CN101048176B - 用于口腔粘膜给药的液体过敏反应疫苗制剂 - Google Patents
用于口腔粘膜给药的液体过敏反应疫苗制剂 Download PDFInfo
- Publication number
- CN101048176B CN101048176B CN2005800364100A CN200580036410A CN101048176B CN 101048176 B CN101048176 B CN 101048176B CN 2005800364100 A CN2005800364100 A CN 2005800364100A CN 200580036410 A CN200580036410 A CN 200580036410A CN 101048176 B CN101048176 B CN 101048176B
- Authority
- CN
- China
- Prior art keywords
- anaphylactogen
- metal salt
- purposes
- oxygen metal
- concentration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/35—Allergens
- A61K39/36—Allergens from pollen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/542—Mucosal route oral/gastrointestinal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Transplantation (AREA)
- Ophthalmology & Optometry (AREA)
- Pulmonology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Description
Claims (13)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US61389204P | 2004-09-27 | 2004-09-27 | |
DKPA200401468 | 2004-09-27 | ||
US60/613,892 | 2004-09-27 | ||
DKPA200401468 | 2004-09-27 | ||
PCT/DK2005/000601 WO2006034707A1 (en) | 2004-09-27 | 2005-09-22 | Liquid allergy vaccine formulation for oromucosal administration |
Publications (2)
Publication Number | Publication Date |
---|---|
CN101048176A CN101048176A (zh) | 2007-10-03 |
CN101048176B true CN101048176B (zh) | 2012-01-11 |
Family
ID=35431828
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN2005800364100A Expired - Fee Related CN101048176B (zh) | 2004-09-27 | 2005-09-22 | 用于口腔粘膜给药的液体过敏反应疫苗制剂 |
Country Status (17)
Country | Link |
---|---|
US (1) | US20060115499A1 (zh) |
EP (1) | EP1793853B1 (zh) |
JP (1) | JP4976298B2 (zh) |
KR (1) | KR20070057963A (zh) |
CN (1) | CN101048176B (zh) |
AT (1) | ATE421330T1 (zh) |
AU (1) | AU2005289193A1 (zh) |
CA (1) | CA2581815A1 (zh) |
DE (1) | DE602005012522D1 (zh) |
DK (1) | DK1793853T3 (zh) |
ES (1) | ES2321425T3 (zh) |
HK (1) | HK1106447A1 (zh) |
IL (1) | IL182135A0 (zh) |
MX (1) | MX2007003609A (zh) |
NO (1) | NO20071636L (zh) |
RU (1) | RU2007115920A (zh) |
WO (1) | WO2006034707A1 (zh) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20090297564A1 (en) * | 2005-11-04 | 2009-12-03 | Domingo Barber Hernandez | Use of a Liquid Allergy Vaccine Formulation for Oromucosal Administration |
ES2370043T3 (es) * | 2007-03-28 | 2011-12-12 | Alk-Abelló A/S | Uso de una formulación de vacuna de la alergia coadyuvada para administración subcutánea. |
DE202008006598U1 (de) | 2008-04-11 | 2008-10-02 | Alk-Abelló A/S | Allergie-Impfstoff-Formulierung zur mucosalen Verabreichung |
JP2012505856A (ja) * | 2008-10-15 | 2012-03-08 | アルク−アベッロ エイ/エス | アレルギーワクチンの用量漸増のための医薬品 |
WO2010127144A1 (en) | 2009-04-29 | 2010-11-04 | Muniyappa Pravin K | Device and method for the diagnosis of gastrointestinal allergy |
CN106421775B (zh) * | 2015-08-12 | 2020-12-01 | 普莱柯生物工程股份有限公司 | 一种疫苗用佐剂及含该佐剂的疫苗组合物和其应用 |
BR102017026619A2 (pt) | 2017-02-15 | 2018-10-30 | Euroimmun Medizinische Labordiagnostika Ag | ensaio melhorado para a diagnose de alergia a amendoim |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3148121A (en) * | 1960-01-27 | 1964-09-08 | Miles Lab | Water-insoluble whole inhalant complex and method of making same |
