CN100398521C - 作为金属蛋白酶mmp12抑制剂的2,5-二氧代咪唑烷-4-基乙酰胺及类似物 - Google Patents

作为金属蛋白酶mmp12抑制剂的2,5-二氧代咪唑烷-4-基乙酰胺及类似物 Download PDF

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CN100398521C
CN100398521C CNB038237970A CN03823797A CN100398521C CN 100398521 C CN100398521 C CN 100398521C CN B038237970 A CNB038237970 A CN B038237970A CN 03823797 A CN03823797 A CN 03823797A CN 100398521 C CN100398521 C CN 100398521C
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ethanamide
alkyl imidazole
dioxo alkyl
phenyl
methyl
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CN1688550A (zh
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克里斯特·亨里克森
马格努斯·芒克阿弗罗森舍尔德
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AstraZeneca AB
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AstraZeneca AB
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    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72—Two oxygen atoms, e.g. hydantoin
    • C07D233/76—Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom
    • C07D233/78—Radicals substituted by oxygen atoms
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CNB038237970A 2002-08-27 2003-08-26 作为金属蛋白酶mmp12抑制剂的2,5-二氧代咪唑烷-4-基乙酰胺及类似物 Expired - Fee Related CN100398521C (zh)

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SE02025393 2002-08-27
SE0202539A SE0202539D0 (sv) 2002-08-27 2002-08-27 Compounds

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CN1688550A CN1688550A (zh) 2005-10-26
CN100398521C true CN100398521C (zh) 2008-07-02

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US (2) US7354940B2 (https=)
EP (1) EP1542977B1 (https=)
JP (1) JP2006503019A (https=)
KR (1) KR20050059093A (https=)
CN (1) CN100398521C (https=)
AR (1) AR041066A1 (https=)
AT (1) ATE348816T1 (https=)
AU (1) AU2003253557B2 (https=)
BR (1) BR0313635A (https=)
CA (1) CA2495853A1 (https=)
CY (1) CY1106027T1 (https=)
DE (1) DE60310582T2 (https=)
DK (1) DK1542977T3 (https=)
ES (1) ES2277143T3 (https=)
IL (1) IL166826A (https=)
IS (1) IS2415B (https=)
MX (1) MXPA05002066A (https=)
MY (1) MY137562A (https=)
NO (1) NO20051540L (https=)
NZ (1) NZ538443A (https=)
PL (1) PL375754A1 (https=)
PT (1) PT1542977E (https=)
RU (1) RU2326117C2 (https=)
SE (1) SE0202539D0 (https=)
TW (1) TWI332500B (https=)
UA (1) UA81635C2 (https=)
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