DK1280521T3 - Vaccinesammensætning, fremgangsmåde til fremstilling deraf og fremgangsmåde til vaccination af hvirveldyr - Google Patents

Vaccinesammensætning, fremgangsmåde til fremstilling deraf og fremgangsmåde til vaccination af hvirveldyr

Info

Publication number
DK1280521T3
DK1280521T3 DK01935330T DK01935330T DK1280521T3 DK 1280521 T3 DK1280521 T3 DK 1280521T3 DK 01935330 T DK01935330 T DK 01935330T DK 01935330 T DK01935330 T DK 01935330T DK 1280521 T3 DK1280521 T3 DK 1280521T3
Authority
DK
Denmark
Prior art keywords
antigen
vaccine composition
alginate
improved
microparticles
Prior art date
Application number
DK01935330T
Other languages
English (en)
Inventor
Argaw Kidane
Terry L Bowersock
Paul Guimond
Tzu-Chi R Ju
Original Assignee
Pharmacia & Upjohn Co Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Co Llc filed Critical Pharmacia & Upjohn Co Llc
Application granted granted Critical
Publication of DK1280521T3 publication Critical patent/DK1280521T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1641Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541Mucosal route
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541Mucosal route
    • A61K2039/542Mucosal route oral/gastrointestinal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55555Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55566Emulsions, e.g. Freund's adjuvant, MF59
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
DK01935330T 2000-05-12 2001-05-11 Vaccinesammensætning, fremgangsmåde til fremstilling deraf og fremgangsmåde til vaccination af hvirveldyr DK1280521T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US20386400P 2000-05-12 2000-05-12
PCT/US2001/015235 WO2001087270A2 (en) 2000-05-12 2001-05-11 Vaccine composition, method of preparing the same, and method of vaccinating vertebrates

Publications (1)

Publication Number Publication Date
DK1280521T3 true DK1280521T3 (da) 2005-08-08

Family

ID=22755628

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01935330T DK1280521T3 (da) 2000-05-12 2001-05-11 Vaccinesammensætning, fremgangsmåde til fremstilling deraf og fremgangsmåde til vaccination af hvirveldyr

Country Status (10)

