CN101028506A - Chinese-medicinal decoction for treating difficult menstruation - Google Patents

Chinese-medicinal decoction for treating difficult menstruation Download PDF

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Publication number
CN101028506A
CN101028506A CN 200710065495 CN200710065495A CN101028506A CN 101028506 A CN101028506 A CN 101028506A CN 200710065495 CN200710065495 CN 200710065495 CN 200710065495 A CN200710065495 A CN 200710065495A CN 101028506 A CN101028506 A CN 101028506A
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parts
rhizoma
pain
dysmenorrhea
chinese medicine
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CN 200710065495
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CN101028506B (en
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王信锁
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Beijing new China International Pharmaceutical Research Institute
Beijing Sino US Joint Institute of innovation and international difficult diseases
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Beijing Yixintang Medicine Institute
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Abstract

A Chinese medicine in the form of decoction for treating menalgia is prepared from more than 10 Chinese-medicinal materials including Chinese angelica root, Chuan- xiong rhizome, white peony root, cinnamon bark, etc.

Description

A kind of Chinese medicine decoction for the treatment of dysmenorrhea
Technical field
The present invention relates to a kind of Chinese medicine decoction for the treatment of dysmenorrhea, is that a kind of dysmenorrhea for the treatment of is the Chinese medicine decoction of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Dysmenorrhea is meant that the women in menstrual period and front and back thereof, lower abdomen or flank pain occur, even pain and waist sacrum, sends out along with menstrual cycle at every turn, and severe patient can be accompanied nausea and vomiting, dripping cold sweat, deadly cold hand and foot, even faints, and brings influence to the work life.Dysmenorrhea is sent out after 15~25 years old and menophania 6 months well in two years, is one of adolescence common sympton.Its sickness rate report differs, and accounts for 42%~90%, and wherein severe pain is through accounting for 18%.Dysmenorrhea belongs to Chinese medicine " abdominal pain during menstruation " category.
Chinese medicine thinks that special physiological environment is relevant before and after generation and the plain body factor of dysmenorrhea and menstrual period, menstrual period.Between non-menstrual period, dash to appoint QI and blood gentle, paathogenic factor can not cause dash appoint, the uterus stasis of blood stagnates or not enough, so pain does not take place.And before and after menstrual period or menstrual period, it is excessive that the sea of blood rushes down by completely being full of, and prosperous QI and blood changes anxious poly-the uterus QI and blood to empty temporarily through the back by arrogant blood, and paathogenic factor is taken the opportunity and done, and makes QI-blood circulation not smooth, and the uterus menses circulate and are obstructed consequently " stagnation of QI and blood may bring about pain "; Or cause that dash to appoint a uterus to lose in moistening foster, " not flourish and pain ".Its mechanism has branch cold, hot, empty, reality is many with excess syndrome.
Western medicine thinks that dysmenorrhea is because the spastic contraction of uterus muscle causes tissue ischemia to cause.Cause the former of uterus muscle spasm because cervical canal is narrow, the excessive retroversioflexion in uterus, the menses circulation is not smooth, and uterine contraction must be strengthened in the uterus could discharge menses, thereby how in the 1st~2 day dysmenorrhea of menstruation, after a large amount of menses were discharged, pain disappeared immediately.In addition.When uterine hypoplasia, deformity etc., uterus muscle produces inharmonious contraction, also can cause dysmenorrhea.And strip off when intrauterine film monoblock, consequently discharge is not smooth, causes spasmodic dysmenorrhea person, is called membranous dysmenorrhea.Sometimes spiritual hypertonicity, hyperesthesia, overwork, catch cold, living habit changes or when health status is bad, all dysmenorrhea can take place.
