CN100569228C - 用于治疗癌症的脂肪酸类似物 - Google Patents

用于治疗癌症的脂肪酸类似物 Download PDF

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Publication number
CN100569228C
CN100569228C CNB018127177A CN01812717A CN100569228C CN 100569228 C CN100569228 C CN 100569228C CN B018127177 A CNB018127177 A CN B018127177A CN 01812717 A CN01812717 A CN 01812717A CN 100569228 C CN100569228 C CN 100569228C
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CN
China
Prior art keywords
cell
tumor
cancer
alkyl
fatty acid
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Expired - Fee Related
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CNB018127177A
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English (en)
Chinese (zh)
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CN1441671A (zh
Inventor
R·伯奇
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Thia Medica AS
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Thia Medica AS
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Publication of CN1441671A publication Critical patent/CN1441671A/zh
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Publication of CN100569228C publication Critical patent/CN100569228C/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/255—Esters, e.g. nitroglycerine, selenocyanates of sulfoxy acids or sulfur analogues thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CNB018127177A 2000-07-13 2001-07-13 用于治疗癌症的脂肪酸类似物 Expired - Fee Related CN100569228C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NO20003591A NO20003591L (no) 2000-07-13 2000-07-13 Fettsyreanaloger for behandling av kreft
NO20003591 2000-07-13

Publications (2)

Publication Number Publication Date
CN1441671A CN1441671A (zh) 2003-09-10
CN100569228C true CN100569228C (zh) 2009-12-16

Family

ID=19911376

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB018127177A Expired - Fee Related CN100569228C (zh) 2000-07-13 2001-07-13 用于治疗癌症的脂肪酸类似物

Country Status (17)

Country Link
US (1) US7378443B2 (enExample)
EP (1) EP1313463B1 (enExample)
JP (1) JP2004502732A (enExample)
KR (2) KR100861428B1 (enExample)
CN (1) CN100569228C (enExample)
AT (1) ATE320802T1 (enExample)
AU (2) AU7286001A (enExample)
BR (1) BR0112399A (enExample)
CA (1) CA2414480A1 (enExample)
DE (1) DE60118198T2 (enExample)
ES (1) ES2261441T3 (enExample)
MX (1) MXPA02012944A (enExample)
NO (2) NO20003591L (enExample)
NZ (1) NZ523316A (enExample)
RU (1) RU2283105C2 (enExample)
WO (1) WO2002003983A1 (enExample)
ZA (1) ZA200210028B (enExample)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO328803B1 (no) 2000-03-03 2010-05-18 Thia Medica Nye fettsyreanaloger
AU2003278602C1 (en) 2002-06-20 2010-08-12 Pronova Biopharma Norge As Sulfur-containing phospholipid derivatives
JP2008506773A (ja) 2004-07-19 2008-03-06 ティア メディカ アクスイェ セルスカプ タンパク質材料と非酸化性脂肪酸体を含む組成物
NO20053519L (no) * 2005-07-18 2007-01-19 Thia Medica As Anvendelse av forbindelser som omfatter fettsyrer
US8986253B2 (en) 2008-01-25 2015-03-24 Tandem Diabetes Care, Inc. Two chamber pumps and related methods
US8408421B2 (en) 2008-09-16 2013-04-02 Tandem Diabetes Care, Inc. Flow regulating stopcocks and related methods
EP2334234A4 (en) 2008-09-19 2013-03-20 Tandem Diabetes Care Inc DEVICE FOR MEASURING THE CONCENTRATION OF A SOLVED SUBSTANCE AND CORRESPONDING METHOD
US8758323B2 (en) 2009-07-30 2014-06-24 Tandem Diabetes Care, Inc. Infusion pump system with disposable cartridge having pressure venting and pressure feedback
US9180242B2 (en) 2012-05-17 2015-11-10 Tandem Diabetes Care, Inc. Methods and devices for multiple fluid transfer
US9555186B2 (en) 2012-06-05 2017-01-31 Tandem Diabetes Care, Inc. Infusion pump system with disposable cartridge having pressure venting and pressure feedback
AU2014228387B2 (en) 2013-03-11 2016-09-01 Sciadonics, Inc. Lipid compositions containing bioactive fatty acids
WO2014140934A2 (en) 2013-03-11 2014-09-18 Life Science Nutrition As Natural lipids containing non-oxidizable fatty acids
US9173998B2 (en) 2013-03-14 2015-11-03 Tandem Diabetes Care, Inc. System and method for detecting occlusions in an infusion pump
DE102014116958B9 (de) * 2014-11-19 2017-10-05 Trumpf Laser- Und Systemtechnik Gmbh Optisches System zur Strahlformung eines Laserstrahls, Laserbearbeitungsanlage, Verfahren zur Materialbearbeitung und Verwenden einer gemeinsamen langgezogenen Fokuszone zur Lasermaterialbearbeitung
KR20180027516A (ko) * 2015-06-11 2018-03-14 유니버시티 오브 마이애미 암 치료 및 진단
CN105498622B (zh) * 2015-12-10 2017-10-17 江南大学 一种含硒表面活性剂及其制备方法和应用
CN107235880B (zh) * 2017-06-30 2018-10-30 江南大学 一种含硒阳离子表面活性剂及其应用
GB201910644D0 (en) * 2019-07-25 2019-09-11 Coegin Pharma As Cancer Treatment
AU2020405068A1 (en) 2019-12-18 2022-07-07 Stinginn Llc Substituted 1,2, 4-triazoles and methods of use
US11897888B1 (en) 2020-04-30 2024-02-13 Stinginn Llc Small molecular inhibitors of sting signaling compositions and methods of use
CN115260964A (zh) * 2022-08-29 2022-11-01 烟台市福山义昌精细化工厂 一种石油油管丝扣专用密封胶及其制备方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6046237A (en) * 1995-07-14 2000-04-04 Berge; Rolf Non-β-oxidizable fatty acid analogues, their uses as therapeutic active medicaments

