CL2013003274A1 - Proceso para enrollar un soporte de colágeno donde se humedece al menos parte de dicho soporte de colágeno antes de enrollarlo y el cual es sostenido por un dispositivo de soporte para después secar. - Google Patents

Proceso para enrollar un soporte de colágeno donde se humedece al menos parte de dicho soporte de colágeno antes de enrollarlo y el cual es sostenido por un dispositivo de soporte para después secar.

Info

Publication number
CL2013003274A1
CL2013003274A1 CL2013003274A CL2013003274A CL2013003274A1 CL 2013003274 A1 CL2013003274 A1 CL 2013003274A1 CL 2013003274 A CL2013003274 A CL 2013003274A CL 2013003274 A CL2013003274 A CL 2013003274A CL 2013003274 A1 CL2013003274 A1 CL 2013003274A1
Authority
CL
Chile
Prior art keywords
collagen
support
collagen support
winding
rolled
Prior art date
Application number
CL2013003274A
Other languages
English (en)
Inventor
Wolfgang Schönhofer
Pernille Dybendal Pedersen
Poul Bertelsen
Henrik Braender
Ingrid Blanka
Henrik Neuschäfer LARSEN
Original Assignee
Takeda As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda As filed Critical Takeda As
Publication of CL2013003274A1 publication Critical patent/CL2013003274A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F13/02Adhesive bandages or dressings
    • A61F13/0276Apparatus or processes for manufacturing adhesive dressings or bandages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/438The ring being spiro-condensed with carbocyclic or heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36Blood coagulation or fibrinolysis factors
    • A61K38/363Fibrinogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482Serine endopeptidases (3.4.21)
    • A61K38/4833Thrombin (3.4.21.5)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007Drug-containing films, membranes or sheets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/043Mixtures of macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04Macromolecular materials
    • A61L31/041Mixtures of macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10Laxatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10Spiro-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/10Spiro-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/0057Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Surgery (AREA)
  • Hematology (AREA)
  • Manufacturing & Machinery (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Inorganic Chemistry (AREA)
  • Otolaryngology (AREA)
  • Hospice & Palliative Care (AREA)
  • Nutrition Science (AREA)
  • Diabetes (AREA)
  • Materials For Medical Uses (AREA)
  • Peptides Or Proteins (AREA)
  • Prostheses (AREA)

Abstract

Se divulga un proceso para enrollar un soporte de colágeno, donde el soporte de colágeno comprende (i) una capa de colágeno y (ii) una capa de recubrimiento que comprende fibrinógeno y trombina, comprendiendo dicho procedimiento las etapas secuenciales de: - Humedecer al menos parte de dicho soporte de colágeno, - Enrollar dicho soporte de colágeno sujetando el soporte de colágeno entre un par de miembros alargados y girar el par de miembros alargados alrededor de un eje paralelo a una extensión longitudinal de los miembros alargados con el fin de enrollar el soporte de colágeno en los miembros, mientras el soporte de colágeno está soportado por un dispositivo de soporte, - Secar el soporte de colágeno enrollado, Proporcionando de este modo un soporte de colágeno enrollado de forma estable. También se divulga un soporte de colágeno enrollado que comprende una capa de colágeno y una capa de revestimiento encima de la capa de colágeno, la capa de recubrimiento que comprende trombina y fibrinógeno que tiene la forma de un elemento alargado con un número de bobinados del soporte de colágeno alrededor del eje longitudinal del elemento alargado y al menos el bobinado exterior (s) siendo orientado de tal manera que la capa de recubrimiento constituye la superficie exterior de cada uno de dichos bobinados exterior (s), donde el soporte de colágeno enrollado es de forma estable y define un soporte de colágeno en una configuración enrollada, donde dichos bobinados exteriores(s) avanzan a lo largo de una espiral en una sección transversal del soporte de colágeno.
CL2013003274A 2011-05-24 2013-11-14 Proceso para enrollar un soporte de colágeno donde se humedece al menos parte de dicho soporte de colágeno antes de enrollarlo y el cual es sostenido por un dispositivo de soporte para después secar. CL2013003274A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP11167379 2011-05-24

Publications (1)

Publication Number Publication Date
CL2013003274A1 true CL2013003274A1 (es) 2014-06-20

Family

ID=44692373

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2013003274A CL2013003274A1 (es) 2011-05-24 2013-11-14 Proceso para enrollar un soporte de colágeno donde se humedece al menos parte de dicho soporte de colágeno antes de enrollarlo y el cual es sostenido por un dispositivo de soporte para después secar.

