorrhoid, order is nebula film also, enterobiasis.
Chinese medicine thinks that vitiligo pathogeny is that in body, ailment said due to cold or exposure is flourishing, and that sends out gives birth in table.We are for the pathology and disease mechanism of vitiligo and reasonable formula, meticulous compatibility, medicine with Radix Salviae Miltiorrhizae, the Radix Angelicae Dahuricae, Rhizoma Curcumae Longae, Herba Epimedii, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae, Caulis Spatholobi, Semen Persicae, Flos Carthami dispelling wind and removing obstruction in the collateral, promoting flow of QI and blood is removed the exopathogen that causes a disease, get through the stasis of blood stagnant, impel QI-blood circulation unobstructed; The Radix Rehmanniae, Fructus Psoraleae, Radix Polygoni Multiflori Preparata, Caulis Polygoni Multiflori, Rhizoma Atractylodis, Herba Schizonepetae, Cortex Moutan, dispelling wind to relieve the exterior syndrome, clearing away heat and cooling blood, cuts off pathogenesis; Again with Rhizoma Smilacis Glabrae, Radix Bupleuri, Fructus Ligustri Lucidi, Fructus Lycii, Ramulus Uncariae Cum Uncis, Cortex Phellodendri removing dampness and detoxicating, the liver and the kidney tonifying; Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription, all medicine compatibilities, strengthen resisting the exopathogen that causes a disease.The fumigation and wash method to skin lesion position by medicine simultaneously, utilize skin to there is absorption, the characteristic of infiltration, Excretion, the thermogenetic effect producing when stifling, blood and the lymph circulation of promotion parts of body, strengthen metabolism, improve body's immunity, there is the effects such as temperature three-way meridian, fluent QI and blood, heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, thereby suppress comprehensively and effectively cure vitiligo, to reach the object of thorough rehabilitation.
Beneficial effect of the present invention: the present invention is by after said medicine combination, and its drug effect has synergism, has effect of temperature three-way meridian, fluent QI and blood, heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, and treatment vitiligo is evident in efficacy.Compositions of the present invention has no side effect, and preparation is simple, and medicine source is wide, cost is low, easy to use.This medicament is carried out to clinical practice, evident in efficacy, there is not toxic and side effects, total effective rate can reach 96%.
Below in conjunction with clinical data and model case, beneficial effect of the present invention is further illustrated.
One, clinical observation
1, clinical data: selected 50 routine patients with vitiligo altogether, clinical leukodermic diagnostic criteria, the stadium 1 month～15 years of meeting.Carry out stratified random by the state of an illness, by study subject random assortment to treatment group (Chinese drug-treated group) and matched group (Western medicine group).Treatment group 25 examples, 12～68 years old age, average 32.8 years old; The course of disease 2 months～15 years; Matched group 25 examples, 10～72 years old age, average 34.1 years old; The course of disease 1 month～18 years.Two groups of patient ages, the course of disease, state of an illness comparing difference not statistically significant (P > O.05), two groups have comparability.
2, diagnostic criteria:
1) the morbidity day after tomorrow, agnogenic depigmentation speckle.White macula is often creamy white, and size, form differ, and on it, hair can normally or bleach.
2) feature distributing according to erythra is divided into homeliness type (topical type, general hair style, distribute type, acra type) and segmental pattern.Homeliness type skin lesion is generally symmetrical, can be confined to some position or distribute, general whole body.Segmental pattern is generally one-sided, and white macula distributes along a certain tegumentary nerve joint domination district.
3) course of disease is slow, without obvious subjective symptoms.
3, Therapeutic Method:
(1), treatment group: take Chinese medicine for oral administration of the present invention, be decocted in water for oral dose, every day, potion, took for every dose at twice, respectively early after meal with late one after each meal; It within 30 days, is a course for the treatment of;
External used medicine (locating Borneolum Syntheticum outer) is bound up with gauze, put into marmite decocting and boil after 20 minutes, add 6 grams of Borneolum Syntheticums, after 5 minutes, pull bundle out, fumigation and wash method affected part 15～20 minutes (take evening endo-medicine after fumigation and wash method), every day potion, washing every day twice, 30 day is a course for the treatment of.
(2), matched group: dexamethasone for oral administration, fursultiamine sheet; External tacrolimus ointment, 0.1% for adult, 0.03% for≤12 years old child, every day coating 2 times, 2 minor tick time >=8h.
Within every 2～4 weeks, follow up a case by regular visits to 1 time, and take the photograph photo, with relatively, observe the state of an illness, record effect and possible untoward reaction, observing 3 months is 1 course for the treatment of.
4, efficacy assessment standard:
(1) recovery from illness: white macula all disappears;
(2) effective: white macula dwindles, disappears >=and 50%;
(3) effective: white macula dwindles, disappears
(4) invalid: symptom is all without taking a turn for the better.
5, therapeutic outcome
In table 1.
