CL2023001637A1 - Inhibidores de la vía jak1 para el tratamiento del vitíligo. - Google Patents

Inhibidores de la vía jak1 para el tratamiento del vitíligo.

Info

Publication number
CL2023001637A1
CL2023001637A1 CL2023001637A CL2023001637A CL2023001637A1 CL 2023001637 A1 CL2023001637 A1 CL 2023001637A1 CL 2023001637 A CL2023001637 A CL 2023001637A CL 2023001637 A CL2023001637 A CL 2023001637A CL 2023001637 A1 CL2023001637 A1 CL 2023001637A1
Authority
CL
Chile
Prior art keywords
vitiligo
treatment
pathway inhibitors
jak1 pathway
jak1
Prior art date
Application number
CL2023001637A
Other languages
English (en)
Inventor
Michael D Howell
Paul Smith
Kurt Andrew Brown
Fiona Kuo
James Lee
Santos Leandro Luiz Dos
Beth Rumberger
Original Assignee
Incyte Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Corp filed Critical Incyte Corp
Publication of CL2023001637A1 publication Critical patent/CL2023001637A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente descripción se relaciona con inhibidores de la vía JAK1 y su uso para tratar el vitiligo.
CL2023001637A 2020-12-08 2023-06-06 Inhibidores de la vía jak1 para el tratamiento del vitíligo. CL2023001637A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202063122574P 2020-12-08 2020-12-08
US202163246688P 2021-09-21 2021-09-21

Publications (1)

Publication Number Publication Date
CL2023001637A1 true CL2023001637A1 (es) 2023-12-15

Family

ID=79283140

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2023001637A CL2023001637A1 (es) 2020-12-08 2023-06-06 Inhibidores de la vía jak1 para el tratamiento del vitíligo.

Country Status (11)

Country Link
US (1) US11957661B2 (es)
EP (1) EP4259131A1 (es)
JP (1) JP2023552452A (es)
KR (1) KR20230118118A (es)
AU (1) AU2021396231A1 (es)
CA (1) CA3204374A1 (es)
CL (1) CL2023001637A1 (es)
IL (1) IL303238A (es)
MX (1) MX2023006542A (es)
TW (1) TW202237089A (es)
WO (1) WO2022125670A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
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Also Published As

Publication number Publication date
MX2023006542A (es) 2023-08-25
TW202237089A (zh) 2022-10-01
US11957661B2 (en) 2024-04-16
AU2021396231A9 (en) 2024-02-08
JP2023552452A (ja) 2023-12-15
AU2021396231A1 (en) 2023-06-22
CA3204374A1 (en) 2022-06-16
WO2022125670A1 (en) 2022-06-16
EP4259131A1 (en) 2023-10-18
US20220175731A1 (en) 2022-06-09
KR20230118118A (ko) 2023-08-10
IL303238A (en) 2023-07-01

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