CN100384473C - 油佐剂疫苗 - Google Patents

油佐剂疫苗 Download PDF

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Publication number
CN100384473C
CN100384473C CNB001374818A CN00137481A CN100384473C CN 100384473 C CN100384473 C CN 100384473C CN B001374818 A CNB001374818 A CN B001374818A CN 00137481 A CN00137481 A CN 00137481A CN 100384473 C CN100384473 C CN 100384473C
Authority
CN
China
Prior art keywords
oil
vaccine
aqueous phase
emulsifier
oil adjuvant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CNB001374818A
Other languages
English (en)
Chinese (zh)
Other versions
CN1307903A (zh
Inventor
斋藤晃一
岸本洋子
宫原德治
高濑公三
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chemo Sero Therapeutic Research Institute Kaketsuken
NOF Corp
Original Assignee
Chemo Sero Therapeutic Research Institute Kaketsuken
NOF Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemo Sero Therapeutic Research Institute Kaketsuken, NOF Corp filed Critical Chemo Sero Therapeutic Research Institute Kaketsuken
Publication of CN1307903A publication Critical patent/CN1307903A/zh
Application granted granted Critical
Publication of CN100384473C publication Critical patent/CN100384473C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/113—Multiple emulsions, e.g. oil-in-water-in-oil

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CNB001374818A 1999-11-05 2000-11-05 油佐剂疫苗 Expired - Fee Related CN100384473C (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP31612199A JP2001131087A (ja) 1999-11-05 1999-11-05 オイルアジュバントワクチン
JP316121/99 1999-11-05
JP316121/1999 1999-11-05

Publications (2)

Publication Number Publication Date
CN1307903A CN1307903A (zh) 2001-08-15
CN100384473C true CN100384473C (zh) 2008-04-30

Family

ID=18073491

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB001374818A Expired - Fee Related CN100384473C (zh) 1999-11-05 2000-11-05 油佐剂疫苗

Country Status (10)

Country Link
US (1) US20050158330A1 (https=)
EP (1) EP1097721B1 (https=)
JP (1) JP2001131087A (https=)
KR (1) KR100726818B1 (https=)
CN (1) CN100384473C (https=)
AU (1) AU780054B2 (https=)
DE (1) DE60002650T2 (https=)
DK (1) DK1097721T3 (https=)
ES (1) ES2199734T3 (https=)
TW (1) TW581682B (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102580082A (zh) * 2012-02-28 2012-07-18 肇庆大华农生物药品有限公司 一种禽用灭活疫苗及其制备方法

