CL2017000987A1 - Partículas tipo virus modificadas de cmv - Google Patents
Partículas tipo virus modificadas de cmvInfo
- Publication number
- CL2017000987A1 CL2017000987A1 CL2017000987A CL2017000987A CL2017000987A1 CL 2017000987 A1 CL2017000987 A1 CL 2017000987A1 CL 2017000987 A CL2017000987 A CL 2017000987A CL 2017000987 A CL2017000987 A CL 2017000987A CL 2017000987 A1 CL2017000987 A1 CL 2017000987A1
- Authority
- CL
- Chile
- Prior art keywords
- vlps
- cmv
- virus type
- virus
- type particles
- Prior art date
Links
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- A—HUMAN NECESSITIES
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- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/646—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
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- C07—ORGANIC CHEMISTRY
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- C07K2319/00—Fusion polypeptide
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
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- General Engineering & Computer Science (AREA)
Abstract
<p>LA PRESENTE INVENCIÓN SE REFIERE A PARTICULAR TIPO VIRUS (VLPs POR SUS SIGLAS EN INGLÉS) DEL VIRUS DE PLANTAS VIRUS DEL MOSAICO DEL PEPINO (CMV POR SUS SIGLAS EN INGLÉS), Y EN PARTICULAR A VLPs DE CMV QUE COMPRENDEN EPÍTOPOS DE CÉLULAS Th, EN PARTICULAR EPÍTOPOS DE CÉLULAS Th UNIVERSALES. ADEMÁS, ESTAS VLPs MODIFICADAS SIRVEN COMO, PREFERENTEMENTE, PLATAFORMA DE VACUNA, PARE LA GENERACIÓN DE RESPUESTAS INMUNES, EN RESPUESTAS DE ANTICUERPOS PARTICULARES, CONTRA LOS ANTÍGENOS VINCULADOS CON DICHAS VLPs MODIFICADAS. LA PRESENCIA DE LOS EPÍTOPOS DE CÉLULAS Th, EN PARTICULAR EPÍTOPOS DE CÉLULAS Th UNIVERSALES, CONDUJO A UN MAYOR AUMENTO EN LA RESPUESTA INMUNE GENERADA.</p>
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WO2017179025A1 (en) | 2016-04-15 | 2017-10-19 | Alk-Abelló A/S | Epitope polypeptides of ragweed pollen allergens |
CN109562156B (zh) * | 2016-04-27 | 2023-03-10 | 标杆动物健康有限公司 | 犬特应性皮炎的治疗 |
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CA3054389A1 (en) * | 2017-03-07 | 2018-09-13 | Universitat Zurich | Treatment of pruritus in horses |
WO2019118512A2 (en) * | 2017-12-11 | 2019-06-20 | Ubi Ip Holdings | Peptide immunogens of il-31 and formulations thereof for the treatment and/or prevention of atopic dermatitis |
BR112020017715A2 (pt) | 2018-03-16 | 2020-12-29 | Zoetis Services Llc | Vacinas de peptídeo contra interleucina-31 |
EP3801604A1 (en) | 2018-05-28 | 2021-04-14 | Evax AG | Treatment of urticaria |
MX2021007285A (es) | 2018-12-20 | 2021-09-23 | Saiba AG | Particulas similares a virus del cmv modificadas por fusion. |
BR112021012906A2 (pt) * | 2018-12-31 | 2021-12-28 | United Neuroscience Ltd | Imunógenos de peptídeo que têm como alvo peptídeo relacionado ao gene da calcitonina (cgrp) e formulações dos mesmos para prevenção e tratamento de enxaqueca |
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US20230038487A1 (en) * | 2019-11-25 | 2023-02-09 | The Regents Of The University Of California | Modified viral therapeutics and uses thereof |
WO2021260131A1 (en) | 2020-06-25 | 2021-12-30 | Saiba AG | Virus-like particles of cmv modified by fusion |
JP2023550628A (ja) * | 2020-11-23 | 2023-12-04 | スカウト バイオ, インコーポレイテッド | 抗原結合分子およびその使用 |
CN112724204B (zh) * | 2020-12-15 | 2023-12-19 | 深圳赫兹生命科学技术有限公司 | 一种用于生产vlp重组疫苗的cmv病毒样颗粒及其制备方法 |
WO2023139103A1 (en) | 2022-01-19 | 2023-07-27 | Universität Bern | Compositions of virus-like particles and microcrystalline tyrosine |
CN114437211B (zh) * | 2022-01-26 | 2024-03-12 | 南京麦西崴克生物科技有限公司 | 基于猫过敏原Fel d1的卵黄抗体的制备方法 |
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