DE60112073D1 - Impfstoffzusammensetzung und verfahren zur herstellung derselben sowie verfahren zur impfung von wirbeltieren - Google Patents
Impfstoffzusammensetzung und verfahren zur herstellung derselben sowie verfahren zur impfung von wirbeltierenInfo
- Publication number
- DE60112073D1 DE60112073D1 DE60112073T DE60112073T DE60112073D1 DE 60112073 D1 DE60112073 D1 DE 60112073D1 DE 60112073 T DE60112073 T DE 60112073T DE 60112073 T DE60112073 T DE 60112073T DE 60112073 D1 DE60112073 D1 DE 60112073D1
- Authority
- DE
- Germany
- Prior art keywords
- antigen
- vaccine composition
- alginate
- improved
- microparticles
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/542—Mucosal route oral/gastrointestinal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US20386400P | 2000-05-12 | 2000-05-12 | |
US203864P | 2000-05-12 | ||
PCT/US2001/015235 WO2001087270A2 (en) | 2000-05-12 | 2001-05-11 | Vaccine composition, method of preparing the same, and method of vaccinating vertebrates |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60112073D1 true DE60112073D1 (de) | 2005-08-25 |
DE60112073T2 DE60112073T2 (de) | 2006-04-20 |
Family
ID=22755628
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60112073T Expired - Fee Related DE60112073T2 (de) | 2000-05-12 | 2001-05-11 | Impfstoffzusammensetzung und verfahren zur herstellung derselben sowie verfahren zur impfung von wirbeltieren |
Country Status (10)
Country | Link |
---|---|
US (2) | US6656470B2 (de) |
EP (1) | EP1280521B1 (de) |
AT (1) | ATE299696T1 (de) |
AU (1) | AU2001261433A1 (de) |
DE (1) | DE60112073T2 (de) |
DK (1) | DK1280521T3 (de) |
ES (1) | ES2243497T3 (de) |
HK (1) | HK1049800A1 (de) |
PT (1) | PT1280521E (de) |
WO (1) | WO2001087270A2 (de) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030026782A1 (en) * | 1995-02-07 | 2003-02-06 | Arthur M. Krieg | Immunomodulatory oligonucleotides |
US6207646B1 (en) * | 1994-07-15 | 2001-03-27 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
US6406705B1 (en) * | 1997-03-10 | 2002-06-18 | University Of Iowa Research Foundation | Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant |
US6693086B1 (en) * | 1998-06-25 | 2004-02-17 | National Jewish Medical And Research Center | Systemic immune activation method using nucleic acid-lipid complexes |
US20030022854A1 (en) | 1998-06-25 | 2003-01-30 | Dow Steven W. | Vaccines using nucleic acid-lipid complexes |
EP1280521B1 (de) * | 2000-05-12 | 2005-07-20 | Pharmacia & Upjohn Company LLC | Impfstoffzusammensetzung und verfahren zur herstellung derselben sowie verfahren zur impfung von wirbeltieren |
AU2002233557A1 (en) * | 2001-03-05 | 2002-09-19 | Forinnova As | Immune response potentiation |
FR2823119B1 (fr) * | 2001-04-05 | 2004-02-20 | Seppic Sa | Adjuvant d'immunite contenant un cation metallique complexe et vaccin le contenant |
WO2002094854A2 (en) * | 2001-05-21 | 2002-11-28 | The Brigham And Women's Hospital, Inc. | P.aeruginosa mucoid exopolysaccharide specific binding peptides |
US7119172B2 (en) * | 2001-05-21 | 2006-10-10 | The Brigham And Women's Hospital, Inc. | P. aeruginosa mucoid exopolysaccharide specific binding peptides |
US6678583B2 (en) * | 2001-08-06 | 2004-01-13 | Seminet, Inc. | Robotic storage buffer system for substrate carrier pods |
US7039499B1 (en) * | 2002-08-02 | 2006-05-02 | Seminet Inc. | Robotic storage buffer system for substrate carrier pods |
KR100548925B1 (ko) * | 2002-10-23 | 2006-02-02 | 한미약품 주식회사 | 약물의 경구투여용 서방성 조성물 |
EP2359817B1 (de) * | 2003-03-28 | 2018-01-10 | Sigmoid Pharma Limited | Solide orale Dosierform mit nahtlosen Mikrokapseln |
WO2004087203A2 (en) * | 2003-04-02 | 2004-10-14 | Coley Pharmaceutical Group, Ltd. | Immunostimulatory nucleic acid oil-in-water formulations for topical application |