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1245608B1 (en) * 2001-03-27 2004-05-19 Nof Corporation Polyethylene glycol and process for producing the same
FR2824279B1 (fr) * 2001-05-04 2004-05-28 Seppic Sa Emulsion e/h concentree
US6676958B2 (en) 2001-06-19 2004-01-13 Advanced Bioadjuvants, Llc Adjuvant composition for mucosal and injection delivered vaccines
WO2003000291A1 (fr) * 2001-06-22 2003-01-03 Techno Network Shikoku Co., Ltd. Vesicules lipidiques, processus de production de vesicules lipidiques et procede d'immobilisation de gene sur ces vesicules lipidiques
FR2824269B1 (fr) * 2001-09-03 2012-03-02 Seppic Sa Composition adjuvante constituee de 1% a 15% de tensioactifs a hlb global compris entre 5 et 8 et de 85% a 99% de corps gras
TWI350174B (en) * 2003-03-12 2011-10-11 Wyeth Corp Adjuvanted bovine vaccines
GB2421908A (en) * 2004-12-23 2006-07-12 Univ College London Hospitals Medicament for treatment of inflammatory diseases
WO2006078059A1 (ja) 2005-01-19 2006-07-27 Dainippon Sumitomo Pharma Co., Ltd. 希釈用乳化組成物および癌ワクチン組成物
GB2442408B (en) 2005-04-25 2010-06-30 Cadila Pharmaceuticals Ltd Mycobacterium W as an adjuvant
EP2172263A4 (en) * 2007-07-02 2015-08-05 Nisshin Oillio Group Ltd E / H / E EMULSION COMPOSITION
US8010465B2 (en) * 2008-02-26 2011-08-30 Microsoft Corporation Predicting candidates using input scopes
CN101721694B (zh) * 2009-11-07 2013-01-30 中国农业科学院兰州兽医研究所 山羊支原体肺炎二联灭活疫苗及其制备方法
EP3351114A1 (en) * 2012-01-31 2018-07-25 Benemilk Ltd Animal feed and a process for its preparation
CN103223164B (zh) * 2013-04-15 2014-08-20 华南农业大学 一种水包油包水型佐剂疫苗及其制备方法
US20150359880A1 (en) * 2014-06-16 2015-12-17 Biomune Company Dual adjuvant vaccine compositions, preparation and uses
CN104398478B (zh) * 2014-11-03 2017-05-10 江苏省农业科学院 兽用药物的复乳型载体及其应用
CA3056197A1 (en) * 2017-03-15 2018-09-20 Vivavax Inc. Biocompatible and biodegradable emulsions and compositions, and methods of use thereof
JP2019001770A (ja) * 2017-06-15 2019-01-10 エス・ピー・ジーテクノ株式会社 乳化型ワクチン製剤とその生成用デバイス
CN112843227B (zh) * 2017-09-19 2024-05-07 洛阳赛威生物科技有限公司 一种w/o/w佐剂组合物、制备的疫苗组合物及其制备方法
CN107595774B (zh) * 2017-10-24 2020-01-31 湖北医药学院 一种自乳化纳米复乳及其制备方法和应用
CN108578688B (zh) * 2018-04-03 2022-02-11 武汉轻工大学 多重纳米乳疫苗佐剂的制备方法
CN110585439B (zh) * 2019-09-30 2023-06-09 长春生物制品研究所有限责任公司 一种改良型的冻干甲型肝炎减毒活疫苗稳定剂、疫苗半成品、疫苗成品及其制备方法
CN113546162B (zh) * 2021-05-31 2023-07-18 江苏省农业科学院 一种支原体疫苗及其制备方法
CN113940994B (zh) * 2021-11-09 2023-09-15 南华大学 壳聚糖-Pickering乳液白细胞介素12佐剂体系的制备方法及其应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11106351A (ja) * 1997-10-02 1999-04-20 Chemo Sero Therapeut Res Inst オイルアジュバントワクチンおよびその製造方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2649012B1 (fr) * 1989-07-03 1991-10-25 Seppic Sa Emulsions multiphasiques injectables
FR2649013B1 (fr) * 1989-07-03 1991-10-25 Seppic Sa Vaccins et vecteurs de principes actifs fluides contenant une huile metabolisable
US5622649A (en) * 1991-06-27 1997-04-22 Emory University Multiple emulsions and methods of preparation
EP0781559B1 (en) * 1995-11-30 2007-02-07 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute Oil adjuvant vaccine and method for preparing same
US20060003012A9 (en) * 2001-09-26 2006-01-05 Sean Brynjelsen Preparation of submicron solid particle suspensions by sonication of multiphase systems

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11106351A (ja) * 1997-10-02 1999-04-20 Chemo Sero Therapeut Res Inst オイルアジュバントワクチンおよびその製造方法

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102580082A (zh) * 2012-02-28 2012-07-18 肇庆大华农生物药品有限公司 一种禽用灭活疫苗及其制备方法
CN102580082B (zh) * 2012-02-28 2014-12-10 肇庆大华农生物药品有限公司 一种禽用灭活疫苗及其制备方法

Also Published As

Publication number Publication date
EP1097721A3 (en) 2001-05-23
DE60002650D1 (de) 2003-06-18
JP2001131087A (ja) 2001-05-15
CN1307903A (zh) 2001-08-15
DE60002650T2 (de) 2004-03-11
TW581682B (en) 2004-04-01
AU780054B2 (en) 2005-02-24
EP1097721B1 (en) 2003-05-14
KR100726818B1 (ko) 2007-06-12
KR20010051463A (ko) 2001-06-25
ES2199734T3 (es) 2004-03-01
DK1097721T3 (da) 2003-09-01
EP1097721A2 (en) 2001-05-09
US20050158330A1 (en) 2005-07-21
AU6971300A (en) 2001-05-10

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C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
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GR01 Patent grant
C17 Cessation of patent right
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20080430

Termination date: 20091207