Country Link
US (2) US6656470B2 (da)
EP (1) EP1280521B1 (da)
AT (1) ATE299696T1 (da)
AU (1) AU2001261433A1 (da)
DE (1) DE60112073T2 (da)
DK (1) DK1280521T3 (da)
ES (1) ES2243497T3 (da)
HK (1) HK1049800A1 (da)
PT (1) PT1280521E (da)
WO (1) WO2001087270A2 (da)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6207646B1 (en) 1994-07-15 2001-03-27 University Of Iowa Research Foundation Immunostimulatory nucleic acid molecules
US20030026782A1 (en) * 1995-02-07 2003-02-06 Arthur M. Krieg Immunomodulatory oligonucleotides
US6406705B1 (en) * 1997-03-10 2002-06-18 University Of Iowa Research Foundation Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant
US20030022854A1 (en) 1998-06-25 2003-01-30 Dow Steven W. Vaccines using nucleic acid-lipid complexes
US6693086B1 (en) * 1998-06-25 2004-02-17 National Jewish Medical And Research Center Systemic immune activation method using nucleic acid-lipid complexes
AU2001261433A1 (en) * 2000-05-12 2001-11-26 Pharmacia And Upjohn Company Vaccine composition, method of preparing the same, and method of vaccinating vertebrates
AP2003002867A0 (en) * 2001-03-05 2003-09-30 Forinnova As Immune response potentiation
FR2823119B1 (fr) * 2001-04-05 2004-02-20 Seppic Sa Adjuvant d'immunite contenant un cation metallique complexe et vaccin le contenant
US7119172B2 (en) * 2001-05-21 2006-10-10 The Brigham And Women's Hospital, Inc. P. aeruginosa mucoid exopolysaccharide specific binding peptides
WO2002094854A2 (en) * 2001-05-21 2002-11-28 The Brigham And Women's Hospital, Inc. P.aeruginosa mucoid exopolysaccharide specific binding peptides
US6678583B2 (en) * 2001-08-06 2004-01-13 Seminet, Inc. Robotic storage buffer system for substrate carrier pods
US7039499B1 (en) * 2002-08-02 2006-05-02 Seminet Inc. Robotic storage buffer system for substrate carrier pods
KR100548925B1 (ko) * 2002-10-23 2006-02-02 한미약품 주식회사 약물의 경구투여용 서방성 조성물
ES2496102T3 (es) * 2003-03-28 2014-09-18 Sigmoid Pharma Limited Forma de dosificación oral sólida que contiene microcápsulas sin fisuras
US20040235770A1 (en) * 2003-04-02 2004-11-25 Coley Pharmaceutical Group, Ltd. Immunostimulatory nucleic acid oil-in-water formulations and related methods of use
US20050013812A1 (en) * 2003-07-14 2005-01-20 Dow Steven W. Vaccines using pattern recognition receptor-ligand:lipid complexes
US7081227B2 (en) * 2004-06-07 2006-07-25 The Reagents Of The University Of California Amphiphilic mediated sample preparation for micro-flow cytometry
WO2006034395A2 (en) * 2004-09-21 2006-03-30 The Brigham And Women's Hospital, Inc. Methods and compositions relating to mannuronic acid specific binding peptides
ATE413165T1 (de) * 2004-09-27 2008-11-15 Sigmoid Pharma Ltd Mikrokapseln mit einem methylxanthin und einem kortikosteroid
WO2006059846A1 (en) * 2004-12-01 2006-06-08 Lg Life Sciences, Ltd. Formulation of sec1 mutated protein and method for formulation of the same
RU2007129840A (ru) * 2005-01-05 2009-02-20 Филадельфия Хелт Энд Эдьюкейшн Корпорейшн Д/Б/А Дрексел Юниверсити Колледж Оф Медисин (Us) Средства доставки, биологически активные вещества и вирусные вакцины
US20090238890A1 (en) * 2006-01-13 2009-09-24 Advanced Bionutrition Corporation Continuous spray-capture production system
US8911777B2 (en) * 2007-04-04 2014-12-16 Sigmoid Pharma Limited Pharmaceutical composition of tacrolimus
CA2942083C (en) * 2007-04-26 2019-01-29 Sigmoid Pharma Limited Manufacture of multiple minicapsules
WO2008132710A2 (en) * 2007-05-01 2008-11-06 Sigmoid Pharma Limited Pharmaceutical nimodipine compositions
WO2009005709A1 (en) * 2007-06-28 2009-01-08 Surmodics, Inc. Polypeptide microparticles
US9278070B2 (en) 2009-05-18 2016-03-08 Sigmoid Pharma Limited Composition comprising oil drops
EP2464341B1 (en) * 2009-08-12 2022-07-06 Sublimity Therapeutics Limited Immunomodulatory compositions comprising a polymer matrix and an oil phase
GB201020032D0 (en) 2010-11-25 2011-01-12 Sigmoid Pharma Ltd Composition
WO2013029033A2 (en) * 2011-08-25 2013-02-28 Brian Pulliam Rotavirus preparations with excess calcium ions and high viscosities that ensure vaccine viability at elevated temperatures
GB201212010D0 (en) 2012-07-05 2012-08-22 Sigmoid Pharma Ltd Formulations
GB201319791D0 (en) 2013-11-08 2013-12-25 Sigmoid Pharma Ltd Formulations
RU2688136C1 (ru) * 2013-12-06 2019-05-20 Интервет Интернэшнл Б.В. Композиция для пероральной доставки биоактивных агентов
KR20170102223A (ko) 2014-11-07 2017-09-08 시그모이드 파마 리미티드 사이클로스포린을 포함하는 조성물
WO2017097844A1 (en) 2015-12-07 2017-06-15 Schlumberger Norge As Microsphere compositions and methods for production in oil-based drilling fluids
GB202205231D0 (en) * 2022-04-09 2022-05-25 Nasaleze Patents Ltd Vaccine compositions

