MX2020010729A - Formulaciones de inmunoconjugado anti-cd79b estables. - Google Patents

Formulaciones de inmunoconjugado anti-cd79b estables.

Info

Publication number
MX2020010729A
MX2020010729A MX2020010729A MX2020010729A MX2020010729A MX 2020010729 A MX2020010729 A MX 2020010729A MX 2020010729 A MX2020010729 A MX 2020010729A MX 2020010729 A MX2020010729 A MX 2020010729A MX 2020010729 A MX2020010729 A MX 2020010729A
Authority
MX
Mexico
Prior art keywords
cd79b immunoconjugate
stable anti
immunoconjugate formulations
formulations
cd79b
Prior art date
Application number
MX2020010729A
Other languages
English (en)
Inventor
Jun Liu
Ankit R Patel
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of MX2020010729A publication Critical patent/MX2020010729A/es

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591—Stabilisation, fragmentation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
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    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
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    • A61K38/08—Peptides having 5 to 11 amino acids
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    • A61K47/6889—Conjugates wherein the antibody being the modifying agent and wherein the linker, binder or spacer confers particular properties to the conjugates, e.g. peptidic enzyme-labile linkers or acid-labile linkers, providing for an acid-labile immuno conjugate wherein the drug may be released from its antibody conjugated part in an acidic, e.g. tumoural or environment
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Abstract

La divulgación proporciona composiciones farmacéuticas estables que comprenden un inmunoconjugado anti-CD79b y un tensioactivo. La divulgación también proporciona métodos para usar tales composiciones para el tratamiento del cáncer.
MX2020010729A 2018-04-13 2019-04-12 Formulaciones de inmunoconjugado anti-cd79b estables. MX2020010729A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862657185P 2018-04-13 2018-04-13
PCT/US2019/027329 WO2019200322A1 (en) 2018-04-13 2019-04-12 Stable anti-cd79b immunoconjugate formulations

Publications (1)

Publication Number Publication Date
MX2020010729A true MX2020010729A (es) 2021-03-09

Family

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Family Applications (2)

Application Number Title Priority Date Filing Date
MX2020010729A MX2020010729A (es) 2018-04-13 2019-04-12 Formulaciones de inmunoconjugado anti-cd79b estables.
MX2022014457A MX2022014457A (es) 2018-04-13 2020-10-09 Formulaciones de inmunoconjugado anti-cd79b estables.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2022014457A MX2022014457A (es) 2018-04-13 2020-10-09 Formulaciones de inmunoconjugado anti-cd79b estables.

Country Status (17)

Country Link
US (1) US11648317B2 (es)
EP (1) EP3773721A4 (es)
JP (3) JP6761506B2 (es)
KR (1) KR20210003147A (es)
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