CH683966A5 - Composti della classe dei ftalidrazidici come sostanze attive in agenti anti-ipossici e di difesa. - Google Patents

Composti della classe dei ftalidrazidici come sostanze attive in agenti anti-ipossici e di difesa. Download PDF

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Publication number
CH683966A5
CH683966A5 CH531/93A CH53193A CH683966A5 CH 683966 A5 CH683966 A5 CH 683966A5 CH 531/93 A CH531/93 A CH 531/93A CH 53193 A CH53193 A CH 53193A CH 683966 A5 CH683966 A5 CH 683966A5
Authority
CH
Switzerland
Prior art keywords
preparation
doses
dose
animals
administered
Prior art date
Application number
CH531/93A
Other languages
English (en)
Italian (it)
Inventor
Leonid Minin
Slava Saizev
Original Assignee
Limad Marketing Exp & Imp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Limad Marketing Exp & Imp filed Critical Limad Marketing Exp & Imp
Priority to CH531/93A priority Critical patent/CH683966A5/it
Priority to AT94102182T priority patent/ATE170847T1/de
Priority to DE69413090T priority patent/DE69413090T2/de
Priority to ES94102182T priority patent/ES2125361T3/es
Priority to EP94102182A priority patent/EP0612733B1/de
Priority to JP6021377A priority patent/JP2725994B2/ja
Priority to US08/198,896 priority patent/US5512573A/en
Publication of CH683966A5 publication Critical patent/CH683966A5/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/30—Phthalazines
    • C07D237/32—Phthalazines with oxygen atoms directly attached to carbon atoms of the nitrogen-containing ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Paints Or Removers (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CH531/93A 1993-02-19 1993-02-19 Composti della classe dei ftalidrazidici come sostanze attive in agenti anti-ipossici e di difesa. CH683966A5 (it)

Priority Applications (7)

Application Number Priority Date Filing Date Title
CH531/93A CH683966A5 (it) 1993-02-19 1993-02-19 Composti della classe dei ftalidrazidici come sostanze attive in agenti anti-ipossici e di difesa.
AT94102182T ATE170847T1 (de) 1993-02-19 1994-02-12 Verwendung von 5-amino-phthaloylhydrazid als antihypoxisches und defensives mittel
DE69413090T DE69413090T2 (de) 1993-02-19 1994-02-12 Verwendung von 5-Amino-Phthaloylhydrazid als antihypoxisches und defensives Mittel
ES94102182T ES2125361T3 (es) 1993-02-19 1994-02-12 Uso de 5-amino-ftaloilhidrazida como agente anti-hipoxico y de defensa.
EP94102182A EP0612733B1 (de) 1993-02-19 1994-02-12 Verwendung von 5-Amino-Phthaloylhydrazid als antihypoxisches und defensives Mittel
JP6021377A JP2725994B2 (ja) 1993-02-19 1994-02-18 抗低酸素症薬および防御薬としてのフタロイルヒドラジド誘導体の使用
US08/198,896 US5512573A (en) 1993-02-19 1994-02-18 Use of phthaloylhydrazide derivatives as anti-hypoxic and defensive agents

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH531/93A CH683966A5 (it) 1993-02-19 1993-02-19 Composti della classe dei ftalidrazidici come sostanze attive in agenti anti-ipossici e di difesa.

Publications (1)

Publication Number Publication Date
CH683966A5 true CH683966A5 (it) 1994-06-30

Family

ID=4189148

Family Applications (1)

Application Number Title Priority Date Filing Date
CH531/93A CH683966A5 (it) 1993-02-19 1993-02-19 Composti della classe dei ftalidrazidici come sostanze attive in agenti anti-ipossici e di difesa.