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1586811A (da) 1966-01-06 1970-03-06
EG10802A (en) 1971-02-19 1976-10-31 Bayer Ag A process for embeding veterinary substances and their protection against the influence of the gastric juice of the rumen
US4178361A (en) 1973-09-10 1979-12-11 Union Corporation Sustained release pharmaceutical composition
US4220152A (en) 1978-05-08 1980-09-02 Pfizer Inc. Delivery system
US4391909A (en) 1979-03-28 1983-07-05 Damon Corporation Microcapsules containing viable tissue cells
US4352883A (en) 1979-03-28 1982-10-05 Damon Corporation Encapsulation of biological material
US4798786A (en) 1982-05-06 1989-01-17 Stolle Research And Development Corporation Living cells encapsulated in crosslinked protein
CA1196862A (en) 1983-06-01 1985-11-19 Anthony M.F. Sun Microencapsulation of living tissue and cells
US4689293A (en) 1983-06-06 1987-08-25 Connaught Laboratories Limited Microencapsulation of living tissue and cells
US4806355A (en) 1983-06-06 1989-02-21 Connaught Laboratories Limited Microencapsulation of living tissue and cells
GB8326633D0 (en) 1983-08-04 1983-11-09 Unilever Plc Compositions
US4803168A (en) 1983-09-01 1989-02-07 Damon Biotech, Inc. Microencapsulation with polymers
GB8500121D0 (en) 1985-01-03 1985-02-13 Connaught Lab Microencapsulation of living cells
US4873090A (en) 1985-03-27 1989-10-10 Broncostat Pty. Limited Non-adjuvenated vaccine
US4780315A (en) 1985-11-25 1988-10-25 Eastman Kodak Company Rumen-stable pellets
US5075109A (en) 1986-10-24 1991-12-24 Southern Research Institute Method of potentiating an immune response
NL8701548A (nl) * 1987-07-01 1989-02-01 Tno Polymeer netwerk, werkwijze voor het bereiden daarvan alsmede, de toepassing daarvan voor het bekleden en/of impregneren of voor het vervaardigen van ooglenzen, alsmede gevormd voortbrengsel, geheel of ten dele bestaande uit een dergelijk polymeer netwerk.
US4792452A (en) * 1987-07-28 1988-12-20 E. R. Squibb & Sons, Inc. Controlled release formulation
US4808404A (en) 1988-01-11 1989-02-28 A. H. Robins Company, Inc. Live vaccine for coccidiosis utilizing coccidial sporozoites
JPH01313437A (ja) 1988-06-14 1989-12-18 Nippon Seibutsu Kagaku Kenkyusho 飼料内投与用の粒子状生ワクチン及びその製法並びに鶏コクシジウム症生ワクチン
FR2683147B1 (fr) 1991-10-30 1995-06-23 Maingault Philippe Systeme vehicule de principe actif permettant l'administration voie orale chez les poissons et crustaces.
US5352448A (en) 1992-07-20 1994-10-04 Purdue Research Foundatioin Oral administration of antigens
CA2167081A1 (en) 1993-07-12 1995-01-26 Alexander K. Andrianov Hydrogel microencapsulated vaccines
US5674495A (en) 1995-02-27 1997-10-07 Purdue Research Foundation Alginate-based vaccine compositions
US6214331B1 (en) * 1995-06-06 2001-04-10 C. R. Bard, Inc. Process for the preparation of aqueous dispersions of particles of water-soluble polymers and the particles obtained
US6656508B2 (en) 1997-04-17 2003-12-02 Amgen Inc. Sustained-release alginate gels
KR20010003853A (ko) * 1999-06-25 2001-01-15 박호군 경구용 백신으로 사용할 수 있는 알긴산염 마이크로스피어 및그 제조방법
AU2001261433A1 (en) * 2000-05-12 2001-11-26 Pharmacia And Upjohn Company Vaccine composition, method of preparing the same, and method of vaccinating vertebrates

Also Published As

Publication number Publication date
WO2001087270A3 (en) 2002-05-16
WO2001087270B1 (en) 2002-08-15
HK1049800A1 (en) 2003-05-30
ATE299696T1 (de) 2005-08-15
EP1280521B1 (en) 2005-07-20
DE60112073D1 (de) 2005-08-25
US6656470B2 (en) 2003-12-02
AU2001261433A1 (en) 2001-11-26
WO2001087270A2 (en) 2001-11-22
PT1280521E (pt) 2005-10-31
US20040071727A1 (en) 2004-04-15
US7160544B2 (en) 2007-01-09
US20020009457A1 (en) 2002-01-24
ES2243497T3 (es) 2005-12-01
EP1280521A2 (en) 2003-02-05
DE60112073T2 (de) 2006-04-20

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