CL2014001244A1 - Uso de una composicion farmaceutica que comprende un derivado de 4-pregenen-11beta-17-21-triol-3,20-diona para tratar una condicion ocular tal como presion intraocular elevada, glaucoma, uveitis, degeneracion macular, retinopatia diabetica, rosacea ocular, desprendimiento de retina, entre otras. - Google Patents

Uso de una composicion farmaceutica que comprende un derivado de 4-pregenen-11beta-17-21-triol-3,20-diona para tratar una condicion ocular tal como presion intraocular elevada, glaucoma, uveitis, degeneracion macular, retinopatia diabetica, rosacea ocular, desprendimiento de retina, entre otras.

Info

Publication number
CL2014001244A1
CL2014001244A1 CL2014001244A CL2014001244A CL2014001244A1 CL 2014001244 A1 CL2014001244 A1 CL 2014001244A1 CL 2014001244 A CL2014001244 A CL 2014001244A CL 2014001244 A CL2014001244 A CL 2014001244A CL 2014001244 A1 CL2014001244 A1 CL 2014001244A1
Authority
CL
Chile
Prior art keywords
ocular
pregenen
11beta
uveitis
triol
Prior art date
Application number
CL2014001244A
Other languages
English (en)
Inventor
Jeffrey L Edelman
Alissar Nehme
Original Assignee
Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47179019&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2014001244(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Allergan Inc filed Critical Allergan Inc
Publication of CL2014001244A1 publication Critical patent/CL2014001244A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
CL2014001244A 2011-11-11 2014-05-12 Uso de una composicion farmaceutica que comprende un derivado de 4-pregenen-11beta-17-21-triol-3,20-diona para tratar una condicion ocular tal como presion intraocular elevada, glaucoma, uveitis, degeneracion macular, retinopatia diabetica, rosacea ocular, desprendimiento de retina, entre otras. CL2014001244A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161558775P 2011-11-11 2011-11-11

Publications (1)

Publication Number Publication Date
CL2014001244A1 true CL2014001244A1 (es) 2014-11-14

Family

ID=47179019

Family Applications (2)

Application Number Title Priority Date Filing Date
CL2014001244A CL2014001244A1 (es) 2011-11-11 2014-05-12 Uso de una composicion farmaceutica que comprende un derivado de 4-pregenen-11beta-17-21-triol-3,20-diona para tratar una condicion ocular tal como presion intraocular elevada, glaucoma, uveitis, degeneracion macular, retinopatia diabetica, rosacea ocular, desprendimiento de retina, entre otras.
CL2014001243A CL2014001243A1 (es) 2011-11-11 2014-05-12 Compuestos derivados de 4-pregenen-11beta-17-21-triol-3,20-diona, moduladores de los receptores glucocorticoide o mineralocorticoide; composicion farmaceutica; metodo de tratamiento de condiciones oculares tales como ojo seco, blefaritis, rosacea ocular, uveitis y degeneracion macular entre otras.

Family Applications After (1)

Application Number Title Priority Date Filing Date
CL2014001243A CL2014001243A1 (es) 2011-11-11 2014-05-12 Compuestos derivados de 4-pregenen-11beta-17-21-triol-3,20-diona, moduladores de los receptores glucocorticoide o mineralocorticoide; composicion farmaceutica; metodo de tratamiento de condiciones oculares tales como ojo seco, blefaritis, rosacea ocular, uveitis y degeneracion macular entre otras.

Country Status (24)

Country Link
US (7) US8906892B2 (es)
EP (2) EP2776041A1 (es)
JP (2) JP6158201B2 (es)
KR (2) KR102049615B1 (es)
CN (2) CN104203247B (es)
AR (1) AR088846A1 (es)
AU (3) AU2012335590B2 (es)
BR (2) BR112014011341A2 (es)
CA (3) CA2855929C (es)
CL (2) CL2014001244A1 (es)
CO (2) CO6970598A2 (es)
ES (1) ES2806603T3 (es)
HK (2) HK1200367A1 (es)
IL (2) IL232535B (es)
IN (2) IN2014CN03919A (es)
MX (3) MX363669B (es)
MY (2) MY182222A (es)
PH (2) PH12014501078A1 (es)
RU (2) RU2683775C2 (es)
SG (3) SG11201402225RA (es)
TW (1) TWI584809B (es)
UA (2) UA116622C2 (es)
WO (2) WO2013071010A1 (es)
ZA (2) ZA201403431B (es)

