CN101053650A - Traditional Chinese medicine preparation for curing seborrheic baldness - Google Patents

Abstract

The invention relates to a Chinese medicinal preparation for treating alopecia seborrheica comprising dozens of Chinese herbs including dried rehamnnia root, anemarrhena, glossy privet fruit and fleece-flower root. It can clear away heat and purge fire, nourish blood to regenerate hair. The invention is prepared by latest modern medical study result and is based on traditional syndrome differentiation on TCM. It has confirmed efficacy and low price, being safe, besides no side or toxic effect will be caused.

Description

A kind of Chinese medicine preparation for the treatment of seborrheic alopecia

Technical field

The present invention relates to a kind of Chinese medicine preparation for the treatment of seborrheic alopecia, is that a kind of seborrheic alopecia for the treatment of is the Chinese medicine preparation of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.

Background technology

Seborrheic alopecia claims male pattern alopecia, androgen alopecia, dispersivity alopecia again, is the alopecia that neck after the adolescence, temporo, top are made slow progress, and men and women's both sexes all can take place, but more common with the male patient.Clinical patient often goes out more, symptoms such as the dandruff is many, hair is withered, pruritus with seborrhea capitis.Primary disease pathogeny complexity, modern medicine is not illustrated as yet fully to this, think the autosome alopecia that a kind of androgen relies at present, androgen (testosterone, particularly free active testosterone), the androgen receptor of Follicular Unit, the activity of enzyme, alopecia district scalp (target organ) of genetic predisposition play an important role in the seborrheic alopecia disease.Primary disease belongs to categories such as Chinese medicine " alopecia seborrhoeica ", " alopecia seborrheica ".

The traditional Chinese medical science is divided into blood heat wind-dryness type, damp and hot fumigation type, deficiency of the liver and kindey type Coryza Treated by Syndrome Differentiation clinically and obtains better therapeutic effect.Primary disease hinders appearance, along with the raising of living standards of the people, the treatment of primary disease is come into one's own day by day.At present doctor trained in Western medicine is many can only be at etiological treatment, and recurrence easily, brings mentally and economically burden to the patient.

Summary of the invention

The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine preparation for the treatment of seborrheic alopecia.Have determined curative effect, safe ready, have no side effect, cheap characteristics.

The present invention is made by the following weight proportion raw material:

1.5～6 parts of 1.5～6 parts of Fructus Ligustri Lucidi of 1.5～6 parts of Rhizoma Anemarrhenaes of Radix Rehmanniae

1.0～4 parts of 1.0～4 parts of Rhizoma Smilacis Glabraes of 1.0～4 parts of Radix Salviae Miltiorrhizaes of Radix Polygoni Multiflori

1.0～4 parts in 1.0～4 parts of Poria of 1.0～4 portions of Rhizoma Alismatis of Radix Bupleuri

0.1～2 part of 0.1～2 part of Cortex Dictamni of 0.1～2 part of Rhizoma Curcumae of Fructus Corni

The weight proportion of each raw material of optimization formula of the present invention is:

2.5～3.5 parts of 2.5～3.5 parts of Fructus Ligustri Lucidi of 2.5～3.5 parts of Rhizoma Anemarrhenaes of Radix Rehmanniae

1.5～2.5 parts of 1.5～2.5 parts of Rhizoma Smilacis Glabraes of 1.5～2.5 parts of Radix Salviae Miltiorrhizaes of Radix Polygoni Multiflori

1.5～2.5 parts in 1.5～2.5 parts of Poria of 1.5～2.5 portions of Rhizoma Alismatis of Radix Bupleuri

0.5～1.5 part of 0.5～1.5 part of Cortex Dictamni of 0.5～1.5 part of Rhizoma Curcumae of Fructus Corni

The weight proportion of each raw material of optimum formula of the present invention is:

3 parts of 3 parts of Fructus Ligustri Lucidi of 3 parts of Rhizoma Anemarrhenaes of Radix Rehmanniae

2 parts of 2 parts of Rhizoma Smilacis Glabraes of 2 parts of Radix Salviae Miltiorrhizaes of Radix Polygoni Multiflori

2 parts in 2 parts of Poria of 2 portions of Rhizoma Alismatis of Radix Bupleuri

1 part of 1 part of Cortex Dictamni of 1 part of Rhizoma Curcumae of Fructus Corni

Drug action mechanism among the present invention is as follows:

The Radix Rehmanniae nature and flavor are sweet, cold.GUIXIN, liver, kidney channel.Has clearing away heat and cooling blood, yin nourishing, the effect of promoting the production of body fluid.Can treat that calentura crimson tongue excessive thirst, interior-heat caused by deficiency of YIN, hectic fever due to YIN-deficiency consumptive fever, interior-heat are quenched one's thirst, haematemesis, epistaxis, send out speckle dermexanthesis etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 514th page).

