CN101006985A - 药用组合物 - Google Patents

药用组合物 Download PDF

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Publication number
CN101006985A
CN101006985A CNA2006101016820A CN200610101682A CN101006985A CN 101006985 A CN101006985 A CN 101006985A CN A2006101016820 A CNA2006101016820 A CN A2006101016820A CN 200610101682 A CN200610101682 A CN 200610101682A CN 101006985 A CN101006985 A CN 101006985A
Authority
CN
China
Prior art keywords
weight
preparation
pharmaceutically acceptable
hydroxypropyl emthylcellulose
content
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2006101016820A
Other languages
English (en)
Chinese (zh)
Inventor
B·V·帕里克
R·J·蒂姆科
W·J·阿迪克斯
Original Assignee
Zeneca Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10794541&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN101006985(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Zeneca Ltd filed Critical Zeneca Ltd
Publication of CN101006985A publication Critical patent/CN101006985A/zh
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/554Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/286Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
CNA2006101016820A 1996-05-31 1997-05-27 药用组合物 Pending CN101006985A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9611328.7 1996-05-31
GBGB9611328.7A GB9611328D0 (en) 1996-05-31 1996-05-31 Pharmaceutical compositions

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CNA2004100033798A Division CN1511532A (zh) 1996-05-31 1997-05-27 药用组合物

Publications (1)

Publication Number Publication Date
CN101006985A true CN101006985A (zh) 2007-08-01

Family

ID=10794541

Family Applications (3)

Application Number Title Priority Date Filing Date
CNA2004100033798A Pending CN1511532A (zh) 1996-05-31 1997-05-27 药用组合物
CNB971949611A Expired - Lifetime CN1142780C (zh) 1996-05-31 1997-05-27 药用组合物
CNA2006101016820A Pending CN101006985A (zh) 1996-05-31 1997-05-27 药用组合物

Family Applications Before (2)

Application Number Title Priority Date Filing Date
CNA2004100033798A Pending CN1511532A (zh) 1996-05-31 1997-05-27 药用组合物
CNB971949611A Expired - Lifetime CN1142780C (zh) 1996-05-31 1997-05-27 药用组合物

Country Status (31)

Country Link
EP (1) EP0907364B1 (enExample)
JP (5) JP2000511170A (enExample)
CN (3) CN1511532A (enExample)
AR (1) AR003662A1 (enExample)
AT (1) ATE222105T1 (enExample)
AU (1) AU727219B2 (enExample)
BR (1) BR9709271A (enExample)
CA (1) CA2251944C (enExample)
CZ (1) CZ293760B6 (enExample)
DE (1) DE69714739T2 (enExample)
DK (1) DK0907364T3 (enExample)
EG (1) EG24118A (enExample)
ES (1) ES2182079T3 (enExample)
GB (2) GB9611328D0 (enExample)
HR (1) HRP970299B1 (enExample)
HU (1) HU225152B1 (enExample)
ID (1) ID18352A (enExample)
IL (1) IL127222A (enExample)
MY (1) MY120120A (enExample)
NO (1) NO327801B1 (enExample)
NZ (1) NZ332198A (enExample)
PL (1) PL189887B1 (enExample)
PT (1) PT907364E (enExample)
RU (1) RU2201754C2 (enExample)
SI (1) SI0907364T1 (enExample)
SK (1) SK284131B6 (enExample)
TR (1) TR199802483T2 (enExample)
TW (1) TW550076B (enExample)
UA (1) UA50772C2 (enExample)
WO (1) WO1997045124A1 (enExample)
ZA (1) ZA974735B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102406606A (zh) * 2011-11-29 2012-04-11 海南美大制药有限公司 富马酸喹硫平脂质体固体制剂