Country Status (37)

Country Link
US (2) US9814686B2 (es)
EP (2) EP2713972B9 (es)
JP (1) JP6025824B2 (es)
KR (1) KR101833035B1 (es)
CN (1) CN103702645B (es)
AP (1) AP2013007327A0 (es)
AR (1) AR086557A1 (es)
AU (1) AU2012261339B2 (es)
BR (1) BR112013029709B1 (es)
CA (1) CA2837117C (es)
CL (1) CL2013003274A1 (es)
CO (1) CO6862131A2 (es)
CY (1) CY1119313T1 (es)
DK (2) DK3243489T3 (es)
EA (1) EA028878B1 (es)
ES (2) ES2871064T3 (es)
GE (1) GEP201706715B (es)
HR (1) HRP20171424T1 (es)
HU (1) HUE032689T4 (es)
IL (1) IL229446A (es)
LT (1) LT2713972T (es)
MD (1) MD4471C1 (es)
ME (1) ME02830B (es)
MX (1) MX355925B (es)
MY (1) MY185054A (es)
PE (1) PE20141037A1 (es)
PL (2) PL2713972T3 (es)
PT (1) PT2713972T (es)
RS (1) RS56367B1 (es)
SA (1) SA112330549B1 (es)
SI (1) SI2713972T1 (es)
TN (1) TN2013000391A1 (es)
TW (1) TWI552774B (es)
UA (1) UA113959C2 (es)
UY (1) UY34096A (es)
WO (1) WO2012159635A1 (es)
ZA (1) ZA201307060B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK3243489T3 (da) 2011-05-24 2021-05-10 Takeda As Oprullet kollagenbærer
BR112014028836B1 (pt) * 2012-05-24 2021-06-29 Takeda As Embalagem para armazenar um portador de colágeno em espiral com forma estável
JP6242873B2 (ja) 2012-05-24 2017-12-06 タケダ エイエスTakeda AS コイル状コラーゲンキャリアを提供する装置およびプロセス
GB2543307B (en) * 2015-10-14 2020-12-09 Selentus Science Ltd Haemostatic device
WO2018051205A1 (es) * 2016-09-16 2018-03-22 Universidad De Los Andes Tapón hemostático de matriz extracelular para biopsias percutáneas y aparato para su fabricación
MD1169Z (ro) * 2016-12-06 2018-02-28 Государственный Медицинский И Фармацевтический Университет "Nicolae Testemitanu" Республики Молдова Metodă de obţinere a spongiei de colagen
JP2022516123A (ja) * 2018-12-28 2022-02-24 エクセル メッド、エルエルシー バイオロジカルスキャホールド及びその製造方法
DE102019213178A1 (de) * 2019-08-30 2021-03-04 Resorba Medical Gmbh Polymerfolie und Polymertasche zur Aufnahme eines zu implantierenden medizinisch-technischen Produkts
CN111839637B (zh) * 2020-09-04 2022-05-10 青岛市市北区蓝天心理研究所 一种妇科伤口缝合辅助装置
EP4240435B1 (en) * 2020-11-05 2024-09-25 Datum Dental Ltd. Multi-layered collagen structure
CN117919517A (zh) * 2024-01-26 2024-04-26 陕西省眼科研究所 去细胞角膜基质板层组织联合生物胶泪道栓及其制备方法

