CL2012003421A1 - Compuestos derivados de 3-amino-n-(4-carbamoilpiridin-3-il)(aril/heteroaril)-2-carboxamida; procedimiento de preparacion; composicion farmaceutica que los comprende; y su uso en el tratamiento de una enfermedad del snc, oncologica, entre otras. pct fase nacional - Google Patents
Compuestos derivados de 3-amino-n-(4-carbamoilpiridin-3-il)(aril/heteroaril)-2-carboxamida; procedimiento de preparacion; composicion farmaceutica que los comprende; y su uso en el tratamiento de una enfermedad del snc, oncologica, entre otras. pct fase nacionalInfo
- Publication number
- CL2012003421A1 CL2012003421A1 CL2012003421A CL2012003421A CL2012003421A1 CL 2012003421 A1 CL2012003421 A1 CL 2012003421A1 CL 2012003421 A CL2012003421 A CL 2012003421A CL 2012003421 A CL2012003421 A CL 2012003421A CL 2012003421 A1 CL2012003421 A1 CL 2012003421A1
- Authority
- CL
- Chile
- Prior art keywords
- carbamoylpyridin
- carboxamide
- heteroaryl
- aryl
- disease
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Diabetes (AREA)
- Addiction (AREA)
- Psychology (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Compuestos derivados de 3-amino-n-(4-carbamoilpiridin-3-il)(aril/heteroaril)-2-carboxamida; procedimiento de preparación; composición farmacéutica; y su uso para el tratamiento o profilaxis de trastornos psicótico, esquizofrenia, enfermedad de Parkinson, trastornos bipolares, tumores sólidos, Hungtinton, entre otros.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP10165427 | 2010-06-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2012003421A1 true CL2012003421A1 (es) | 2013-07-26 |
Family
ID=44483879
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2012003421A CL2012003421A1 (es) | 2010-06-09 | 2012-12-05 | Compuestos derivados de 3-amino-n-(4-carbamoilpiridin-3-il)(aril/heteroaril)-2-carboxamida; procedimiento de preparacion; composicion farmaceutica que los comprende; y su uso en el tratamiento de una enfermedad del snc, oncologica, entre otras. pct fase nacional |
Country Status (24)
Country | Link |
---|---|
US (1) | US8703768B2 (es) |
EP (1) | EP2580207B1 (es) |
JP (1) | JP5940523B2 (es) |
KR (1) | KR101757959B1 (es) |
CN (1) | CN102947292B (es) |
AR (1) | AR081649A1 (es) |
BR (1) | BR112012031343A2 (es) |
CA (1) | CA2799022A1 (es) |
CL (1) | CL2012003421A1 (es) |
CO (1) | CO6620065A2 (es) |
CR (1) | CR20120594A (es) |
EA (1) | EA022075B1 (es) |
EC (1) | ECSP12012330A (es) |
HK (1) | HK1178900A1 (es) |
IL (1) | IL223069A0 (es) |
MA (1) | MA34340B1 (es) |
MX (1) | MX2012013907A (es) |
NZ (1) | NZ603230A (es) |
PE (1) | PE20130279A1 (es) |
SG (1) | SG185655A1 (es) |
TW (1) | TW201202221A (es) |
UA (1) | UA108105C2 (es) |
WO (1) | WO2011154327A1 (es) |
ZA (1) | ZA201209119B (es) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2011119217A (ru) * | 2008-10-14 | 2012-11-27 | Актелион Фармасьютикалз Лтд | Производные фенетиламида и их гетероциклические аналоги |
KR101464060B1 (ko) | 2010-04-07 | 2014-11-20 | 에프. 호프만-라 로슈 아게 | 피라졸-4-일-헤테로사이클릴-카복사마이드 화합물 및 사용 방법 |
KR20140009372A (ko) | 2011-02-18 | 2014-01-22 | 알러간, 인코포레이티드 | 포스포다이에스테라제 10(pde10a)의 억제제로서의 치환된 6,7-다이알콕시-3-아이소퀴놀리놀 유도체 |
SG2014012579A (en) | 2011-09-27 | 2014-04-28 | Hoffmann La Roche | Pyrazol-4-yl-heterocyclyl-carboxamide compounds and methods of use |
EP2712862A1 (en) * | 2012-09-28 | 2014-04-02 | Splicos | New anti-invasive compounds |
EP2903613B1 (en) * | 2012-10-08 | 2017-11-22 | Merck Sharp & Dohme Corp. | Pyrazole derivatives useful as inhibitors of irak4 activity |
WO2014071044A1 (en) | 2012-11-01 | 2014-05-08 | Allergan, Inc. | Substituted 6,7-dialkoxy-3-isoquinoline derivatives as inhibitors of phosphodiesterase 10 (pde10a) |