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9922271D0 (en) 1999-09-21 1999-11-17 Zeneca Ltd Formulation
SE0003126D0 (sv) * 2000-09-05 2000-09-05 Astrazeneca Ab Method of treatment
US7067148B2 (en) 2001-02-15 2006-06-27 King Pharmaceutical Research & Development, Inc. Stabilized pharmaceutical and thyroid hormone compositions and method of preparation
US20030068375A1 (en) 2001-08-06 2003-04-10 Curtis Wright Pharmaceutical formulation containing gelling agent
US7101569B2 (en) 2001-08-14 2006-09-05 Franz G Andrew Methods of administering levothyroxine pharmaceutical compositions
SE0102855D0 (sv) * 2001-08-27 2001-08-27 Astrazeneca Ab Method of treatment
WO2003039516A1 (en) * 2001-11-07 2003-05-15 Fujisawa Pharmaceuticla Co., Ltd. Method for improving dissolution of poorly dispersible medicaments
TW200735878A (en) * 2005-11-18 2007-10-01 Astrazeneca Ab Pharmaceutical compositions
US20100178333A1 (en) 2006-01-25 2010-07-15 Astron Research Limited Sustained release dosage form of phenothiazine derivatives containing channelizer
SA07280459B1 (ar) 2006-08-25 2011-07-20 بيورديو فارما إل. بي. أشكال جرعة صيدلانية للتناول عن طريق الفم مقاومة للعبث تشتمل على مسكن شبه أفيوني
GB0618879D0 (en) * 2006-09-26 2006-11-01 Zysis Ltd Pharmaceutical compositions
PT103884A (pt) * 2006-11-17 2008-05-19 Astrazeneca Ab Composições de libertação prolongada e métodos para a sua preparação
ATE480227T1 (de) 2007-02-14 2010-09-15 Lesvi Laboratorios Sl Pharmazeutische zusammensetzungen mit quetiapinfumarat
WO2008110337A2 (en) 2007-03-09 2008-09-18 Synthon B.V. Pharmaceutical composition of quetiapine fumarate
SI2262486T1 (sl) 2008-08-01 2013-04-30 Krka, Tovarna Zdravil, D.D., Novo Mesto Sestavek kvetiapina
EP2153834A3 (en) 2008-08-07 2010-02-24 Farmaprojects, S.A. Extended release pharmaceutical compositions comprising quetiapine salts
DE102008046650A1 (de) 2008-09-10 2010-03-11 Tiefenbacher Pharmachemikalien Alfred E. Tiefenbacher Gmbh & Co. Kg Quetiapin enthaltende Retardtablette
EP2373319B1 (en) * 2009-01-05 2013-07-31 Torrent Pharmaceuticals Limited Sustained release pharmaceutical composition of quetiapine and process for preparation thereof
WO2010089259A2 (en) 2009-02-04 2010-08-12 Woerwag R&D Gmbh Sustained release composition containing quetiapine
EP2233130A1 (en) * 2009-03-23 2010-09-29 Genepharm (Europe) Trading Limited A sustained release oral composition of an antipsychotic agent
AR076907A1 (es) * 2009-05-13 2011-07-20 Wyeth Llc Composiciones con liberacion rapida de farmaco
WO2011132008A2 (en) 2010-04-22 2011-10-27 EGIS Gyűgyszergyár Nyilvánosan Múködő Részvény társaság Controlled release pharmaceutical composition
WO2011154118A1 (en) 2010-06-07 2011-12-15 Alfred E. Tiefenbacher (Gmbh & Co. Kg) Quetiapine prolonged-release tablets
DE102010033527A1 (de) 2010-08-05 2012-02-09 Acino Pharma Ag Quetiapin-Tabletten
TR201008261A1 (tr) 2010-10-08 2012-04-24 Sanovel İlaç San. Ve Ti̇c. A.Ş. Kontrollü salım gerçekleştiren ketiapin formülasyonları
CN102218042A (zh) * 2011-05-26 2011-10-19 青岛黄海制药有限责任公司 富马酸喹硫平组合物的缓释片剂及其制备方法
DE102011115690A1 (de) 2011-10-11 2013-04-11 Acino Pharma Ag Quetiapin enthaltende Formulierungen
US20150231080A1 (en) 2012-09-10 2015-08-20 Pharmathen S.A. Pharmaceutical composition comprising an atypical antipsychotic agent and method for the preparation thereof
EP2848244A1 (en) 2013-09-16 2015-03-18 Yildiz Özsoy Erginer Extended release tablet formulations of quetiapine
AU2016278846B2 (en) * 2015-06-19 2021-08-05 Biotie Therapies, Inc. Controlled-release tozadenant formulations
CN106187873B (zh) * 2016-07-25 2019-11-05 宜春学院 一种芳胺基烷基氧类化合物及其制备方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8607684D0 (en) * 1986-03-27 1986-04-30 Ici America Inc Thiazepine compounds
US4775535A (en) * 1986-04-04 1988-10-04 Hans Lowey Method of preparing controlled long-acting pharmaceutical formulations in unit dosage form having uniform and comparable bioavailability characteristics
US4756911A (en) * 1986-04-16 1988-07-12 E. R. Squibb & Sons, Inc. Controlled release formulation
EP0266707B1 (en) * 1986-11-03 1992-01-22 Schering Corporation Sustained release labetalol tablet
IE59540B1 (en) * 1987-01-09 1994-03-09 Elan Corp Sustained release capsule or tablet formulation
GB8705574D0 (en) * 1987-03-10 1987-04-15 Ici Plc Preparation of thiazepine compound
US4983398A (en) * 1987-12-21 1991-01-08 Forest Laboratories, Inc. Sustained release drug dosage forms containing hydroxypropylmethylcellulose and alkali metal carboxylates
IL92966A (en) * 1989-01-12 1995-07-31 Pfizer Dispensing devices powered by hydrogel
SE9003902D0 (sv) * 1990-12-07 1990-12-07 Astra Ab Solid dosage forms of a drug
IT1256651B (it) * 1992-12-11 1995-12-12 Giancarlo Santus Composizione farmaceutica a rilascio controllato in sospensione liquida
JP3116970B2 (ja) * 1991-06-12 2000-12-11 三菱東京製薬株式会社 ペミロラストカリウムの徐放性製剤
IT1256393B (it) * 1992-11-17 1995-12-04 Inverni Della Beffa Spa Forme matriciali multistrato per il rilascio controllato di principi attivi
US5393765A (en) * 1993-12-13 1995-02-28 Hoffmann-La Roche Inc. Pharmaceutical compositions with constant erosion volume for zero order controlled release
JPH10500412A (ja) * 1994-05-13 1998-01-13 スミスクライン・ビーチャム・コーポレイション カルシウム摂取を増加させるための方法および組成物