Family Cites Families (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE404337A (es) 1933-02-11 1900-01-01
GB423017A (en) 1934-05-24 1935-01-23 Koninklijke Pharma Fab Nv A process and apparatus for the manufacture of threads, strings, bands, films and the like from animal fibres
GB487258A (en) 1936-02-07 1938-06-17 Koninklijke Pharma Fab Nv Tampons and other porous articles, such as sheaths and bandages, and a process for producing same
DE3105624A1 (de) 1981-02-16 1982-09-02 Hormon-Chemie München GmbH, 8000 München Material zum abdichten und heilen von wunden
US5147387A (en) 1990-10-10 1992-09-15 W. L. Gore & Associates, Inc. Process of implanting a prosthetic sheet repair material
US5290310A (en) 1991-10-30 1994-03-01 Howmedica, Inc. Hemostatic implant introducer
RU2018540C1 (ru) 1992-11-23 1994-08-30 Товарищество с ограниченной ответственностью Фирма "Копримекс" Способ получения коллагенсодержащего материала
US5334216A (en) * 1992-12-10 1994-08-02 Howmedica Inc. Hemostatic plug
US6177126B1 (en) 1993-03-31 2001-01-23 Nycomed Arzneimittel Gmbh Process for the production of a material for sealing and healing wounds
US5942278A (en) 1993-03-31 1999-08-24 Nycomed Arzneimittel Gmbh Process for the production of a material for sealing and healing wounds
AT410754B (de) * 1993-03-31 2003-07-25 Nycomed Austria Gmbh Vorrichtung zum gleichmässigen auftragen einer suspension auf einen kollagenträger
AT402683B (de) 1995-05-16 1997-07-25 Hafslund Nycomed Pharma Gerät für endoskopische oder laparoskopische applikation von chirurgischem material
DE19546435A1 (de) 1995-12-13 1997-06-19 Nycomed Arzneimittel Gmbh Vorrichtung zum Einbringen von wundheilendem oder wundversiegelnden Material in den Körper
CN1145457C (zh) * 1995-12-13 2004-04-14 奈库姆德奥地利股份有限公司 施加手术材料的器械
RU2118176C1 (ru) 1996-09-27 1998-08-27 Истранов Леонид Прокофьевич Способ получения коллагеновых пластинок
JP2001516261A (ja) 1997-03-20 2001-09-25 フォーカル・インコーポレーテッド 生物分解性の組織開創器
FR2777284B1 (fr) * 1998-04-10 2000-05-26 Hamza Mansour Procede de sterilisation d'un collagene natif en milieu liquide, collagene natif sterile obtenu, compositions le contenant et applications
DE19922078A1 (de) 1999-05-15 2000-11-23 Weitzel Kage Doris Gewebekonstrukt für die Transplantationschirurgie
US7098315B2 (en) * 2001-01-25 2006-08-29 Nycomed Pharma As Method of preparing a collagen sponge, a device for extracting a part of a collagen foam, and an elongated collagen sponge
US20020164322A1 (en) 2001-01-25 2002-11-07 Alfred Schaufler Suspension comprising fibrinogen, thrombin and alcohol, a method for preparing such a suspension, a method for coating a carrier with such a suspension, a method of drying a coating of a carrier, and a coated collagen sponge
AR032517A1 (es) * 2001-01-25 2003-11-12 Nycomed Pharma As Un metodo para preparar una esponja de colageno, un dispositivo para extraer una parte de una espuma de colageno, y una esponja de colageno alargada
US7052713B2 (en) 2001-02-13 2006-05-30 Nycomed Pharma As Carrier with solid fibrinogen and solid thrombin
AU2002307345B2 (en) 2001-04-13 2006-05-04 Avent, Inc. Sterile container for medical applications
US8465516B2 (en) * 2001-07-26 2013-06-18 Oregon Health Science University Bodily lumen closure apparatus and method
ATE294535T1 (de) * 2001-07-26 2005-05-15 Univ Oregon Health Sciences Verschlusseinrichtung für ein gefäss und anbringungsvorrichtung
TWI324524B (en) * 2002-01-25 2010-05-11 Nycomed Pharma As Carrier with solid fibrinogen and solid thrombin
WO2003065877A2 (en) 2002-02-04 2003-08-14 Damage Control Surgical Technologies, Inc. Method and apparatus for improved hemostasis and damage control operations
US7166133B2 (en) 2002-06-13 2007-01-23 Kensey Nash Corporation Devices and methods for treating defects in the tissue of a living being
JP4581318B2 (ja) 2002-08-09 2010-11-17 ニプロ株式会社 生分解性筒状体およびそれを用いた生体組織または器官再生器具
JP4168740B2 (ja) 2002-12-12 2008-10-22 ニプロ株式会社 コラーゲン製人工血管
US7329792B2 (en) 2003-02-04 2008-02-12 Damage Control Surgical Technologies, Inc. Method and apparatus for hemostasis
RU2235539C1 (ru) 2003-04-25 2004-09-10 Филатов Владимир Николаевич Способ получения порошкообразного материала для остановки кровотечений
CN1251655C (zh) * 2003-06-13 2006-04-19 常春荣 快速生物封闭止血装置及其制造工艺
US20050208095A1 (en) 2003-11-20 2005-09-22 Angiotech International Ag Polymer compositions and methods for their use
CN2705167Y (zh) * 2004-02-20 2005-06-22 佟刚 胶原贴敷料
US20050277978A1 (en) * 2004-06-09 2005-12-15 Secant Medical, Llc Three-dimensional coils for treatment of vascular aneurysms
GB0415080D0 (en) 2004-07-05 2004-08-04 Ucl Biomedica Plc Methods for preparing tissue equivalent implants and products thereof
PL1809342T3 (pl) 2004-10-20 2015-12-31 Ethicon Inc Wchłanialny hemostat
JP4995811B2 (ja) 2005-04-29 2012-08-08 クック・バイオテック・インコーポレーテッド 瘻治療用容積式移植片並びに関連の方法及びシステム
JP4765602B2 (ja) 2005-12-14 2011-09-07 ニプロ株式会社 再生医療用器具の包装体及び再生医療用器具用の処理方法
US8795709B2 (en) 2006-03-29 2014-08-05 Incept Llc Superabsorbent, freeze dried hydrogels for medical applications
RU2480191C2 (ru) * 2006-08-04 2013-04-27 ЭсТиБи ЛАЙФСЭЙВИНГ ТЕКНОЛОДЖИЗ, ИНК. Твердая повязка для лечения травмированной ткани
US8299316B2 (en) * 2007-12-18 2012-10-30 Ethicon, Inc. Hemostatic device
ES2421642T3 (es) 2008-03-03 2013-09-04 Omrix Biopharmaceuticals Ltd Una esponja de gelatina que comprende un ingrediente activo, su preparación y uso
EP2276879B1 (en) 2008-04-11 2015-11-25 Virginia Commonwealth University Electrospun dextran fibers and devices formed therefrom
US20090275129A1 (en) 2008-04-30 2009-11-05 Ethicon, Inc. Tissue engineered blood vessels
US9205170B2 (en) 2008-05-02 2015-12-08 Hemcon Medical Technologies, Inc. Wound dressing devices and methods
JP5157689B2 (ja) * 2008-07-07 2013-03-06 ニプロ株式会社 内視鏡下手術用デバイス
US9061464B2 (en) 2008-09-03 2015-06-23 Collagen Matrix, Inc. Re-rollable wrapping implant
US8529434B2 (en) 2008-10-29 2013-09-10 Cook Medical Technologies Llc Endoscopic sheet delivery
CN201342005Y (zh) * 2009-02-02 2009-11-11 沂南县天成生物制品有限公司 一种壳聚糖复合生物止血膜
US8926552B2 (en) 2009-08-12 2015-01-06 Medtronic, Inc. Particle delivery
DK3243489T3 (da) 2011-05-24 2021-05-10 Takeda As Oprullet kollagenbærer

