CL2020002510A1 - Radiofármaco dirigido a antígeno de membrana específico de próstata (psma) para diagnosticar y tratar el cáncer de próstata - Google Patents

Radiofármaco dirigido a antígeno de membrana específico de próstata (psma) para diagnosticar y tratar el cáncer de próstata

Info

Publication number
CL2020002510A1
CL2020002510A1 CL2020002510A CL2020002510A CL2020002510A1 CL 2020002510 A1 CL2020002510 A1 CL 2020002510A1 CL 2020002510 A CL2020002510 A CL 2020002510A CL 2020002510 A CL2020002510 A CL 2020002510A CL 2020002510 A1 CL2020002510 A1 CL 2020002510A1
Authority
CL
Chile
Prior art keywords
psma
diagnose
specific membrane
membrane antigen
prostate cancer
Prior art date
Application number
CL2020002510A
Other languages
English (en)
Inventor
Dae Yoon Chi
Byoung Se Lee
So Young Chu
Hyeon Jin Jeong
Min Hwan Kim
Original Assignee
Futurechem Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Futurechem Co Ltd filed Critical Futurechem Co Ltd
Publication of CL2020002510A1 publication Critical patent/CL2020002510A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D257/00Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0474Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0487Metallocenes, i.e. complexes based on a radioactive metal complexed by two cyclopentadienyl anions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0402Organic compounds carboxylic acid carriers, fatty acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0474Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0497Organic compounds conjugates with a carrier being an organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/003Compounds containing elements of Groups 3 or 13 of the Periodic Table without C-Metal linkages

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Optics & Photonics (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

RADIOFÁRMACO DIRIGIDO A ANTÍGENO DE MEMBRANA ESPECÍFICO DE PRÓSTATA (PSMA) PARA DIAGNOSTICAR Y TRATAR EL CÁNCER DE PRÓSTATA
CL2020002510A 2018-03-30 2020-09-28 Radiofármaco dirigido a antígeno de membrana específico de próstata (psma) para diagnosticar y tratar el cáncer de próstata CL2020002510A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR20180037226 2018-03-30

Publications (1)

Publication Number Publication Date
CL2020002510A1 true CL2020002510A1 (es) 2021-02-19

Family

ID=68058285

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2020002510A CL2020002510A1 (es) 2018-03-30 2020-09-28 Radiofármaco dirigido a antígeno de membrana específico de próstata (psma) para diagnosticar y tratar el cáncer de próstata

Country Status (26)

Country Link
US (1) US11931431B2 (es)
EP (1) EP3778592B1 (es)
JP (1) JP7094591B2 (es)
KR (1) KR102156385B1 (es)
CN (1) CN112004812B (es)
AU (1) AU2019243408B2 (es)
BR (1) BR112020019566A2 (es)
CA (1) CA3094620C (es)
CL (1) CL2020002510A1 (es)
DK (1) DK3778592T3 (es)
EA (1) EA202092333A1 (es)
ES (1) ES2947748T3 (es)
FI (1) FI3778592T3 (es)
HR (1) HRP20230604T1 (es)
HU (1) HUE062904T2 (es)
LT (1) LT3778592T (es)
MX (1) MX2020010266A (es)
MY (1) MY197419A (es)
PH (1) PH12020551471A1 (es)
PL (1) PL3778592T3 (es)
PT (1) PT3778592T (es)
RS (1) RS64296B1 (es)
SG (1) SG11202009649RA (es)
SI (1) SI3778592T1 (es)
WO (1) WO2019190266A1 (es)
ZA (1) ZA202006008B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102269315B1 (ko) * 2019-10-24 2021-06-24 서울대학교산학협력단 전립선 암의 영상 또는 치료를 위한 동위원소 표지 화합물
CA3155519A1 (en) * 2019-10-29 2021-05-06 Steve Shih-Lin Huang Psma-targeting imaging agents
KR20220006286A (ko) 2020-07-08 2022-01-17 한국원자력의학원 전립선암 진단 및 치료를 위한 전립선특이 막 항원 표적 화합물 및 이를 포함하는 전립선암 진단 및 치료용 조성물
KR20230050552A (ko) * 2021-10-07 2023-04-17 (주)퓨쳐켐 가돌리늄 화합물 및 이를 포함하는 전립선암의 진단 및 치료용 약학적 조성물

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2844151C (en) 2011-08-05 2022-11-29 John W. Babich Radiolabeled prostate specific membrane antigen inhibitors
CN108042811A (zh) * 2012-11-15 2018-05-18 恩多塞特公司 用于治疗由psma表达细胞引起的疾病的共轭物
HUE035739T2 (en) 2013-01-14 2018-05-28 Molecular Insight Pharm Inc Triazine-based radiopharmaceuticals and radiological imaging agents
LT4095130T (lt) 2013-10-18 2024-04-25 Novartis Ag Žymėti prostatos specifinio membranos antigeno (psma) inhibitoriai, jų naudojimas kaip vizualizavimo medžiagų ir farmacinių medžiagų prostatos vėžiui gydyti
US10683272B2 (en) * 2014-05-06 2020-06-16 The Johns Hopkins University Metal/radiometal-labeled PSMA inhibitors for PSMA-targeted imaging and radiotherapy
KR20230147751A (ko) * 2016-03-22 2023-10-23 더 존스 홉킨스 유니버시티 전립선 암의 내부방사선요법을 위한 전립선-특이적 막 항원 표적화된 고-친화성 제제
US20210276971A1 (en) * 2018-06-20 2021-09-09 The Research Foundation For The State University Of New York Triazamacrocycle-derived chelator compositions for coordination of imaging and therapy metal ions and methods of using same

Also Published As

Publication number Publication date
RS64296B1 (sr) 2023-07-31
LT3778592T (lt) 2023-06-26
KR102156385B1 (ko) 2020-09-15
JP7094591B2 (ja) 2022-07-04
AU2019243408B2 (en) 2021-10-14
HUE062904T2 (hu) 2023-12-28
EP3778592A1 (en) 2021-02-17
WO2019190266A1 (ko) 2019-10-03
PL3778592T3 (pl) 2023-11-27
CA3094620C (en) 2022-11-22
EP3778592B1 (en) 2023-04-26
US20210106701A1 (en) 2021-04-15
PT3778592T (pt) 2023-06-19
EA202092333A1 (ru) 2021-01-21
CN112004812B (zh) 2023-05-26
MY197419A (en) 2023-06-16
ES2947748T3 (es) 2023-08-17
SI3778592T1 (sl) 2023-08-31
HRP20230604T1 (hr) 2023-09-29
DK3778592T3 (da) 2023-06-19
KR20190114908A (ko) 2019-10-10
BR112020019566A2 (pt) 2021-01-05
AU2019243408A1 (en) 2020-10-29
JP2021519822A (ja) 2021-08-12
CA3094620A1 (en) 2019-10-03
MX2020010266A (es) 2020-11-06
US11931431B2 (en) 2024-03-19
EP3778592A4 (en) 2021-02-17
FI3778592T3 (fi) 2023-06-19
PH12020551471A1 (en) 2021-09-01
ZA202006008B (en) 2021-10-27
CN112004812A (zh) 2020-11-27
SG11202009649RA (en) 2020-10-29

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