CL2018000415A1 - Receptor quimerica de citocinas. - Google Patents

Receptor quimerica de citocinas.

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Publication number
CL2018000415A1
CL2018000415A1 CL2018000415A CL2018000415A CL2018000415A1 CL 2018000415 A1 CL2018000415 A1 CL 2018000415A1 CL 2018000415 A CL2018000415 A CL 2018000415A CL 2018000415 A CL2018000415 A CL 2018000415A CL 2018000415 A1 CL2018000415 A1 CL 2018000415A1
Authority
CL
Chile
Prior art keywords
cytokine
chimeric receptor
receptor
exodominum
endodominium
Prior art date
Application number
CL2018000415A
Other languages
English (en)
Inventor
Martin Pulé
Shaun Cordoba
Simon Thomas
Shimobi Onuoha
Matteo Righi
James Sillibourne
Original Assignee
Autolus Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Autolus Ltd filed Critical Autolus Ltd
Publication of CL2018000415A1 publication Critical patent/CL2018000415A1/es

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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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    • A61K39/001102—Receptors, cell surface antigens or cell surface determinants
    • A61K39/001116—Receptors for cytokines
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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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    • C12N15/09—Recombinant DNA-technology
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    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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Abstract

<p>LA PRESENTE INVENCIÓN PROPORCIONA UN RECEPTOR QUIMÉRICO DE CITOCINAS (CCR) QUE COMPRENDE: (I) UN EXODOMINIO QUE SE UNE A UN LIGANDO SELECCIONADO DE ENTRE UN FACTOR SECRETADO POR TUMOR, UNA QUIMIOCINA Y UN ANTÍGENO DE SUPERFICIE CELULAR; Y (II) UN ENDODOMINIO DE RECEPTOR DE CITOCINAS.</p>
CL2018000415A 2015-08-20 2018-02-15 Receptor quimerica de citocinas. CL2018000415A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1514875.2A GB201514875D0 (en) 2015-08-20 2015-08-20 Receptor

Publications (1)

Publication Number Publication Date
CL2018000415A1 true CL2018000415A1 (es) 2018-07-20

Family

ID=54292003

Family Applications (2)

Application Number Title Priority Date Filing Date
CL2018000415A CL2018000415A1 (es) 2015-08-20 2018-02-15 Receptor quimerica de citocinas.
CL2019001107A CL2019001107A1 (es) 2015-08-20 2019-04-23 Receptor quimérico de citocinas. (divisional solicitud 201800415).

Family Applications After (1)

Application Number Title Priority Date Filing Date
CL2019001107A CL2019001107A1 (es) 2015-08-20 2019-04-23 Receptor quimérico de citocinas. (divisional solicitud 201800415).

Country Status (15)

Country Link
US (5) US10800854B2 (es)
EP (3) EP4338756A3 (es)
JP (4) JP2018523485A (es)
CN (2) CN110724200B (es)
AU (1) AU2016308618B2 (es)
BR (1) BR112018003308A2 (es)
CA (2) CA2995785A1 (es)
CL (2) CL2018000415A1 (es)
GB (1) GB201514875D0 (es)
HK (1) HK1252161A1 (es)
IL (2) IL270207B1 (es)
MX (2) MX2018002042A (es)
RU (1) RU2018109350A (es)
SG (1) SG10201909759UA (es)
WO (1) WO2017029512A1 (es)

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