EP2963037B1 (en) | 2013-02-27 | 2019-03-27 | Mochida Pharmaceutical Co., Ltd. | Novel pyrazole derivative |
DK2991983T3 (en) * | 2013-04-29 | 2017-05-08 | Hoffmann La Roche | 2-PHENYL OR 2-HETARYLIMIDAZOLE [1,2-a] PYRIDINE DERIVATIVES |
GB201316600D0 (en) * | 2013-09-18 | 2013-10-30 | Redx Pharma Ltd | Agricultural chemicals |
US20160264536A1 (en) * | 2013-10-23 | 2016-09-15 | Takeda Pharmaceutical Company Limited | Heterocyclic compound |
US9200016B2 (en) | 2013-12-05 | 2015-12-01 | Allergan, Inc. | Substituted 6, 7-dialkoxy-3-isoquinoline derivatives as inhibitors of phosphodiesterase 10 (PDE 10A) |
US10420341B2 (en) * | 2015-01-30 | 2019-09-24 | Basf Se | Herbicidal phenylpyrimidines |
US9624246B2 (en) * | 2015-02-06 | 2017-04-18 | Merck Patent Gmbh | Pyridazinone macrocycles as IRAK inhibitors and uses thereof |
CN104610189A (zh) * | 2015-02-10 | 2015-05-13 | 佛山市赛维斯医药科技有限公司 | 一类含环丙基脒结构sglt2/sglt1双靶点抑制剂及用途 |
CN104974075A (zh) * | 2015-08-07 | 2015-10-14 | 新秀化学(烟台)有限公司 | 一种n, n-二(2,2,6,6-四甲基-4-哌啶基) -1,3-苯二甲酰胺的制备方法 |
CA3030167A1 (en) * | 2016-07-12 | 2018-01-18 | Revolution Medicines, Inc. | 2,5-disubstituted 3-methyl pyrazines and 2,5,6-trisubstituted 3-methyl pyrazines as allosteric shp2 inhibitors |
AU2017302983A1 (en) | 2016-07-26 | 2019-01-03 | Basf Se | Herbicidal pyrimidine compounds |
WO2018019767A1 (en) | 2016-07-27 | 2018-02-01 | Basf Se | Herbicidal pyridine compounds |
CN109475127A (zh) | 2016-07-27 | 2019-03-15 | 巴斯夫欧洲公司 | 除草的嘧啶化合物 |
EP3490380A1 (en) | 2016-07-28 | 2019-06-05 | Basf Se | Herbicidal pyrimidine compounds |
IL296456A (en) | 2017-01-23 | 2022-11-01 | Revolution Medicines Inc | Bicyclics as allosteric shp2 inhibitors |
EP4230623A3 (en) | 2017-01-23 | 2023-10-11 | Revolution Medicines, Inc. | Pyridine compounds as allosteric shp2 inhibitors |
EP3694848A1 (en) | 2017-10-12 | 2020-08-19 | Revolution Medicines, Inc. | Pyridine, pyrazine, and triazine compounds as allosteric shp2 inhibitors |
EP3724189B1 (en) | 2017-12-15 | 2023-10-04 | Revolution Medicines, Inc. | Polycyclic compounds as allosteric shp2 inhibitors |
WO2019121352A1 (en) | 2017-12-20 | 2019-06-27 | Basf Se | Herbicidal pyrimidine compounds |
WO2019121374A1 (en) | 2017-12-20 | 2019-06-27 | Basf Se | Herbicidal pyrimidine compounds |
KR20200112815A (ko) * | 2017-12-20 | 2020-10-05 | 피아이 인더스트리스 엘티디. | 살충제로서의 피라졸로피리딘-디아미드 용도 및 그의 제조 방법 |
EP3853219B1 (de) | 2018-09-19 | 2023-07-12 | Bayer Aktiengesellschaft | Herbizid wirksame substituierte phenylpyrimidinhydrazide |
US20210387966A1 (en) * | 2018-11-02 | 2021-12-16 | Merck Sharp & Dohme Corp. | 2-amino-n-heteroaryl-nicotinamides as nav1.8 inhibitors |
EP4052760B1 (en) | 2019-10-31 | 2024-03-13 | FUJIFILM Corporation | Pyrazine derivative or salt thereof, and use of same |
JPWO2022025174A1 (es) | 2020-07-30 | 2022-02-03 | ||
WO2022103960A1 (en) | 2020-11-13 | 2022-05-19 | Inipharm, Inc. | Dichlorophenol hsd17b13 inhibitors and uses thereof |
EP4319872A1 (en) * | 2021-04-05 | 2024-02-14 | Inipharm, Inc. | Thiazole/isothiazole hsd17b13 inhibitors and uses thereof |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9910079D0 (en) | 1999-05-01 | 1999-06-30 | Smithkline Beecham Plc | Novel compounds |
EP1193261A1 (en) | 2000-10-02 | 2002-04-03 | Warner-Lambert Company | New thiadiazoles and their use as phosphodiesterase-7 inhibitors |
EP1651251A4 (en) | 2003-07-31 | 2008-06-18 | Bayer Pharmaceuticals Corp | METHOD FOR THE TREATMENT OF DIABETES AND RELATED DISEASES USING PDE 10A INHIBITORS |