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102406606A (zh) * 2011-11-29 2012-04-11 海南美大制药有限公司 富马酸喹硫平脂质体固体制剂

Also Published As

Publication number Publication date
EP0907364B1 (en) 2002-08-14
JP5888549B2 (ja) 2016-03-22
UA50772C2 (uk) 2002-11-15
JP2014167026A (ja) 2014-09-11
HRP970299B1 (en) 2001-12-31
HUP9902194A3 (en) 2000-03-28
TW550076B (en) 2003-09-01
CN1142780C (zh) 2004-03-24
SK163998A3 (en) 1999-05-07
SK284131B6 (sk) 2004-09-08
AU2967597A (en) 1998-01-05
CA2251944C (en) 2007-04-10
IL127222A (en) 2001-03-19
JP2000511170A (ja) 2000-08-29
EG24118A (en) 2008-07-06
CZ388098A3 (cs) 1999-02-17
JP2012031206A (ja) 2012-02-16
PL189887B1 (pl) 2005-10-31
ZA974735B (en) 1997-12-01
NZ332198A (en) 2000-05-26
NO985539L (no) 1998-11-27
CZ293760B6 (cs) 2004-07-14
WO1997045124A1 (en) 1997-12-04
CA2251944A1 (en) 1997-12-04
DE69714739D1 (de) 2002-09-19
DK0907364T3 (da) 2002-11-11
GB9709761D0 (en) 1997-07-09
AR003662A1 (es) 1998-09-09
EP0907364A1 (en) 1999-04-14
CN1511532A (zh) 2004-07-14
NO327801B1 (no) 2009-09-28
ID18352A (id) 1998-04-02
AU727219B2 (en) 2000-12-07
HUP9902194A2 (hu) 2000-02-28
DE69714739T2 (de) 2003-05-15
IL127222A0 (en) 2000-06-01
TR199802483T2 (xx) 1999-02-22
HRP970299A2 (en) 1998-04-30
HU225152B1 (en) 2006-07-28
BR9709271A (pt) 1999-08-10
MY120120A (en) 2005-09-30
ATE222105T1 (de) 2002-08-15
NO985539D0 (no) 1998-11-27
GB9611328D0 (en) 1996-08-07
JP2006152006A (ja) 2006-06-15
CN1219879A (zh) 1999-06-16
JP2007119495A (ja) 2007-05-17
PL330223A1 (en) 1999-05-10
PT907364E (pt) 2002-12-31
SI0907364T1 (en) 2003-02-28
ES2182079T3 (es) 2003-03-01
RU2201754C2 (ru) 2003-04-10

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