Modern medicine generally takes analgesic, tranquilizer to conciliate symptomatic treatments such as painful agent, though but immediate pain alleviating, next time is still.Also available hormone suppresses ovulation, but is not inconsistent and women's physiological.Adopt the inhibitor such as the alleviating pains such as acidum clofenamicum, mefenamic acid etc. and indometacin of prostaglandin synthetase in recent years, but certain side effect is arranged.The effect of Chinese medicine primary dysmenorrhea is adhered to taking medicine as if the patient certainly, and treating both the principal and the secondary aspects of a disease at the same time has obtained significant curative effect mostly.Press for development at present and promptly have remarkable analgesic activity and can thoroughly eradicate the specific drug of the Chinese medicine of the cause of disease again, so that extensive use clinically is that extensive patients is removed suffering of illness as dysmenorrhea.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine decoction for the treatment of dysmenorrhea.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by the following weight proportion raw material:
1.5~6 parts in 2.5~10 parts of Semen Persicaes of 2.5~10 parts of Rhizoma Corydalis of Radix Angelicae Sinensis
1.5~6 parts of 1.5~6 parts of Radixs Linderae of 2.5~10 portions of Caulis Spatholobis of the Radix Paeoniae Alba
0.1~2 part of 1.5~6 portions of Rhizoma Zingiberis of 1.5~6 parts of Radix Morindae Officinaliss of Rhizoma Chuanxiong
0.1~2 part of 0.1~2 portion of Cortex Cinnamomi of 1.5~6 parts of Fructus Foeniculi of Rhizoma Cyperi
The weight proportion of each raw material of optimization formula of the present invention is:
2.5~3.5 parts in 3.0~7.0 parts of Semen Persicaes of 3.0~7.0 parts of Rhizoma Corydalis of Radix Angelicae Sinensis
2.5~3.5 parts of 2.5~3.5 parts of Radixs Linderae of 3.0~7.0 portions of Caulis Spatholobis of the Radix Paeoniae Alba
0.5~1.5 part of 2.5~3.5 portions of Rhizoma Zingiberis of 2.5~3.5 parts of Radix Morindae Officinaliss of Rhizoma Chuanxiong
0.5~1.5 part of 0.5~1.5 portion of Cortex Cinnamomi of 2.5~3.5 parts of Fructus Foeniculi of Rhizoma Cyperi
The weight proportion of each raw material of optimum formula of the present invention is:
3 parts in 5 parts of Semen Persicaes of 5 parts of Rhizoma Corydalis of Radix Angelicae Sinensis
3 parts of 3 parts of Radixs Linderae of 5 portions of Caulis Spatholobis of the Radix Paeoniae Alba
1 part of 3 portions of Rhizoma Zingiberis of 3 parts of Radix Morindae Officinaliss of Rhizoma Chuanxiong
1 part of 1 portion of Cortex Cinnamomi of 3 parts of Fructus Foeniculi of Rhizoma Cyperi
Drug action mechanism among the present invention is as follows:
The Radix Angelicae Sinensis nature and flavor are sweet, hot, warm.Return liver, the heart, spleen channel.Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, the effect of loosening bowel to relieve constipation.Can be used for blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea stimulates the menstrual flow, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, traumatic injury, ulcer sores etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 553rd page).
Radix Paeoniae Alba nature and flavor hardship, acid, be slightly cold.Return liver, spleen channel.Effect with suppressing the hyperactive liver pain relieving, nourishing blood for regulating menstruation, astringing YIN to stop sweating, antibiotic, thrombocytosis.Can treat that the pain over the hypochondriac region, dysentery stomachache, night sweat, fever due to yin deficiency, menoxenia, metrorrhagia, leukorrhagia, headache are dizzy, limb pain twin, blood deficiency and yellow complexion etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 432nd page).
Rhizoma Corydalis nature and flavor suffering, hardship, wet.Return liver, spleen channel.Have and invigorate blood circulation, promoting the circulation of QI, analgesic effect.Can treat the breast side of body, epigastric pain, amenorrhea dysmenorrhea, postpartum stagnation, treating swelling and pain by traumatic injury etc. (Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 680th page).
Rhizoma Chuanxiong nature and flavor suffering, perfume (or spice).Return liver, gallbladder, pericardium channel.Has blood-activating and qi-promoting, the effect of wind-expelling pain-stopping.Can treat menoxenia, amenorrhea dysmenorrhea, difficult labour, lump in the abdomen stomachache, the twinge of the breast side of body, arthralgia due to cold clonic spasm of the muscle, tumbling and swelling, headache due to pathogenic wind-heat, rheumatic arthralgia, skin infection swells and ache, placenta retention, cerebral ischemia, coronary heart disease, angina pectoris, atherosclerosis, hypertension, leukopenia due to the radiotherapy, chemotherapy, juvenile myopia, vitamin e deficiency, flu is dizzy, external plug nose treating malaria disease etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 171st page).