Also Published As

Publication number Publication date
EA028878B1 (ru) 2018-01-31
EP2713972A1 (en) 2014-04-09
EP2713972B1 (en) 2017-06-28
UA113959C2 (xx) 2017-04-10
DK3243489T3 (da) 2021-05-10
EP3243489A1 (en) 2017-11-15
DK2713972T3 (en) 2017-10-09
AP2013007327A0 (en) 2013-12-31
JP2014519897A (ja) 2014-08-21
ES2871064T3 (es) 2021-10-28
MX355925B (es) 2018-05-04
MD4471B1 (ro) 2017-03-31
EP3243489B8 (en) 2022-03-23
PE20141037A1 (es) 2014-08-27
PL2713972T3 (pl) 2017-11-30
AU2012261339B2 (en) 2014-06-12
TW201300143A (zh) 2013-01-01
EA201391716A1 (ru) 2014-03-31
US20180085322A1 (en) 2018-03-29
UY34096A (es) 2018-06-29
ZA201307060B (en) 2014-05-28
PL3243489T3 (pl) 2021-11-02
EP3243489B1 (en) 2021-02-17
CN103702645B (zh) 2015-10-21
US20140072612A1 (en) 2014-03-13
CA2837117A1 (en) 2012-11-29
CO6862131A2 (es) 2014-02-10
CY1119313T1 (el) 2018-02-14
AR086557A1 (es) 2014-01-08
LT2713972T (lt) 2017-09-11
MY185054A (en) 2021-04-30
ES2642151T9 (es) 2018-01-08
BR112013029709B1 (pt) 2021-07-20
JP6025824B2 (ja) 2016-11-16
SA112330549B1 (ar) 2016-03-02
BR112013029709A2 (pt) 2020-12-15
HUE032689T2 (en) 2017-10-30
CN103702645A (zh) 2014-04-02
US9814686B2 (en) 2017-11-14
AU2012261339A1 (en) 2013-03-07
EP2713972B9 (en) 2017-11-15
IL229446A0 (en) 2014-01-30
HRP20171424T1 (hr) 2017-11-03
SI2713972T1 (sl) 2017-10-30
ME02830B (me) 2018-01-20
US10532032B2 (en) 2020-01-14
RS56367B1 (sr) 2017-12-29
MX2013013435A (es) 2014-07-09
MD20130097A2 (ro) 2014-06-30
IL229446A (en) 2017-06-29
PT2713972T (pt) 2017-09-22
KR101833035B1 (ko) 2018-02-27
KR20140033425A (ko) 2014-03-18
ES2642151T3 (es) 2017-11-15
NZ615820A (en) 2015-10-30
MD4471C1 (ro) 2017-10-31
GEP201706715B (en) 2017-08-10
WO2012159635A1 (en) 2012-11-29
CA2837117C (en) 2017-08-29
TWI552774B (zh) 2016-10-11
HUE032689T4 (en) 2017-11-28
TN2013000391A1 (en) 2015-01-20

