CL2020002624A1 - Formulaciones de inmunoconjugado anti-cd79b estables. - Google Patents

Formulaciones de inmunoconjugado anti-cd79b estables.

Info

Publication number
CL2020002624A1
CL2020002624A1 CL2020002624A CL2020002624A CL2020002624A1 CL 2020002624 A1 CL2020002624 A1 CL 2020002624A1 CL 2020002624 A CL2020002624 A CL 2020002624A CL 2020002624 A CL2020002624 A CL 2020002624A CL 2020002624 A1 CL2020002624 A1 CL 2020002624A1
Authority
CL
Chile
Prior art keywords
cd79b immunoconjugate
stable anti
immunoconjugate formulations
formulations
cd79b
Prior art date
Application number
CL2020002624A
Other languages
English (en)
Inventor
Ankit R Patel
Jun Liu
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of CL2020002624A1 publication Critical patent/CL2020002624A1/es

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
    • A61K47/6811—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
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    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
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    • A61K38/08—Peptides having 5 to 11 amino acids
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    • A61K47/6889—Conjugates wherein the antibody being the modifying agent and wherein the linker, binder or spacer confers particular properties to the conjugates, e.g. peptidic enzyme-labile linkers or acid-labile linkers, providing for an acid-labile immuno conjugate wherein the drug may be released from its antibody conjugated part in an acidic, e.g. tumoural or environment
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Abstract

La divulgación proporciona composiciones farmacéuticas estables que comprenden un inmunoconjugado anti-CD79b y un tensioactivo. La divulgación también proporciona métodos para usar tales composiciones para el tratamiento del cáncer.
CL2020002624A 2018-04-13 2020-10-09 Formulaciones de inmunoconjugado anti-cd79b estables. CL2020002624A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201862657185P 2018-04-13 2018-04-13

Publications (1)

Publication Number Publication Date
CL2020002624A1 true CL2020002624A1 (es) 2021-01-29

Family

ID=68161211

Family Applications (2)

Application Number Title Priority Date Filing Date
CL2020002624A CL2020002624A1 (es) 2018-04-13 2020-10-09 Formulaciones de inmunoconjugado anti-cd79b estables.
CL2021001956A CL2021001956A1 (es) 2018-04-13 2021-07-23 Formulaciones de inmunoconjugado anti-cd79b estables. (divisional solicitud 202002624)

Family Applications After (1)

Application Number Title Priority Date Filing Date
CL2021001956A CL2021001956A1 (es) 2018-04-13 2021-07-23 Formulaciones de inmunoconjugado anti-cd79b estables. (divisional solicitud 202002624)

Country Status (17)

Country Link
US (1) US11648317B2 (es)
EP (1) EP3773721A4 (es)
JP (3) JP6761506B2 (es)
KR (1) KR20210003147A (es)
CN (2) CN113384711A (es)
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