CL2022001679A1 - Células de levadura y métodos para la producción de e8,e10-dodecadienil coenzima a, codlemona y derivados - Google Patents

Células de levadura y métodos para la producción de e8,e10-dodecadienil coenzima a, codlemona y derivados

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Publication number
CL2022001679A1
CL2022001679A1 CL2022001679A CL2022001679A CL2022001679A1 CL 2022001679 A1 CL2022001679 A1 CL 2022001679A1 CL 2022001679 A CL2022001679 A CL 2022001679A CL 2022001679 A CL2022001679 A CL 2022001679A CL 2022001679 A1 CL2022001679 A1 CL 2022001679A1
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CL
Chile
Prior art keywords
dodecadienyl
coenzyme
derivatives
production
yeast cells
Prior art date
Application number
CL2022001679A
Other languages
English (en)
Inventor
Borodina Irina
Holkenbrink Carina
Löfstedt Christer
Ding Baojian
Wenning Leonie
Original Assignee
Biophero Aps
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biophero Aps filed Critical Biophero Aps
Publication of CL2022001679A1 publication Critical patent/CL2022001679A1/es

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/16—Yeasts; Culture media therefor
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N31/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
    • A01N31/02—Acyclic compounds
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/30—Microbial fungi; Substances produced thereby or obtained therefrom
    • A01N63/32—Yeast
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Botany (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

La presente invención se refiere a células de levaduras diseñadas por ingeniería genética para la producción de E8,E10-dodecadienil coenzima A, codlemona (E8,E10-dodecadien-1-ol), y opcionalmente sus derivados acetato de E8,E10-dodecadienilo y/o E8,E10-dodecadienal. También se proporcionan métodos para la producción de E8,E10-dodecadienil coenzima A, codlemona (E8,E10-dodecadien-1-ol), y opcionalmente sus derivados acetato de E8,E10-dodecadienilo y/o E8,E10-dodecadienal. También se proporcionan constructos de ácido nucleico útiles para obtener tales células de levadura.
CL2022001679A 2019-12-20 2022-06-17 Células de levadura y métodos para la producción de e8,e10-dodecadienil coenzima a, codlemona y derivados CL2022001679A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP19218703 2019-12-20

Publications (1)

Publication Number Publication Date
CL2022001679A1 true CL2022001679A1 (es) 2023-02-24

Family

ID=69147428

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2022001679A CL2022001679A1 (es) 2019-12-20 2022-06-17 Células de levadura y métodos para la producción de e8,e10-dodecadienil coenzima a, codlemona y derivados

Country Status (11)

Country Link
EP (1) EP4077636A1 (es)
JP (1) JP2023507647A (es)
KR (1) KR20220118442A (es)
CN (1) CN115103900A (es)
AU (1) AU2020407273A1 (es)
BR (1) BR112022012109A2 (es)
CA (1) CA3161539A1 (es)
CL (1) CL2022001679A1 (es)
IL (1) IL293960A (es)
MX (1) MX2022007696A (es)
WO (1) WO2021123128A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111690587B (zh) * 2019-03-13 2022-10-25 上海凯赛生物技术股份有限公司 一种离心筛选具有高含油率油脂酵母菌株的方法及其应用
CN112410355B (zh) * 2020-11-23 2022-03-25 昆明理工大学 一种酰基辅酶a氧化酶2基因rkacox2及其应用
CA3225388A1 (en) 2021-08-06 2023-02-09 Anders Gabrielsson Method for producing fatty aldehydes and derivatives thereof
WO2023175065A1 (en) 2022-03-16 2023-09-21 Biophero Aps Stabilization of aldehydes and/or an alcohols
WO2024008622A1 (en) 2022-07-04 2024-01-11 FMC Agricultural Solutions A/S Biopesticide composition

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112017027527A2 (pt) * 2015-06-26 2018-09-11 Univ Danmarks Tekniske ?método para a produção de feromônios de mariposas em levedura
PL3555269T3 (pl) * 2016-12-16 2022-12-19 Danmarks Tekniske Universitet Wytwarzanie desaturowanych alkoholi tłuszczowych i desaturowanych octanów acyli tłuszczowych w drożdżach
CN110300799B (zh) 2016-12-16 2024-01-19 丹麦科技大学 在酵母中产生脂肪醇及其衍生物的方法
CN110914442A (zh) * 2017-05-17 2020-03-24 普罗维维股份有限公司 用于产生昆虫信息素及相关化合物的微生物
US20230332096A1 (en) 2019-02-19 2023-10-19 Biophero Aps Methods and cell factories for producing insect pheromones

Also Published As

Publication number Publication date
EP4077636A1 (en) 2022-10-26
MX2022007696A (es) 2022-09-23
AU2020407273A1 (en) 2022-07-14
BR112022012109A2 (pt) 2022-12-13
IL293960A (en) 2022-08-01
WO2021123128A1 (en) 2021-06-24
CN115103900A (zh) 2022-09-23
KR20220118442A (ko) 2022-08-25
CA3161539A1 (en) 2021-06-24
JP2023507647A (ja) 2023-02-24

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