Similar Documents

Publication Publication Date Title
CL2013003274A1 (es) Proceso para enrollar un soporte de colágeno donde se humedece al menos parte de dicho soporte de colágeno antes de enrollarlo y el cual es sostenido por un dispositivo de soporte para después secar.
ES2674445R1 (es) Procedimiento para la evaluacion de las caracteristicas de potencia de turbinas eolicas, aparatos y medios de almacenamiento
BR112016008193A2 (pt) Método para remoção de sox de gás com o uso de solução de complexo álcool-amina
EP2991390A4 (en) METHOD FOR SEARCHING WIRELESS TAGS, NON-MEMORABLE STORAGE MEDIUM FOR STORING A PROGRAM FOR LOOKING FOR WIRELESS TAGS AND DEVICE FOR SEARCHING WIRELESS TAGS
DK2796709T3 (da) Vindmøllevingeholdeindretning
CL2014002159A1 (es) Robot para girar en una tuberia que tiene un eje longitudinal y una superficie interna que incluye una circunferencia, donde el robot comprende una estructura, multiples ruedas, un mecanismo de accionamiento, donde las ruedas estan adaptadas para rodar sobre la superficie interna de la tuberia en una trayectoria helicoidal; metodo.
DK2781734T3 (da) Rotorvinge med en segmenteret støttestruktur og fremgangsmåde til fremstilling af rotorvingen
DK2886123T3 (da) Pluripotent stamcelle som inducerer reparation og regeneration efter myokardieinfarkt
BR112013029037A2 (pt) intercalação de bit paralela
DK3165766T3 (da) Vindmølle og fremgangsmåde til fjernelse af is i vindmøller
DK3259473T3 (da) Indturbinepark med trykluftenergilagre
CO6630092A2 (es) Sistema de desenrollado de metal en laminas verticales
EP3365555A4 (en) Wind turbine power storage and regeneration
ES2745466T8 (es) Recipiente con envoltura, método y aparato para producir el mismo
DK3036434T3 (da) Vindmølle med lave vindhastigheder
FI20135220A (fi) Luoti ja menetelmä luodin laajentamiseksi
CL2013000574A1 (es) Absorbedor de energia que comprende al menos un pilar hueco de nucleo relleno con refrigerante, dos superficies planas de soporte montadas en dos extremos de el al menos un pilar hueco de nucleo, y multiples primeras capas de material y multiples segundas capas de material montadas entre las superficies planas de soporte.
DK3120017T3 (da) Vindenergianlæg-rotorvinge med rotorvingetilslutning og fremstillingsfremgangsmåde
DK3058218T3 (da) Vindturbine med vandret akse udstyret med stablede blade
BR302014002560S1 (pt) Configuração aplicada em suporte para balão
CL2014001549A1 (es) Una composicion explosiva que comprende un material energetico liquido y vacios sensibilizantes que estan presentes en el material energetico con una distribucion no aleatoria, donde el material energetico comprende regiones en las cuales los vacios sensibilizantes estan suficientemente concentrados para dejar estas regiones detonables, y otras donde no estan concentrados; y metodos.
BR112016014116A2 (pt) Método para preparar células-tronco mesenquimais (mscs) de mamíferos
CL2012003301A1 (es) Aparato para indexar un dispositivo alrededor de un eje de indexacion porque el aparato comprende una base, un soporte para sujetar el dispositivo para girar alrededor del eje de indexacion, el soporte comprende un montaje giratorio alojado sobre la base para la rotacion alrededor de un eje de cabeceo transversal con respecto al eje de indexacion; herramienta y metodo.
DK3030232T3 (da) Sårheling via autolog stamecellemobilisering
BR112016000329A2 (pt) método para a recuperação e atualização de calor, e, compressor para uso na etapa c do método