US20050013812A1 (en) * | 2003-07-14 | 2005-01-20 | Dow Steven W. | Vaccines using pattern recognition receptor-ligand:lipid complexes |
US7081227B2 (en) * | 2004-06-07 | 2006-07-25 | The Reagents Of The University Of California | Amphiphilic mediated sample preparation for micro-flow cytometry |
US20060062779A1 (en) * | 2004-09-21 | 2006-03-23 | The Brigham And Women's Hospital, Inc. | Methods and compositions relating to mannuronic acid specific binding peptides |
CA2581764A1 (en) * | 2004-09-27 | 2006-04-06 | Sigmoid Biotechnologies Limited | Minicapsule formulations |
WO2006059846A1 (en) * | 2004-12-01 | 2006-06-08 | Lg Life Sciences, Ltd. | Formulation of sec1 mutated protein and method for formulation of the same |
JP2008526870A (ja) * | 2005-01-05 | 2008-07-24 | フイラデルフイア・ヘルス・アンド・エデユケーシヨン・コーポレーシヨン | 送達ビヒクル、生体作用活性物質およびウイルスワクチン |
US20090238890A1 (en) * | 2006-01-13 | 2009-09-24 | Advanced Bionutrition Corporation | Continuous spray-capture production system |
US9114071B2 (en) | 2007-04-04 | 2015-08-25 | Sigmoid Pharma Limited | Oral pharmaceutical composition |
JP2010527285A (ja) | 2007-04-26 | 2010-08-12 | シグモイド・ファーマ・リミテッド | 複数のミニカプセルの製造 |
EP2073798A2 (de) * | 2007-05-01 | 2009-07-01 | Sigmoid Pharma Limited | Pharmazeutische nimodipin-zusammensetzungen |
US8709827B2 (en) * | 2007-06-28 | 2014-04-29 | Surmodics, Inc. | Polypeptide microparticles |
ES2649112T3 (es) | 2009-05-18 | 2018-01-10 | Sigmoid Pharma Limited | Composición que comprende gotas de aceite |
WO2011018504A2 (en) * | 2009-08-12 | 2011-02-17 | Sigmoid Pharma Limited | Immunomodulatory compositions comprising a polymer matrix and an oil phase |
GB201020032D0 (en) | 2010-11-25 | 2011-01-12 | Sigmoid Pharma Ltd | Composition |
WO2013029033A2 (en) * | 2011-08-25 | 2013-02-28 | Brian Pulliam | Rotavirus preparations with excess calcium ions and high viscosities that ensure vaccine viability at elevated temperatures |
GB201212010D0 (en) | 2012-07-05 | 2012-08-22 | Sigmoid Pharma Ltd | Formulations |
GB201319791D0 (en) | 2013-11-08 | 2013-12-25 | Sigmoid Pharma Ltd | Formulations |
MX2016007356A (es) * | 2013-12-06 | 2016-10-03 | Advanced Bionutrition Corp | Composicion para administracion oral de agentes bioactivos. |
BR112017009510A2 (pt) | 2014-11-07 | 2017-12-19 | Sigmoid Pharma Ltd | composições compreendendo ciclosporina |
WO2017097844A1 (en) * | 2015-12-07 | 2017-06-15 | Schlumberger Norge As | Microsphere compositions and methods for production in oil-based drilling fluids |
GB202205231D0 (en) * | 2022-04-09 | 2022-05-25 | Nasaleze Patents Ltd | Vaccine compositions |
Family Cites Families (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES335314A1 (es) | 1966-01-06 | 1967-12-01 | Ceskoslovenska Akademie Ved | Mejoras introducidas en la preparacion de vehiculos insolubles de sustancias al menos parcialmente solubles, biologicamente activas. |
EG10802A (en) | 1971-02-19 | 1976-10-31 | Bayer Ag | A process for embeding veterinary substances and their protection against the influence of the gastric juice of the rumen |
US4178361A (en) | 1973-09-10 | 1979-12-11 | Union Corporation | Sustained release pharmaceutical composition |
US4220152A (en) | 1978-05-08 | 1980-09-02 | Pfizer Inc. | Delivery system |
US4391909A (en) | 1979-03-28 | 1983-07-05 | Damon Corporation | Microcapsules containing viable tissue cells |
US4352883A (en) | 1979-03-28 | 1982-10-05 | Damon Corporation | Encapsulation of biological material |
US4798786A (en) | 1982-05-06 | 1989-01-17 | Stolle Research And Development Corporation | Living cells encapsulated in crosslinked protein |
CA1196862A (en) | 1983-06-01 | 1985-11-19 | Anthony M.F. Sun | Microencapsulation of living tissue and cells |
US4806355A (en) | 1983-06-06 | 1989-02-21 | Connaught Laboratories Limited | Microencapsulation of living tissue and cells |