Table 1 therapeutic outcome data
| Group | n | Clinical recovery | Effective | Effectively | Invalid | Total effective rate (%) |
| Treatment group | 25 | 14 | 8 | 2 | 1 | 96 |
| Matched group | 25 | 5 | 7 | 4 | 9 | 64 |
Result: show by upper table treatment situation, treatment group total effective rate is 96%, and matched group total effective rate is 64%, and treatment group curative effect is better than matched group.
Two, model case
Case 1, Liu, female, 57 years old, retired worker.Before patient half a year there are two place's white maculas in skin of chest abdomen, is diagnosed as vitiligo at local hospital, invalid by many hospitalizes, and white macula constantly expands and increases.Started afterwards to adopt formula of the present invention, and by Chinese medicine for oral administration, coordinated external used medicine fumigation and wash method simultaneously, after 3 months, her white macula has disappeared 2/3, and after half a year, white macula all disappears.After treatment drug withdrawal in 3 months again.Follow up a case by regular visits to so far, have no recurrence.
Case 2, Zhang, man, 23 years old, university students.Before Xiao Zhang half a year, discovery has a skin whiter than other positions on the face, but does not take notice of.Inadvertently, the white macula that Semen phaseoli radiati is large grows up to coin-size.Be diagnosed as vitiligo at local hospital afterwards, after adopting two courses for the treatment of of Drug therapy of the present invention, there is obviously casting off a skin ruddy phenomenon in white macula.After two courses for the treatment of of continual cure, white macula thoroughly disappears, and follows up a case by regular visits to so far not recurrence.
Case 3, king so-and-so, man, 35 years old, General Office Clerk.Xiao Wang finds that the year before the corners of the mouth has a white macula, does not take notice of at that time, and white macula started to expand afterwards, went to hospital to be diagnosed as vitiligo.He has adopted doctor's suggestion, adopt our treatment by Chinese herbs, improve internal organs environment by oral medicine, Yin Yang balancing vim and vigour, dredging the meridian, balance immunity, external used medicine fumigation and wash method in addition, repair skin lesion, reach melanocyte regeneration thereby act on sick body by inside and outside two kinds of means simultaneously, skin is become again former.So far more than half a year, do not recur.
Detailed description of the invention
Embodiment 1:
One is treated leukodermic Chinese medicine by for oral administration, washout, comprises endo-medicine and external used medicine;
Endo-medicine: 10 grams, the Radix Rehmanniae, 10 grams of the Radixs Angelicae Dahuricae, 10 grams of Fructus Psoraleaes, 10 grams, Rhizoma Curcumae Longae, 10 grams of Rhizoma Smilacis Glabraes, 10 grams of Radix Bupleuri, 10 grams of Rhizoma Atractylodis, 10 grams of Herba Schizonepetae, 10 grams of Fructus Ligustri Lucidi, 15 grams of Caulis Spatholobis, 15 grams of Radix Polygoni Multiflori Preparata, 15 grams of Cortex Moutans, 15 grams of Fructus Lycii, 15 grams of Radix Angelicae Sinensis, 15 grams of Herba Epimedii, 15 grams of Radix Salviae Miltiorrhizaes, Ramulus Uncariae Cum Uncis 15g, 25 grams of Cortex Phellodendris, 25 grams of Caulis Polygoni Multiflori, 6 grams, Semen Persicae, 6 grams, Flos Carthami, 3 grams, Radix Glycyrrhizae;
External used medicine: 10 grams of Herba Schizonepetae, 10 grams, Semen Armeniacae Amarum, 10 grams of Alumens, 10 grams of Herba Menthaes, 15 grams of Radix Angelicae Sinensis, 15 grams of the Radixs Angelicae Dahuricae, 15 grams of Radix Saposhnikoviaes, 20 grams of Fructus Forsythiaes, 20 grams of Rhizoma Smilacis Glabraes, 25 grams of Radix Polygoni Multiflori, 25 grams of Radix Paeoniae Rubra, 25 grams of Radix Sophorae Flavescentiss, Borneolum Syntheticum 6g.
The preparation method of endo-medicine:
1. take raw material according to above-mentioned weight,
2. endo-medicine raw material step being taken in is 1. placed in marmite, then adds water to and does not have raw material 2-5cm, soaks after 10-20min, is heated to 50 DEG C, adds a cover insulation 20-50min; Then big fire is heated to boiling, turns little fire and decocts 30-90min, filters, and obtains filtrate one, and filtering residue stays in pot, adds water to and does not have filtering residue, continues to decoct 10-20min, filters, and obtains filtrate two;
3. filtrate one and filtrate two are merged, mix, obtain endo-medicine;
The preparation method of external used medicine:
1) take raw material according to above-mentioned weight,
2) the external used medicine raw material except Borneolum Syntheticum taking in step 1) is bound up with gauze, put into marmite and decoct 20min, add Borneolum Syntheticum, after 5min, pull bundle out, dry, decoct liquid and be external used medicine.
Using method: described Chinese medicine for oral administration potion every day, every dose twice;
Described external used medicine, takes fumigation and wash method 15-20min after Chinese medicine for oral administration every day for the second time, after fumigation and wash method, bundle is spread on to affected part 1-2h.
