CL2015000038A1 - Métodos para preparar triazolopiridinas sustituidas y compuestos intermediarios. - Google Patents

Métodos para preparar triazolopiridinas sustituidas y compuestos intermediarios.

Info

Publication number
CL2015000038A1
CL2015000038A1 CL2015000038A CL2015000038A CL2015000038A1 CL 2015000038 A1 CL2015000038 A1 CL 2015000038A1 CL 2015000038 A CL2015000038 A CL 2015000038A CL 2015000038 A CL2015000038 A CL 2015000038A CL 2015000038 A1 CL2015000038 A1 CL 2015000038A1
Authority
CL
Chile
Prior art keywords
methods
intermediates
preparing substituted
substituted triazolopyridines
triazolopyridines
Prior art date
Application number
CL2015000038A
Other languages
English (en)
Spanish (es)
Inventor
Volker Schulze Dr
Franz-Josef Mais Dr
Original Assignee
Bayer Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Pharma AG filed Critical Bayer Pharma AG
Publication of CL2015000038A1 publication Critical patent/CL2015000038A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CL2015000038A 2012-07-10 2015-01-08 Métodos para preparar triazolopiridinas sustituidas y compuestos intermediarios. CL2015000038A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12175640 2012-07-10
EP12185590 2012-09-24
EP13170585 2013-06-05

Publications (1)

Publication Number Publication Date
CL2015000038A1 true CL2015000038A1 (es) 2015-03-13

Family

ID=48793197

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2015000038A CL2015000038A1 (es) 2012-07-10 2015-01-08 Métodos para preparar triazolopiridinas sustituidas y compuestos intermediarios.

Country Status (24)

Country Link
US (1) US9388177B2 (h)
EP (1) EP2872506A1 (h)
JP (1) JP6238979B2 (h)
KR (1) KR20150040845A (h)
CN (1) CN104603136B (h)
AP (1) AP3778A (h)
AU (1) AU2013289381A1 (h)
BR (1) BR112015000308A2 (h)
CA (1) CA2878481A1 (h)
CL (1) CL2015000038A1 (h)
CO (1) CO7160002A2 (h)
CR (1) CR20150006A (h)
DO (1) DOP2015000007A (h)
EA (1) EA027544B1 (h)
HK (1) HK1206731A1 (h)
IL (1) IL236265A (h)
IN (1) IN2015DN00085A (h)
MX (1) MX2015000348A (h)
NZ (1) NZ703020A (h)
PE (1) PE20150354A1 (h)
PH (1) PH12015500061A1 (h)
SG (1) SG11201408419QA (h)
TN (1) TN2015000008A1 (h)
WO (1) WO2014009219A1 (h)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014195276A1 (en) * 2013-06-07 2014-12-11 Bayer Pharma Aktiengesellschaft Substituted triazolopyridines having activity as mps-1 inhibitors
EP3008062B1 (en) * 2013-06-11 2017-04-05 Bayer Pharma Aktiengesellschaft Prodrug derivatives of substituted triazolopyridines
US20160128988A1 (en) 2013-06-11 2016-05-12 Bayer Pharma Aktiengesellschaft Combinations for the treatment of cancer comprising a mps-1 kinase inhibitor and a mitotic inhibitor
EP3283642B1 (en) 2015-04-17 2023-10-11 Netherlands Translational Research Center Holding B.V. Prognostic biomarkers for ttk inhibitor chemotherapy
TW201800408A (zh) 2016-06-15 2018-01-01 拜耳製藥公司 Mps-1抑制劑

