CL2023003564A1 - Inhibidores de la tirosina quinasa de bruton y métodos para su uso - Google Patents

Inhibidores de la tirosina quinasa de bruton y métodos para su uso

Info

Publication number
CL2023003564A1
CL2023003564A1 CL2023003564A CL2023003564A CL2023003564A1 CL 2023003564 A1 CL2023003564 A1 CL 2023003564A1 CL 2023003564 A CL2023003564 A CL 2023003564A CL 2023003564 A CL2023003564 A CL 2023003564A CL 2023003564 A1 CL2023003564 A1 CL 2023003564A1
Authority
CL
Chile
Prior art keywords
methods
tyrosine kinase
kinase inhibitors
bruton tyrosine
bruton
Prior art date
Application number
CL2023003564A
Other languages
English (en)
Spanish (es)
Inventor
Balasubramanian Sriram
Cornelissen Ivo
Guo Yue
H Leu Jocelyn
E Packman Kathryn
Alexander Palmer James
Philippar Ulrike
Rao Navin
S Tichenor Mark
D Venable Jennifer
J M Wiener John
Miao Xin
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of CL2023003564A1 publication Critical patent/CL2023003564A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/63Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/675Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CL2023003564A 2021-06-04 2023-11-29 Inhibidores de la tirosina quinasa de bruton y métodos para su uso CL2023003564A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US202163196843P 2021-06-04 2021-06-04

Publications (1)

Publication Number Publication Date
CL2023003564A1 true CL2023003564A1 (es) 2024-06-21

Family

ID=82214195

Family Applications (2)

Application Number Title Priority Date Filing Date
CL2023003564A CL2023003564A1 (es) 2021-06-04 2023-11-29 Inhibidores de la tirosina quinasa de bruton y métodos para su uso
CL2024002895A CL2024002895A1 (es) 2021-06-04 2024-09-26 Inhibidores de la tirosina quinasa de bruton y métodos de su uso.

Family Applications After (1)

Application Number Title Priority Date Filing Date
CL2024002895A CL2024002895A1 (es) 2021-06-04 2024-09-26 Inhibidores de la tirosina quinasa de bruton y métodos de su uso.

Country Status (14)

Country Link
US (1) US20230013755A1 (https=)
EP (1) EP4346834A1 (https=)
JP (1) JP2024520630A (https=)
KR (1) KR20240019214A (https=)
CN (1) CN117412753A (https=)
AU (1) AU2022284369A1 (https=)
BR (1) BR112023025459A2 (https=)
CA (1) CA3220015A1 (https=)
CL (2) CL2023003564A1 (https=)
IL (1) IL308951A (https=)
JO (1) JOP20230310A1 (https=)
MX (1) MX2023014435A (https=)
TW (1) TW202317127A (https=)
WO (1) WO2022254371A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11964976B1 (en) 2023-09-12 2024-04-23 King Faisal University Substituted pyrido[3′,4′:4,5]pyrrolo[3,2-c][1,6]naphthyridines as CK2 inhibitors
US20250333398A1 (en) 2024-04-30 2025-10-30 Boehringer Ingelheim International Gmbh Monoaryl and hetaryl substituted indazoles and benzimidazoles as sting antagonists and the use thereof as medicament
WO2025228902A1 (en) 2024-04-30 2025-11-06 Boehringer Ingelheim International Gmbh Heterocyclic acids as sting antagonists and the use thereof as medicament
WO2025228899A1 (en) 2024-04-30 2025-11-06 Boehringer Ingelheim International Gmbh Further heterocyclic compounds as sting antagonists and the use thereof as medicament
WO2025228900A1 (en) 2024-04-30 2025-11-06 Boehringer Ingelheim International Gmbh Arylamide substituted indazoles and the use thereof as medicament
WO2025228895A1 (en) 2024-04-30 2025-11-06 Boehringer Ingelheim International Gmbh Hetaryl substituted indazoles and benzimidazoles as sting antagonists and the use thereof as medicament
WO2025228889A1 (en) 2024-04-30 2025-11-06 Boehringer Ingelheim International Gmbh Monoarylic heterocyclic compounds as sting antagonists and the use thereof as medicament

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112015008042A2 (pt) 2012-10-11 2017-07-04 Pharmacyclics Inc diagnósticos complementares para terapia com inibidor de quinase da família tec
MA40596B1 (fr) * 2014-08-11 2021-12-31 Acerta Pharma Bv Combinaisons thérapeutiques d'un inhibiteur de btk et d'un inhibiteur de bcl-2
JO3794B1 (ar) * 2015-12-10 2021-01-31 Janssen Pharmaceutica Nv المركبات متعددة الحلقات كمثبطات لتيروزين كيناز بروتون
WO2018103060A1 (en) * 2016-12-09 2018-06-14 Janssen Pharmaceutica Nv Inhibitors of bruton's tyrosine kinase and methods of their use

Also Published As

Publication number Publication date
AU2022284369A1 (en) 2024-01-25
IL308951A (en) 2024-01-01
EP4346834A1 (en) 2024-04-10
BR112023025459A2 (pt) 2024-02-27
CL2024002895A1 (es) 2025-02-14
CA3220015A1 (en) 2022-12-08
CN117412753A (zh) 2024-01-16
TW202317127A (zh) 2023-05-01
KR20240019214A (ko) 2024-02-14
WO2022254371A1 (en) 2022-12-08
US20230013755A1 (en) 2023-01-19
JOP20230310A1 (ar) 2023-11-29
MX2023014435A (es) 2024-03-08
JP2024520630A (ja) 2024-05-24

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