CL2015001068A1 - Inhibidores heteroarilo de pde4 - Google Patents
Inhibidores heteroarilo de pde4Info
- Publication number
- CL2015001068A1 CL2015001068A1 CL2015001068A CL2015001068A CL2015001068A1 CL 2015001068 A1 CL2015001068 A1 CL 2015001068A1 CL 2015001068 A CL2015001068 A CL 2015001068A CL 2015001068 A CL2015001068 A CL 2015001068A CL 2015001068 A1 CL2015001068 A1 CL 2015001068A1
- Authority
- CL
- Chile
- Prior art keywords
- pde4
- inhibitors
- heteroaryl inhibitors
- heteroaryl
- function
- Prior art date
Links
- 239000003112 inhibitor Substances 0.000 title abstract 2
- 101100296720 Dictyostelium discoideum Pde4 gene Proteins 0.000 title 1
- 125000001072 heteroaryl group Chemical group 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/027—Organoboranes and organoborohydrides
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
COMPUESTOS HETEROARILO BICICLO SUSTITUIDOS, INHIBIDORES DE FOSFODOESTERASA 4 (PDE4); COMPOSICION FARMACEUTICA; METODO DE TRATAMIENTO; METODO DE MODULACION DE UNA FUNCION MEDIADA POR PDE4; METODO PARA INHIBIR PDE4; Y USO PARA TRATAR DEPERSION, DEPRESION SECUNDARIA A UN CUADRO CLINICO Y PARA MODULAR UNA FUNCION MEDIADA POR PDE4.
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