US3329564A (en) * | 1965-06-28 | 1967-07-04 | Parke Davis & Co | Antacid preparations and means of producing the same |
US4233288A (en) * | 1979-03-12 | 1980-11-11 | Cornell John A | Gum emulsified liquid package for delivering and preserving liquid content in the mouth |
US4341763A (en) * | 1981-03-10 | 1982-07-27 | Smithkline-Rit | Methods of vaccinating humans against rotavirus infection |
JPS61238728A (ja) * | 1985-04-16 | 1986-10-24 | Mitsui Norin Kk | 茶葉抽出物と活性水酸化アルミニウムとの抗潰瘍性複合体 |
US6103243A (en) * | 1985-05-15 | 2000-08-15 | Biotechnology Australia Pty, Ltd | Oral vaccines |
KR900701304A (ko) * | 1988-05-05 | 1990-12-01 | 루이즈 츄이 콜린스 에이미 | 사람 및/또는 동물용 알레르겐 탈감작제 |
US5032405A (en) * | 1989-09-27 | 1991-07-16 | Warner-Lambert Company | Oral pharmaceutical composition for acid sensitive proteinaceous agents |
US5443832A (en) * | 1990-04-16 | 1995-08-22 | Institut Swisse De Recherches Experimentales Sur Le Cancer | Hydroxyapatite-antigen conjugates and methods for generating a poly-Ig immune response |
EP0484621A3 (en) * | 1990-07-11 | 1992-08-26 | American Cyanamid Company | Efficacious vaccines against bordetella pertussis comprising a combination of individually purified pertussis antigens |
US5338543A (en) * | 1992-02-27 | 1994-08-16 | Ambico, Inc. | Thimerosal inactivated mycoplasma hyopneumoniae vaccine |
JP3414539B2 (ja) * | 1994-05-11 | 2003-06-09 | 有限会社ドット | 経鼻吸収用組成物 |
US5985312A (en) * | 1996-01-26 | 1999-11-16 | Brown University Research Foundation | Methods and compositions for enhancing the bioadhesive properties of polymers |
US5985287A (en) * | 1996-08-29 | 1999-11-16 | Genesis Research And Development Corporation Limited | Compounds and methods for treatment and diagnosis of mycobacterial infections |
US20020068090A1 (en) * | 1999-02-03 | 2002-06-06 | Bell Steve J. D. | Calcium phosphate particles as mucosal adjuvants |
CA2361377C (en) * | 1999-02-05 | 2009-02-03 | Alk-Abello A/S | Novel mucosal delivery system |
US6248363B1 (en) * | 1999-11-23 | 2001-06-19 | Lipocine, Inc. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
US20020051794A1 (en) * | 2000-08-09 | 2002-05-02 | Alk-Abello A/S | Novel parenteral vaccine formulations and uses thereof |
GB0020089D0 (en) * | 2000-08-15 | 2000-10-04 | Smithkline Beecham Biolog | Vaccine Composition |
MXPA03004174A (es) * | 2000-11-16 | 2004-12-02 | Alk Abello As | Alergenos mutantes novedosos. |
CN1668737A (zh) * | 2002-05-16 | 2005-09-14 | 阿尔克-阿贝洛有限公司 | 重组Bet.V.1过敏原突变体及其方法和制备 |
WO2004047793A1 (en) * | 2002-11-26 | 2004-06-10 | Alk-Abelló A/S | Pharmaceutical allergen product |
-
2005
- 2005-09-14 US US11/228,007 patent/US20060115499A1/en not_active Abandoned
- 2005-09-22 ES ES05784220T patent/ES2321425T3/es active Active
- 2005-09-22 RU RU2007115920/15A patent/RU2007115920A/ru not_active Application Discontinuation
- 2005-09-22 AT AT05784220T patent/ATE421330T1/de not_active IP Right Cessation
- 2005-09-22 CN CN2005800364100A patent/CN101048176B/zh not_active Expired - Fee Related
- 2005-09-22 EP EP05784220A patent/EP1793853B1/en not_active Not-in-force
- 2005-09-22 DK DK05784220T patent/DK1793853T3/da active
- 2005-09-22 CA CA002581815A patent/CA2581815A1/en not_active Abandoned