Country Status (7)

Country Link
US (1) US5512573A (de)
EP (1) EP0612733B1 (de)
JP (1) JP2725994B2 (de)
AT (1) ATE170847T1 (de)
CH (1) CH683966A5 (de)
DE (1) DE69413090T2 (de)
ES (1) ES2125361T3 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH683965A5 (it) * 1993-02-19 1994-06-30 Limad Marketing Exp & Imp Composti della classe dei ftalidrazidici come sostanza attiva in agenti antinfiammatori ed antitossici.
EP1203587B1 (de) 2000-03-28 2010-07-14 Abidov, Musea Tazhudinovich Arzneimittel und dessen herstellungsprozess
US7326690B2 (en) 2002-10-30 2008-02-05 Bach Pharma, Inc. Modulation of cell fates and activities by phthalazinediones
US6953799B1 (en) * 2002-10-30 2005-10-11 Bach Pharma, Inc. Modulation of cell fates and activities by diketo phthalazines
US8592421B2 (en) 2003-08-04 2013-11-26 Valery Khazhmuratovich Zhilov Cyclic bioisosters of purine system derivatives and a pharmaceutical composition based thereon
PL231885B1 (pl) 2009-01-16 2019-04-30 Abidopharma Spolka Z Ograniczona Odpowiedzialnoscia Sposób wytwarzania soli 5-amino-2,3-dihydroftalazyno-1,4-di onu z metalami alkalicznymi, ich kompozycje farmaceutyczne i ich zastosowanie
CA2751270C (en) * 2009-02-06 2018-01-09 Bach Pharma, Inc. Pharmaceutical grade phthalazinediones, process for their preparation and pharmaceutical compositions containing them
JP6061081B2 (ja) * 2010-03-01 2017-01-18 メトリオファーム アーゲー ５−アミノ−２，３−ジヒドロフタラジン−１，４−ジオンナトリウム塩の結晶形ｉまたはｉｉ、それを含有する医薬品調製物、５−アミノ−２，３−ジヒドロフタラジン−１，４−ジオンナトリウム塩の結晶形ｉの製造方法、および５−アミノ−２，３−ジヒドロフタラジン−１，４−ジオンナトリウム塩の結晶形ｉｉの製造方法
CN102382115B (zh) * 2011-10-14 2014-06-11 浙江工业大学 一种吲唑并酞嗪化合物的合成方法
RU2532128C1 (ru) * 2013-05-22 2014-10-27 Закрытое акционерное общество "Управляющая компания "Световит" Способ получения о-люминолятов щелочных металлов
WO2016096143A1 (de) 2014-12-18 2016-06-23 Metriopharm Ag Kristalline form von 5-amino-2,3-dihydrophthalazin-1,4-dion natriumsalz, diese enthaltende pharmazeutische zubereitungen und verfahren zu ihrer herstellung
EP3416951B1 (de) * 2016-02-16 2020-04-08 MetrioPharm AG Krystalline form von 5-amino-2,3-dihydrophthalazine-1,4-dione

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2420702A (en) * 1944-06-28 1947-05-20 British Celanese Amino-aliphatic hydrazines and process for making same
US3007937A (en) * 1959-06-04 1961-11-07 Du Pont Synthesis of 5-(4-aminobutyl) hydantoin
NL6908330A (de) * 1968-06-12 1969-12-16
US3870792A (en) * 1972-07-24 1975-03-11 Michiro Inoue Certain dihydrophthalizines for treating hemorrhage and thrombosis
US4318505A (en) * 1980-08-12 1982-03-09 Cordell Jr Charles E Disposable suitcase
WO1982000641A1 (en) * 1980-08-25 1982-03-04 Ab Kabivitrum Peptide substrates for determination of protease activity
HU181184B (en) * 1980-09-12 1983-06-28 Eszakmagyar Vegyimuevek Composition for replacing kinetine,the effect and membraneactivity of which is similar to citokinine,which composition improves plant productivity,quantity of protein-nitrogen and anion-absorptivity

Also Published As

Publication number Publication date
DE69413090T2 (de) 1999-08-19
DE69413090D1 (de) 1998-10-15
ATE170847T1 (de) 1998-09-15
JPH07188022A (ja) 1995-07-25
JP2725994B2 (ja) 1998-03-11
EP0612733B1 (de) 1998-09-09
US5512573A (en) 1996-04-30
EP0612733A1 (de) 1994-08-31
ES2125361T3 (es) 1999-03-01

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Legal Events

Date Code Title Description
PUE Assignment

Owner name: L.I.M.A.D. MARKETING EXPORT & IMPORT ANSTALT -DANN

PUE Assignment

Owner name: L.I.M.A.D. LIMITED TRANSFER- ZSM "MEDIKOR"

PL Patent ceased