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003030937A1 (en) * 2001-10-05 2003-04-17 Ono Pharmaceutical Co., Ltd. Remedies for stress diseases comprising mitochondrial benzodiazepine receptor antagonists
US20060074102A1 (en) * 2004-05-14 2006-04-06 Kevin Cusack Kinase inhibitors as therapeutic agents
UA89503C2 (uk) * 2004-09-13 2010-02-10 Х. Луннбек А/С Заміщені похідні аніліну
WO2006038116A2 (en) * 2004-10-07 2006-04-13 Warner-Lambert Company Llc Triazolopyridine derivatives as antibacterial agents
US20060194823A1 (en) * 2004-12-22 2006-08-31 Georg Kettschau Sulfonamido-macrocycles as Tie2 inhibitors and the salts thereof, a pharmaceutical composition comprising these compounds, the method of preparing and the use thereof
MX2008015747A (es) * 2006-06-06 2008-12-19 Schering Corp Imidazopirazinas como inhibidores de la proteina quinasa.
EP1870416A1 (en) * 2006-06-21 2007-12-26 Bayer Schering Pharma Aktiengesellschaft Sulphonamido-macrocycles as tie2 inhibitors
BRPI0716239A2 (pt) 2006-08-30 2013-08-13 Cellzome Ltd derivados de triazol como inibidores de cinase
JO3598B1 (ar) * 2006-10-10 2020-07-05 Infinity Discovery Inc الاحماض والاسترات البورونية كمثبطات اميد هيدروليز الحامض الدهني
CN101801966A (zh) 2007-07-18 2010-08-11 诺瓦提斯公司 双环杂芳基化合物和它们作为激酶抑制剂的用途
CA2696200A1 (en) 2007-08-23 2009-02-26 Astrazeneca Ab 2-anilinopurin-8-ones as inhibitors of ttk/mps1 for the treatment of proliferative disorders
KR20100075881A (ko) 2007-08-31 2010-07-05 메르크 세로노 에스. 에이. 트리아졸로피리딘 화합물 및 ａｓｋ 저해제로서 이의 용도
GB0719803D0 (en) 2007-10-10 2007-11-21 Cancer Rec Tech Ltd Therapeutic compounds and their use
GB0724342D0 (en) * 2007-12-13 2008-01-30 Prolysis Ltd Anitbacterial compositions
US8530689B2 (en) * 2008-05-05 2013-09-10 The Trustees Of The University Of Pennsylvania Processes for the preparation of biphenyl compounds
EP2303890A4 (en) * 2008-06-19 2012-04-11 Progenics Pharm Inc INHIBITORS OF PHOSPHATIDYLINOSITE-3-KINASE
PE20120110A1 (es) 2009-02-13 2012-02-20 Fovea Pharmaceuticals [1,2,4]triazolo[1,5-a]piridinas como inhibidores de cinasa
CA2760077A1 (en) 2009-04-29 2010-11-04 Marcus Koppitz Substituted imidazoquinoxalines
WO2010141360A1 (en) * 2009-06-05 2010-12-09 Merck Sharp & Dohme Corp. Biaryl benzotriazole derivatives
WO2010141796A2 (en) * 2009-06-05 2010-12-09 Cephalon, Inc. PREPARATION AND USES OF 1,2,4-TRIAZOLO [1,5a] PYRIDINE DERIVATIVES
JP5728683B2 (ja) 2009-09-04 2015-06-03 バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングＢａｙｅｒ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ ＧｍｂＨ チロシンスレオニンキナーゼ阻害剤としての置換アミノキノキサリン
EP2343294A1 (en) * 2009-11-30 2011-07-13 Bayer Schering Pharma AG Substituted triazolopyridines
EP2343295A1 (en) 2009-11-30 2011-07-13 Bayer Schering Pharma AG Triazolopyridine derivates
EP2343297A1 (en) * 2009-11-30 2011-07-13 Bayer Schering Pharma AG Triazolopyridines
UY33452A (es) * 2010-06-16 2012-01-31 Bayer Schering Pharma Ag Triazolopiridinas sustituidas
WO2012044567A2 (en) * 2010-09-30 2012-04-05 Merck Sharp & Dohme Corp. Imidazole derivatives
EA023766B1 (ru) * 2011-04-21 2016-07-29 Байер Интеллектчуал Проперти Гмбх Триазолопиридины
WO2012160029A1 (en) * 2011-05-23 2012-11-29 Bayer Intellectual Property Gmbh Substituted triazolopyridines
UA112096C2 (uk) * 2011-12-12 2016-07-25 Байєр Інтеллектуал Проперті Гмбх Заміщені триазолопіридини та їх застосування як інгібіторів ttk

Also Published As

Publication number Publication date
MX2015000348A (es) 2015-04-14
IL236265A0 (en) 2015-02-26
JP6238979B2 (ja) 2017-11-29
CO7160002A2 (es) 2015-01-15
PH12015500061A1 (en) 2015-03-02
DOP2015000007A (es) 2015-02-15
CN104603136A (zh) 2015-05-06
CR20150006A (es) 2015-02-16
IN2015DN00085A (h) 2015-05-29
PE20150354A1 (es) 2015-03-21
IL236265A (en) 2017-07-31
NZ703020A (en) 2017-08-25
EA201590116A1 (ru) 2015-07-30
WO2014009219A1 (en) 2014-01-16
AU2013289381A1 (en) 2015-01-22
TN2015000008A1 (en) 2016-06-29
EA027544B1 (ru) 2017-08-31
AP2014008177A0 (en) 2014-12-31
CA2878481A1 (en) 2014-01-16
US20150148542A1 (en) 2015-05-28
US9388177B2 (en) 2016-07-12
BR112015000308A2 (pt) 2017-06-27
EP2872506A1 (en) 2015-05-20
SG11201408419QA (en) 2015-01-29
HK1206731A1 (en) 2016-01-15
JP2015523372A (ja) 2015-08-13
KR20150040845A (ko) 2015-04-15
AP3778A (en) 2016-08-31
CN104603136B (zh) 2017-06-27

Similar Documents

Publication Publication Date Title
CR20140463A (es) Compuestos de heterociclilo como inhibidores de mek
CR20130539A (es) Triazolopiridinas
UY34602A (es) ?Derivados de bencimidazolil- e imidazopiridinil-metilamina?
CR20150370A (es) Compuestos antivirales
UY33943A (es) Derivados espirocíclicos de isoxazolina como agentes antiparasitarios.
UY34836A (es) Nuevo organismos
MX2016004933A (es) Inhibidores de pirimidina del fgfr4.
UY34472A (es) Derivados modificados de 4-fenil-piridina
UY34654A (es) Inhibidores de la beta-secretasa
CO6980657A2 (es) Triazolopiridinas sustituidas
UY33977A (es) Híbrido de pigmento autoaglutinante.
UY34467A (es) Procedimiento para la preparación de 5-fluoro-1h-pirazolopiridinas sustituidas
DOP2015000059A (es) Amino-quinolinas como inhibidores de cinasa
DOP2015000060A (es) Profármacos de aminoquinazolina inhibidora de cinasa
UY33976A (es) Derivados de pirazolo-pirimidina.
CR20140495A (es) 5-amino[1,4]thiazines como inhibidores de bace1
UY4181Q (es) Taza
MX2020011641A (es) Proceso novedoso para la preparacion de pirrolidina-dionas espiroheterociclicas.
UY34612A (es) ?procedimiento para la preparación de derivados de isoxazolina azetidina quirales como agentes antiparasitarios?.
MX369290B (es) Inhibidores de fbx03.
CL2015000038A1 (es) Métodos para preparar triazolopiridinas sustituidas y compuestos intermediarios.
ECSP13012914A (es) Síntesis de derivados de 2-carboxamida-cicloamino-urea
GT201200328A (es) Intermedios de agomelatina y método de preparación de éstos
UY34286A (es) Diagnóstico de vacuna mejorado
BR112014028443A2 (pt) composição estéril.