CN101048176B - 用于口腔粘膜给药的液体过敏反应疫苗制剂 - Google Patents

用于口腔粘膜给药的液体过敏反应疫苗制剂 Download PDF

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Publication number
CN101048176B
CN101048176B CN2005800364100A CN200580036410A CN101048176B CN 101048176 B CN101048176 B CN 101048176B CN 2005800364100 A CN2005800364100 A CN 2005800364100A CN 200580036410 A CN200580036410 A CN 200580036410A CN 101048176 B CN101048176 B CN 101048176B
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China
Prior art keywords
allergen
oxygen
containing metal
use according
allergens
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Expired - Fee Related
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CN2005800364100A
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English (en)
Chinese (zh)
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CN101048176A (zh
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J·布里莫奈斯
J·基尔德斯加德
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ALK Abello AS
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ALK Abello AS
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/35—Allergens
    • A61K39/36—Allergens from pollen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/542—Mucosal route oral/gastrointestinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pulmonology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Transplantation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CN2005800364100A 2004-09-27 2005-09-22 用于口腔粘膜给药的液体过敏反应疫苗制剂 Expired - Fee Related CN101048176B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US61389204P 2004-09-27 2004-09-27
US60/613,892 2004-09-27
DKPA200401468 2004-09-27
DKPA200401468 2004-09-27
PCT/DK2005/000601 WO2006034707A1 (en) 2004-09-27 2005-09-22 Liquid allergy vaccine formulation for oromucosal administration

Publications (2)

Publication Number Publication Date
CN101048176A CN101048176A (zh) 2007-10-03
CN101048176B true CN101048176B (zh) 2012-01-11

Family

ID=35431828

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2005800364100A Expired - Fee Related CN101048176B (zh) 2004-09-27 2005-09-22 用于口腔粘膜给药的液体过敏反应疫苗制剂

Country Status (16)

Country Link
US (1) US20060115499A1 (enExample)
EP (1) EP1793853B1 (enExample)
JP (1) JP4976298B2 (enExample)
KR (1) KR20070057963A (enExample)
CN (1) CN101048176B (enExample)
AT (1) ATE421330T1 (enExample)
AU (1) AU2005289193A1 (enExample)
CA (1) CA2581815A1 (enExample)
DE (1) DE602005012522D1 (enExample)
DK (1) DK1793853T3 (enExample)
ES (1) ES2321425T3 (enExample)
IL (1) IL182135A0 (enExample)
MX (1) MX2007003609A (enExample)
NO (1) NO20071636L (enExample)
RU (1) RU2007115920A (enExample)
WO (1) WO2006034707A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2006310881B2 (en) * 2005-11-04 2012-07-19 Alk-Abello A/S Use of a liquid allergy vaccine formulation for oromucosal administration
ES2370043T3 (es) * 2007-03-28 2011-12-12 Alk-Abelló A/S Uso de una formulación de vacuna de la alergia coadyuvada para administración subcutánea.
DE202008006598U1 (de) 2008-04-11 2008-10-02 Alk-Abelló A/S Allergie-Impfstoff-Formulierung zur mucosalen Verabreichung
CA2739557A1 (en) * 2008-10-15 2010-04-22 Alk-Abello A/S Pharmaceutical product for up-dosing of allergy vaccine
US9545455B2 (en) * 2009-04-29 2017-01-17 Pravin K. Muniyappa Device and method for the diagnosis of gastrointestinal allergy
CN106421775B (zh) * 2015-08-12 2020-12-01 普莱柯生物工程股份有限公司 一种疫苗用佐剂及含该佐剂的疫苗组合物和其应用
BR102017026619A2 (pt) 2017-02-15 2018-10-30 Euroimmun Medizinische Labordiagnostika Ag ensaio melhorado para a diagnose de alergia a amendoim

