CL2016001375A1 - Composición, que comprende agente bioactivo (inmunógeno) dispersado en gotitas de aceite, polímero de recubrimiento entérico, un polímero mucoadhesivo, su método de preparación y uso para la administración oral de un agente bioactivo. - Google Patents
Composición, que comprende agente bioactivo (inmunógeno) dispersado en gotitas de aceite, polímero de recubrimiento entérico, un polímero mucoadhesivo, su método de preparación y uso para la administración oral de un agente bioactivo.Info
- Publication number
- CL2016001375A1 CL2016001375A1 CL2016001375A CL2016001375A CL2016001375A1 CL 2016001375 A1 CL2016001375 A1 CL 2016001375A1 CL 2016001375 A CL2016001375 A CL 2016001375A CL 2016001375 A CL2016001375 A CL 2016001375A CL 2016001375 A1 CL2016001375 A1 CL 2016001375A1
- Authority
- CL
- Chile
- Prior art keywords
- bioactive agent
- polymer
- dispersed
- enteric coating
- composition
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/26—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests in coated particulate form
- A01N25/28—Microcapsules or nanocapsules
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
- A01N43/04—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
- A01N43/14—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom six-membered rings
- A01N43/16—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom six-membered rings with oxygen as the ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/025—Enterobacteriales, e.g. Enterobacter
- A61K39/0275—Salmonella
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/107—Vibrio
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/35—Allergens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/542—Mucosal route oral/gastrointestinal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- A61K2039/575—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
Abstract
Una composición para la administración oral de un agente bioactivo a especies acuáticas o terrestres que incluye partículas, cada una de las cuales incluye un agente bioactivo dispersado en gotitas de aceite, las gotitas de aceite estando dispersadas en una matriz que incluye un polímero de recubrimiento entérico, en donde cada una de las partículas además incluye un polímero mucoadhesivo. Un método de preparación de dicha composición que comprende en secuencia: (a) la formación de una mezcla acuosa que comprende un agente bioactivo disperso o disuelto; (b) la homogenización de la mezcla acuosa de la etapa (a) en aceite para producir una emulsión de la mezcla acuosa en el aceite; (c) la formación de una suspensión del producto de la etapa (b) en una solución acuosa que comprende un polímero de recubrimiento entérico; y o bien (d1) la pulverización, goteo o inyección de la solución de la etapa (c) en una solución acuosa que contiene un agente de reticulación para el polímero de recubrimiento entérico para formar las partículas, en donde la mezcla acuosa de la etapa (a) además comprende un polímero mucoadhesivo, o (d2) la formación de las partículas a partir de la suspensión de la etapa (c) en donde la etapa (b) además incluye la formación de gotitas de la emulsión en polímero mucoadhesivo acuoso y la reticulación del polímero mucoadhesivo para formar partículas intermedias.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361912958P | 2013-12-06 | 2013-12-06 |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2016001375A1 true CL2016001375A1 (es) | 2017-05-12 |
Family
ID=53273982
