CH636615A5 - Pharmaceutically effective, optionally substituted imidazo(1,5-d)-as-triazin-4-(3H)-ones and -thiones - Google Patents

Pharmaceutically effective, optionally substituted imidazo(1,5-d)-as-triazin-4-(3H)-ones and -thiones Download PDF

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Publication number
CH636615A5
CH636615A5 CH114578A CH114578A CH636615A5 CH 636615 A5 CH636615 A5 CH 636615A5 CH 114578 A CH114578 A CH 114578A CH 114578 A CH114578 A CH 114578A CH 636615 A5 CH636615 A5 CH 636615A5
Authority
CH
Switzerland
Prior art keywords
methyl
phenyl
carbon atoms
imidazo
group
Prior art date
Application number
CH114578A
Other languages
German (de)
English (en)
Inventor
Rolf Paul
Judith Menschik
Bryant Leonidas Walworth
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/843,174 external-priority patent/US4107307A/en
Priority claimed from US05/848,836 external-priority patent/US4124766A/en
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of CH636615A5 publication Critical patent/CH636615A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30—Oxygen or sulfur atoms
    • C07D233/40—Two or more oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/68—Halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
CH114578A 1977-02-03 1978-02-02 Pharmaceutically effective, optionally substituted imidazo(1,5-d)-as-triazin-4-(3H)-ones and -thiones CH636615A5 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US76531877A 1977-02-03 1977-02-03
US76531777A 1977-02-03 1977-02-03
US84317377A 1977-10-18 1977-10-18
US05/843,174 US4107307A (en) 1977-02-03 1977-10-18 Imidazo [1,5-d]-as-triazine-4(3H)-ones and thiones
US05/848,836 US4124766A (en) 1977-02-03 1977-11-07 Substituted 3-(4-imidazolylmethylene)carbazic and thiocarbazic acid esters

Publications (1)

Publication Number Publication Date
CH636615A5 true CH636615A5 (en) 1983-06-15

Family

ID=27542181

Family Applications (1)

Application Number Title Priority Date Filing Date
CH114578A CH636615A5 (en) 1977-02-03 1978-02-02 Pharmaceutically effective, optionally substituted imidazo(1,5-d)-as-triazin-4-(3H)-ones and -thiones

Country Status (15)

Country Link
JP (1) JPS596316B2 (sv)
AR (1) AR224613A1 (sv)
BE (1) BE863567A (sv)
CA (1) CA1097638A (sv)
CH (1) CH636615A5 (sv)
DE (1) DE2804435A1 (sv)
DK (1) DK48778A (sv)
FR (1) FR2384772A1 (sv)
GB (1) GB1597671A (sv)
GR (1) GR73810B (sv)
IE (1) IE46511B1 (sv)
IL (1) IL53783A (sv)
NL (1) NL7801230A (sv)
SE (1) SE7801270L (sv)
YU (1) YU22078A (sv)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3212749A1 (de) * 1982-04-06 1983-10-13 Basf Ag, 6700 Ludwigshafen Neue 5-substituierte 4-methylimidazole und verfahren zu ihrer herstellung
DE3302413A1 (de) * 1983-01-21 1984-07-26 Schering AG, 1000 Berlin und 4709 Bergkamen Triazinone, verfahren zur herstellung dieser verbindungen sowie diese enthaltende mittel mit selektiver herbizider wirkung
JPS6337712A (ja) * 1986-08-01 1988-02-18 Hitachi Ltd 電界効果トランジスタの保護回路
JPH02185069A (ja) * 1988-12-02 1990-07-19 Motorola Inc 高エネルギー阻止能力及び温度補償された阻止電圧を具備する半導体デバイス
RU2103262C1 (ru) * 1992-07-16 1998-01-27 Лонца АГ Гампель/Валлис Способ получения 2-замещенных 5-хлоримидазол-4-карбальдегидов
US5484939A (en) * 1993-03-12 1996-01-16 Lonza Ltd. 2-substituted 5-chlorimidazoles
US5442075A (en) * 1993-03-12 1995-08-15 Lonza Ltd. Process for the production of 2-substituted 5-chlorimidazole-4-carbaldehydes
EP0614890B1 (de) * 1993-03-12 1997-09-03 Lonza AG Verfahren zur Herstellung von gegebenfalls 2-substituierten 5-Chlorimidazolen
CA2135541C (en) * 1993-11-15 2006-01-10 Gareth Griffiths Process for the preparation of 2-substituted 5-chloroimidazole-4-carbaldehydes
CA2175420C (en) * 1995-05-17 2007-04-10 Gareth Griffiths Process for the preparation of optionally 2-substituted 5-chloroimidazole-4-carbaldehydes
JP4103149B2 (ja) 1996-01-05 2008-06-18 ロンザ リミテッド ２−置換５−クロロイミダゾール−４−カルブアルデヒドの製造方法
FR2842809A1 (fr) * 2002-07-26 2004-01-30 Greenpharma Sas NOUVELLES PYRAZOLO[1,5-a]-1,3,5-TRIAZINES SUBSTITUEES ET LEURS ANALOGUES, COMPOSITIONS PHARMACEUTIQUES LES CONTENANT, UTILISATION A TITRE DE MEDICAMENT ET PROCEDES POUR LEUR PREPARATION

Also Published As

Publication number Publication date
IE46511B1 (en) 1983-07-13
JPS5398994A (en) 1978-08-29
YU22078A (en) 1983-12-31
AR224613A1 (es) 1981-12-30
SE7801270L (sv) 1978-09-29
GB1597671A (en) 1981-09-09
DK48778A (da) 1978-08-04
DE2804435A1 (de) 1978-08-17
IL53783A (en) 1982-08-31
IL53783A0 (en) 1978-04-30
FR2384772A1 (fr) 1978-10-20
JPS596316B2 (ja) 1984-02-10
IE780208L (en) 1978-08-03
BE863567A (fr) 1978-08-02
CA1097638A (en) 1981-03-17
GR73810B (sv) 1984-04-17
NL7801230A (nl) 1978-08-07

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