Rhizoma Anemarrhenae nature and flavor hardship, sweet, cold.Return lung, stomach, kidney channel.Has clearing away heat-fire, the effect of promoting the production of body fluid and moisturizing.Can treat that fever caused by exogenous pathogenic factors, hyperpyrexia excessive thirst, tuberculosis heating, cough due to lung-heat, osteopyrexia and fever, interior-heat are quenched one's thirst, the dryness of the intestine constipation, dysuria, diabetes etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 817th page).

The Fructus Ligustri Lucidi property of medicine is sweet, bitter, cold.Return liver, kidney channel.Has liver and kidney tonifying, clearind deficient heat, the effect that makes eye bright.Can treat Light-headedness, soreness of the waist and knees, seminal emission, tinnitus, early whitening of beard and hair, osteopyrexia and fever, poor vision etc.(the 324th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Radix Polygoni Multiflori nature and flavor hardship, sweet, puckery, temperature.Return liver, the heart, kidney channel.Has invigorating the liver and kidney, benefiting essence-blood, black beard and hair, the effect of bone and muscle strengthening.Can treat blood deficiency and yellow complexion, vertigo and tinnitus, early whitening of beard and hair, soreness of the waist and knees, numb limbs and tense tendons, bleeding not during menses, chronic malaria body void; Hyperlipidemia etc.(the 140th page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).

Radix Salviae Miltiorrhizae nature and flavor hardship is slightly cold.GUIXIN, Liver Channel.Has stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, the effect of the relieving restlessness that clears away heart-fire.Can treat menoxenia, amenorrhea dysmenorrhea ， lumps in the chest and abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia; Hepatosplenomegaly, angina pectoris etc.(the 57th page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).

The Rhizoma Smilacis Glabrae nature and flavor are sweet, light, flat.Return liver, stomach warp.Has heat-clearing and toxic substances removing, wind-damp dispelling, bone and muscle strengthening, sharp joint, anticancer effect.Can treat damp and hot sore, eczema, rheumatic ostalgia, limbs contracture, Fructus Myricae rubrae malignant boil, urinary system infection, syphilis, stranguria with turbid discharge, stranguria leucorrhea, dyspepsia, diarrhoea, beriberi, furuncle, carbuncle, scrofula etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 87th page).

Radix Bupleuri nature and flavor hardship, be slightly cold.Return liver, gallbladder meridian.Effect with reconciling superficies and interior, soothing the liver, yang invigorating.Can treat alternate attack of chill and fever, fullness in the chest and hypochondriac pain, deafness, headache and dizziness, malaria, dysentery proctoptosis, menoxenia, uterine prolapse, flu, upper respiratory tract infection, hepatitis, cholecystitis etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 1004th page).

The Rhizoma Alismatis nature and flavor are sweet, cold.Return kidney, urinary bladder channel.Has diuresis, the effect of clearing away damp-heat.Can treat dysuria, edema distension, the oliguria of having loose bowels, dizziness due to fluid-retention, the puckery pain of pyretic stranguria; Hyperlipidemia etc.(the 184th page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).

The Poria nature and flavor are sweet, flat, light.GUIXIN, lung, spleen, kidney channel.Has eliminating dampness and diuresis, the effect of strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming.Can treat that dysuria, edema distension, phlegm retention cough with dyspnea, brain are throbbed with fear, have loose bowels in the loose stool, irritability, palpitation with fear, insomnia, forgetful, seminal emission, stranguria with turbid discharge, insufficiency of the spleen, stop that drink is not eaten, gastral cavity is vexed, three YIN malaria (malaria pathogen in three YIN) disease, heating do not heal, end empty YANG-depletion etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 898th page).

Fructus Corni nature and flavor acid, puckery, tepor.Return liver, kidney channel.Has liver and kidney tonifying, the effect of essence astringing and desertion stemming.Can treat vertigo and tinnitus, soreness of waist and knee joint, impotence and seminal emission, enuresis frequent micturition, bleeding not during menses, profuse sweating collapse.Interior-heat is quenched one's thirst etc.(the 22nd page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).

Rhizoma Curcumae nature and flavor hardship, suffering, temperature.Return liver, spleen channel.Have the circulation of qi promoting removing blood stasis with potent drugs, the removing food stagnancy pain relieving is changed poly-eliminating mass, the effect of antiearly pregnancy.Can treat that trusted subordinate's distending pain, lump in the abdomen, dyspepsia do not disappear, hepatosplenomegaly, abdominal pain due to blood stasis, amenorrhea due to stagnation of blood, cervical erosion, traumatic injury have a pain etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 995th page).

Cortex Dictamni nature and flavor hardship, cold.Return spleen, stomach, urinary bladder channel.Has heat clearing and damp drying, the antidotal effect of dispeling the wind.Can treat damp and hot sore, yellow fluid is dripping, eczema, rubella, scabies skin ulcer leprosy, rheumatism pyretic arthralgia, jaundice dark coloured urine etc.(the 83rd page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).

The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Radix Rehmanniae, the Rhizoma Anemarrhenae and Fructus Ligustri Lucidi; With Radix Polygoni Multiflori, Radix Salviae Miltiorrhizae, Rhizoma Smilacis Glabrae, Radix Bupleuri, Rhizoma Alismatis and Poria is ministerial drug; With Fructus Corni, Rhizoma Curcumae and Cortex Dictamni is adjuvant.All medicines are harmonious, and are total to the tool clearing away heat-fire, the effect of blood nourishing and hair.The treatment seborrheic alopecia has determined curative effect, has no side effect taking convenience, cheap characteristics.

Clinical drug of the present invention uses the result to show that following advantage is arranged:

1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment seborrheic alopecia of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.

2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.

3, the present invention not only can effectively treat seborrheic alopecia, and the prevention of seborrheic alopecia is also had good effect, and the treatment seborrheic alopecia has determined curative effect, has no side effect taking convenience, cheap characteristics.

For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment seborrheic alopecia; Treatment seborrheic alopecia patient 20 examples, male's 13 examples, women's 7 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.One month is a course of treatment, take continuously three the course of treatment observe the curative effect.10 examples of fully recovering account for 50%, and 9 examples that take a turn for the better account for 40%, and more 2 examples do not account for 10%, and total effective rate reaches 90%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.

The specific embodiment

The embodiment decoction takes by weighing raw material by following weight:

3 parts of 3 parts of Fructus Ligustri Lucidi of 3 parts of Rhizoma Anemarrhenaes of Radix Rehmanniae

2 parts of 2 parts of Rhizoma Smilacis Glabraes of 2 parts of Radix Salviae Miltiorrhizaes of Radix Polygoni Multiflori

2 parts in 2 parts of Poria of 2 portions of Rhizoma Alismatis of Radix Bupleuri

1 part of 1 part of Cortex Dictamni of 1 part of Rhizoma Curcumae of Fructus Corni

Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5～2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1～1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment seborrheic alopecia that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.One month is a course of treatment.

Claims (3)

1, a kind of Chinese medicine preparation for the treatment of seborrheic alopecia is characterized in that it is made by the following weight proportion raw material:

1.5～6 parts of 1.5～6 parts of Fructus Ligustri Lucidi of 1.5～6 parts of Rhizoma Anemarrhenaes of Radix Rehmanniae

1.0～4 parts of 1.0～4 parts of Rhizoma Smilacis Glabraes of 1.0～4 parts of Radix Salviae Miltiorrhizaes of Radix Polygoni Multiflori

1.0～4 parts in 1.0～4 parts of Poria of 1.0～4 portions of Rhizoma Alismatis of Radix Bupleuri

0.1～2 part of 0.1～2 part of Cortex Dictamni of 0.1～2 part of Rhizoma Curcumae of Fructus Corni.

2, a kind of Chinese medicine preparation for the treatment of seborrheic alopecia according to claim 1, wherein the weight proportion of each raw material is:

2.5～3.5 parts of 2.5～3.5 parts of Fructus Ligustri Lucidi of 2.5～3.5 parts of Rhizoma Anemarrhenaes of Radix Rehmanniae

1.5～2.5 parts of 1.5～2.5 parts of Rhizoma Smilacis Glabraes of 1.5～2.5 parts of Radix Salviae Miltiorrhizaes of Radix Polygoni Multiflori

1.5～2.5 parts in 1.5～2.5 parts of Poria of 1.5～2.5 portions of Rhizoma Alismatis of Radix Bupleuri

0.5～1.5 part of 0.5～1.5 part of Cortex Dictamni of 0.5～1.5 part of Rhizoma Curcumae of Fructus Corni.

3, a kind of Chinese medicine preparation for the treatment of seborrheic alopecia according to claim 1, wherein the weight proportion of each raw material is:

3 parts of 3 parts of Fructus Ligustri Lucidi of 3 parts of Rhizoma Anemarrhenaes of Radix Rehmanniae

2 parts of 2 parts of Rhizoma Smilacis Glabraes of 2 parts of Radix Salviae Miltiorrhizaes of Radix Polygoni Multiflori

2 parts in 2 parts of Poria of 2 portions of Rhizoma Alismatis of Radix Bupleuri

1 part of 1 part of Cortex Dictamni of 1 part of Rhizoma Curcumae of Fructus Corni.