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2016001375A CL2016001375A1 (es) | 2013-12-06 | 2016-06-06 | Composición, que comprende agente bioactivo (inmunógeno) dispersado en gotitas de aceite, polímero de recubrimiento entérico, un polímero mucoadhesivo, su método de preparación y uso para la administración oral de un agente bioactivo. |
Country Status (17)
Country | Link |
---|---|
US (2) | US10272036B2 (es) |
EP (1) | EP3076952A4 (es) |
JP (1) | JP6712222B2 (es) |
KR (1) | KR20160095124A (es) |
CN (2) | CN105916493A (es) |
AU (1) | AU2014357580B2 (es) |
BR (1) | BR112016012838B1 (es) |
CA (1) | CA2932681C (es) |
CL (1) | CL2016001375A1 (es) |
DK (3) | DK201670506A1 (es) |
EC (1) | ECSP16058769A (es) |
MX (1) | MX2016007356A (es) |
PH (1) | PH12016501072A1 (es) |
RU (1) | RU2688136C1 (es) |
TW (2) | TW202023621A (es) |
WO (1) | WO2015084594A1 (es) |
ZA (1) | ZA201604615B (es) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2016281617A1 (en) * | 2015-06-26 | 2018-01-18 | Advanced Bionutrition Corporation | Composition for delivery of active agents to an animal |
JP6801203B2 (ja) * | 2016-03-18 | 2020-12-16 | 日油株式会社 | pH応答溶出性被覆造粒物および食品 |
WO2017220615A1 (en) * | 2016-06-20 | 2017-12-28 | Virbac | Method and apparatus for preparing a micro-particles composition |
US20210369805A1 (en) * | 2016-08-04 | 2021-12-02 | Seattle Gummy Company | Compositions for post-exercise recovery and methods of making and using thereof |
KR102196572B1 (ko) * | 2019-10-10 | 2020-12-29 | 대한민국 | 알긴산나트륨 캡슐을 포함하는 어류용 백신 조성물 및 이의 제조방법 |
WO2023235938A1 (en) * | 2022-06-10 | 2023-12-14 | University Of South Australia | Compositions comprising lipid droplets encapsulated within polysaccharide walls and uses thereof |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH09500132A (ja) | 1993-07-12 | 1997-01-07 | ヴァイラス リサーチ インスティチュート | ヒドロゲルマイクロカプセル化ワクチン |
US5674495A (en) | 1995-02-27 | 1997-10-07 | Purdue Research Foundation | Alginate-based vaccine compositions |
JPH10130166A (ja) * | 1996-08-20 | 1998-05-19 | Freunt Ind Co Ltd | 免疫原含有微小球体、その製造方法及びそれを用いた動物の免疫方法 |
GB9710699D0 (en) | 1997-05-24 | 1997-07-16 | Danbiosyst Uk | Gastro-retentive controlled release system |
GB9818591D0 (en) | 1998-08-27 | 1998-10-21 | Danbiosyst Uk | Pharmaceutical composition |
DK1280521T3 (da) | 2000-05-12 | 2005-08-08 | Pharmacia & Upjohn Co Llc | Vaccinesammensætning, fremgangsmåde til fremstilling deraf og fremgangsmåde til vaccination af hvirveldyr |
US20030017195A1 (en) | 2001-07-20 | 2003-01-23 | Samir Mitragotri | Method for oral drug delivery |
EP1750674A4 (en) | 2004-05-27 | 2012-05-23 | Advanced Bionutrition Corp | MICROPARTICLES FOR THE ORAL LEVY |
US20080020018A1 (en) | 2004-09-27 | 2008-01-24 | Joey Moodley | Combination Products |
WO2007001448A2 (en) | 2004-11-04 | 2007-01-04 | Massachusetts Institute Of Technology | Coated controlled release polymer particles as efficient oral delivery vehicles for biopharmaceuticals |
WO2006116392A2 (en) | 2005-04-27 | 2006-11-02 | The Regents Of The University Of Michigan | Particle-containing complex porous materials |
CL2008001806A1 (es) * | 2007-06-20 | 2008-09-05 | Wyeth Corp | Composicion de vacuna en emulsion agua en aceite que comprende un antigeno y un adyuvante en la fase acuosa; y metodo de elaboracion. |
US8778384B2 (en) * | 2008-03-24 | 2014-07-15 | Advanced Bionutrition Corporation | Compositions and methods for encapsulating vaccines for the oral vaccination and boostering of fish and other animals |
US7998502B2 (en) | 2008-03-24 | 2011-08-16 | Advanced Bionutrition Corp. | Encapsulated vaccines for the oral vaccination and boostering of fish and other animals |