Above-mentioned two kinds of medicines are potion every day, wash every day twice.It within 30 days, is a course for the treatment of.
Claims (3)
1. treat a leukodermic Chinese medicine by for oral administration, washout, it is characterized in that, comprise endo-medicine and external used medicine;
Described endo-medicine is made up of the raw material of following weight: 10 grams, the Radix Rehmanniae, 10 grams of the Radixs Angelicae Dahuricae, 10 grams of Fructus Psoraleaes, 10 grams, Rhizoma Curcumae Longae, 10 grams of Rhizoma Smilacis Glabraes, 10 grams of Radix Bupleuri, 10 grams of Rhizoma Atractylodis, 10 grams of Herba Schizonepetae, 10 grams of Fructus Ligustri Lucidi, 15 grams of Caulis Spatholobis, 15 grams of Radix Polygoni Multiflori Preparata, 15 grams of Cortex Moutans, 15 grams of Fructus Lycii, 15 grams of Radix Angelicae Sinensis, 15 grams of Herba Epimedii, 15 grams of Radix Salviae Miltiorrhizaes, Ramulus Uncariae Cum Uncis 15g, 25 grams of Cortex Phellodendris, 25 grams of Caulis Polygoni Multiflori, 6 grams, Semen Persicae, 6 grams, Flos Carthami, 3 grams, Radix Glycyrrhizae;
Described external used medicine is made up of the raw material of following weight: 10 grams of Herba Schizonepetae, 10 grams, Semen Armeniacae Amarum, 10 grams of Alumens, 10 grams of Herba Menthaes, 15 grams of Radix Angelicae Sinensis, 15 grams of the Radixs Angelicae Dahuricae, 15 grams of Radix Saposhnikoviaes, 20 grams of Fructus Forsythiaes, 20 grams of Rhizoma Smilacis Glabraes, 25 grams of Radix Polygoni Multiflori, 25 grams of Radix Paeoniae Rubra, 25 grams of Radix Sophorae Flavescentiss, Borneolum Syntheticum 6g.
2. according to claim 1ly it is characterized in that by preparation method for oral administration, that washout is treated leukodermic Chinese medicine, comprise the following steps:
The preparation method of endo-medicine:
1. weight according to claim 1 takes raw material,
2. endo-medicine raw material step being taken in is 1. placed in marmite, then adds water to and does not have raw material 2-5cm, soaks after 10-20min, is heated to 50 DEG C, adds a cover insulation 20-50min; Then big fire is heated to boiling, turns little fire and decocts 30-90min, filters, and obtains filtrate one, and filtering residue stays in pot, adds water to and does not have filtering residue, continues to decoct 10-20min, filters, and obtains filtrate two;
3. filtrate one and filtrate two are merged, mix, obtain endo-medicine;
The preparation method of external used medicine:
1) weight according to claim 1 takes raw material,
2) the external used medicine raw material except Borneolum Syntheticum taking in step 1) is bound up with gauze, put into marmite and decoct 20min, add Borneolum Syntheticum, after 5min, pull bundle out, dry, decoct liquid and be external used medicine.
According to claim 1 or prepare according to the method for claim 2 pass through using method for oral administration, that washout is treated leukodermic Chinese medicine, it is characterized in that,
Described Chinese medicine for oral administration potion every day, every dose twice;
Described external used medicine, takes after Chinese medicine for oral administration every day for the second time, uses external used medicine fumigation and wash method 15-20min, after fumigation and wash method, bundle is spread on to affected part 1-2h.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104491346A (en) * | 2014-12-16 | 2015-04-08 | 黄向业 | Traditional Chinese medicine for treating hyperostosis in oral administration and external application |
| CN104840784A (en) * | 2015-04-24 | 2015-08-19 | 孙玉 | Vitiligo eliminating ointment |
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| CN1174071A (en) * | 1997-07-12 | 1998-02-25 | 迟经惠 | Ointment for purpura nervosa and leukoderma |
| CN101049370A (en) * | 2007-05-16 | 2007-10-10 | 北京艺信堂医药研究所 | Preparation of Chinese traditional medicine for treating leucoderma |
| CN102038904A (en) * | 2009-10-15 | 2011-05-04 | 张红旗 | Chinese prescription for treating leucoderma |
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- 2014-04-18 CN CN201410157535.XA patent/CN103893705A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1174071A (en) * | 1997-07-12 | 1998-02-25 | 迟经惠 | Ointment for purpura nervosa and leukoderma |
| CN101049370A (en) * | 2007-05-16 | 2007-10-10 | 北京艺信堂医药研究所 | Preparation of Chinese traditional medicine for treating leucoderma |
| CN102038904A (en) * | 2009-10-15 | 2011-05-04 | 张红旗 | Chinese prescription for treating leucoderma |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104491346A (en) * | 2014-12-16 | 2015-04-08 | 黄向业 | Traditional Chinese medicine for treating hyperostosis in oral administration and external application |
| CN104840784A (en) * | 2015-04-24 | 2015-08-19 | 孙玉 | Vitiligo eliminating ointment |
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