CH673655A5 - - Google Patents
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- Publication number
- CH673655A5 CH673655A5 CH2936/87A CH293687A CH673655A5 CH 673655 A5 CH673655 A5 CH 673655A5 CH 2936/87 A CH2936/87 A CH 2936/87A CH 293687 A CH293687 A CH 293687A CH 673655 A5 CH673655 A5 CH 673655A5
- Authority
- CH
- Switzerland
- Prior art keywords
- phe
- boc
- isobutyl
- tetrafluoro
- trifluoro
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0227—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the (partial) peptide sequence -Phe-His-NH-(X)2-C(=0)-, e.g. Renin-inhibitors with n = 2 - 6; for n > 6 see C07K5/06 - C07K5/10
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB868619182A GB8619182D0 (en) | 1986-08-06 | 1986-08-06 | Peptides & derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
CH673655A5 true CH673655A5 (da) | 1990-03-30 |
Family
ID=10602311
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CH2936/87A CH673655A5 (da) | 1986-08-06 | 1987-07-31 |
Country Status (7)
Country | Link |
---|---|
JP (1) | JPS6348295A (da) |
BE (1) | BE1001618A4 (da) |
CH (1) | CH673655A5 (da) |
DE (1) | DE3725137A1 (da) |
FR (1) | FR2602511A1 (da) |
GB (2) | GB8619182D0 (da) |
IT (1) | IT1211681B (da) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5071837A (en) * | 1990-11-28 | 1991-12-10 | Warner-Lambert Company | Novel renin inhibiting peptides |
CA2098020C (en) * | 1991-01-02 | 2003-10-21 | Daniel Schirlin | Anti-viral compounds |
ES2152982T3 (es) * | 1993-07-08 | 2001-02-16 | Merrell Pharma Inc | Analogos de la difluoroestatona. |
ES2133573T3 (es) * | 1993-09-09 | 1999-09-16 | Merrell Pharma Inc | Analogos antiviricos de difluoro estatone. |
US6114380A (en) * | 1995-12-18 | 2000-09-05 | Merrell Pharmaceuticals Inc. | Difluoro statone analogs |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FI88400C (fi) * | 1984-08-06 | 1993-05-10 | Upjohn Co | Foerfarande foer framstaellning av renin inhiberande peptider |
ZA86746B (en) * | 1985-02-04 | 1986-09-24 | Merrell Dow Pharma | Novel peptidase inhibitors |
CH672792A5 (da) * | 1985-02-19 | 1989-12-29 | Sandoz Ag | |
WO1986006379A1 (en) * | 1985-04-19 | 1986-11-06 | The Upjohn Company | Dihalo-statine substituted renin inhibitors |
WO1987002675A1 (en) * | 1985-11-01 | 1987-05-07 | Pfizer Inc. | Difluorocyclostatine containing polypeptides |
ES2056930T3 (es) * | 1987-07-01 | 1994-10-16 | Pfizer | Inhibidores de la renina que contienen fluor. |
JPH10183253A (ja) * | 1996-12-24 | 1998-07-14 | Nisshin Steel Co Ltd | 表面性状及び加工性に優れた冷延鋼板又は溶融めっき鋼板の製造方法 |
-
1986
- 1986-08-06 GB GB868619182A patent/GB8619182D0/en active Pending
-
1987
- 1987-07-27 FR FR8710662A patent/FR2602511A1/fr not_active Withdrawn
- 1987-07-27 BE BE8700830A patent/BE1001618A4/fr not_active IP Right Cessation
- 1987-07-28 IT IT8748235A patent/IT1211681B/it active
- 1987-07-29 DE DE19873725137 patent/DE3725137A1/de not_active Withdrawn
- 1987-07-31 CH CH2936/87A patent/CH673655A5/de not_active IP Right Cessation
- 1987-08-03 GB GB8718325A patent/GB2196958B/en not_active Expired - Lifetime
- 1987-08-05 JP JP62196151A patent/JPS6348295A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
GB8718325D0 (en) | 1987-09-09 |
GB8619182D0 (en) | 1986-09-17 |
FR2602511A1 (fr) | 1988-02-12 |
GB2196958B (en) | 1990-07-04 |
GB2196958A (en) | 1988-05-11 |
JPS6348295A (ja) | 1988-02-29 |
DE3725137A1 (de) | 1988-02-11 |
IT8748235A0 (it) | 1987-07-28 |
BE1001618A4 (fr) | 1989-12-19 |
IT1211681B (it) | 1989-11-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PL | Patent ceased |