JPS5448751A - 255alkylcholesterol derivative - Google Patents

255alkylcholesterol derivative

Info

Publication number
JPS5448751A
JPS5448751A JP10480878A JP10480878A JPS5448751A JP S5448751 A JPS5448751 A JP S5448751A JP 10480878 A JP10480878 A JP 10480878A JP 10480878 A JP10480878 A JP 10480878A JP S5448751 A JPS5448751 A JP S5448751A
Authority
JP
Japan
Prior art keywords
derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP10480878A
Other languages
English (en)
Other versions
JPS6259720B2 (ja
Inventor
Jiyon Shiyuubatsuto Robaato
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GD Searle LLC
Original Assignee
GD Searle LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GD Searle LLC filed Critical GD Searle LLC
Publication of JPS5448751A publication Critical patent/JPS5448751A/ja
Publication of JPS6259720B2 publication Critical patent/JPS6259720B2/ja
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J53/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J9/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP10480878A 1977-08-29 1978-08-28 255alkylcholesterol derivative Granted JPS5448751A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US82838577A 1977-08-29 1977-08-29

Publications (2)

Publication Number Publication Date
JPS5448751A true JPS5448751A (en) 1979-04-17
JPS6259720B2 JPS6259720B2 (ja) 1987-12-12

Family

ID=25251653

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10480878A Granted JPS5448751A (en) 1977-08-29 1978-08-28 255alkylcholesterol derivative

Country Status (9)

Country Link
JP (1) JPS5448751A (ja)
AU (1) AU520334B2 (ja)
CA (1) CA1113086A (ja)
CH (1) CH643566A5 (ja)
DE (1) DE2837414A1 (ja)
ES (1) ES472877A1 (ja)
FR (1) FR2401935A1 (ja)
GB (1) GB2009180B (ja)
IT (1) IT1106121B (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002539134A (ja) * 1999-03-09 2002-11-19 アクゾ・ノベル・エヌ・ベー 減数分裂の阻害のための22r−ヒドロキシコレスタ−8,14−ジエン誘導体

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4225525A (en) * 1979-02-08 1980-09-30 Hoffmann-La Roche Inc. Vitamin D3 metabolite derivatives
US4230626A (en) * 1979-07-30 1980-10-28 G. D. Searle & Co. 25-Halocholest-5-ene-3β,22-diols and esters thereof
US4329295A (en) * 1981-06-29 1982-05-11 G. D. Searle & Co. 24-Cyclopropylcholene-3β, 22-diols and esters thereof
US4348328A (en) * 1981-11-09 1982-09-07 G.D. Searle & Co. 25-Substituted-5α-cholestane-3β,22S-diol
IL105050A0 (en) * 1992-03-27 1993-07-08 Lilly Co Eli Steroid derivatives
CN1498222A (zh) * 2001-02-08 2004-05-19 芝加哥大学 类固醇衍生物
US7078396B2 (en) 2001-05-03 2006-07-18 Arch Development Corporation Method of treating disorder related to high cholesterol concentration
EP2459581A4 (en) 2009-07-29 2012-12-26 Univ Chicago LIVER X RECEPTOR AGONISTS

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002539134A (ja) * 1999-03-09 2002-11-19 アクゾ・ノベル・エヌ・ベー 減数分裂の阻害のための22r−ヒドロキシコレスタ−8,14−ジエン誘導体

Also Published As

Publication number Publication date
CA1113086A (en) 1981-11-24
GB2009180B (en) 1982-05-26
DE2837414A1 (de) 1979-03-08
CH643566A5 (de) 1984-06-15
ES472877A1 (es) 1979-02-16
FR2401935B1 (ja) 1981-07-10
FR2401935A1 (fr) 1979-03-30
IT1106121B (it) 1985-11-11
AU3931878A (en) 1980-03-06
AU520334B2 (en) 1982-01-28
GB2009180A (en) 1979-06-13
IT7850879A0 (it) 1978-08-28
DE2837414C2 (ja) 1987-09-03
JPS6259720B2 (ja) 1987-12-12

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