CN100400534C - 醛糖还原酶抑制剂,其制备方法和用途 - Google Patents
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- CN100400534C CN100400534C CNB031466516A CN03146651A CN100400534C CN 100400534 C CN100400534 C CN 100400534C CN B031466516 A CNB031466516 A CN B031466516A CN 03146651 A CN03146651 A CN 03146651A CN 100400534 C CN100400534 C CN 100400534C
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- 210000001625 seminal vesicle Anatomy 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000001632 sodium acetate Substances 0.000 description 1
- 229960004249 sodium acetate Drugs 0.000 description 1
- 235000017281 sodium acetate Nutrition 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 229940039790 sodium oxalate Drugs 0.000 description 1
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- 238000003756 stirring Methods 0.000 description 1
- 239000006190 sub-lingual tablet Substances 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 238000010254 subcutaneous injection Methods 0.000 description 1
- 229940098466 sublingual tablet Drugs 0.000 description 1
- 125000001424 substituent group Chemical group 0.000 description 1
- 229960005137 succinic acid Drugs 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 235000000346 sugar Nutrition 0.000 description 1
- 239000000829 suppository Substances 0.000 description 1
- 230000009747 swallowing Effects 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- 229960001367 tartaric acid Drugs 0.000 description 1
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- ILMRJRBKQSSXGY-UHFFFAOYSA-N tert-butyl(dimethyl)silicon Chemical group C[Si](C)C(C)(C)C ILMRJRBKQSSXGY-UHFFFAOYSA-N 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 description 1
- 125000001544 thienyl group Chemical group 0.000 description 1
- 229960005371 tolbutamide Drugs 0.000 description 1
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 description 1
- 208000035408 type 1 diabetes mellitus 1 Diseases 0.000 description 1
- 201000010653 vesiculitis Diseases 0.000 description 1
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- 235000010447 xylitol Nutrition 0.000 description 1
- 229960003487 xylose Drugs 0.000 description 1
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Images
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
培养基 | 气生菌丝 | 基内菌丝 | 可溶性色素 |
察氏琼脂 | 浅棕灰色 | 浅灰棕色 | 无 |
甘油-天门冬酰胺琼脂(ISP5) | 浅灰棕色 | 灰色 | 无 |
无机盐淀粉琼脂(ISP4) | 浅棕灰色 | 浅灰棕色 | 无 |
燕麦片琼脂(ISP3) | 浅灰黄棕色 | 浅棕灰色 | 无 |
酵母膏-麦芽膏琼脂(ISP2) | 灰黄棕色 | 深黄棕色 | 无 |
马铃薯浸汁琼脂 | 浅棕灰色 | 灰棕色 | 无 |
生理生化 | N99-596 | 碳源利用 | N99-596 |
明胶液化 | + | 葡萄糖 | + |
牛奶凝固 | + | 阿拉伯糖 | + |
牛奶胨化 | - | 甜醇 | + |
淀粉水解 | - | 蔗糖 | + |
硝酸盐还原 | + | 甘油 | + |
硫化氢产生 | - | 果糖 | + |
黑色素生成 | - | 半乳糖 | + |
纤维素生长 | - | 麦芽糖 | + |
脲的利用 | + | 甘露糖 | + |
棉子糖 | + | ||
抗菌谱 | 木糖 | + | |
E.coli | - | 山梨醇 | + |
B.subtilis | - | 草酸钠 | + |
Candida albicans | - | 醋酸钠 | + |
Aspergillus niger | - | 密二糖 | + |
学名 | 株 | 编号 |
Streptomyces sp | N99-596 | |
Streptomyces argenteolus | JCM4623 | AB045872 |
Streptomyces ornatus | DSM40307 | X79326 |