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0686377B2 (ja) * 1985-09-30 1994-11-02 日清製粉株式会社 がん転移抑制剤
SE9103572D0 (sv) * 1991-11-29 1991-11-29 Astra Ab Organic salts of n,n'-diacetyl cystine
JPH0797320A (ja) * 1993-08-04 1995-04-11 Takuma Sasaki 制癌剤
US6358915B1 (en) * 1995-03-07 2002-03-19 George Washington University Methods for inhibiting metastasis
AU693682B2 (en) * 1995-04-10 1998-07-02 Taiho Pharmaceutical Co., Ltd. Cancerous metastasis inhibitor
DE69726182T2 (de) * 1996-12-11 2004-08-12 Dana-Farber Cancer Institute, Inc., Boston Methoden und pharmazeutische zusammenstellungen zur wachstumsverhinderung von tumorzellen enthaltend einen ppar-gamma agonisten und einen map kinase inhibitor
DE19700774A1 (de) * 1997-01-13 1998-07-16 Hoechst Ag Antiadhäsive Sulfatid-Mimetika
WO1999058120A1 (en) * 1998-05-08 1999-11-18 Rolf Berge USE OF NON-β-OXIDIZABLE FATTY ACID ANALOGUES FOR TREATMENT OF SYNDROME-X CONDITIONS
JP4993878B2 (ja) * 2005-06-28 2012-08-08 ダイキョーニシカワ株式会社 多気筒エンジンの吸気装置

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6046237A (en) * 1995-07-14 2000-04-04 Berge; Rolf Non-β-oxidizable fatty acid analogues, their uses as therapeutic active medicaments

Also Published As

Publication number Publication date
NZ523316A (en) 2004-09-24
ATE320802T1 (de) 2006-04-15
DE60118198T2 (de) 2007-01-25
BR0112399A (pt) 2003-05-27
KR20030016399A (ko) 2003-02-26
NO324634B1 (no) 2007-11-26
WO2002003983A1 (en) 2002-01-17
US7378443B2 (en) 2008-05-27
CN1441671A (zh) 2003-09-10
JP2004502732A (ja) 2004-01-29
ZA200210028B (en) 2004-01-26
MXPA02012944A (es) 2004-05-17
NO20003591L (no) 2002-01-14
US20040024063A1 (en) 2004-02-05
AU7286001A (en) 2002-01-21
CA2414480A1 (en) 2002-01-17
DE60118198D1 (de) 2006-05-11
ES2261441T3 (es) 2006-11-16
KR100861428B1 (ko) 2008-10-02
RU2283105C2 (ru) 2006-09-10
NO20025930L (no) 2003-01-13
AU2001272860B2 (en) 2005-11-24
NO20003591D0 (no) 2000-07-13
NO20025930D0 (no) 2002-12-11
EP1313463A1 (en) 2003-05-28
KR20080071598A (ko) 2008-08-04
HK1057473A1 (zh) 2004-04-08
EP1313463B1 (en) 2006-03-22

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