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3148121A (en) * 1960-01-27 1964-09-08 Miles Lab Water-insoluble whole inhalant complex and method of making same
US3329564A (en) * 1965-06-28 1967-07-04 Parke Davis & Co Antacid preparations and means of producing the same
US4233288A (en) * 1979-03-12 1980-11-11 Cornell John A Gum emulsified liquid package for delivering and preserving liquid content in the mouth
US4341763A (en) * 1981-03-10 1982-07-27 Smithkline-Rit Methods of vaccinating humans against rotavirus infection
JPS61238728A (ja) * 1985-04-16 1986-10-24 Mitsui Norin Kk 茶葉抽出物と活性水酸化アルミニウムとの抗潰瘍性複合体
US6103243A (en) * 1985-05-15 2000-08-15 Biotechnology Australia Pty, Ltd Oral vaccines
KR900701304A (ko) * 1988-05-05 1990-12-01 루이즈 츄이 콜린스 에이미 사람 및/또는 동물용 알레르겐 탈감작제
US5032405A (en) * 1989-09-27 1991-07-16 Warner-Lambert Company Oral pharmaceutical composition for acid sensitive proteinaceous agents
US5443832A (en) * 1990-04-16 1995-08-22 Institut Swisse De Recherches Experimentales Sur Le Cancer Hydroxyapatite-antigen conjugates and methods for generating a poly-Ig immune response
EP0484621A3 (en) * 1990-07-11 1992-08-26 American Cyanamid Company Efficacious vaccines against bordetella pertussis comprising a combination of individually purified pertussis antigens
US5338543A (en) * 1992-02-27 1994-08-16 Ambico, Inc. Thimerosal inactivated mycoplasma hyopneumoniae vaccine
JP3414539B2 (ja) * 1994-05-11 2003-06-09 有限会社ドット 経鼻吸収用組成物
US5985312A (en) * 1996-01-26 1999-11-16 Brown University Research Foundation Methods and compositions for enhancing the bioadhesive properties of polymers
US5985287A (en) * 1996-08-29 1999-11-16 Genesis Research And Development Corporation Limited Compounds and methods for treatment and diagnosis of mycobacterial infections
US20020068090A1 (en) * 1999-02-03 2002-06-06 Bell Steve J. D. Calcium phosphate particles as mucosal adjuvants
CN1338947B (zh) * 1999-02-05 2012-11-14 爱尔开-阿贝优公司 粘膜递送系统
US6248363B1 (en) * 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
US20020051794A1 (en) * 2000-08-09 2002-05-02 Alk-Abello A/S Novel parenteral vaccine formulations and uses thereof
GB0020089D0 (en) * 2000-08-15 2000-10-04 Smithkline Beecham Biolog Vaccine Composition
KR100919914B1 (ko) * 2000-11-16 2009-10-06 알크-아벨로 에이/에스 신규한 돌연변이체 알레르겐
WO2003096869A2 (en) * 2002-05-16 2003-11-27 Alk Abelló A/S Recombinant bet. v. 1. allergen mutants, methods and process thereof
MXPA05005528A (es) * 2002-11-26 2006-04-05 Alk Abello As Producto farmaceutico de alergeno.

Also Published As

Publication number Publication date
JP2008514557A (ja) 2008-05-08
JP4976298B2 (ja) 2012-07-18
EP1793853B1 (en) 2009-01-21
KR20070057963A (ko) 2007-06-07
US20060115499A1 (en) 2006-06-01
MX2007003609A (es) 2007-06-05
AU2005289193A1 (en) 2006-04-06
ATE421330T1 (de) 2009-02-15
WO2006034707A1 (en) 2006-04-06
HK1106447A1 (en) 2008-03-14
CN101048176A (zh) 2007-10-03
ES2321425T3 (es) 2009-06-05
IL182135A0 (en) 2007-07-24
DK1793853T3 (da) 2009-04-14
NO20071636L (no) 2007-06-14
CA2581815A1 (en) 2006-04-06
RU2007115920A (ru) 2008-11-10
EP1793853A1 (en) 2007-06-13
DE602005012522D1 (de) 2009-03-12

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