Streptomyces caviscabies | ATCC51928 | AF112160 |
Streptomyces setonii | ATCC25497 | D63872 |
Streptomyces avermitilis | NCIBM 12804T | AF145223 |
Streptomyces virginiae | IFO 3729 | D85119 |
Streptomyces lavendulae | IFO 12341 | D85110 |
Streptomyces cyaneus | NRRL B-2296 | AF346475 |
Streptomyces indigocolor | NRRL B-12336 | AF346474 |
Streptomyces mirabilis | ATCC27447 | AF112180 |
Streptosporangium roseum | DSM43021 | X89947 |
培养基 | 气生菌丝 | 基内菌丝 | 可溶性色素 |
察氏琼脂 | 浅棕灰色 | 浅灰棕色 | 无 |
甘油-天门冬酰胺琼脂(ISP5) | 浅灰棕色 | 灰色 | 无 |
无机盐淀粉琼脂(ISP4) | 浅棕灰色 | 浅灰棕色 | 无 |
燕麦片琼脂(ISP3) | 棕灰色 | 浅棕灰色 | 无 |
酵母膏-麦芽膏琼脂(ISP2) | 棕灰色 | 深黄棕色 | 无 |
马铃薯浸汁琼脂 | 浅棕灰色 | 灰棕色 | 无 |
学名 | 株 | 编号 |
Streptomyces Sp. | N99-253 | |
Streptomyces argenteolus | JCM4623T | AB045872 |
Streptomyces flavogriseus | CBS 101.34=DSM 40323T | AJ494864 |
Streptomyces caviscabies | ATCC51928T | AF112160 |
Streptomyces setonii | ATCC25497T | D63872 |
Streptomyces ornatus | DSM40307T | X79326 |
Streptomyces cyaneus | ISP 5108T | A0899460 |
Streptomyces venezuelae | JCM 4526T | AB045890 |
Streptomyces galilaeus | JCM 4757T | AB045878 |
Streptomyces bobili | JCM 4624T | AB045846 |
Claims (11)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CNB031466516A CN100400534C (zh) | 2003-07-10 | 2003-07-10 | 醛糖还原酶抑制剂,其制备方法和用途 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CNB031466516A CN100400534C (zh) | 2003-07-10 | 2003-07-10 | 醛糖还原酶抑制剂,其制备方法和用途 |
Publications (2)
Publication Number | Publication Date |
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CN1566109A CN1566109A (zh) | 2005-01-19 |
CN100400534C true CN100400534C (zh) | 2008-07-09 |
Family
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CNB031466516A Expired - Fee Related CN100400534C (zh) | 2003-07-10 | 2003-07-10 | 醛糖还原酶抑制剂,其制备方法和用途 |
Country Status (1)
Country | Link |
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CN (1) | CN100400534C (zh) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20100286030A1 (en) * | 2007-10-05 | 2010-11-11 | The University Of Alabama | novel bacteriocin from a new streptomyces species |
WO2012016140A2 (en) | 2010-07-30 | 2012-02-02 | Bioworks, Inc. | Growth enhancement and control of bacterial and fungal plant diseases with streptomyces scopuliridis |
CN107019702A (zh) * | 2016-01-31 | 2017-08-08 | 复旦大学附属华山医院 | 烟酰胺腺嘌呤二核苷酸磷酸在制备防治糖尿病肾病药物中的用途 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH06321752A (ja) * | 1993-05-07 | 1994-11-22 | Kao Corp | 美白剤 |
JPH08165237A (ja) * | 1994-12-12 | 1996-06-25 | Bio Kosumosu:Kk | 血液流動性改善剤 |
-
2003
- 2003-07-10 CN CNB031466516A patent/CN100400534C/zh not_active Expired - Fee Related
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH06321752A (ja) * | 1993-05-07 | 1994-11-22 | Kao Corp | 美白剤 |
JPH08165237A (ja) * | 1994-12-12 | 1996-06-25 | Bio Kosumosu:Kk | 血液流動性改善剤 |
Non-Patent Citations (2)
Title |
---|
木犀草素和奥洛波尔的合成. 戈夏等.中国医药工业杂志,第34卷第4期. 2003 |
木犀草素和奥洛波尔的合成. 戈夏等.中国医药工业杂志,第34卷第4期. 2003 * |
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