Rhizoma Cyperi property of medicine suffering, sweet, little hardship, flat.Return liver, tri-jiao channel.Has the resolving depression of regulating the flow of vital energy, regulating menstruation, antiabortive effect.Can treat distending pain over the hypochondrium, distending pain of the breast, hernia pain, menoxenia, gastral cavity abdomen feeling of fullness pain, belch acid regurgitation, vomiting and nausea, abdominal pain during menstruation, bleeding not during menses, frequent fetal movement etc.(the 2341st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Caulis Spatholobi nature and flavor hardship, sweet, warm.Return liver, kidney channel.Have and enrich blood, invigorate blood circulation, the effect of collateral dredging.Can treat menoxenia, blood deficiency and yellow complexion, paralysis and numbness, rheumatic arthralgia etc.(the 151st page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
Radix Morindae Officinalis nature and flavor suffering, sweet, tepor.Return liver, kidney channel.Effect with kidney-replenishing, strengthening bone and muscle, wind-damp dispelling.Can treat impotence and seminal emission, cold womb is infertile, menoxenia, and cold and pain in the lower abdomen, rheumatic arthralgia, the muscles and bones flaccidity is soft etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 350th page).
Semen Persicae property of medicine hardship, sweet, mild toxicity.GUIXIN, liver, large intestine channel.Has blood circulation promoting and blood stasis dispelling, the effect of loosening bowel to relieve constipation.Can treat dysmenorrhea, amenorrhea due to stagnation of blood, the stagnant stomachache of the stasis of blood in puerperal , mass in the abdomen caking, traumatic injury, swelling and pain due to blood stasis, lung abscess, acute appendicitis, dryness of the intestine constipation etc.(the 2542nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Linderae property of medicine suffering, temperature.Return spleen, stomach, liver, kidney, urinary bladder channel.Have promoting the circulation of QI to relieve pain, the effect of warming kidney for dispelling cold.It is vexed to treat fullness in the chest and hypochondrium, abdominal distention, headache, colic of cold type pain, dysmenorrhea and puerperal abdonimal pain, frequent micturition, the enuresis etc.(the 655th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Rhizoma Zingiberis property of medicine suffering, heat.Return spleen, stomach, the heart, lung meridian.Have warming spleen and stomach for dispelling cold, recuperating depleted YANG is promoted blood circulation, the effect of warm arteries and veins dissipating fluid-retention.Can treat coldness and pain in the epigastrium, vomiting is had loose bowels, and YANG-depletion is fainted contrary, and arthralgia due to cold-dampnes, cold fluid-retention are breathed with cough etc.(the 100th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Fructus Foeniculi nature and flavor suffering, temperature.Return the liver,kidney,spleen,bladder warp.Has dispersing cold for relieving pain, the effect of regulating qi-flowing for harmonizing stomach.Can treat solid tumor, gastrointestinal tract tumor and cold syndrome of the stomach pain, colic of cold type stomachache, testis swelling and hanging down of either of the testes pain, cold and pain in the lower abdomen, abdominal distention, dyspepsia, lack of appetite and vomiting, hydrocele of testis, schistosomicide, lumbago due to renal deficiency, vomiting, dried, beriberi caused by pathogenic damp, asthma etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 206th page).
Cortex Cinnamomi property of medicine suffering, sweet, heat.Return kidney, spleen, the heart, Liver Channel.It is supporing yang to have the fire of benefit, dispersing cold for relieving pain, the effect of warming the meridian and promoting blood circulation.Can treat insufficiency of kidney-YANG, the aversion to cold and cold limbs of decline of the fire from the gate of life, soreness of the waist and knees, impotence and seminal emission, dysuria or frequency, the dyspnea with rapid and short breath of losing heart, all diseases of edema oliguria; Decline of the fire from the gate of life, fire is Gui Yuan not, floating YANG, refusing yang, and heat in the upper and cold in the lower, the flushed complexion cold foot, dizziness and tinnitus, dispute is rotten broken; Spleen-kidney vacuity cold, coldness and pain in the epigastrium, decreased food intake loose stool; Lumbago due to renal deficiency; Arthralgia due to cold-dampnes; Colic of cold type pain; Cold womb is infertile, the dysmenorrhea amenorrhea, and the stasis of blood stagnated and suffered from abdominal pain puerperal; Carbuncle of yin nature multiple abscess, or deficiency and coldness carbuncle and ulcer difficulty in discharging of pus, or do not hold back after bursting etc.(the 1223rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Radix Angelicae Sinensis, the Radix Paeoniae Alba and Rhizoma Corydalis; With Rhizoma Chuanxiong, Rhizoma Cyperi, Caulis Spatholobi, Radix Morindae Officinalis, Semen Persicae and the Radix Linderae is ministerial drug; With Rhizoma Zingiberis and, Fructus Foeniculi and Cortex Cinnamomi be adjuvant.All medicines are harmonious, and are total to the tool dispelling cold by warming the meridian, the effect of blood-activating analgetic.The treatment dysmenorrhea has determined curative effect, has no side effect taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment dysmenorrhea of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through animal acute toxicity experiment the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, the present invention need not decoct, no bitterness sense, rich in proteins in the medicine, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat dysmenorrhea, and the prevention of dysmenorrhea is also had good effect, and the treatment dysmenorrhea has determined curative effect, has no side effect taking convenience, cheap characteristics.Further specify medicine of the present invention to treatment TREATMENT OF DYSMENORRHOEA effect below by the clinical practice example.
The dysmenorrhea diagnosis basis: 1. menstrual period or before and after row lower abdomen pain, pain and waist sacrum are very then fainted.Be periodical attack.2. good sending out in young maiden.3. get rid of and suffer from abdominal pain due to the pelvic cavity organic disease.(the 363rd page of chief editor's " traditional Chinese medical science disease diagnosis and treatment standard and prescription are selected for use " People's Health Publisher's calendar year 2001 version such as Dai Shen)
Dysmenorrhea efficacy assessment standard: 1. cure: pain disappears, and continuous 3 menstrual cycle are not seen recurrence.2. take a turn for the better: pain relief or pain disappear, but can not keep more than 3 months.3. do not heal: pain is not seen improvement.(the 367th page of chief editor's " traditional Chinese medical science disease diagnosis and treatment standard and prescription are selected for use " People's Health Publisher's calendar year 2001 version such as Dai Shen)
For showing medicine of the present invention, as follows through clinical test results to treatment TREATMENT OF DYSMENORRHOEA effect; Treatment dysmenorrhea patient 24 examples, the age is 12~25 years old.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.One month is a course of treatment, take continuously three the course of treatment observe the curative effect.Cure 18 examples and account for 75%, 4 examples that take a turn for the better account for 16.7%, and more 2 examples do not account for 8.3%, and total effective rate reaches 91.7%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
The embodiment decoction takes by weighing raw material by following weight:
3 parts in 5 parts of Semen Persicaes of 5 parts of Rhizoma Corydalis of Radix Angelicae Sinensis
3 parts of 3 parts of Radixs Linderae of 5 portions of Caulis Spatholobis of the Radix Paeoniae Alba
1 part of 3 portions of Rhizoma Zingiberis of 3 parts of Radix Morindae Officinaliss of Rhizoma Chuanxiong
1 part of 1 portion of Cortex Cinnamomi of 3 parts of Fructus Foeniculi of Rhizoma Cyperi
Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5~2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1~1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The dysmenorrhea decoction plastic packaging that the present invention makes is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.One month is a course of treatment.