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TWI643853B (zh) 2013-02-27 2018-12-11 阿爾米雷爾有限公司 同時具有β2腎上腺素受體促效劑和M3毒蕈鹼受體拮抗劑活性之2-氨基-1-羥乙基-8-羥基喹啉-2(1H)-酮衍生物之鹽類
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Publication number Publication date
HK1200366A1 (en) 2015-08-07
BR112014011333B1 (pt) 2020-04-28
CA2855929A1 (en) 2013-05-16
KR20140095549A (ko) 2014-08-01
MX2019006877A (es) 2019-08-22
US20150005519A1 (en) 2015-01-01
CA2991883C (en) 2020-03-10
IL232535A0 (en) 2014-06-30
CN104203247A (zh) 2014-12-10
AU2018200436A1 (en) 2018-02-08
CA2991883A1 (en) 2013-05-16
US20170182062A1 (en) 2017-06-29
MY182222A (en) 2021-01-18
CL2014001243A1 (es) 2014-11-28
SG11201402247PA (en) 2014-06-27
CN104185472B (zh) 2017-06-13
US10493082B2 (en) 2019-12-03
MY172227A (en) 2019-11-18
ES2806603T3 (es) 2021-02-18
PH12014501078B1 (en) 2014-07-28
AU2012335589A1 (en) 2014-05-29
MX365859B (es) 2019-06-18
US20180147217A1 (en) 2018-05-31
US8906892B2 (en) 2014-12-09
MX363669B (es) 2019-03-29
WO2013071009A1 (en) 2013-05-16
US20150057258A1 (en) 2015-02-26
BR112014011333A2 (pt) 2017-05-02
US8865691B2 (en) 2014-10-21
AU2012335590A1 (en) 2014-05-29
MX2014005679A (es) 2014-12-10
NZ624919A (en) 2016-10-28
RU2688159C2 (ru) 2019-05-20
CN104203247B (zh) 2017-06-06
JP6158201B2 (ja) 2017-07-05
HK1200367A1 (en) 2015-08-07
AR088846A1 (es) 2014-07-10
CO6970598A2 (es) 2014-06-13
RU2683775C2 (ru) 2019-04-02
US10188667B2 (en) 2019-01-29
JP6216719B2 (ja) 2017-10-18
JP2014533274A (ja) 2014-12-11
IN2014CN03919A (es) 2015-09-04
SG10201603766PA (en) 2016-07-28
PH12014501079A1 (en) 2014-07-28
EP2776040A1 (en) 2014-09-17
US9433631B2 (en) 2016-09-06
SG11201402225RA (en) 2014-06-27
CA2855290A1 (en) 2013-05-16
EP2776040B1 (en) 2020-04-22
TWI584809B (zh) 2017-06-01
UA116622C2 (uk) 2018-04-25
TW201325596A (zh) 2013-07-01
BR112014011341A2 (pt) 2017-05-02
KR20140095548A (ko) 2014-08-01
CN104185472A (zh) 2014-12-03
WO2013071010A1 (en) 2013-05-16
AU2012335589B2 (en) 2017-08-31
US9717743B2 (en) 2017-08-01
RU2014123472A (ru) 2015-12-20
US20130123226A1 (en) 2013-05-16
CO6970609A2 (es) 2014-06-13
PH12014501079B1 (en) 2014-07-28
UA111867C2 (uk) 2016-06-24
IL232535B (en) 2019-09-26
US20130123223A1 (en) 2013-05-16
KR102049615B1 (ko) 2019-11-28
CA2855290C (en) 2017-02-28
US20190365786A1 (en) 2019-12-05
MX2014005678A (es) 2014-12-10
IN2014CN03903A (es) 2015-10-16
PH12014501078A1 (en) 2014-07-28
AU2012335590B2 (en) 2017-10-19
AU2018200436B2 (en) 2019-10-24
ZA201403430B (en) 2016-05-25
RU2014123471A (ru) 2015-12-20
JP2014533275A (ja) 2014-12-11
ZA201403431B (en) 2016-05-25
NZ624920A (en) 2017-06-30
IL232534A0 (en) 2014-06-30
EP2776041A1 (en) 2014-09-17
CA2855929C (en) 2018-03-27

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