US4689293A (en) | 1983-06-06 | 1987-08-25 | Connaught Laboratories Limited | Microencapsulation of living tissue and cells |
GB8326633D0 (en) | 1983-08-04 | 1983-11-09 | Unilever Plc | Compositions |
US4803168A (en) | 1983-09-01 | 1989-02-07 | Damon Biotech, Inc. | Microencapsulation with polymers |
GB8500121D0 (en) | 1985-01-03 | 1985-02-13 | Connaught Lab | Microencapsulation of living cells |
US4873090A (en) | 1985-03-27 | 1989-10-10 | Broncostat Pty. Limited | Non-adjuvenated vaccine |
US4780315A (en) | 1985-11-25 | 1988-10-25 | Eastman Kodak Company | Rumen-stable pellets |
US5075109A (en) | 1986-10-24 | 1991-12-24 | Southern Research Institute | Method of potentiating an immune response |
NL8701548A (nl) * | 1987-07-01 | 1989-02-01 | Tno | Polymeer netwerk, werkwijze voor het bereiden daarvan alsmede, de toepassing daarvan voor het bekleden en/of impregneren of voor het vervaardigen van ooglenzen, alsmede gevormd voortbrengsel, geheel of ten dele bestaande uit een dergelijk polymeer netwerk. |
US4792452A (en) * | 1987-07-28 | 1988-12-20 | E. R. Squibb & Sons, Inc. | Controlled release formulation |
US4808404A (en) | 1988-01-11 | 1989-02-28 | A. H. Robins Company, Inc. | Live vaccine for coccidiosis utilizing coccidial sporozoites |
JPH01313437A (ja) | 1988-06-14 | 1989-12-18 | Nippon Seibutsu Kagaku Kenkyusho | 飼料内投与用の粒子状生ワクチン及びその製法並びに鶏コクシジウム症生ワクチン |
FR2683147B1 (fr) | 1991-10-30 | 1995-06-23 | Maingault Philippe | Systeme vehicule de principe actif permettant l'administration voie orale chez les poissons et crustaces. |
US5352448A (en) | 1992-07-20 | 1994-10-04 | Purdue Research Foundatioin | Oral administration of antigens |
BR9407397A (pt) | 1993-07-12 | 1996-11-05 | Virus Res Inst | Vacinas microencapsuladas em hidrogel |
US5674495A (en) | 1995-02-27 | 1997-10-07 | Purdue Research Foundation | Alginate-based vaccine compositions |
US6214331B1 (en) * | 1995-06-06 | 2001-04-10 | C. R. Bard, Inc. | Process for the preparation of aqueous dispersions of particles of water-soluble polymers and the particles obtained |
US6656508B2 (en) | 1997-04-17 | 2003-12-02 | Amgen Inc. | Sustained-release alginate gels |
KR20010003853A (ko) * | 1999-06-25 | 2001-01-15 | 박호군 | 경구용 백신으로 사용할 수 있는 알긴산염 마이크로스피어 및그 제조방법 |
EP1280521B1 (de) * | 2000-05-12 | 2005-07-20 | Pharmacia & Upjohn Company LLC | Impfstoffzusammensetzung und verfahren zur herstellung derselben sowie verfahren zur impfung von wirbeltieren |
-
2001
- 2001-05-11 EP EP01935330A patent/EP1280521B1/de not_active Expired - Lifetime
- 2001-05-11 AT AT01935330T patent/ATE299696T1/de not_active IP Right Cessation
- 2001-05-11 US US09/853,919 patent/US6656470B2/en not_active Expired - Fee Related
- 2001-05-11 DE DE60112073T patent/DE60112073T2/de not_active Expired - Fee Related
- 2001-05-11 ES ES01935330T patent/ES2243497T3/es not_active Expired - Lifetime
- 2001-05-11 PT PT01935330T patent/PT1280521E/pt unknown
- 2001-05-11 AU AU2001261433A patent/AU2001261433A1/en not_active Abandoned
- 2001-05-11 DK DK01935330T patent/DK1280521T3/da active
- 2001-05-11 WO PCT/US2001/015235 patent/WO2001087270A2/en active IP Right Grant
-
2003
- 2003-03-18 HK HK03101999A patent/HK1049800A1/xx not_active IP Right Cessation
- 2003-11-10 US US10/705,660 patent/US7160544B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP1280521B1 (de) | 2005-07-20 |
US6656470B2 (en) | 2003-12-02 |
AU2001261433A1 (en) | 2001-11-26 |
WO2001087270A2 (en) | 2001-11-22 |
WO2001087270A3 (en) | 2002-05-16 |
HK1049800A1 (en) | 2003-05-30 |
PT1280521E (pt) | 2005-10-31 |
US20020009457A1 (en) | 2002-01-24 |
ES2243497T3 (es) | 2005-12-01 |
EP1280521A2 (de) | 2003-02-05 |
WO2001087270B1 (en) | 2002-08-15 |
US20040071727A1 (en) | 2004-04-15 |
DK1280521T3 (da) | 2005-08-08 |
DE60112073T2 (de) | 2006-04-20 |
US7160544B2 (en) | 2007-01-09 |
ATE299696T1 (de) | 2005-08-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |