LT3778592T - Psma veikiantys radioaktyvieji preparatai, skirti prostatos vėžio diagnozei ir gydymui - Google Patents

Psma veikiantys radioaktyvieji preparatai, skirti prostatos vėžio diagnozei ir gydymui

Info

Publication number
LT3778592T
LT3778592T LTEPPCT/KR2019/003716T LTKR2019003716T LT3778592T LT 3778592 T LT3778592 T LT 3778592T LT KR2019003716 T LTKR2019003716 T LT KR2019003716T LT 3778592 T LT3778592 T LT 3778592T
Authority
LT
Lithuania
Prior art keywords
psma
diagnosing
prostate cancer
treating prostate
targeted radiopharmaceutical
Prior art date
Application number
LTEPPCT/KR2019/003716T
Other languages
English (en)
Inventor
Dae Yoon Chi
Byoung Se Lee
So Young Chu
Hyeon Jin Jeong
Min Hwan Kim
Kyo Chul Lee
Yong Jin Lee
Original Assignee
Futurechem Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Futurechem Co., Ltd. filed Critical Futurechem Co., Ltd.
Publication of LT3778592T publication Critical patent/LT3778592T/lt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0474Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0487Metallocenes, i.e. complexes based on a radioactive metal complexed by two cyclopentadienyl anions
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D257/00Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0402Organic compounds carboxylic acid carriers, fatty acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0474Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0497Organic compounds conjugates with a carrier being an organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/003Compounds containing elements of Groups 3 or 13 of the Periodic Table without C-Metal linkages

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Optics & Photonics (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
LTEPPCT/KR2019/003716T 2018-03-30 2019-03-29 Psma veikiantys radioaktyvieji preparatai, skirti prostatos vėžio diagnozei ir gydymui LT3778592T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20180037226 2018-03-30
PCT/KR2019/003716 WO2019190266A1 (ko) 2018-03-30 2019-03-29 전립선암 진단 및 치료를 위한 psma-표적 방사성의약품

Publications (1)

Publication Number Publication Date
LT3778592T true LT3778592T (lt) 2023-06-26

Family

ID=68058285

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEPPCT/KR2019/003716T LT3778592T (lt) 2018-03-30 2019-03-29 Psma veikiantys radioaktyvieji preparatai, skirti prostatos vėžio diagnozei ir gydymui

Country Status (26)

Country Link
US (1) US11931431B2 (lt)
EP (1) EP3778592B1 (lt)
JP (1) JP7094591B2 (lt)
KR (1) KR102156385B1 (lt)
CN (1) CN112004812B (lt)
AU (1) AU2019243408B2 (lt)
BR (1) BR112020019566A2 (lt)
CA (1) CA3094620C (lt)
CL (1) CL2020002510A1 (lt)
DK (1) DK3778592T3 (lt)
EA (1) EA202092333A1 (lt)
ES (1) ES2947748T3 (lt)
FI (1) FI3778592T3 (lt)
HR (1) HRP20230604T1 (lt)
HU (1) HUE062904T2 (lt)
LT (1) LT3778592T (lt)
MX (1) MX2020010266A (lt)
MY (1) MY197419A (lt)
PH (1) PH12020551471A1 (lt)
PL (1) PL3778592T3 (lt)
PT (1) PT3778592T (lt)
RS (1) RS64296B1 (lt)
SG (1) SG11202009649RA (lt)
SI (1) SI3778592T1 (lt)
WO (1) WO2019190266A1 (lt)
ZA (1) ZA202006008B (lt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102269315B1 (ko) * 2019-10-24 2021-06-24 서울대학교산학협력단 전립선 암의 영상 또는 치료를 위한 동위원소 표지 화합물
WO2021086917A1 (en) * 2019-10-29 2021-05-06 The Cleveland Clinic Foundation Psma-targeting imaging agents
KR20220006286A (ko) 2020-07-08 2022-01-17 한국원자력의학원 전립선암 진단 및 치료를 위한 전립선특이 막 항원 표적 화합물 및 이를 포함하는 전립선암 진단 및 치료용 조성물
KR20230050552A (ko) * 2021-10-07 2023-04-17 (주)퓨쳐켐 가돌리늄 화합물 및 이를 포함하는 전립선암의 진단 및 치료용 약학적 조성물

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8926944B2 (en) * 2011-08-05 2015-01-06 Molecular Insight Pharmaceuticals Radiolabeled prostate specific membrane antigen inhibitors
JP6892218B2 (ja) * 2012-11-15 2021-06-23 エンドサイト・インコーポレイテッドEndocyte, Inc. 薬物送達結合体およびpsma発現細胞によって引き起こされる疾患の治療方法
SG11201505477TA (en) 2013-01-14 2015-08-28 Molecular Insight Pharm Inc Triazine based radiopharmaceuticals and radioimaging agents
GEP20237496B (en) 2013-10-18 2023-04-10 Deutsches Krebsforsch Labeled inhibitors of prostate specific membrane antigen (psma), their use as imaging agents and pharmaceutical agents for the treatment of prostate cancer
JP6749249B2 (ja) * 2014-05-06 2020-09-02 ザ ジョンズ ホプキンズ ユニヴァーシティー Psmaを標的としたイメージング及び放射線治療のための金属/放射性金属標識psma阻害剤
EP3925952B1 (en) * 2016-03-22 2023-11-29 The Johns Hopkins University Prostate-specific membrane antigen targeted high-affinity agents for endoradiotherapy of prostate cancer
US20210276971A1 (en) * 2018-06-20 2021-09-09 The Research Foundation For The State University Of New York Triazamacrocycle-derived chelator compositions for coordination of imaging and therapy metal ions and methods of using same

Also Published As

Publication number Publication date
HRP20230604T1 (hr) 2023-09-29
ES2947748T3 (es) 2023-08-17
MY197419A (en) 2023-06-16
US11931431B2 (en) 2024-03-19
RS64296B1 (sr) 2023-07-31
CA3094620A1 (en) 2019-10-03
CN112004812B (zh) 2023-05-26
JP7094591B2 (ja) 2022-07-04
KR20190114908A (ko) 2019-10-10
HUE062904T2 (hu) 2023-12-28
CN112004812A (zh) 2020-11-27
EP3778592B1 (en) 2023-04-26
ZA202006008B (en) 2021-10-27
EA202092333A1 (ru) 2021-01-21
CA3094620C (en) 2022-11-22
DK3778592T3 (da) 2023-06-19
SI3778592T1 (sl) 2023-08-31
US20210106701A1 (en) 2021-04-15
JP2021519822A (ja) 2021-08-12
PT3778592T (pt) 2023-06-19
CL2020002510A1 (es) 2021-02-19
WO2019190266A1 (ko) 2019-10-03
SG11202009649RA (en) 2020-10-29
AU2019243408B2 (en) 2021-10-14
AU2019243408A1 (en) 2020-10-29
MX2020010266A (es) 2020-11-06
BR112020019566A2 (pt) 2021-01-05
PL3778592T3 (pl) 2023-11-27
PH12020551471A1 (en) 2021-09-01
KR102156385B1 (ko) 2020-09-15
EP3778592A1 (en) 2021-02-17
EP3778592A4 (en) 2021-02-17
FI3778592T3 (fi) 2023-06-19

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