US7163937B2 (en) | 2003-08-21 | 2007-01-16 | Bristol-Myers Squibb Company | Cyclic derivatives as modulators of chemokine receptor activity |
CN1933838A (zh) | 2004-02-12 | 2007-03-21 | 默克公司 | 作为代谢型谷氨酸受体-5调节剂的联吡啶酰胺 |
US20060199828A1 (en) | 2005-03-04 | 2006-09-07 | Georg Jaeschke | Pyrazine-2-carboxyamide derivatives |
ES2476840T3 (es) * | 2005-03-04 | 2014-07-15 | F. Hoffmann-La Roche Ag | Derivados de piridina-2-carboxamida como antagonistas de MGLUR5 |
AR057987A1 (es) | 2005-11-24 | 2008-01-09 | Astrazeneca Ab | Compuestos agonistas de cb1 (receptor cannabinoide) |
EP2132177B1 (en) | 2007-03-01 | 2013-07-17 | Novartis AG | Pim kinase inhibitors and methods of their use |
WO2009026241A1 (en) | 2007-08-23 | 2009-02-26 | Kalypsys, Inc. | Heterocyclic modulators of tgr5 |
US8470820B2 (en) | 2010-01-22 | 2013-06-25 | Hoffman-La Roche Inc. | Nitrogen-containing heteroaryl derivatives |
-
2011
- 2011-06-02 US US13/151,301 patent/US8703768B2/en active Active
- 2011-06-06 CN CN201180027950.8A patent/CN102947292B/zh not_active Expired - Fee Related
- 2011-06-06 EA EA201291282A patent/EA022075B1/ru not_active IP Right Cessation
- 2011-06-06 SG SG2012085015A patent/SG185655A1/en unknown
- 2011-06-06 JP JP2013513638A patent/JP5940523B2/ja not_active Expired - Fee Related
- 2011-06-06 NZ NZ603230A patent/NZ603230A/xx not_active IP Right Cessation
- 2011-06-06 MX MX2012013907A patent/MX2012013907A/es active IP Right Grant
- 2011-06-06 EP EP11723077.1A patent/EP2580207B1/en not_active Not-in-force
- 2011-06-06 MA MA35502A patent/MA34340B1/fr unknown
- 2011-06-06 BR BR112012031343A patent/BR112012031343A2/pt not_active Application Discontinuation
- 2011-06-06 KR KR1020137000568A patent/KR101757959B1/ko active IP Right Grant
- 2011-06-06 UA UAA201214955A patent/UA108105C2/ru unknown
- 2011-06-06 CA CA2799022A patent/CA2799022A1/en not_active Abandoned
- 2011-06-06 PE PE2012002298A patent/PE20130279A1/es not_active Application Discontinuation
- 2011-06-06 WO PCT/EP2011/059234 patent/WO2011154327A1/en active Application Filing
- 2011-06-07 AR ARP110101963A patent/AR081649A1/es unknown
- 2011-06-08 TW TW100120008A patent/TW201202221A/zh unknown
-
2012
- 2012-10-26 CO CO12192367A patent/CO6620065A2/es active IP Right Grant
- 2012-11-15 IL IL223069A patent/IL223069A0/en unknown
- 2012-11-26 CR CR20120594A patent/CR20120594A/es unknown
- 2012-12-03 ZA ZA2012/09119A patent/ZA201209119B/en unknown
- 2012-12-05 CL CL2012003421A patent/CL2012003421A1/es unknown
- 2012-12-07 EC ECSP12012330 patent/ECSP12012330A/es unknown
-
2013
- 2013-05-17 HK HK13105859.4A patent/HK1178900A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
PE20130279A1 (es) | 2013-03-08 |
WO2011154327A1 (en) | 2011-12-15 |
TW201202221A (en) | 2012-01-16 |
KR20130112858A (ko) | 2013-10-14 |
BR112012031343A2 (pt) | 2016-11-01 |
EP2580207B1 (en) | 2017-09-27 |
EA201291282A1 (ru) | 2013-06-28 |
US8703768B2 (en) | 2014-04-22 |
CA2799022A1 (en) | 2011-12-15 |
NZ603230A (en) | 2013-09-27 |
IL223069A0 (en) | 2013-02-03 |
SG185655A1 (en) | 2012-12-28 |
MX2012013907A (es) | 2012-12-17 |
EA022075B1 (ru) | 2015-10-30 |
CR20120594A (es) | 2013-01-03 |
US20110306589A1 (en) | 2011-12-15 |
UA108105C2 (ru) | 2015-03-25 |
JP5940523B2 (ja) | 2016-06-29 |
CN102947292B (zh) | 2015-08-19 |
EP2580207A1 (en) | 2013-04-17 |
AR081649A1 (es) | 2012-10-10 |
CN102947292A (zh) | 2013-02-27 |
ECSP12012330A (es) | 2012-12-28 |
CO6620065A2 (es) | 2013-02-15 |
KR101757959B1 (ko) | 2017-07-14 |
ZA201209119B (en) | 2015-05-27 |
JP2013528193A (ja) | 2013-07-08 |
MA34340B1 (fr) | 2013-06-01 |
HK1178900A1 (en) | 2013-09-19 |
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