- 2005-09-22 KR KR1020077008914A patent/KR20070057963A/ko not_active Application Discontinuation
- 2005-09-22 MX MX2007003609A patent/MX2007003609A/es unknown
- 2005-09-22 JP JP2007532772A patent/JP4976298B2/ja not_active Expired - Fee Related
- 2005-09-22 AU AU2005289193A patent/AU2005289193A1/en not_active Abandoned
- 2005-09-22 DE DE602005012522T patent/DE602005012522D1/de active Active
- 2005-09-22 WO PCT/DK2005/000601 patent/WO2006034707A1/en active Application Filing
-
2007
- 2007-03-22 IL IL182135A patent/IL182135A0/en unknown
- 2007-03-28 NO NO20071636A patent/NO20071636L/no not_active Application Discontinuation
- 2007-11-08 HK HK07112118.5A patent/HK1106447A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP1793853A1 (en) | 2007-06-13 |
JP2008514557A (ja) | 2008-05-08 |
WO2006034707A1 (en) | 2006-04-06 |
ES2321425T3 (es) | 2009-06-05 |
RU2007115920A (ru) | 2008-11-10 |
ATE421330T1 (de) | 2009-02-15 |
KR20070057963A (ko) | 2007-06-07 |
US20060115499A1 (en) | 2006-06-01 |
CA2581815A1 (en) | 2006-04-06 |
EP1793853B1 (en) | 2009-01-21 |
DK1793853T3 (da) | 2009-04-14 |
MX2007003609A (es) | 2007-06-05 |
JP4976298B2 (ja) | 2012-07-18 |
DE602005012522D1 (de) | 2009-03-12 |
HK1106447A1 (en) | 2008-03-14 |
CN101048176A (zh) | 2007-10-03 |
IL182135A0 (en) | 2007-07-24 |
AU2005289193A1 (en) | 2006-04-06 |
NO20071636L (no) | 2007-06-14 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN101048176B (zh) | 用于口腔粘膜给药的液体过敏反应疫苗制剂 | |
Mullins | Echinacea‐associated anaphylaxis | |
TWI421091B (zh) | 包含以聚肌苷酸-聚胞苷酸為主之佐劑的黏膜免疫物質 | |
EP1814516B1 (en) | Use of a liquid allergy vaccine formulation for oromucosal administration | |
JP2011516521A (ja) | 花粉シーズン開始後の初回投薬での粘膜のアレルゲン−特異的免疫療法 | |
EP1146906B1 (en) | Mucosal delivery system | |
US20060171968A1 (en) | Method of preventive treatment of allergy by oromucosal administration of an allergy vaccine | |
CN102939099A (zh) | 使用减毒大肠杆菌不耐热肠毒素治疗过敏症 | |
CN101595126A (zh) | 第一屋尘螨2类过敏原用于治疗对第二屋尘螨2类过敏原的过敏症的用途 | |
CN101065146B (zh) | 通过过敏反应疫苗的粘膜给药预防性治疗过敏反应的方法 | |
CN101098711A (zh) | 通过口粘膜施用变态反应疫苗预防性治疗变态反应的方法 | |
EP2167084B1 (en) | An allergen dosage form comprising an antihistamine | |
CN1261161C (zh) | 复方干扰素诱生剂口含片 | |
ES2370043T3 (es) | Uso de una formulación de vacuna de la alergia coadyuvada para administración subcutánea. | |
ZA200702413B (en) | Liquid allergy vaccine formulation for oromucosal administration | |
Prasad | Noninjective Allergen-specific Immunotherapy | |
JP2018008908A (ja) | 人以外の陸上動物用のウイルス感染症に対する抗体誘導剤とその補助剤 | |
CN103933562A (zh) | 用于口腔粘膜给药的液体变态反应性疫苗制剂的用途 | |
CN1751685A (zh) | 治疗过敏性鼻炎的阿司咪唑新剂型 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
REG | Reference to a national code |
Ref country code: HK Ref legal event code: DE Ref document number: 1106447 Country of ref document: HK |
|
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
C56 | Change in the name or address of the patentee |
Owner name: ALK-ABELLO A/S Free format text: FORMER NAME: ALK-ABELLO A/S |
|
CP01 | Change in the name or title of a patent holder |
Address after: Holm Hess, Denmark Patentee after: Alk Abello AS Address before: Holm Hess, Denmark Patentee before: Alk Abello AS |
|
C17 | Cessation of patent right | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20120111 Termination date: 20130922 |