CL2023001688A1 - Composiciones y métodos para reducir el mhc clase ii en una célula - Google Patents

Composiciones y métodos para reducir el mhc clase ii en una célula

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Publication number
CL2023001688A1
CL2023001688A1 CL2023001688A CL2023001688A CL2023001688A1 CL 2023001688 A1 CL2023001688 A1 CL 2023001688A1 CL 2023001688 A CL2023001688 A CL 2023001688A CL 2023001688 A CL2023001688 A CL 2023001688A CL 2023001688 A1 CL2023001688 A1 CL 2023001688A1
Authority
CL
Chile
Prior art keywords
cell
compositions
methods
mhc class
reduce mhc
Prior art date
Application number
CL2023001688A
Other languages
English (en)
Spanish (es)
Inventor
Sridhar Srijani
Zhang Yong
Frederick Harrington William
Goel Surbhi
Original Assignee
Intellia Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intellia Therapeutics Inc filed Critical Intellia Therapeutics Inc
Publication of CL2023001688A1 publication Critical patent/CL2023001688A1/es

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    • A61K40/00—Cellular immunotherapy
    • A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/32—T-cell receptors [TCR]
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/15—Natural-killer [NK] cells; Natural-killer T [NKT] cells
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CL2023001688A 2020-12-11 2023-06-09 Composiciones y métodos para reducir el mhc clase ii en una célula CL2023001688A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202063124064P 2020-12-11 2020-12-11
US202063130106P 2020-12-23 2020-12-23

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