Claims (3)

1, a kind of Chinese medicine decoction for the treatment of dysmenorrhea is characterized in that it is made by the following weight proportion raw material:
1.5~6 parts in 2.5~10 parts of Semen Persicaes of 2.5~10 parts of Rhizoma Corydalis of Radix Angelicae Sinensis
1.5~6 parts of 1.5~6 parts of Radixs Linderae of 2.5~10 portions of Caulis Spatholobis of the Radix Paeoniae Alba
0.1~2 part of 1.5~6 portions of Rhizoma Zingiberis of 1.5~6 parts of Radix Morindae Officinaliss of Rhizoma Chuanxiong
0.1~2 part of 0.1~2 portion of Cortex Cinnamomi of 1.5~6 parts of Fructus Foeniculi of Rhizoma Cyperi
2, a kind of Chinese medicine decoction for the treatment of dysmenorrhea according to claim 1, wherein the weight proportion of each raw material is:
2.5~3.5 parts in 3.0~7.0 parts of Semen Persicaes of 3.0~7.0 parts of Rhizoma Corydalis of Radix Angelicae Sinensis
2.5~3.5 parts of 2.5~3.5 parts of Radixs Linderae of 3.0~7.0 portions of Caulis Spatholobis of the Radix Paeoniae Alba
0.5~1.5 part of 2.5~3.5 portions of Rhizoma Zingiberis of 2.5~3.5 parts of Radix Morindae Officinaliss of Rhizoma Chuanxiong
0.5~1.5 part of 0.5~1.5 portion of Cortex Cinnamomi of 2.5~3.5 parts of Fructus Foeniculi of Rhizoma Cyperi
3, a kind of Chinese medicine decoction for the treatment of dysmenorrhea according to claim 1, wherein the weight proportion of each raw material is:
3 parts in 5 parts of Semen Persicaes of 5 parts of Rhizoma Corydalis of Radix Angelicae Sinensis
3 parts of 3 parts of Radixs Linderae of 5 portions of Caulis Spatholobis of the Radix Paeoniae Alba
1 part of 3 portions of Rhizoma Zingiberis of 3 parts of Radix Morindae Officinaliss of Rhizoma Chuanxiong
1 part of 1 portion of Cortex Cinnamomi of 3 parts of Fructus Foeniculi of Rhizoma Cyperi
CN200710065495A 2007-04-16 2007-04-16 Chinese-medicinal decoction for treating difficult menstruation Expired - Fee Related CN101028506B (en)

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102008584A (en) * 2010-12-14 2011-04-13 句容市边城卫生院 Drug for treating kidney yang deficiency
CN102793884A (en) * 2012-09-05 2012-11-28 山东省中医药研究院 Chinese medical plaster for treating dysmenorrhea and preparation method thereof
CN103041345A (en) * 2012-12-31 2013-04-17 王爱云 Agent for treating dysmenorrhea
CN104383517A (en) * 2014-12-15 2015-03-04 广东岭南职业技术学院 Sugar with efficiency of relieving dysmenorrheal and preparation method thereof
CN105031122A (en) * 2015-07-01 2015-11-11 青岛大学 Externally applied superfine-powder traditional Chinese medicament for treating dysmenorrhea and external massage equipment for treating dysmenorrhea by using externally applied superfine-powder traditional Chinese medicament
CN108114264A (en) * 2018-02-09 2018-06-05 贵州苗康医药科技有限公司 A kind of external preparation of warm the womb

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102008584A (en) * 2010-12-14 2011-04-13 句容市边城卫生院 Drug for treating kidney yang deficiency
CN102008584B (en) * 2010-12-14 2011-11-30 句容市边城卫生院 Drug for treating cold-aggregating qi-stasis dysmenorrhea
CN102793884A (en) * 2012-09-05 2012-11-28 山东省中医药研究院 Chinese medical plaster for treating dysmenorrhea and preparation method thereof
CN102793884B (en) * 2012-09-05 2014-01-29 山东省中医药研究院 Chinese medical plaster for treating dysmenorrhea and preparation method thereof
CN103041345A (en) * 2012-12-31 2013-04-17 王爱云 Agent for treating dysmenorrhea
CN104383517A (en) * 2014-12-15 2015-03-04 广东岭南职业技术学院 Sugar with efficiency of relieving dysmenorrheal and preparation method thereof
CN105031122A (en) * 2015-07-01 2015-11-11 青岛大学 Externally applied superfine-powder traditional Chinese medicament for treating dysmenorrhea and external massage equipment for treating dysmenorrhea by using externally applied superfine-powder traditional Chinese medicament
CN108114264A (en) * 2018-02-09 2018-06-05 贵州苗康医药科技有限公司 A kind of external preparation of warm the womb

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