CH643566A5 - 25-alkylcholesterin-derivate. - Google Patents

25-alkylcholesterin-derivate. Download PDF

Info

Publication number
CH643566A5
CH643566A5 CH906378A CH906378A CH643566A5 CH 643566 A5 CH643566 A5 CH 643566A5 CH 906378 A CH906378 A CH 906378A CH 906378 A CH906378 A CH 906378A CH 643566 A5 CH643566 A5 CH 643566A5
Authority
CH
Switzerland
Prior art keywords
parts
methylcholest
formula
radical
diol
Prior art date
Application number
CH906378A
Other languages
German (de)
English (en)
Inventor
Robert John Chorvat
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Publication of CH643566A5 publication Critical patent/CH643566A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CH906378A 1977-08-29 1978-08-28 25-alkylcholesterin-derivate. CH643566A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US82838577A 1977-08-29 1977-08-29

Publications (1)

Publication Number Publication Date
CH643566A5 true CH643566A5 (de) 1984-06-15

Family

ID=25251653

Family Applications (1)

Application Number Title Priority Date Filing Date
CH906378A CH643566A5 (de) 1977-08-29 1978-08-28 25-alkylcholesterin-derivate.

Country Status (9)

Country Link
JP (1) JPS5448751A (it)
AU (1) AU520334B2 (it)
CA (1) CA1113086A (it)
CH (1) CH643566A5 (it)
DE (1) DE2837414A1 (it)
ES (1) ES472877A1 (it)
FR (1) FR2401935A1 (it)
GB (1) GB2009180B (it)
IT (1) IT1106121B (it)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4225525A (en) * 1979-02-08 1980-09-30 Hoffmann-La Roche Inc. Vitamin D3 metabolite derivatives
US4230626A (en) * 1979-07-30 1980-10-28 G. D. Searle & Co. 25-Halocholest-5-ene-3β,22-diols and esters thereof
US4329295A (en) * 1981-06-29 1982-05-11 G. D. Searle & Co. 24-Cyclopropylcholene-3β, 22-diols and esters thereof
US4348328A (en) * 1981-11-09 1982-09-07 G.D. Searle & Co. 25-Substituted-5α-cholestane-3β,22S-diol
IL105050A0 (en) * 1992-03-27 1993-07-08 Lilly Co Eli Steroid derivatives
DK1163258T3 (da) * 1999-03-09 2003-03-31 Akzo Nobel Nv Derivater af 22R-hydroxycholesta-8, 14-dien til inhiberingen af meiosis
CN1498222A (zh) * 2001-02-08 2004-05-19 芝加哥大学 类固醇衍生物
US7078396B2 (en) 2001-05-03 2006-07-18 Arch Development Corporation Method of treating disorder related to high cholesterol concentration
EP2459581A4 (en) 2009-07-29 2012-12-26 Univ Chicago LIVER X RECEPTOR AGONISTS

Also Published As

Publication number Publication date
CA1113086A (en) 1981-11-24
GB2009180B (en) 1982-05-26
DE2837414A1 (de) 1979-03-08
ES472877A1 (es) 1979-02-16
FR2401935B1 (it) 1981-07-10
FR2401935A1 (fr) 1979-03-30
JPS5448751A (en) 1979-04-17
IT1106121B (it) 1985-11-11
AU3931878A (en) 1980-03-06
AU520334B2 (en) 1982-01-28
GB2009180A (en) 1979-06-13
IT7850879A0 (it) 1978-08-28
DE2837414C2 (it) 1987-09-03
JPS6259720B2 (it) 1987-12-12

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Legal Events

Date Code Title Description
PL Patent ceased