EP2410996B1 (en) * | 2009-03-27 | 2017-08-02 | Advanced Bionutrition Corp. | Microparticulated vaccines for the oral or nasal vaccination and boostering of animals including fish |
GB2485327A (en) * | 2009-08-12 | 2012-05-09 | Sigmoid Pharma Ltd | Immunomodulatory compositions comprising a polymer matrix and an oil phase |
US20130156858A1 (en) * | 2010-06-03 | 2013-06-20 | Rph Pharmaceuticals Ab | Formulations Preserving Bioactivity and Methods of Their Preparation |
JP2015509499A (ja) * | 2012-02-21 | 2015-03-30 | アドバンスド バイオニュートリション コーポレイション | 水生生物に生物活性剤をターゲット送達するための組成物および方法 |
JP5102401B1 (ja) | 2012-03-30 | 2012-12-19 | 森下仁丹株式会社 | 大腸特異崩壊性カプセル |
GB201212010D0 (en) | 2012-07-05 | 2012-08-22 | Sigmoid Pharma Ltd | Formulations |
GB201319791D0 (en) | 2013-11-08 | 2013-12-25 | Sigmoid Pharma Ltd | Formulations |
-
2014
- 2014-11-20 RU RU2016127263A patent/RU2688136C1/ru active
- 2014-11-20 CN CN201480073399.4A patent/CN105916493A/zh active Pending
- 2014-11-20 JP JP2016536783A patent/JP6712222B2/ja not_active Expired - Fee Related
- 2014-11-20 AU AU2014357580A patent/AU2014357580B2/en active Active
- 2014-11-20 KR KR1020167018181A patent/KR20160095124A/ko not_active Application Discontinuation
- 2014-11-20 BR BR112016012838-9A patent/BR112016012838B1/pt active IP Right Grant
- 2014-11-20 WO PCT/US2014/066510 patent/WO2015084594A1/en active Application Filing
- 2014-11-20 EP EP14868228.9A patent/EP3076952A4/en not_active Withdrawn
- 2014-11-20 MX MX2016007356A patent/MX2016007356A/es unknown
- 2014-11-20 US US15/100,764 patent/US10272036B2/en active Active
- 2014-11-20 CN CN202111080354.8A patent/CN113750075A/zh active Pending
- 2014-11-20 CA CA2932681A patent/CA2932681C/en active Active
- 2014-12-05 TW TW109100815A patent/TW202023621A/zh unknown
- 2014-12-05 TW TW103142409A patent/TW201609149A/zh unknown
-
2016
- 2016-06-06 PH PH12016501072A patent/PH12016501072A1/en unknown
- 2016-06-06 CL CL2016001375A patent/CL2016001375A1/es unknown
- 2016-07-06 DK DKPA201670506A patent/DK201670506A1/en not_active Application Discontinuation
- 2016-07-06 EC ECIEPI201658769A patent/ECSP16058769A/es unknown
- 2016-07-06 ZA ZA2016/04615A patent/ZA201604615B/en unknown
- 2016-08-16 DK DKBA201600092U patent/DK201600092U1/da not_active IP Right Cessation
-
2018
- 2018-10-25 DK DKPA201870694A patent/DK201870694A1/en not_active Application Discontinuation
-
2019
- 2019-03-06 US US16/294,359 patent/US10806698B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
EP3076952A1 (en) | 2016-10-12 |
US10806698B2 (en) | 2020-10-20 |
ECSP16058769A (es) | 2017-01-31 |
US20160296469A1 (en) | 2016-10-13 |
RU2688136C1 (ru) | 2019-05-20 |
PH12016501072B1 (en) | 2016-07-25 |
PH12016501072A1 (en) | 2016-07-25 |
CN105916493A (zh) | 2016-08-31 |
TW201609149A (zh) | 2016-03-16 |
US20190201331A1 (en) | 2019-07-04 |
BR112016012838B1 (pt) | 2023-02-28 |
KR20160095124A (ko) | 2016-08-10 |
JP2016539170A (ja) | 2016-12-15 |
CA2932681A1 (en) | 2015-06-11 |
MX2016007356A (es) | 2016-10-03 |
DK201600092U1 (da) | 2016-08-26 |
TW202023621A (zh) | 2020-07-01 |
EP3076952A4 (en) | 2017-09-20 |
US10272036B2 (en) | 2019-04-30 |
DK201870694A1 (en) | 2018-11-28 |
ZA201604615B (en) | 2019-04-24 |
JP6712222B2 (ja) | 2020-06-17 |
BR112016012838A2 (pt) | 2017-08-08 |
DK201670506A1 (en) | 2017-03-06 |
CN113750075A (zh) | 2021-12-07 |
AU2014357580A1 (en) | 2016-07-21 |
WO2015084594A1 (en) | 2015-06-11 |
CA2932681C (en) | 2022-08-30 |
AU2014357580B2 (en) | 2019-08-01 |
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