MX2019010196A - Composiciones y métodos para la inhibición de proteínas específicas del linaje. - Google Patents

Composiciones y métodos para la inhibición de proteínas específicas del linaje.

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Publication number
MX2019010196A
MX2019010196A MX2019010196A MX2019010196A MX2019010196A MX 2019010196 A MX2019010196 A MX 2019010196A MX 2019010196 A MX2019010196 A MX 2019010196A MX 2019010196 A MX2019010196 A MX 2019010196A MX 2019010196 A MX2019010196 A MX 2019010196A
Authority
MX
Mexico
Prior art keywords
compositions
methods
inhibition
specific proteins
lineage specific
Prior art date
Application number
MX2019010196A
Other languages
English (en)
Inventor
Bolen Joseph
Filip RADOVIC - MORENO Aleksandar
Lydeard John
Original Assignee
Vor Biopharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vor Biopharma Inc filed Critical Vor Biopharma Inc
Publication of MX2019010196A publication Critical patent/MX2019010196A/es

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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70596—Molecules with a "CD"-designation not provided for elsewhere
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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Abstract

Descritos en la presente son composiciones, métodos y kits para su uso en el tratamiento de malignidades hematopoyéticas; las composiciones, métodos y kits comprenden un agente citotóxico que focaliza a células que expresan una proteína de la superficie de la célula específica del linaje y una población de células hematopoyéticas que expresan la proteína de la superficie de la célula específica del linaje, las células hematopoyéticas siendo manipuladas de modo que no se unen al agente citotóxico.
MX2019010196A 2017-02-28 2018-02-28 Composiciones y métodos para la inhibición de proteínas específicas del linaje. MX2019010196A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762464975P 2017-02-28 2017-02-28
PCT/US2018/020327 WO2018160768A1 (en) 2017-02-28 2018-02-28 Compositions and methods for inhibition lineage specific proteins

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MX2019010196A true MX2019010196A (es) 2019-12-19

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US (1) US11975029B2 (es)
EP (1) EP3589291A4 (es)
JP (2) JP7386082B2 (es)
KR (1) KR20190141657A (es)
CN (1) CN110662554A (es)
AU (2) AU2018229351B2 (es)
BR (1) BR112019017751A2 (es)
CA (1) CA3054808A1 (es)
IL (1) IL268895A (es)
MX (1) MX2019010196A (es)
RU (1) RU2019130504A (es)
SG (1) SG11201907870VA (es)
WO (1) WO2018160768A1 (es)

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KR20220047380A (ko) 2019-08-28 2022-04-15 보르 바이오파마 인크. Cll1 변형을 위한 조성물 및 방법
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