CL2017000987A1 - Partículas tipo virus modificadas de cmv - Google Patents
Partículas tipo virus modificadas de cmvInfo
- Publication number
- CL2017000987A1 CL2017000987A1 CL2017000987A CL2017000987A CL2017000987A1 CL 2017000987 A1 CL2017000987 A1 CL 2017000987A1 CL 2017000987 A CL2017000987 A CL 2017000987A CL 2017000987 A CL2017000987 A CL 2017000987A CL 2017000987 A1 CL2017000987 A1 CL 2017000987A1
- Authority
- CL
- Chile
- Prior art keywords
- vlps
- cmv
- virus type
- virus
- type particles
- Prior art date
Links
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- A—HUMAN NECESSITIES
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- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/646—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
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- C07—ORGANIC CHEMISTRY
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- C07K2319/00—Fusion polypeptide
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
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- General Engineering & Computer Science (AREA)
Abstract
<p>LA PRESENTE INVENCIÓN SE REFIERE A PARTICULAR TIPO VIRUS (VLPs POR SUS SIGLAS EN INGLÉS) DEL VIRUS DE PLANTAS VIRUS DEL MOSAICO DEL PEPINO (CMV POR SUS SIGLAS EN INGLÉS), Y EN PARTICULAR A VLPs DE CMV QUE COMPRENDEN EPÍTOPOS DE CÉLULAS Th, EN PARTICULAR EPÍTOPOS DE CÉLULAS Th UNIVERSALES. ADEMÁS, ESTAS VLPs MODIFICADAS SIRVEN COMO, PREFERENTEMENTE, PLATAFORMA DE VACUNA, PARE LA GENERACIÓN DE RESPUESTAS INMUNES, EN RESPUESTAS DE ANTICUERPOS PARTICULARES, CONTRA LOS ANTÍGENOS VINCULADOS CON DICHAS VLPs MODIFICADAS. LA PRESENCIA DE LOS EPÍTOPOS DE CÉLULAS Th, EN PARTICULAR EPÍTOPOS DE CÉLULAS Th UNIVERSALES, CONDUJO A UN MAYOR AUMENTO EN LA RESPUESTA INMUNE GENERADA.</p>
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US10946078B2 (en) * | 2016-04-27 | 2021-03-16 | Benchmark Animal Health Ltd. | Treatment of canine atopic dermatitis |
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CA3054389A1 (en) * | 2017-03-07 | 2018-09-13 | Universitat Zurich | Treatment of pruritus in horses |
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BR112020017715A2 (pt) * | 2018-03-16 | 2020-12-29 | Zoetis Services Llc | Vacinas de peptídeo contra interleucina-31 |
TW202003031A (zh) | 2018-04-10 | 2020-01-16 | 瑞士商Ac免疫有限公司 | 抗Aβ治療性疫苗 |
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CA3121843A1 (en) * | 2018-12-20 | 2020-06-25 | Saiba AG | Virus-like particles of cmv modified by fusion |
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US20230038487A1 (en) * | 2019-11-25 | 2023-02-09 | The Regents Of The University Of California | Modified viral therapeutics and uses thereof |
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